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Juicer Provides a One-Click System for Analyzing Loop-Resolution Hi-C Experiments

Open access
Durand, Neva C., Shamim, Muhammad S., Machol, Ido, Rao, Suhas S.P., Huntley, Miriam H., Lander, Eric S., Aiden, Erez Lieberman·2016·Cell Systems

Abstract

Hi-C experiments explore the 3D structure of the genome, generating terabases of data to create high-resolution contact maps. Here, we introduce Juicer, an open-source tool for analyzing terabase-scale Hi-C datasets. Juicer allows users without a computational background to transform raw sequence data into normalized contact maps with one click. Juicer produces a hic file containing compressed contact matrices at many resolutions, facilitating visualization and analysis at multiple scales. Structural features, such as loops and domains, are automatically annotated. Juicer is available as open source software at http://aidenlab.org/juicer/.

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Research works printed but not linked: 7

  1. Durand, 2016, Juicebox Provides a Visualization System for Hi-C Contact Maps with Unlimited Zoom, Cell Systems, 3, 99, 10.1016/j.cels.2015.07.012 · DOI · Paper page
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Metadata

Authors
Durand, N. C., Shamim, M. S., Machol, I., Rao, S. S. P., Huntley, M. H., Lander, E. S., & Aiden, E. L.
Venue
Cell Systems
Publisher
Elsevier BV
Published
2016-07
Volume
3
Issue
1
Pages
95-98
ISSN
2405-4712 (ISSN-L)
OpenAlex
W2481029670
Cited by
3,836
References
2
FWCI
39.12
Type
journal article
Language
en
Open access
hybrid
Licence

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CoChat. (2026). Citation check: Juicer Provides a One-Click System for Analyzing Loop-Resolution Hi-C Experiments. https://app.cochat.ai/papers/10.1016/j.cels.2016.07.002
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Durand, N. C., Shamim, M. S., Machol, I., Rao, S. S. P., Huntley, M. H., Lander, E. S., & Aiden, E. L. (2016). Juicer Provides a One-Click System for Analyzing Loop-Resolution Hi-C Experiments. Cell Systems. https://doi.org/10.1016/j.cels.2016.07.002

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