Nutrition and the deleterious side effects of nutritional supplements

Driscoll, Marcia S.; Kwon, Eun-Kyung M.; Skupsky, Hadas; Kwon, Soon-You; Grant-Kels, Jane M.

doi:10.1016/j.clindermatol.2010.03.023

Cited by 32Nutrition and Health StudiesTrace Elements in HealthComplementary and Alternative Medicine Studies

Nutrition and the deleterious side effects of nutritional supplements

Driscoll, Marcia S., Kwon, Eun-Kyung M., Skupsky, Hadas, Kwon, Soon-You, Grant-Kels, Jane M.·2010·Clinics in Dermatology

DOI 10.1016/j.clindermatol.2010.03.023

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Abstract

The potential adverse effects associated with some of the more common oral vitamin supplements--vitamins A, D, and E and niacin (forms include nicotinic acid and nicotinamide), and mineral supplements--zinc, copper, and iron, used in dermatology are manifold. Although the dermatologist may be familiar with adverse effects of vitamins A and D, less well-known adverse effects, such as hematologic and neurologic effects from zinc, are presented.

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Copper increases keratinocyte and fibroblast proliferation, facilitating skin rejuvenation, through its function in collagen formation.
“Through its significant function in collagen formation as a cofactor in enzymatic reactions during collagen crosslinking with lysyl oxidase, it increases keratinocyte and fibroblast proliferation, which facilitates skin rejuvenation.”
From AN OVERVIEW OF NEW TRENDS IN THE COSMETICS INDUSTRY (2025) · cites this paper as [57]

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Influential
Evaluation of Dietary Supplement Contamination by Xenobiotic and Essential Elements Using Microwave-Enhanced Sample Digestion and Inductively Coupled Plasma-Mass Spectrometry
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Nutritional Management of Menopausal Women
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Establishing biosynthetic pathways for the production of nicotinic acid and trigonelline in Escherichia coli
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Authors: Driscoll, M. S., Kwon, E.-K. M., Skupsky, H., Kwon, S.-Y., & Grant-Kels, J. M.
Affiliations: University of Maryland, Baltimore (US)
UConn Health (US)
Corresponding author: Driscoll, Marcia S.
ORCID: Grant-Kels, Jane M.
Venue: Clinics in Dermatology
Publisher: Elsevier BV
Published: 2010-07
Volume: 28
Issue: 4
Pages: 371-379
ISSN: 0738-081X (ISSN-L)
DOI: 10.1016/j.clindermatol.2010.03.023
OpenAlex: W2108445199
Cited by: 32
References: 130
Citations by year: 2026: 1 · 2025: 4 · 2024: 1 · 2023: 3 · 2022: 1 · 2021: 1 · 2020: 2 · 2019: 3 · 2018: 2 · 2017: 2 · 2016: 3 · 2015: 3 · 2014: 2 · 2013: 1
FWCI: 1.27
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Clinics in Dermatology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutrition and Health Studies
Health Sciences › Nursing › Nutrition and Dietetics › Trace Elements in Health
Health Sciences › Medicine › Complementary and alternative medicine › Complementary and Alternative Medicine Studies
Keywords: dietary supplements, adverse effects, vitamin A, vitamin D, vitamin E, nicotinic acid, nicotinamide, zinc, copper, iron, hematological effects, neurologic effects, dermatology
MeSH terms: Administration, Oral, Female, Humans, Male, Melanoma, Minerals, Nutritional Physiological Phenomena, Risk Factors, Sex Factors, Skin, Skin Neoplasms, Skin Physiological Phenomena, Vitamins, Randomized Controlled Trials as Topic, Dietary Supplements

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Nutrition and the deleterious side effects of nutritional supplements

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