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Radiation dose reduction in perfusion CT imaging of the brain using a 256-slice CT: 80 mAs versus 160 mAs
Abstract
Purpose To examine CTP of the brain in real patient data after reducing tube current down to 80 mAs to decrease radiation dose.Methods CTP was acquired in 60 suspected stroke patients with 80 (n: 30) or 160 (n: 30) mAs. Data were analyzed retrospectively by two independent readers. SNR, perfusion maps and image quality were compared in hypoperfused and non-affected areas.Results SNR was significantly higher in CTP with 160 mAs compared to 80 mAs (p < 0.001) in non-affected regions, but there was no significant difference in hypoperfused regions. Overall, images with 80 mAs were rated worse than the ones with 160 mAs (3.0 ± 0.7 versus 4.0 ± 0.7), however, still as sufficient to detect proximal vessel occlusions.Conclusion Tube current of 80 mAs is still sufficient for the detection of perfusion deficits of proximal vessel occlusions.
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Previous studies have only focused on controlling radiation exposure by techniques such as modifying tube voltage, tube current, and tube rotation time.
“However, previous studies have only focused on controlling radiation exposure by techniques, such as modifying the tube voltage, tube current, and tube rotation time [16,17].”
From A Novel Singular Value Decomposition-Based Denoising Method in 4-Dimensional Computed Tomography of the Brain in Stroke Patients with Statistical Evaluation (2020) · cites this paper as [17]
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Yang, W., Hong, J.-Y., Kim, J.-Y., Paik, S.-H., Lee, S. H., Park, J.-S., Lee, G., Kim, B. M., & Jung, Y.-J. (2020) · Sensors · doi:10.3390/s20113063 · Cited by 17
“However, previous studies have only focused on controlling radiation exposure by techniques, such as modifying the tube voltage, tube current, and tube rotation time [16,17].”
Background
Metadata
- Authors
- Riederer, I., Zimmer, C., Pfeiffer, D., Wunderlich, S., Poppert, H., Rummeny, E. J., & Huber, A.
- Affiliations
- TUM Klinikum (DE)
- Corresponding author
- Riederer, Isabelle
- ORCID
- Venue
- Clinical Imaging
- Publisher
- Elsevier BV
- Published
- 2018-07
- Volume
- 50
- Pages
- 188-193
- ISSN
- 0899-7071 (ISSN-L)
- OpenAlex
- W2802606979
- Cited by
- 12
- References
- 33
- Citations by year
- 2026: 1 · 2025: 1 · 2022: 1 · 2021: 4 · 2020: 3 · 2019: 2
- FWCI
- 1.55
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Clinical Imaging (publishedVersion)
- PubMed (publishedVersion)
- mediaTUM – the media and publications repository of the Technical University Munich (Technical University Munich) (submittedVersion)
- Topics
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Radiation Dose and Imaging
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced MRI Techniques and Applications
- Health Sciences › Medicine › Clinical Neurology › Acute Ischemic Stroke Management
- Keywords
- CT perfusion, brain perfusion imaging, radiation dose reduction, tube current, 256-slice CT, signal-to-noise ratio, image quality, hypoperfusion, stroke, cerebral perfusion deficits
- MeSH terms
- Adult, Aged, Aged, 80 and over, Blood Vessels, Brain, Female, Humans, Male, Middle Aged, Perfusion, Radiation Dosage, Radiographic Image Interpretation, Computer-Assisted, Retrospective Studies, Tomography, X-Ray Computed, Stroke
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