The DOI matches its Crossref record; 83 of the 83 references it cites were found in a registry or an index.
The Prevalence and Diagnostic Utility of Endoscopic Features of Eosinophilic Esophagitis: A Meta-analysis
Open accessAbstract
Background & Aims Endoscopic findings such as esophageal rings, strictures, narrow-caliber esophagus, linear furrows, white plaques, and pallor or decreased vasculature might indicate the presence of eosinophilic esophagitis (EoE). We aimed to determine the prevalence and diagnostic utility of endoscopic features of EoE. Methods We conducted a systematic review and meta-analysis. PubMed, EMBASE, and GI meeting abstracts were searched to identify studies that included ≥ 10 patients with EoE and reported endoscopic findings. Pooled prevalence, sensitivity, specificity, and predictive values were calculated using random- and mixed-effects models. Results The search yielded 100 articles and abstracts on 4678 patients with EoE and 2742 without (controls). In subjects with EoE, the overall pooled prevalence of esophageal rings was 44%, strictures 21%, narrow-caliber esophagus 9%, linear furrows 48%, white plaques 27%, and pallor/decreased vasculature 41%. Substantial heterogeneity existed among studies. Results from endoscopy examinations were normal in 17% of patients, but this number decreased to 7% when the analysis was limited to prospective studies (P<.05). Overall levels of sensitivity were modest, ranging from 15% to 48%, whereas levels of specificity were greater, ranging from 90% to 95%. Positive predictive values ranged from 51% to 73% and negative predictive values ranged from 74% to 84%. Conclusions There is heterogeneity among studies in the reported prevalence of endoscopic findings in patients with EoE, but in prospective studies, at least 1 abnormality was detected by endoscopy in 93% of patients. The operating characteristics of endoscopic findings alone are inadequate for diagnosis of EoE. Esophageal biopsies should be obtained from all patients with clinical features of EoE, regardless of the endoscopic appearance of the esophagus.
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Cites
Quantifying heterogeneity in a meta‐analysis
Higgins, J. P. T., & Thompson, S. G. (2002) · Statistics in Medicine · doi:10.1002/sim.1186 · Cited by 36,763
Eosinophilic esophagitis: Updated consensus recommendations for children and adults
Liacouras, C. A., Furuta, G. T., Hirano, I., Atkins, D., Attwood, S. E., Bonis, P. A., Burks, A. W., Chehade, M., Collins, M. H., Dellon, E. S., et al. (2011) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2011.02.040 · Cited by 2,073
Self-citationFuruta, G. T., Liacouras, C. A., Collins, M. H., Gupta, S. K., Justinich, C., Putnam, P. E., Bonis, P., Hassall, E., Straumann, A., & Rothenberg, M. E. (2007) · Gastroenterology · doi:10.1053/j.gastro.2007.08.017 · Cited by 1,673
Esophageal eosinophilia with dysphagia: A distinct clinicopathologic syndrome
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Eosinophilic Esophagitis: A 10-Year Experience in 381 Children
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Konikoff, M. R., Noel, R. J., Blanchard, C., Kirby, C., Jameson, S. C., Buckmeier, B. K., Akers, R., Cohen, M. B., Collins, M. H., Assa’ad, A. H., et al. (2006) · Gastroenterology · doi:10.1053/j.gastro.2006.08.033 · Cited by 585
Elemental diet is an effective treatment for eosinophilic esophagitis in children and adolescents
Markowitz, J. (2003) · The American Journal of Gastroenterology · doi:10.1016/s0002-9270(03)00054-6 · Cited by 563
Budesonide Is Effective in Adolescent and Adult Patients With Active Eosinophilic Esophagitis
Straumann, A., Conus, S., Degen, L., Felder, S., Kummer, M., Engel, H., Bussmann, C., Beglinger, C., Schoepfer, A., & Simon, H. (2010) · Gastroenterology · doi:10.1053/j.gastro.2010.07.048 · Cited by 524
Epidemiology of Eosinophilic Esophagitis Over Three Decades in Olmsted County, Minnesota
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Cited by
Dellon, E. S., Liacouras, C. A., Molina-Infante, J., Furuta, G. T., Spergel, J. M., Zevit, N., Spechler, S. J., Attwood, S. E., Straumann, A., Aceves, S. S., et al. (2018) · Gastroenterology · doi:10.1053/j.gastro.2018.07.009 · Cited by 1,162
Self-citationDellon, E. S., Gonsalves, N., Hirano, I., Furuta, G. T., Liacouras, C. A., & Katzka, D. A. (2013) · American Journal of Gastroenterology · doi:10.1038/ajg.2013.71 · Cited by 1,159
Self-citationFood allergy: A practice parameter update—2014
Sampson, H. A., Aceves, S., Bock, S. A., James, J., Jones, S., Lang, D., Nadeau, K., Nowak-Wegrzyn, A., Oppenheimer, J., Perry, T. T., et al. (2014) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2014.05.013 · Cited by 845
Prevalence of Eosinophilic Esophagitis in the United States
Dellon, E. S., Jensen, E. T., Martin, C. F., Shaheen, N. J., & Kappelman, M. D. (2014) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2013.09.008 · Cited by 444
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Metadata
- Authors
- Kim, H. P., Vance, R. B., Shaheen, N. J., & Dellon, E. S.
- Venue
- Clinical Gastroenterology and Hepatology
- Publisher
- Elsevier BV
- Published
- 2012-09
- Volume
- 10
- Issue
- 9
- Pages
- 988-996.e5
- ISSN
- 1542-3565 (ISSN-L)
- OpenAlex
- W2004630542
- Cited by
- 368
- References
- 83
- FWCI
- 5.10
- Type
- journal article
- Language
- en
- Open access
- green
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