The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
The Skin Microbiota: Balancing Risk and Reward
Open accessAbstract
The skin microbiome is an ecosystem comprised of a multitude of microbial species interacting with their surroundings, including other microbes and host epithelial and immune cells. These interactions are the basis of important roles within the skin microbiome that provide benefit to the host, boosting multiple aspects of barrier function, a critical function of this essential organ. However, with reward always comes risk; resident skin microbes function in a context-dependent manner, set on the backdrop of a dynamic host and microbial milieu. Here, we discuss the reward of hosting a microbial ecosystem on the skin, including protection from pathogens and tuning of the skin microenvironment. We also give consideration to how these skin residents, often termed “commensals” can cause disorder, damage, and promote skin disease.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Structure, function and diversity of the healthy human microbiome
The Human Microbiome Project Consortium (2012) · Nature · doi:10.1038/nature11234 · Cited by 11,726
Nasal Carriage as a Source of Staphylococcus aureus Bacteremia
von Eiff, C., Becker, K., Machka, K., Stammer, H., & Peters, G. (2001) · New England Journal of Medicine · doi:10.1056/nejm200101043440102 · Cited by 1,984
Topographic diversity of fungal and bacterial communities in human skin
NIH Intramural Sequencing Center Comparative Sequencing Program, Findley, K., Oh, J., Yang, J., Conlan, S., Deming, C., Meyer, J. A., Schoenfeld, D., Nomicos, E., Park, M., et al. (2013) · Nature · doi:10.1038/nature12171 · Cited by 1,206
Biogeography and individuality shape function in the human skin metagenome
Program, N. C. S., Oh, J., Byrd, A. L., Deming, C., Conlan, S., Kong, H. H., & Segre, J. A. (2014) · Nature · doi:10.1038/nature13786 · Cited by 1,148
Nakatsuji, T., Chen, T. H., Narala, S., Chun, K. A., Two, A. M., Yun, T., Shafiq, F., Kotol, P. F., Bouslimani, A., Melnik, A. V., et al. (2017) · Science Translational Medicine · doi:10.1126/scitranslmed.aah4680 · Cited by 1,095
Compartmentalized Control of Skin Immunity by Resident Commensals
Naik, S., Bouladoux, N., Wilhelm, C., Molloy, M. J., Salcedo, R., Kastenmuller, W., Deming, C., Quinones, M., Koo, L., Conlan, S., et al. (2012) · Science · doi:10.1126/science.1225152 · Cited by 1,092
Temporal Stability of the Human Skin Microbiome
Oh, J., Byrd, A. L., Park, M., Kong, H. H., & Segre, J. A. (2016) · Cell · doi:10.1016/j.cell.2016.04.008 · Cited by 1,036
Iwase, T., Uehara, Y., Shinji, H., Tajima, A., Seo, H., Takada, K., Agata, T., & Mizunoe, Y. (2010) · Nature · doi:10.1038/nature09074 · Cited by 991
Human commensals producing a novel antibiotic impair pathogen colonization
Zipperer, A., Konnerth, M. C., Laux, C., Berscheid, A., Janek, D., Weidenmaier, C., Burian, M., Schilling, N. A., Slavetinsky, C., Marschal, M., et al. (2016) · Nature · doi:10.1038/nature18634 · Cited by 938
Commensal–dendritic-cell interaction specifies a unique protective skin immune signature
Naik, S., Bouladoux, N., Linehan, J. L., Han, S.-J., Harrison, O. J., Wilhelm, C., Conlan, S., Himmelfarb, S., Byrd, A. L., Deming, C., et al. (2015) · Nature · doi:10.1038/nature14052 · Cited by 820
Cited by
Human Wound and Its Burden: Updated 2020 Compendium of Estimates
Sen, C. K. (2021) · Advances in Wound Care · doi:10.1089/wound.2021.0026 · Cited by 1,017
Next-generation sequencing: insights to advance clinical investigations of the microbiome
Wensel, C. R., Pluznick, J. L., Salzberg, S. L., & Sears, C. L. (2022) · Journal of Clinical Investigation · doi:10.1172/jci154944 · Cited by 437
Human Wound and Its Burden: Updated 2022 Compendium of Estimates
Sen, C. K. (2023) · Advances in Wound Care · doi:10.1089/wound.2023.0150 · Cited by 360
Sweat and Sebum Preferences of the Human Skin Microbiota
Swaney, M. H., Nelsen, A., Sandstrom, S., & Kalan, L. R. (2023) · Microbiology Spectrum · doi:10.1128/spectrum.04180-22 · Cited by 96
Skin Microbiome, Metabolome and Skin Phenome, from the Perspectives of Skin as an Ecosystem
Chen, H., Zhao, Q., Zhong, Q., Duan, C., Krutmann, J., Wang, J., & Xia, J. (2022) · Phenomics · doi:10.1007/s43657-022-00073-y · Cited by 79
Metadata
- Authors
- Flowers, L., & Grice, E. A.
- Venue
- Cell Host & Microbe
- Publisher
- Elsevier BV
- Published
- 2020-08
- Volume
- 28
- Issue
- 2
- Pages
- 190-200
- ISSN
- 1931-3128 (ISSN-L)
- OpenAlex
- W3048395252
- Cited by
- 276
- References
- 19
- FWCI
- 17.01
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: The Skin Microbiota: Balancing Risk and Reward. https://app.cochat.ai/papers/10.1016/j.chom.2020.06.017
- The paper
- Flowers, L., & Grice, E. A. (2020). The Skin Microbiota: Balancing Risk and Reward. Cell Host & Microbe. https://doi.org/10.1016/j.chom.2020.06.017
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.