The DOI matches its Crossref record; 91 of the 91 references it cites were found in a registry or an index.
The innate immune response in ischemic acute kidney injury
Open accessAbstract
Kidney ischemia reperfusion injury is a major cause of morbidity in both allograft and native kidneys. Ischemia reperfusion-induced acute kidney injury is characterized by early, allo-antigen independent inflammation. Major components of the innate immune system are activated and participate in the pathogenesis of acute kidney injury, plus prime the allograft kidney for rejection. Soluble members of innate immunity implicated in acute kidney injury include the complement system, cytokines, and chemokines. Toll-like receptors (TLRs) are also important contributors. Effector cells that participate in ACUTE KIDNEY INJURY include the classic innate immune cells, neutrophils and macrophages. Recent data has unexpectedly identified lymphocytes as participants of early acute kidney injury responses. In this review, we will focus on immune mediators that participate in the pathogenesis of ischemic acute kidney injury.
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Self-citationPredominant role for C5b-9 in renal ischemia/reperfusion injury
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Targeted proximal tubule injury triggers interstitial fibrosis and glomerulosclerosis
Grgic, I., Campanholle, G., Bijol, V., Wang, C., Sabbisetti, V. S., Ichimura, T., Humphreys, B. D., & Bonventre, J. V. (2012) · Kidney International · doi:10.1038/ki.2012.20 · Cited by 477
Partners in crime: neutrophils and monocytes/macrophages in inflammation and disease
Prame Kumar, K., Nicholls, A. J., & Wong, C. H. Y. (2018) · Cell and Tissue Research · doi:10.1007/s00441-017-2753-2 · Cited by 417
Ischemia and Reperfusion Injury in Kidney Transplantation: Relevant Mechanisms in Injury and Repair
Nieuwenhuijs-Moeke, G. J., Pischke, S. E., Berger, S. P., Sanders, J. S. F., Pol, R. A., Struys, M. M. R. F., Ploeg, R. J., & Leuvenink, H. G. D. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9010253 · Cited by 328
Tumor-Induced NETosis as a Risk Factor for Metastasis and Organ Failure
Cedervall, J., Zhang, Y., & Olsson, A.-K. (2016) · Cancer Research · doi:10.1158/0008-5472.can-15-3051 · Cited by 146
Ischemia-reperfusion injury in kidney transplantation: mechanisms and potential therapeutic targets
Lasorsa, F., Rutigliano, M., Milella, M., d’Amati, A., Crocetto, F., Pandolfo, S. D., Barone, B., Ferro, M., Spilotros, M., Battaglia, M., et al. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25084332 · Cited by 74
Metadata
- Authors
- Jang, H. R., & Rabb, H.
- Venue
- Clinical Immunology
- Publisher
- Elsevier BV
- Published
- 2009-01
- Volume
- 130
- Issue
- 1
- Pages
- 41-50
- ISSN
- 1521-6616 (ISSN-L)
- OpenAlex
- W1964536962
- Cited by
- 358
- References
- 91
- FWCI
- 14.88
- Type
- journal article
- Language
- en
- Open access
- green
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