The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Therapeutical use of probiotic formulations in clinical practice
Open accessAbstract
Background & Aims The spreading of gastrointestinal diseases is growing all over the world. Although for some of them an effective therapeutic approach has been found, palliation rather than cure is very frequent due to a partial knowledge of their aethiology and pathogenesis. This review, analyzing the main clinical studies, aims at being a state of the art update of the use of probiotic formulations in daily practice. Methods In this review we include all the most significant clinical trials involving the use of probiotic formulations for the treatment of several pathologies. Results Dysbiosis has been observed in irritable bowel syndrome patients. Probiotics may exert a beneficial effect on Crohn’s disease affected patients who have shown gut microbiota antigens and altered wall permeability. Moreover some probiotic formulations seem to enhance the therapy for Helycobacter Pylori reducing its pathogenic potential. Intestinal ecology imbalance has been also linked to cancer induction, allergy, skin and urogenital diseases. In addition probiotics administration seems to be particularly useful to ease post-operative complications. Conclusion Further future clinical trials, involving large numbers of patients, will be mandatory to achieve definite evidence of the preventive and curative role of probiotics in medical practice.
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Cites
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Cited by
Intestinal microbiota in human health and disease: the impact of probiotics
Gerritsen, J., Smidt, H., Rijkers, G. T., & de Vos, W. M. (2011) · Genes & Nutrition · doi:10.1007/s12263-011-0229-7 · Cited by 724
Lyte, M. (2011) · BioEssays · doi:10.1002/bies.201100024 · Cited by 549
The role of lactobacilli and probiotics in maintaining vaginal health
Borges, S., Silva, J., & Teixeira, P. (2014) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-013-3064-9 · Cited by 397
The Battle of Probiotics and Their Derivatives Against Biofilms
Barzegari, A., Kheyrolahzadeh, K., Hosseiniyan Khatibi, S. M., Sharifi, S., Memar, M. Y., & Zununi Vahed, S. (2020) · Infection and Drug Resistance · doi:10.2147/idr.s232982 · Cited by 263
A comprehensive review of probiotics and human health-current prospective and applications
Sarita, B., Samadhan, D., Hassan, M. Z., & Kovaleva, E. G. (2025) · Frontiers in Microbiology · doi:10.3389/fmicb.2024.1487641 · Cited by 250
Metadata
- Authors
- Iannitti, T., & Palmieri, B.
- Venue
- Clinical Nutrition
- Publisher
- Elsevier BV
- Published
- 2010-12
- Volume
- 29
- Issue
- 6
- Pages
- 701-725
- ISSN
- 0261-5614 (ISSN-L)
- OpenAlex
- W2082707689
- Cited by
- 260
- References
- 19
- FWCI
- 26.96
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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