Microtubule Interactions with Chemically Diverse Stabilizing Agents: Thermodynamics of Binding to the Paclitaxel Site Predicts Cytotoxicity

Buey, Rubén M., Barasoain, Isabel, Jackson, Evelyn, Meyer, Arndt, Giannakakou, Paraskevi, Paterson, Ian, Mooberry, Susan, Andreu, José M., Díaz, J. Fernando·2005·Chemistry & Biology
DOI 10.1016/j.chembiol.2005.09.010

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  12. Docking Studies of the Binding Mode of Dictyostatin and Its Analogues to the Taxoid Binding Site on Beta Tubulin
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  17. Finding the Binding Site of Peloruside A and its Secondary Effects in Saccharomyces Cerevisiae using a Chemical Genetics Approach
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  20. Taxane-Induced Conformational Changes in the Microtubule Lattice Activate GEF-H1-Dependent RhoA Signaling
    Joyce C. M. Meiring, Varsha Mahapatra, Molly S. C. Gravett, Daan Morren, Harriet A. J. Saunders, Sung Ryul Choi, Andressa Pelster Jose, Adela Karhanova, Ioanna Metallidou, Alex Moore et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
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  23. Caractérisation du système microtubulaire par analyse top-down et protéomique d'affinité
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  25. Dissecting Structural and Functional Determinants of Microtubules Stabilization through Guided Chemical Modulation
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  26. Fibrinogen–Drug Nanoparticles Achieve Durable Responses in Pancreatic and Breast Cancer Murine Models
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  27. BindingDB Entry 50020778: PM534, an Optimized Target-Protein Interaction Strategy through the Colchicine Site of Tubulin.
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  28. BindingDB Entry 50006617: Antitumor Activity of Lankacidin Group Antibiotics Is Due to Microtubule Stabilization via a Paclitaxel-like Mechanism.
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