Cited by 323Nutrition and Health in AgingObesity, Physical Activity, DietBody Composition Measurement Techniques

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The Obesity Paradox in the Elderly: Potential Mechanisms and Clinical Implications

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Oreopoulos, Antigone, Kalantar-Zadeh, Kamyar, Sharma, Arya M., Fonarow, Gregg C.·2009·Clinics in Geriatric Medicine

DOI 10.1016/j.cger.2009.07.005

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Abstract

The prevalence of overweight and obesity in the elderly has become a growing concern. Recent evidence indicates that in the elderly, obesity is paradoxically associated with a lower, not higher, mortality risk. Although obesity in the general adult population is associated with higher mortality, this relationship is unclear for persons of advanced age and has lead to great controversy regarding the relationship between obesity and mortality in the elderly, the definition of obesity in the elderly, and the need for its treatment in this population. This article examines the evidence on these controversial issues, explores potential explanations for these findings, discusses the clinical implications, and provides recommendations for further research in this area.

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Authors: Oreopoulos, A., Kalantar-Zadeh, K., Sharma, A. M., & Fonarow, G. C.
Affiliations: University of Alberta (CA)
University of California, Los Angeles (US)
Corresponding author: Oreopoulos, Antigone
ORCID: Sharma, Arya M.
Fonarow, Gregg C.
Venue: Clinics in Geriatric Medicine
Publisher: Elsevier BV
Published: 2009-11
Volume: 25
Issue: 4
Pages: 643-659
ISSN: 0749-0690 (ISSN-L)
DOI: 10.1016/j.cger.2009.07.005
OpenAlex: W1997453905
Cited by: 323
References: 114
Citations by year: 2026: 10 · 2025: 9 · 2024: 23 · 2023: 12 · 2022: 25 · 2021: 26 · 2020: 26 · 2019: 12 · 2018: 13 · 2017: 19 · 2016: 33 · 2015: 20 · 2014: 23 · 2013: 21 · 2012: 23
FWCI: 1.87
Type: journal article
Language: en
Open access: green
escholarship.org
Licence: cc-by
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Clinics in Geriatric Medicine (publishedVersion)
PubMed (publishedVersion)
eScholarship (California Digital Library) (submittedVersion, cc-by)
Topics: Health Sciences › Medicine › Physiology (medical) › Nutrition and Health in Aging
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
Health Sciences › Medicine › Physiology (medical) › Body Composition Measurement Techniques
Keywords: obesity paradox, older adults, obesity, mortality risk, overweight, obesity definition, obesity treatment
MeSH terms: Activities of Daily Living, Adult, Age Factors, Aged, Aged, 80 and over, Cardiovascular Diseases, Cause of Death, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Nutrition Surveys, Obesity, Physical Fitness, Quality of Life, Risk, Sex Factors, Weight Loss, Body Mass Index, Survival Rate

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The Obesity Paradox in the Elderly: Potential Mechanisms and Clinical Implications

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