Establishing clinically and theoretically grounded cross-domain cumulative risk and protection scores in sibling groups exposed prenatally to substances
Abstract
Background Prenatal substance exposure is associated with neurodevelopmental deficits. Deficits are exacerbated by cumulative risks yet attenuated by cumulative protective factors. Cross-domain relative to intra-domain risk exposure presents more neurodevelopmental challenges. Cumulative risk and protection scores must be clinically and theoretically grounded, with cross-domain considerations.Objectives 1) Create clinically and theoretically grounded, cross-domain cumulative risk and protection scores; 2) Describe the benefits of our methodological approach.Participants & setting This study included three sibling groups (N = 8) at Mothercraft's Breaking the Cycle, a child maltreatment prevention and early intervention program for substance using mothers and their children.Method We outlined the process of establishing clinically and theoretically grounded, cross-domain cumulative risk and protection scores. Total and cross-domain cumulative risk and protection percentages, and the balance between domains of risk and protection, were explored.Results Clinically and theoretically grounded, cross-domain cumulative risk and protection scores were established. Total percentages were reported. Cross-domain profiles of cumulative risk and protection, and the number of significant domains of risk relative to protection, were reported. The cross-domain profiles facilitated consideration of intra- and inter-domain risk and protection within and between sibling groups.Conclusions Emerging patterns indicate the importance of establishing cumulative risk and protection scores that are: 1) clinically and theoretically grounded, 2) cross-domain, and 3) encompass cumulative protection and risk. In understanding profiles of risk and protection, we can inform evidence-based early interventions that address: 1) high-risk children, 2) the full range of risks, 3) vulnerable domains, and 4) protective factors.
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Cites
Anda, R. F., Felitti, V. J., Bremner, J. D., Walker, J. D., Whitfield, C., Perry, B. D., Dube, S. R., & Giles, W. H. (2006) · European archives of psychiatry and clinical neuroscience · doi:10.1007/s00406-005-0624-4 · Cited by 4,292 · see citing works
Childhood adversities and adult psychopathology in the WHO World Mental Health Surveys
Kessler, R. C., McLaughlin, K. A., Green, J. G., Gruber, M. J., Sampson, N. A., Zaslavsky, A. M., Aguilar-Gaxiola, S., Alhamzawi, A. O., Alonso, J., Angermeyer, M., et al. (2010) · British Journal of Psychiatry · doi:10.1192/bjp.bp.110.080499 · Cited by 2,640 · see citing works
Goodman, S. H., & Gotlib, I. H. (1999) · Psychological Review · doi:10.1037/0033-295x.106.3.458 · Cited by 2,493 · see citing works
The environment of childhood poverty
Evans, G. W. (2004) · American Psychologist · doi:10.1037/0003-066x.59.2.77 · Cited by 2,396 · see citing works
Cumulative risk and child development.
Evans, G. W., Li, D., & Whipple, S. S. (2013) · Psychological Bulletin · doi:10.1037/a0031808 · Cited by 2,024 · see citing works
Protective factors in children's responses to stress and disadvantage.
Rutter, M. L. (1979) · PubMed · Cited by 1,507 · see citing works
Childhood adversity and adult psychiatric disorder in the US National Comorbidity Survey
KESSLER, R. C., DAVIS, C. G., & KENDLER, K. S. (1997) · Psychological Medicine · doi:10.1017/s0033291797005588 · Cited by 1,298 · see citing works
When more is not better: the role of cumulative risk in child behavior outcomes
Carmody, K. A., Egeland, B. R., van Dulmen, M. H. M., & Sroufe, L. A. (2004) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2004.00351.x · Cited by 1,144 · see citing works
Managing to Make It: Urban Families and Adolescent Success
Furstenberg, F. F., & Ardelt, M. (1999) · Medical Entomology and Zoology · Cited by 914 · see citing works
STRESS, COPING AND DEVELOPMENT: SOME ISSUES AND SOME QUESTIONS *
Rutter, M. L. (1981) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.1981.tb00560.x · Cited by 850 · see citing works
Gutman, L. M., Sameroff, A. J., & Cole, R. (2003) · Developmental Psychology · doi:10.1037/0012-1649.39.4.777 · Cited by 445 · see citing works
Risk and protection: Are both necessary to understand diverse behavioral outcomes in adolescence?
Pollard, J. A., Hawkins, J. D., & Arthur, M. W. (1999) · Social Work Research · doi:10.1093/swr/23.3.145 · Cited by 393 · see citing works
Handbook of infant, toddler, and preschool mental health assessment.
DelCarmen‐Wiggins, R., & Carter, A. S. (2004) · Cited by 388 · see citing works
Children Who Prosper in Unfavorable Environments: The Relationship to Social Capital
Runyan, D. K., Hunter, W. M., Socolar, R. R. S., Amaya-Jackson, L. M., English, D., Landsverk, J. A., Dubowitz, H., Browne, D. H., Bangdiwala, S. I., & Mathew, R. M. (1998) · PEDIATRICS · doi:10.1542/peds.101.1.12 · Cited by 360 · see citing works
Families, Risk, and Competence
Dolgin, K. G., Lewis, M., & Feiring, C. (1999) · Journal of Marriage and the Family · doi:10.2307/354033 · Cited by 307 · see citing works
Family and Social Influences on the Development of Child Competence
Samerojf, A. J., Bartko, W. T., Baldwin, A. L., Baldwin, C., & Seifer, R. (2014) · Routledge eBooks · doi:10.4324/9781315805863-15 · Cited by 297 · see citing works
Hosman, C. M. H., van Doesum, K. T. M., & van Santvoort, F. (2009) · Advances in Mental Health · doi:10.5172/jamh.8.3.250 · Cited by 272 · see citing works
Family Socioeconomic Status and Consistent Environmental Stimulation in Early Childhood
Crosnoe, R., Leventhal, T., Wirth, R. J., Pierce, K. M., Pianta, R. C., & NICHD Early Child Care Research Network (2010) · Child Development · doi:10.1111/j.1467-8624.2010.01446.x · Cited by 255 · see citing works
Ostaszewski, K., & Zimmerman, M. A. (2006) · American Journal of Community Psychology · doi:10.1007/s10464-006-9076-x · Cited by 236 · see citing works
Psychosocial Constraints on the Development of Resilience
Sameroff, A. J., & Rosenblum, K. L. (2006) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1376.010 · Cited by 217 · see citing works
Children of Mothers with Serious Substance Abuse Problems: An Accumulation of Risks
Edge, N. A. C., Bradley, R. H., Mansell, L. W., Liu, J. Y., Roberts, T. J., Burgdorf, K., & Herrell, J. M. (2004) · The American Journal of Drug and Alcohol Abuse · doi:10.1081/ada-120029867 · Cited by 211 · see citing works
Violence exposure across multiple contexts: Individual and joint effects on adjustment.
Mrug, S., Loosier, P. S., & Windle, M. T. (2008) · American Journal of Orthopsychiatry · doi:10.1037/0002-9432.78.1.70 · Cited by 200 · see citing works
Madigan, S. L., Wade, M., Plamondon, A., Maguire, J. L., & Jenkins, J. M. (2017) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2017.04.052 · Cited by 163 · see citing works
Prenatal Drug Exposure: Infant and Toddler Outcomes
Bandstra, E. S., Morrow, C. E., Mansoor, E., & Accornero, V. H. (2010) · Journal of Addictive Diseases · doi:10.1080/10550881003684871 · Cited by 161 · see citing works
Brennan, P. A., Hall, J., Bor, W., Najman, J. M., & Williams, G. M. (2003) · Developmental Psychology · doi:10.1037/0012-1649.39.2.309 · Cited by 115 · see citing works
Identifying Risk and Protective Factors for Healthy Child Development
Sameroff, A. J. (2006) · Cambridge University Press eBooks · doi:10.1017/cbo9780511616259.004 · Cited by 105 · see citing works
Hooper, S. R., Burchinal, M., Roberts, J. E., Zeisel, S. A., & Neebe, E. C. (1998) · Journal of Applied Developmental Psychology · doi:10.1016/s0193-3973(99)80029-x · Cited by 92 · see citing works
An ecological perspective on cumulative school and neighborhood risk factors related to achievement
Whipple, S. S., Evans, G. W., Barry, R. L., & Maxwell, L. E. (2010) · Journal of Applied Developmental Psychology · doi:10.1016/j.appdev.2010.07.002 · Cited by 78 · see citing works
van Doesum, K. T. M., & Hosman, C. M. H. (2009) · Advances in Mental Health · doi:10.5172/jamh.8.3.264 · Cited by 68 · see citing works
Families count: effects on child and adolescent development
(2006) · Choice Reviews Online · doi:10.5860/choice.44-1810 · Cited by 65 · see citing works
Carta, J. J., Atwater, J. B., Greenwood, C. R., McConnell, S. R., McEvoy, M. A., & Williams, R. (2001) · Journal of Clinical Child & Adolescent Psychology · doi:10.1207/s15374424jccp3003_5 · Cited by 62 · see citing works
Lima, J. C., Caughy, M. O., Nettles, S. M., & O'Campo, P. J. (2010) · Social Science & Medicine · doi:10.1016/j.socscimed.2010.06.022 · Cited by 60 · see citing works
Andrews, N. C. Z., Motz, M., Pepler, D. J., Jeong, J. J., & Khoury, J. E. (2018) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2018.06.011 · Cited by 55 · see citing works
Self-citationCrafting identities and accessing opportunities post-Brown.
Spencer, M. B. (2005) · American Psychologist · doi:10.1037/0003-066x.60.8.821 · Cited by 50 · see citing works
Ackerman, B. P., Schoff, K. M., Levinson, K. L., et al. (1999) · Developmental Psychology · doi:10.1037/0012-1649.35.6.1355 · Cited by 49 · see citing works
Lamela, D. J. P. D. V., & Figueiredo, B. (2015) · Journal of Interpersonal Violence · doi:10.1177/0886260515615142 · Cited by 45 · see citing works
Espinet, S. D., Motz, M., Jeong, J. J., Jenkins, J. M., & Pepler, D. J. (2016) · Addiction Research & Theory · doi:10.3109/16066359.2016.1140148 · Cited by 36 · see citing works
Self-citationMaternal Substance Use and Neonatal Abstinence Syndrome: A Descriptive Study
McQueen, K., Murphy-Oikonen, J., & Desaulniers, L. (2015) · Maternal and Child Health Journal · doi:10.1007/s10995-015-1689-y · Cited by 27 · see citing works
Prenatal Maternal Substance Use and Offspring Outcomes
Huizink, A. C. (2015) · European Psychologist · doi:10.1027/1016-9040/a000197 · Cited by 17 · see citing works
Stover, D. (2015) · Scientific American · doi:10.1038/scientificamericansecrets0315-1 · Cited by 14 · see citing works
Mothander, P. R. (2016) · Infant Mental Health Journal · doi:10.1002/imhj.21593 · Cited by 9 · see citing works
Bondi, B. C., Pepler, D. J., Motz, M., & Andrews, N. C. Z. (2021) · Developmental Neuropsychology · doi:10.1080/87565641.2021.1986044 · Cited by 8 · see citing works
Self-citationStepping sideways to move forward: Closing the science–practice gap.
Pepler, D. J. (2016) · Canadian Psychology/Psychologie canadienne · doi:10.1037/cap0000046 · Cited by 7 · see citing works
Self-citationCumulative risk and protection measures data
Bondi, B. C., Pepler, D. J., Motz, M., et al. (2020) · Data in Brief · doi:10.1016/j.dib.2020.106129 · Cited by 6 · see citing works
Self-citationBondi, B. C., Pepler, D. J., Motz, M., et al. (2021) · Evidence-Based Practice in Child and Adolescent Mental Health · doi:10.1080/23794925.2020.1855612 · Cited by 2 · see citing works
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Howard, A. H., Roberts, M., Mitchell, T., & Wilke, N. G. (2023) · Adversity and Resilience Science · doi:10.1007/s42844-023-00088-y · Cited by 50 · see citing works
- Authors
- Bondi, B. C., Pepler, D. J., Motz, M., & Andrews, N. C. Z.
- Affiliations
- York University (CA)
- Brock University (CA)
- Corresponding author
- Bondi, Bianca C.
- Venue
- Child Abuse & Neglect
- Publisher
- Elsevier BV
- Published
- 2020-10
- Volume
- 108
- Pages
- 104631
- ISSN
- 0145-2134 (ISSN-L)
- OpenAlex
- W3046894890
- Cited by
- 13
- References
- 45
- Citations by year
- 2025: 4 · 2024: 3 · 2023: 1 · 2022: 1 · 2021: 3 · 2020: 1
- FWCI
- 1.45
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Child Abuse & Neglect (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Canadian Institutes of Health Research
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Prenatal Substance Exposure Effects
- Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
- Social Sciences › Safety Research › Child Welfare and Adoption
- Keywords
- prenatal drug exposure, cumulative risk, protective factors, sibling groups, child abuse prevention, early intervention, neurodevelopmental deficits
- MeSH terms
- Adult, Child, Child, Preschool, Female, Humans, Infant, Infant, Newborn, Male, Mothers, Parent-Child Relations, Pregnancy, Prenatal Exposure Delayed Effects, Retrospective Studies, Risk Factors, Siblings
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