CoChat
Sign Up
Cited by 113Pharmaceutical and Antibiotic Environmental ImpactsWastewater Treatment and ReuseAntibiotic Use and Resistance

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Antibiotic resistance development and human health risks during wastewater reuse and biosolids application in agriculture

Sorinolu, Adeola Julian, Tyagi, Neha, Kumar, Arun, Munir, Mariya·2021·Chemosphere
DOI 10.1016/j.chemosphere.2020.129032
Open this paper in CoChat — free account

Abstract

The reuse of treated wastewater (TWW) and sewage sludge are considered as solutions to the limited water resource and sludge disposal issues, respectively. The associated environmental and human health risks need to be analyzed to assess whether they are safe solutions or not. This paper discusses issues that relate to the accumulation of antibiotics and antibiotic resistance (AR) determinants in agricultural lands and crops, following TWW irrigation and biosolid amendment. Exposure assessment and dose-response assessment are the two important aspects of risk assessment discussed in this paper. Finally, research gaps in current knowledge that are relevant to a comprehensive and quantitative AR risk assessment were identified which includes: 1.) Studies on soil conditions that increase the frequency of horizontal gene transfer (HGT) between native soil resistome and pathogenic microbes in biosolids and TWW 2.) Holistic studies that examine the accumulation or dissipation of antibiotics, antibiotic resistant bacteria (ARB) and antibiotic resistance genes (ARGs) from the irrigation/biosolids application stage to crop consumption stage 3.) The influences of soil environmental conditions (e.g. salinity, nutrients) on the fate of ARB and ARGs in soil and translocation in edible plants 4.) The development of dose-response models that explicitly incorporate the potential for ARGs transfer between microbes when quantifying the risks of infection due to ARB.

Overview

Integrity signals

Registry

Crossref · 10.1016/j.chemosphere.2020.129032

Cites

2 of 2 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Show all 2 references

Research works printed but not linked: 112

  1. Akinbowale, 2007, Antibiotic and heavy metal resistance in motile aeromonads and pseudomonads from rainbow trout (Oncorhynchus mykiss) farms in Australia, Int. J. Antimicrob. Agents, 30, 177, 10.1016/j.ijantimicag.2007.03.012 · DOI
  2. Al-Jassim, 2015, Removal of bacterial contaminants and antibiotic resistance genes by conventional wastewater treatment processes in Saudi Arabia: is the treated wastewater safe to reuse for agricultural irrigation?, Water Res., 73, 277, 10.1016/j.watres.2015.01.036 · DOI
  3. Alygizakis, 2020, Evaluation of chemical and biological contaminants of emerging concern in treated wastewater intended for agricultural reuse, Environ. Int., 138, 105597, 10.1016/j.envint.2020.105597 · DOI
  4. Amarasiri, 2019, Understanding human health risks caused by antibiotic resistant bacteria (ARB) and antibiotic resistance genes (ARG) in water environments: current knowledge and questions to be answered, Crit. Rev. Environ. Sci. Technol.
  5. Ashbolt, 2013, Human health risk assessment (HHRA) for environmental development and transfer of antibiotic resistance, Environ. Health Perspect., 121, 993, 10.1289/ehp.1206316 · DOI
  6. Auerbach, 2007, Tetracycline resistance genes in activated sludge wastewater treatment plants, Water Res., 41, 1143, 10.1016/j.watres.2006.11.045 · DOI
  7. Azanu, 2016, Uptake of antibiotics from irrigation water by plants, Chemosphere, 157, 107, 10.1016/j.chemosphere.2016.05.035 · DOI
  8. Baker-Austin, 2006, Co-selection of antibiotic and metal resistance, Trends Microbiol., 14, 176, 10.1016/j.tim.2006.02.006 · DOI
  9. Becerra-Castro, 2015, Wastewater reuse in irrigation: a microbiological perspective on implications in soil fertility and human and environmental health, Environ. Int., 75, 117, 10.1016/j.envint.2014.11.001 · DOI
  10. Ben, 2019, Human health risk assessment of antibiotic resistance associated with antibiotic residues in the environment: a review, Environ. Res., 169, 483, 10.1016/j.envres.2018.11.040 · DOI
  11. Berendonk, 2015, Tackling antibiotic resistance: the environmental framework, Nat. Rev. Microbiol., 13, 310, 10.1038/nrmicro3439 · DOI
  12. Berglund, 2015, Environmental dissemination of antibiotic resistance genes and correlation to anthropogenic contamination with antibiotics, Infect. Ecol. Epidemiol., 5, 28564
  13. Bondarczuk, 2016, The urgent need for risk assessment on the antibiotic resistance spread via sewage sludge land application, Environ. Int., 87, 49, 10.1016/j.envint.2015.11.011 · DOI
  14. Calero-Cáceres, 2016, Persistence of naturally occurring antibiotic resistance genes in the bacteria and bacteriophage fractions of wastewater, Water Res., 95, 11, 10.1016/j.watres.2016.03.006 · DOI
  15. Cerqueira, 2019, 177, 108608
  16. Chander, 2005, Antibacterial activity of soil-bound antibiotics, J. Environ. Qual., 34, 1952, 10.2134/jeq2005.0017 · DOI
  17. Chandrasekeran, 2019, A dose-response model for quantifying the infection risk of antibiotic-resistant bacteria, Sci. Rep., 9, 17093, 10.1038/s41598-019-52947-3 · DOI
  18. Chang, 2015, Antibiotics in agriculture and the risk to human health: how worried should we be?, Evolutionary Applications, 8, 240, 10.1111/eva.12185 · DOI
  19. Chen, 2013, Effects of advanced treatment systems on the removal of antibiotic resistance genes in wastewater treatment plants from Hangzhou, China, Environ. Sci. Technol., 47, 8157
  20. Christou, 2016, Stress-related phenomena and detoxification mechanisms induced by common pharmaceuticals in alfalfa (Medicago sativa L.) plants, Sci. Total Environ., 652, 10.1016/j.scitotenv.2016.03.054 · DOI
  21. Christou, 2017, The potential implications of reclaimed wastewater reuse for irrigation on the agricultural environment: the knowns and unknowns of the fate of antibiotics and antibiotic resistant bacteria and resistance genes–a review, Water Res., 123, 448, 10.1016/j.watres.2017.07.004 · DOI · Paper page
  22. Clarke, 2011, Review of “emerging” organic contaminants in biosolids and assessment of international research priorities for the agricultural use of biosolids, Environ. Int., 37, 226, 10.1016/j.envint.2010.06.004 · DOI
  23. Cytryn, 2013, The soil resistome: the anthropogenic, the native, and the unknown, Soil Biol. Biochem., 63, 18, 10.1016/j.soilbio.2013.03.017 · DOI
  24. del Mar Alguacil, 2012, Long-term effects of irrigation with wastewater on soil AM fungi diversity and microbial activities: the implications for agro-ecosystem resilience, PloS One, 7, 10.1371/journal.pone.0047680 · DOI
  25. D’Angelo, 2017, Sorption-desorption equilibrium and diffusion of tetracycline in poultry litter and municipal biosolids soil amendments, Chemosphere, 188, 494, 10.1016/j.chemosphere.2017.09.015 · DOI
  26. Ekpeghere, 2017, Determination and characterization of pharmaceuticals in sludge from municipal and livestock wastewater treatment plants, Chemosphere, 168, 1211, 10.1016/j.chemosphere.2016.10.077 · DOI
  27. EMEA, 1998, Maximum Residue Limit. Enrofloxacin (modification for bovine, porcine and poultry), Summary report, 1
  28. Ensink, 2006, Giardia duodenalis infection and wastewater irrigation in Pakistan, Trans. R. Soc. Trop. Med. Hyg., 100, 538, 10.1016/j.trstmh.2005.08.014 · DOI
  29. Fleming, 1945, Sir Alexander Fleming - Nobel Lecture: penicillin, Nobel Media
  30. Franklin, 2016, Uptake of three antibiotics and an antiepileptic drug by wheat crops spray irrigated with wastewater treatment plant effluent, J. Environ. Qual., 45, 546, 10.2134/jeq2015.05.0257 · DOI
  31. Gao, 2012, Correlation of tetracycline and sulfonamide antibiotics with corresponding resistance genes and resistant bacteria in a conventional municipal wastewater treatment plant, Sci. Total Environ., 173, 10.1016/j.scitotenv.2012.01.061 · DOI
  32. Gatica, 2013, Impact of treated wastewater irrigation on antibiotic resistance in the soil microbiome, Environ. Sci. Pollut. Control Ser., 20, 3529, 10.1007/s11356-013-1505-4 · DOI
  33. Giger, 2003, Occurrence and fate of antibiotics as trace contaminants in wastewaters, sewage sludges, and surface waters, Chimia, 57, 485, 10.2533/000942903777679064 · DOI
  34. Grossberger, 2014, Biodegradability of pharmaceutical compounds in agricultural soils irrigated with treated wastewater, Environ. Pollut., 185, 168, 10.1016/j.envpol.2013.10.038 · DOI
  35. Gumbo, 2010, The health implications of wastewater reuse in vegetable irrigation: a case study from Malamulele, South Africa, Int. J. Environ. Health Res., 20, 10.1080/09603120903511093 · DOI
  36. Guo, 2017, Metagenomic analysis reveals wastewater treatment plants as hotspots of antibiotic resistance genes and mobile genetic elements, Water Res., 123, 468, 10.1016/j.watres.2017.07.002 · DOI
  37. Haas, 2015, Microbial dose response modelling: past, present, and future, Environ. Sci. Technol., 49, 1245, 10.1021/es504422q · DOI
  38. Hasman, 2002, tcrB, a gene conferring transferable copper resistance in Enterococcus faecium: occurrence, transferability, and linkage to macrolide and glycopeptide resistance, Antimicrob. Agents Chemother., 46, 1410, 10.1128/AAC.46.5.1410-1416.2002 · DOI
  39. Helmecke, 2020, Regulating water reuse for agricultural irrigation: risks related to organic micro-contaminants, Environ. Sci. Eur., 32, 4, 10.1186/s12302-019-0283-0 · DOI
  40. Hong, 2018, Reusing treated wastewater: consideration of the safety aspects associated with antibiotic-resistant bacteria and antibiotic resistance genes, Water, 10, 244, 10.3390/w10030244 · DOI
  41. Ibekwe, 2018, Impact of treated wastewater for irrigation on soil microbial communities, Sci. Total Environ., 622, 1603, 10.1016/j.scitotenv.2017.10.039 · DOI
  42. Jia, 2008, Adsorption and cosorption of Cu (II) and tetracycline on two soils with different characteristics, Geoderma, 146, 224, 10.1016/j.geoderma.2008.05.023 · DOI
  43. Kim, 2005, Removal of antibiotics in wastewater: effect of hydraulic and solid retention times on the fate of tetracycline in the activated sludge process, Environ. Sci. Technol., 39, 5816, 10.1021/es050006u · DOI
  44. Kiziloglu, 2007, Effects of wastewater irrigation on soil and cabbage-plant (brassica olerecea var. capitate cv. yalova-1) chemical properties, J. Plant Nutr. Soil Sci., 170, 166, 10.1002/jpln.200621971 · DOI
  45. Kong, 2006, The veterinary antibiotic oxytetracycline and Cu influence functional diversity of the soil microbial community, Environ. Pollut., 143, 129, 10.1016/j.envpol.2005.11.003 · DOI
  46. Kumar, 2010, Human health risk assessment of pharmaceuticals in water: an uncertainty analysis for meprobamate, carbamazepine, and phenytoin, Regul. Toxicol. Pharmacol., 57, 146, 10.1016/j.yrtph.2010.02.002 · DOI
  47. Kumar, 2010, Human health risk assessment of pharmaceuticals in water: issues and challenges ahead, Int. J. Environ. Res. Publ. Health, 7, 3929, 10.3390/ijerph7113929 · DOI
  48. Laht, 2014, Abundances of tetracycline, sulphonamide and beta-lactam antibiotic resistance genes in conventional wastewater treatment plants (WWTPs) with different waste load, PloS One, 9, 10.1371/journal.pone.0103705 · DOI
  49. Larsson, 2018, Critical knowledge gaps and research needs related to the environmental dimensions of antibiotic resistance, Environ. Int., 117, 132, 10.1016/j.envint.2018.04.041 · DOI
  50. Leonard, 2015, Human recreational exposure to antibiotic resistant bacteria in coastal bathing waters, Environ. Int., 82, 92, 10.1016/j.envint.2015.02.013 · DOI
  51. Li, 2015, Metagenomic and network analysis reveal wide distribution and co-occurrence of environmental antibiotic resistance genes, ISME J., 9, 2490, 10.1038/ismej.2015.59 · DOI
  52. Li, 2017, Co-occurrence of antibiotic and metal resistance genes revealed in complete genome collection, ISME J., 11, 651, 10.1038/ismej.2016.155 · DOI
  53. Li, 2018, Occurrence and distribution of antibiotic resistance genes in the sediments of drinking water sources, urban rivers, and coastal areas in Zhuhai, China, Environ. Sci. Pollut. Control Ser., 25, 26209, 10.1007/s11356-018-2664-0 · DOI
  54. Lu, 2020, Fate of antibiotic resistance genes in reclaimed water reuse system with integrated membrane process, J. Hazard Mater., 382, 121025, 10.1016/j.jhazmat.2019.121025 · DOI
  55. Malchi, 2014, Irrigation of root vegetables with treated wastewater: evaluating uptake of pharmaceuticals and the associated human health risks, Environ. Sci. Technol., 48, 9325, 10.1021/es5017894 · DOI
  56. Manaia, 2017, Assessing the risk of antibiotic resistance transmission from the environment to humans: non-direct proportionality between abundance and risk, Trends Microbiol., 25, 173, 10.1016/j.tim.2016.11.014 · DOI
  57. Mao, 2015, Prevalence and proliferation of antibiotic resistance genes in two municipal wastewater treatment plants, Water Res., 85, 458, 10.1016/j.watres.2015.09.010 · DOI
  58. Marsoni, 2014, Uptake and effects of a mixture of widely used therapeutic drugs in Eruca sativa L. and Zea mays L. plants, Ecotoxicol. Environ. Saf., 108, 52, 10.1016/j.ecoenv.2014.05.029 · DOI
  59. Matyar, 2012, Antibiotic and heavy metal resistance in bacteria isolated from the Eastern Mediterranean Sea coast, Bull. Environ. Contam. Toxicol., 89, 551, 10.1007/s00128-012-0726-4 · DOI
  60. McLain, 2017, Environmental antibiotic resistance associated with land application of biosolids, Antimicrobial Resistance in the Wastewater Treatment Process, 241, 10.1002/9781119192428.ch13 · DOI
  61. McMahon, 2007, Environmental stress and antibiotic resistance in food-related pathogens, Appl. Environ. Microbiol., 73, 211, 10.1128/AEM.00578-06 · DOI · Paper page
  62. Michael-Kordatou, 2018, The role of operating parameters and oxidative damage mechanisms of advanced chemical oxidation processes in the combat against antibiotic-resistant bacteria and resistance genes present in urban wastewater, Water Res., 129, 208, 10.1016/j.watres.2017.10.007 · DOI
  63. Miller, 2013, Effect of silver nanoparticles and antibiotics on antibiotic resistance genes in anaerobic digestion, Water Environ. Res., 85, 411, 10.2175/106143012X13373575831394 · DOI
  64. Miller, 2016, Root uptake of pharmaceuticals and personal care product ingredients, Environ. Sci. Technol., 50, 525, 10.1021/acs.est.5b01546 · DOI
  65. Munir, 2011, Levels of antibiotic resistance genes in manure, biosolids, and fertilized soil, J. Environ. Qual., 40, 248, 10.2134/jeq2010.0209 · DOI
  66. Munir, 2011, Release of antibiotic resistant bacteria and genes in the effluent and biosolids of five wastewater utilities in Michigan, Water Res., 45, 681, 10.1016/j.watres.2010.08.033 · DOI
  67. Negreanu, 2012, Impact of treated wastewater irrigation on antibiotic resistance in agricultural soils, Environ. Sci. Technol., 46, 4800, 10.1021/es204665b · DOI
  68. Oun, 2014, Effects of biosolids and manure application on microbial water quality in rural areas in the US, Water, 6, 3701, 10.3390/w6123701 · DOI
  69. Pal, 2015, Co-occurrence of resistance genes to antibiotics, biocides and metals reveals novel insights into their co-selection potential, BMC Genom., 16, 964, 10.1186/s12864-015-2153-5 · DOI
  70. Pal, 2017, Metal resistance and its association with antibiotic resistance, vol. 70, 261
  71. Paltiel, 2016, Human exposure to wastewater-derived pharmaceuticals in fresh produce: a randomized controlled trial focusing on carbamazepine, Environ. Sci. Technol., 50, 4476, 10.1021/acs.est.5b06256 · DOI
  72. Pan, 2017, Fate of antibiotics in soil and their uptake by edible crops, Sci. Total Environ., 599, 500, 10.1016/j.scitotenv.2017.04.214 · DOI
  73. Pan, 2014, Distribution of antibiotics in wastewater-irrigated soils and their accumulation in vegetable crops in the Pearl River Delta, Southern China, J. Agric. Food Chem., 62, 11062, 10.1021/jf503850v · DOI
  74. Pepper, 2018, Antibiotic resistant bacteria in municipal wastes: is there reason for concern?, Environ. Sci. Technol., 52, 3949, 10.1021/acs.est.7b04360 · DOI
  75. Piña, 2020, On the contribution of reclaimed wastewater irrigation to the potential exposure of humans to antibiotics, antibiotic resistant bacteria and antibiotic resistance genes–NEREUS COST Action ES1403 position paper, Journal of Environmental Chemical Engineering, 8, 102131, 10.1016/j.jece.2018.01.011 · DOI
  76. Prosser, 2015, Human health risk assessment of pharmaceuticals and personal care products in plant tissue due to biosolids and manure amendments, and wastewater irrigation, Environ. Int., 75, 223, 10.1016/j.envint.2014.11.020 · DOI
  77. Pruden, 2012, Correlation between upstream human activities and riverine antibiotic resistance genes, Environ. Sci. Technol., 46, 11541, 10.1021/es302657r · DOI
  78. Qiu, 2012, Nanoalumina promotes the horizontal transfer of multiresistance genes mediated by plasmids across genera, Proc Nat Acad Sci USA, 109, 4944, 10.1073/pnas.1107254109 · DOI
  79. Rahube, 2014, Impact of fertilizing with raw or anaerobically digested sewage sludge on the abundance of antibiotic-resistant coliforms, antibiotic resistance genes, and pathogenic bacteria in soil and on vegetables at harvest, Appl. Environ. Microbiol., 80, 6898, 10.1128/AEM.02389-14 · DOI
  80. Rattan, 2005, Long-term impact of irrigation with sewage effluents on heavy metal content in soils, crops and groundwater—a case study, Agric. Ecosyst. Environ., 109, 310, 10.1016/j.agee.2005.02.025 · DOI
  81. Riemenschneider, 2016, Pharmaceuticals, their metabolites, and other polar pollutants in field-grown vegetables irrigated with treated municipal wastewater, J. Agric. Food Chem., 64, 5784, 10.1021/acs.jafc.6b01696 · DOI
  82. Rousk, 2010, Soil bacterial and fungal communities across a pH gradient in an arable soil, ISME J., 4, 1340, 10.1038/ismej.2010.58 · DOI
  83. Seiler, 2012, Heavy metal driven co-selection of antibiotic resistance in soil and water bodies impacted by agriculture and aquaculture, Front. Microbiol., 3, 399, 10.3389/fmicb.2012.00399 · DOI · Paper page
  84. Sharma, 2016, A review of the influence of treatment strategies on antibiotic resistant bacteria and antibiotic resistance genes, Chemosphere, 150, 702, 10.1016/j.chemosphere.2015.12.084 · DOI
  85. Snary, 2004, Antimicrobial resistance: a microbial risk assessment perspective, J. Antimicrob. Chemother., 53, 906, 10.1093/jac/dkh182 · DOI
  86. Soumet, 2012, Resistance to phenicol compounds following adaptation to quaternary ammonium compounds in Escherichia coli, Vet. Microbiol., 158, 147, 10.1016/j.vetmic.2012.01.030 · DOI
  87. Srikanth, 2004, Health effects of wastewater reuse for agriculture in the suburbs of Asmara City, Eritrea, Int. J. Occup. Environ. Health, 10, 284, 10.1179/oeh.2004.10.3.284 · DOI
  88. Templeton, 2009, Chlorine and UV disinfection of ampicillin-resistant and trimethoprim-resistant Escherichia coli, Can. J. Civ. Eng., 36, 889, 10.1139/L09-040 · DOI
  89. Tong, 2019, Microbial community evolution and fate of antibiotic resistance genes along six different full-scale municipal wastewater treatment processes, Bioresour. Technol., 272, 489, 10.1016/j.biortech.2018.10.079 · DOI
  90. UNESCO, 2020, United nations world water development report 2020: Water and climate change, UNESCO, Paris
  91. US EPA, 1999, Wastewater technology fact sheet chlorine disinfection, Office of Water Washington, D.C
  92. US EPA, 2012, Guidelines for water reuse, Office of Wastewater Management, D. C., EPA/600/R-12/618, 1
  93. Wan, 2010, Simultaneous adsorption and desorption of cadmium and tetracycline on cinnamon soil, Chemosphere, 80, 807, 10.1016/j.chemosphere.2010.04.066 · DOI
  94. Wang, 2015, Adsorption behavior of antibiotic in soil environment: a critical review, Front. Environ. Sci. Eng., 9, 565, 10.1007/s11783-015-0801-2 · DOI
  95. Wang, 2014, Impact of reclaimed water irrigation on antibiotic resistance in public parks, Beijing, China, Environ. Pollut., 184, 247, 10.1016/j.envpol.2013.08.038 · DOI
  96. Wang, 2020, Synergistic effect of UV/chlorine in bacterial inactivation, resistance gene removal, and gene conjugative transfer blocking, Water Res., 185, 116290, 10.1016/j.watres.2020.116290 · DOI
  97. Wardwell, 2009, Co-selection of mercury and antibiotic resistance in sphagnum core samples dating back 2000 years, Geomicrobiol. J., 26, 351, 10.1080/01490450902889072 · DOI
  98. Weidner, 2015, Bacterial diversity amplifies nutrient-based plant–soil feedbacks, Funct. Ecol., 29, 1341, 10.1111/1365-2435.12445 · DOI
  99. WHO, 1989, Health guidelines for the use of wastewater in agriculture and aquaculture, Report of a WHO scientific group. WHO. Geneva., 778, 1
  100. WHO, 2017, World priority list of antibiotic-resistant bacteria to Guide research, Discovery, and development of new antibiotics, WHO Press., 1
  101. Xu, 2015, Occurrence of antibiotics and antibiotic resistance genes in a sewage treatment plant and its effluent-receiving river, Chemosphere, 119, 1379, 10.1016/j.chemosphere.2014.02.040 · DOI
  102. Yang, 2018, Application of biosolids drives the diversity of antibiotic resistance genes in soil and lettuce at harvest, Soil Biol. Biochem., 122, 131, 10.1016/j.soilbio.2018.04.017 · DOI
  103. Yu, 2018, A newly synthesized Au/GO-Co3O4 composite effectively inhibits the replication of tetracycline resistance gene in water, Chem. Eng. J., 345, 462, 10.1016/j.cej.2018.03.108 · DOI
  104. Yuan, 2018, Antibiotic resistance genes and intI1 prevalence in a swine wastewater treatment plant and correlation with metal resistance, bacterial community and wastewater parameters, Ecotoxicol. Environ. Saf., 161, 251, 10.1016/j.ecoenv.2018.05.049 · DOI
  105. Zammit, 2020, Changes in antibiotic resistance gene levels in soil after irrigation with treated wastewater: a comparison between heterogeneous photocatalysis and chlorination, Environ. Sci. Technol., 54, 7677, 10.1021/acs.est.0c01565 · DOI · Paper page
  106. Zhang, 2009, Tetracycline resistance genes and tetracycline resistant lactose-fermenting Enterobacteriaceae in activated sludge of sewage treatment plants, Environ. Sci. Technol., 43, 3455, 10.1021/es803309m · DOI
  107. Zhang, 2018, Sub-inhibitory concentrations of heavy metals facilitate the horizontal transfer of plasmid-mediated antibiotic resistance genes in water environment, Environ. Pollut., 237, 74, 10.1016/j.envpol.2018.01.032 · DOI · Paper page
  108. Zhang, 2019, Transfer of antibiotic resistance from manure-amended soils to vegetable microbiomes, Environ. Int., 130, 104912, 10.1016/j.envint.2019.104912 · DOI
  109. Zhang, 2020, Antibiotic resistance genes might serve as new indicators for wastewater contamination of coastal waters: Spatial distribution and source apportionment of antibiotic resistance genes in a coastal bay, Ecol. Indicat., 114, 106299, 10.1016/j.ecolind.2020.106299 · DOI
  110. Zhao, 2013, Interactions of tetracycline with Cd (II), Cu (II) and Pb (II) and their cosorption behavior in soils, Environ. Pollut., 180, 206, 10.1016/j.envpol.2013.05.043 · DOI
  111. Zhu, 2018, Changes in bacterial community structure and antibiotic resistance genes in soil in the vicinity of a pharmaceutical factory, Ecotoxicol. Environ. Saf., 158, 87, 10.1016/j.ecoenv.2018.04.016 · DOI
  112. Zhuang, 2015, Inactivation of antibiotic resistance genes in municipal wastewater by chlorination, ultraviolet, and ozonation disinfection, Environ. Sci. Pollut. Control Ser., 22, 7037, 10.1007/s11356-014-3919-z · DOI

Cited by

Sorted by citations

Metadata

Authors
Sorinolu, A. J., Tyagi, N., Kumar, A., & Munir, M.
Affiliations
  • University of North Carolina at Charlotte (US)
  • Indian Institute of Technology Delhi (IN)
Corresponding author
Munir, Mariya
ORCID
Venue
Chemosphere
Publisher
Elsevier BV
Published
2021-02
Volume
265
Pages
129032
ISSN
0045-6535 (ISSN-L)
DOI
10.1016/j.chemosphere.2020.129032
OpenAlex
W3106839103
Cited by
113
References
2
Citations by year
2026: 9 · 2025: 16 · 2024: 26 · 2023: 24 · 2022: 22 · 2021: 16
FWCI
0.68
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • Chemosphere (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Indian Institute of Technology Delhi
  • University of North Carolina at Charlotte
Topics
  • Physical Sciences › Environmental Science › Pollution › Pharmaceutical and Antibiotic Environmental Impacts
  • Physical Sciences › Environmental Science › Waste Management and Disposal › Wastewater Treatment and Reuse
  • Health Sciences › Medicine › Infectious Diseases › Antibiotic Use and Resistance
Keywords
antibiotic resistance, antibiotic resistance genes, antibiotic resistance determinants, treated wastewater reuse, biosolids, sewage sludge, agricultural irrigation, human health risk assessment, exposure assessment, dose-response assessment, horizontal gene transfer, soil resistome, antibiotic-resistant bacteria, soil salinity, soil nutrients, dose-response modeling
MeSH terms
Biosolids, Agriculture, Angiotensin-Converting Enzyme Inhibitors, Anti-Bacterial Agents, Drug Resistance, Microbial, Humans, Angiotensin Receptor Antagonists, Wastewater

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review