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Cited by 97

The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.

EBI2 Is Highly Expressed in Multiple Sclerosis Lesions and Promotes Early CNS Migration of Encephalitogenic CD4 T Cells

Wanke, Florian, Moos, Sonja, Croxford, Andrew L., Heinen, André P., Gräf, Stephanie, Kalt, Bettina, Tischner, Denise, Zhang, Juan, Christen, Isabelle, Bruttger, Julia, Yogev, Nir, Tang, Yilang, Zayoud, Morad, Israel, Nicole, Karram, Khalad, Reißig, Sonja, Lacher, Sonja M., Reichhold, Christian, Mufazalov, Ilgiz A., Ben-Nun, Avraham, Kuhlmann, Tanja, Wettschureck, Nina, Sailer, Andreas W., Rajewsky, Klaus, Casola, Stefano, Waisman, Ari, Kurschus, Florian C.·2017·Cell Reports
DOI 10.1016/j.celrep.2017.01.020
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Crossref · 10.1016/j.celrep.2017.01.020

Cites

8 of 8 references verified0 citation errors · 0 not checkable

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  • In a mouse model of experimental autoimmune encephalomyelitis, expression of Gpr183 was demonstrated in a variety of T cells and was shown to be required for the encephalitogenic T cell infiltration into the brain.

    “In a mouse model of experimental autoimmune encephalomyelitis, expression of Gpr183 was demonstrated in a variety of T cells and was shown to be required for the encephalitogenic T cell infiltration into the brain (Wanke et al., 2017).”

    From Cholesterol 25-hydroxylase mediates neuroinflammation and neurodegeneration in a mouse model of tauopathy (2024) · cites this paper as Wanke et al., 2017

    The ‘EBI2 Expression in T Cells Regulates Their Migration’ section reports Gpr183/EBI2 expression across several T-cell subsets. The ‘EBI2 Expression Confers Pathogenicity to Myelin-Specific Th17 Cells’ section reports reduced CNS entry by EBI2-deficient encephalitogenic T cells, but also finds that those cells can infiltrate the tissue. The paper supports a role in promoting or accelerating infiltration, not that Gpr183 is required for it. (LLM, conf=0.90)

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Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 29

  1. Babbe, 2000, Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction, J. Exp. Med., 192, 393, 10.1084/jem.192.3.393 · DOI · Paper page
  2. Benned-Jensen, 2013, Small molecule antagonism of oxysterol-induced Epstein-Barr virus induced gene 2 (EBI2) activation, FEBS Open Bio, 3, 156, 10.1016/j.fob.2013.02.003 · DOI
  3. Birkenbach, 1993, Epstein-Barr virus-induced genes: first lymphocyte-specific G protein-coupled peptide receptors, J. Virol., 67, 2209, 10.1128/jvi.67.4.2209-2220.1993 · DOI
  4. Cardona, 2006, Isolation of murine microglial cells for RNA analysis or flow cytometry, Nat. Protoc., 1, 1947, 10.1038/nprot.2006.327 · DOI · Paper page
  5. Chalmin, 2015, Oxysterols regulate encephalitogenic CD4 T cell trafficking during central nervous system autoimmunity, J. Autoimmun., 56, 45, 10.1016/j.jaut.2014.10.001 · DOI · Paper page
  6. Chung, 2009, Critical regulation of early Th17 cell differentiation by interleukin-1 signaling, Immunity, 30, 576, 10.1016/j.immuni.2009.02.007 · DOI
  7. Croxford, 2015, The cytokine GM-CSF drives the inflammatory signature of CCR2+ monocytes and licenses autoimmunity, Immunity, 43, 502, 10.1016/j.immuni.2015.08.010 · DOI · Paper page
  8. Gatto, 2009, Guidance of B cells by the orphan G protein-coupled receptor EBI2 shapes humoral immune responses, Immunity, 31, 259, 10.1016/j.immuni.2009.06.016 · DOI
  9. Gatto, 2013, The chemotactic receptor EBI2 regulates the homeostasis, localization and immunological function of splenic dendritic cells, Nat. Immunol., 14, 446, 10.1038/ni.2555 · DOI
  10. Gessier, 2014, Identification and characterization of small molecule modulators of the Epstein-Barr virus-induced gene 2 (EBI2) receptor, J. Med. Chem., 57, 3358, 10.1021/jm4019355 · DOI
  11. Hannedouche, 2011, Oxysterols direct immune cell migration via EBI2, Nature, 475, 524, 10.1038/nature10280 · DOI
  12. Heinen, 2014, Improved method to retain cytosolic reporter protein fluorescence while staining for nuclear proteins, Cytometry A, 85, 621, 10.1002/cyto.a.22451 · DOI
  13. Hirota, 2011, Fate mapping of IL-17-producing T cells in inflammatory responses, Nat. Immunol., 12, 255, 10.1038/ni.1993 · DOI · Paper page
  14. Huang, 2006, The neuronal chemokine CX3CL1/fractalkine selectively recruits NK cells that modify experimental autoimmune encephalomyelitis within the central nervous system, FASEB J., 20, 896, 10.1096/fj.05-5465com · DOI
  15. Kelly, 2008, Agonist-selective mechanisms of GPCR desensitization, Br. J. Pharmacol., 153, S379
  16. Kurschus, 2010, Genetic proof for the transient nature of the Th17 phenotype, Eur. J. Immunol., 40, 3336, 10.1002/eji.201040755 · DOI
  17. Laurence, 2007, Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation, Immunity, 26, 371, 10.1016/j.immuni.2007.02.009 · DOI · Paper page
  18. Lee, 2012, Induction and molecular signature of pathogenic T(H)17 cells, Nat. Immunol., 13, 991, 10.1038/ni.2416 · DOI · Paper page
  19. Li, 2016, EBI2 augments Tfh cell fate by promoting interaction with IL-2-quenching dendritic cells, Nature, 533, 110, 10.1038/nature17947 · DOI
  20. Liu, 2010, The S1P(1)-mTOR axis directs the reciprocal differentiation of T(H)1 and T(reg) cells, Nat. Immunol., 11, 1047, 10.1038/ni.1939 · DOI
  21. Liu, 2011, Oxysterols direct B-cell migration through EBI2, Nature, 475, 519, 10.1038/nature10226 · DOI · Paper page
  22. Olah, 2012, Identification of a microglia phenotype supportive of remyelination, Glia, 60, 306, 10.1002/glia.21266 · DOI · Paper page
  23. Pereira, 2009, EBI2 mediates B cell segregation between the outer and centre follicle, Nature, 460, 1122, 10.1038/nature08226 · DOI
  24. Rutkowska, 2015, EBI2 regulates intracellular signaling and migration in human astrocyte, Glia, 63, 341, 10.1002/glia.22757 · DOI
  25. Rutkowska, 2016, The EBI2 signalling pathway plays a role in cellular crosstalk between astrocytes and macrophages, Sci. Rep., 6, 25520, 10.1038/srep25520 · DOI
  26. Suan, 2015, T follicular helper cells have distinct modes of migration and molecular signatures in naive and memory immune responses, Immunity, 42, 704, 10.1016/j.immuni.2015.03.002 · DOI
  27. Yi, 2013, EBI2-mediated bridging channel positioning supports splenic dendritic cell homeostasis and particulate antigen capture, eLife, 2, e00757, 10.7554/eLife.00757 · DOI
  28. Yi, 2012, Oxysterol gradient generation by lymphoid stromal cells guides activated B cell movement during humoral responses, Immunity, 37, 535, 10.1016/j.immuni.2012.06.015 · DOI
  29. Zayoud, 2013, Subclinical CNS inflammation as response to a myelin antigen in humanized mice, J. Neuroimmune Pharmacol., 8, 1037, 10.1007/s11481-013-9466-4 · DOI

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Metadata

Authors
Wanke, F., Moos, S., Croxford, A. L., Heinen, A. P., Gräf, S., Kalt, B., Tischner, D., Zhang, J., Christen, I., Bruttger, J., Yogev, N., Tang, Y., Zayoud, M., Israel, N., Karram, K., Reißig, S., Lacher, S. M., Reichhold, C., Mufazalov, I. A., Ben-Nun, A., Kuhlmann, T., Wettschureck, N., Sailer, A. W., Rajewsky, K., Casola, S., Waisman, A., & Kurschus, F. C.
Venue
Cell Reports
Publisher
Elsevier BV
Published
2017-01
Volume
18
Issue
5
Pages
1270-1284
ISSN
2211-1247
DOI
10.1016/j.celrep.2017.01.020
Cited by
97
References
8
Language
en
Licence
Funders
  • Deutsche Forschungsgemeinschaft (SFB/TR-128 TPA3, TPA7, TPZ1, SFB/TR-156 TP C01)
  • Italian Association for Cancer Research (AIRC)

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