The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Dual regulation of the LDL receptor—Some clarity and new questions
Overview
The claims and statistics of this paper haven’t been checked yet.
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Integrity signals
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Claims the paper makes
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Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“Transcription of Ldlr is controlled by the sterol-responsive element binding protein 2 (Srebp2),12 while its turnover depends on proprotein convertase subtilisin/kexin type 9 (Pcsk9), a serine protease.13”
From The Sirt1 activator SRT3025 provides atheroprotection in Apoe−/− mice by reducing hepatic Pcsk9 secretion and enhancing Ldlr expression (2015) · cites this paper as [13]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Cohen, J., Pertsemlidis, A., Kotowski, I. K., Graham, R., Garcia, C. K., & Hobbs, H. H. (2005) · Nature Genetics · doi:10.1038/ng1509 · Cited by 1,381
Flagged first, then by citations
Research works printed but not linked: 9
- Abifadel, 2003, Nat. Genet., 34, 154, 10.1038/ng1161 · DOI · Paper page
- Benjannet, 2004, J. Biol. Chem., 279, 48865, 10.1074/jbc.M409699200 · DOI · Paper page
- Dubuc, 2004, Arterioscler. Thromb. Vasc. Biol., 24, 1454, 10.1161/01.ATV.0000134621.14315.43 · DOI · Paper page
- Maxwell, 2004, Proc. Natl. Acad. Sci. USA, 101, 7100, 10.1073/pnas.0402133101 · DOI · Paper page
- Maxwell, 2003, J. Lipid Res., 44, 2109, 10.1194/jlr.M300203-JLR200 · DOI · Paper page
- Park, 2004, J. Biol. Chem., 279, 50630, 10.1074/jbc.M410077200 · DOI · Paper page
- Rashid, 2005, Proc. Natl. Acad. Sci. USA, 102, 5374, 10.1073/pnas.0501652102 · DOI · Paper page
- Seidah, 2003, Proc. Natl. Acad. Sci. USA, 100, 928, 10.1073/pnas.0335507100 · DOI · Paper page
- Timms, 2004, Hum. Genet., 114, 349, 10.1007/s00439-003-1071-9 · DOI
Cited by
Sorted by citations
Guo, D., Reinitz, F., Youssef, M., Hong, C., Nathanson, D., Akhavan, D., Kuga, D., Amzajerdi, A. N., Soto, H., Zhu, S., et al. (2011) · Cancer Discovery · doi:10.1158/2159-8290.cd-11-0102 · Cited by 452
Targeting proprotein convertase subtilisin/kexin type 9 (PCSK9): From bench to bedside
Bao, X., Liang, Y., Chang, H., Cai, T., Feng, B., Gordon, K., Zhu, Y., Shi, H., He, Y., & Xie, L. (2024) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-023-01690-3 · Cited by 187
Miranda, M. X., van Tits, L. J., Lohmann, C., Arsiwala, T., Winnik, S., Tailleux, A., Stein, S., Gomes, A. P., Suri, V., Ellis, J. L., et al. (2015) · European Heart Journal · doi:10.1093/eurheartj/ehu095 · Cited by 153
Wadsack, C., Tabano, S., Maier, A., Hiden, U., Alvino, G., Cozzi, V., Hüttinger, M., Schneider, W. J., Lang, U., Cetin, I., et al. (2007) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00547.2005 · Cited by 93
Expanding biology of PCSK9: roles in atherosclerosis and beyond
Seidah, N. G., & Garçon, D. (2022) · Current Atherosclerosis Reports · doi:10.1007/s11883-022-01057-z · Cited by 76
Self-citation
Metadata
- Authors
- Attie, A. D., & Seidah, N. G.
- Venue
- Cell Metabolism
- Publisher
- Elsevier BV
- Published
- 2005-05
- Volume
- 1
- Issue
- 5
- Pages
- 290-292
- ISSN
- 1550-4131
- Cited by
- 83
- References
- 1
- Language
- en
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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