Bioceramic fibrous scaffolds built with calcium silicate/hydroxyapatite nanofibers showing advantages for bone regeneration
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In acidic environments, PLCL degradation rate is usually faster due to increased hydrolysis of ester bonds, whereas alkaline conditions slow degradation.
“In acidic environments, the degradation rate of PLCL is usually faster. This is due to acidic conditions that increase the hydrolysis of ester bonds in the polymer chain. However, alkaline conditions will slow the degradation of the material [46, 47].”
From Application of PLCL as a biodegradable polymer in biomedical engineering (2026) · cites this paper as [47]
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Application of PLCL as a biodegradable polymer in biomedical engineering
Zhao, Y., & Liu, H. (2026) · Journal of Materials Science Materials in Medicine · doi:10.1007/s10856-026-07016-3 · Cited by 7 · see citing works
- Authors
- Zheng, T., Guo, L., Du, Z., Leng, H., Cai, Q., & Yang, X.
- Affiliations
- State Key Laboratory of Organic-Inorganic Composite Materials (CN)
- Peking University Third Hospital (CN)
- Corresponding author
- Leng, Huijie
- Cai, Qing
- Venue
- Ceramics International
- Publisher
- Elsevier BV
- Published
- 2021-07
- Volume
- 47
- Issue
- 13
- Pages
- 18920-18930
- ISSN
- 0272-8842 (ISSN-L)
- OpenAlex
- W3142546894
- Cited by
- 39
- References
- 55
- Citations by year
- 2026: 2 · 2025: 9 · 2024: 10 · 2023: 8 · 2022: 7 · 2021: 3
- FWCI
- 2.13
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Ceramics International (publishedVersion)
- Funders
- National Natural Science Foundation of China (51873013)
- National Key Research and Development Program of China (2017YFC1104302/4300)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Bone Tissue Engineering Materials
- Physical Sciences › Materials Science › Biomaterials › Electrospun Nanofibers in Biomedical Applications
- Physical Sciences › Materials Science › Biomaterials › biodegradable polymer synthesis and properties
- Keywords
- hydroxyapatite nanowires, bioceramic scaffolds, bone regeneration, composite scaffolds, polymer coatings, poly(L-lactic acid), poly(L-lactide-co-ε-caprolactone), gelatin coating, scaffold degradation rate, ion release, pH control, osteogenic differentiation, bone marrow mesenchymal stromal cells
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