Sample preparation
Abstract
A panorama of sample preparation methods has been composed from 481 references, with a highlight of some promising methods fast developed during recent years and a somewhat brief introduction on most of the well-developed methods. All the samples were commonly referred to molecular composition, being extendable to particles including cells but not to organs, tissues and larger bodies. Some criteria to evaluate or validate a sample preparation method were proposed for reference. Strategy for integration of several methods to prepare complicated protein samples for proteomic studies was illustrated and discussed.
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The limitation of highly sensitive analytical techniques has increased the need for a preliminary step for analyte enrichment prior to determination.
“The limitation of highly sensitive analytical techniques [1,2] has increased the need to a preliminary step for analytes enrichment prior to their determination [3].”
From Deep eutectic solvent as a novel disperser in dispersive liquid-liquid microextraction based on solidification of floating organic droplet (DLLME-SFOD) for preconcentration of steroids in water samples: Assessment of the method deleterious impact on the environment using Analytical Eco-Scale and Green Analytical Procedure Index (2019) · cites this paper as [3]
Sample preparation is the major bottleneck and a greater time-consuming step in developing an analytical method.
“Despite unimpeachable improvements in analytical instrumentation, sample preparation still represents the major bottleneck and a greater time-consuming step in developing an analytical method [1].”
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El-Deen, A. K., & Shimizu, K. (2019) · Microchemical Journal · doi:10.1016/j.microc.2019.103988 · Cited by 92 · see citing works
Farajzadeh, M. A., Djozan, D., & Khorram, P. (2012) · Analytica Chimica Acta · doi:10.1016/j.aca.2011.11.030 · Cited by 89 · see citing works
El-Deen, A. K., & Shimizu, K. (2021) · Molecules · doi:10.3390/molecules26237406 · Cited by 58 · see citing works
Li, F., Yu, Y., Zhang, H., Liu, T., Li, Y., & Duan, G. (2013) · Analytical Methods · doi:10.1039/c3ay40135a · Cited by 12 · see citing works
- Authors
- Chen, Y., Guo, Z., Wang, X., & Qiu, C.
- Affiliations
- Chinese Academy of Sciences (CN)
- Corresponding author
- Chen, Yi
- Venue
- Journal of Chromatography A
- Publisher
- Elsevier BV
- Published
- 2008-03
- Volume
- 1184
- Issue
- 1-2
- Pages
- 191-219
- ISSN
- 0021-9673 (ISSN-L)
- OpenAlex
- W4211084663
- Cited by
- 316
- References
- 457
- Citations by year
- 2026: 6 · 2025: 10 · 2024: 20 · 2023: 16 · 2022: 13 · 2021: 15 · 2020: 17 · 2019: 14 · 2018: 9 · 2017: 15 · 2016: 13 · 2015: 25 · 2014: 23 · 2013: 31 · 2012: 22
- FWCI
- 1.22
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Chromatography A (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Chemistry › Spectroscopy › Advanced Proteomics Techniques and Applications
- Physical Sciences › Chemistry › Analytical Chemistry › Analytical chemistry methods development
- Physical Sciences › Chemistry › Spectroscopy › Mass Spectrometry Techniques and Applications
- Keywords
- sample preparation, molecular composition, particles, cells, protein sample preparation, proteomics, methodological integration
- MeSH terms
- Adsorption, Chromatography, Gas, Electrophoresis, Filtration, Chemical Fractionation, Hydrogen-Ion Concentration, Isoelectric Focusing, Miniaturization, Pressure, Specimen Handling, Microdialysis, Chromatography, Supercritical Fluid, Ionic Liquids, Solid Phase Microextraction, Validation Studies as Topic
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