The DOI matches its Crossref record; 110 of the 110 references it cites were found in a registry or an index.
Bacteriophages of the Human Gut: The “Known Unknown” of the Microbiome
Open accessAbstract
The human gut microbiome is a dense and taxonomically diverse consortium of microorganisms. While the bacterial components of the microbiome have received considerable attention, comparatively little is known about the composition and physiological significance of human gut-associated bacteriophage populations (phageome). By extrapolating our knowledge of phage-host interactions from other environments, one could expect that >1012 viruses reside in the human gut, and we can predict that they play important roles in regulating the complex microbial networks operating in this habitat. Before delving into their function, we need to first overcome the challenges associated with studying and characterizing the phageome. In this Review, we summarize the available methods and main findings regarding taxonomic composition, community structure, and population dynamics in the human gut phageome. We also discuss the main challenges in the field and identify promising avenues for future research.
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Cites
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Cited by
Cryan, J. F., O'Riordan, K. J., Cowan, C. S. M., Sandhu, K. V., Bastiaanssen, T. F. S., Boehme, M., Codagnone, M. G., Cussotto, S., Fulling, C., Golubeva, A. V., et al. (2019) · Physiological Reviews · doi:10.1152/physrev.00018.2018 · Cited by 5,286
CheckV assesses the quality and completeness of metagenome-assembled viral genomes
Nayfach, S., Camargo, A. P., Schulz, F., Eloe-Fadrosh, E., Roux, S., & Kyrpides, N. C. (2021) · Nature Biotechnology · doi:10.1038/s41587-020-00774-7 · Cited by 1,750
The Human Gut Virome Is Highly Diverse, Stable, and Individual Specific
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Self-citationGut microbiota in colorectal cancer development and therapy
Wong, C. C., & Yu, J. (2023) · Nature Reviews Clinical Oncology · doi:10.1038/s41571-023-00766-x · Cited by 721
The Gut Virome Database Reveals Age-Dependent Patterns of Virome Diversity in the Human Gut
Gregory, A. C., Zablocki, O., Zayed, A. A., Howell, A., Bolduc, B., & Sullivan, M. B. (2020) · Cell Host & Microbe · doi:10.1016/j.chom.2020.08.003 · Cited by 658
Metadata
- Authors
- Shkoporov, A. N., & Hill, C.
- Venue
- Cell Host & Microbe
- Publisher
- Elsevier BV
- Published
- 2019-02
- Volume
- 25
- Issue
- 2
- Pages
- 195-209
- ISSN
- 1931-3128 (ISSN-L)
- OpenAlex
- W2913714888
- Cited by
- 767
- References
- 110
- FWCI
- 43.65
- Type
- journal article
- Language
- en
- Open access
- bronze
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