Metabolic Pitfalls of CNS Cre-Based Technology

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

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Generalized lacZ expression with the ROSA26 Cre reporter strain

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Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety

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Rapid, reversible activation of AgRP neurons drives feeding behavior in mice

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Genetic transformation of mouse embryos by microinjection of purified DNA.

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Behavioral phenotypes of inbred mouse strains: implications and recommendations for molecular studies

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Remote Control of Neuronal Activity in Transgenic Mice Expressing Evolved G Protein-Coupled Receptors

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Hypoxia-Inducible Factor 1α Induces Fibrosis and Insulin Resistance in White Adipose Tissue

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Talking about a Revolution

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Bacteriophage P1 site-specific recombination

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Nestin-expressing progenitor cells: function, identity and therapeutic implications

Bernal, A., & Arranz, L. (2018) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-018-2794-z · Cited by 415

A novel m6A reader Prrc2a controls oligodendroglial specification and myelination

Wu, R., Li, A., Sun, B., Sun, J.-G., Zhang, J., Zhang, T., Chen, Y., Xiao, Y., Gao, Y., Zhang, Q., et al. (2019) · Cell Research · doi:10.1038/s41422-018-0113-8 · Cited by 366

FGF21 Regulates Metabolism Through Adipose-Dependent and -Independent Mechanisms

BonDurant, L. D., Ameka, M., Naber, M. C., Markan, K. R., Idiga, S. O., Acevedo, M. R., Walsh, S. A., Ornitz, D. M., & Potthoff, M. J. (2017) · Cell Metabolism · doi:10.1016/j.cmet.2017.03.005 · Cited by 330

The glucose-dependent insulinotropic polypeptide (GIP) regulates body weight and food intake via CNS-GIPR signaling

Zhang, Q., Delessa, C. T., Augustin, R., Bakhti, M., Colldén, G., Drucker, D. J., Feuchtinger, A., Caceres, C. G., Grandl, G., Harger, A., et al. (2021) · Cell Metabolism · doi:10.1016/j.cmet.2021.01.015 · Cited by 322

Growth hormone regulates neuroendocrine responses to weight loss via AgRP neurons

Furigo, I. C., Teixeira, P. D. S., de Souza, G. O., Couto, G. C. L., Romero, G. G., Perelló, M., Frazão, R., Elias, L. L. K., Metzger, M., List, E. O., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-08607-1 · Cited by 230

Fibroblast Growth Factor 21: A Versatile Regulator of Metabolic Homeostasis

BonDurant, L. D., & Potthoff, M. J. (2018) · Annual Review of Nutrition · doi:10.1146/annurev-nutr-071816-064800 · Cited by 222

Nrf2 Protects Pancreatic β-Cells From Oxidative and Nitrosative Stress in Diabetic Model Mice

Yagishita, Y., Fukutomi, T., Sugawara, A., Kawamura, H., Takahashi, T., Pi, J., Uruno, A., & Yamamoto, M. P. (2013) · Diabetes · doi:10.2337/db13-0909 · Cited by 205

Pancreas-Specific Cre Driver Lines and Considerations for Their Prudent Use

Magnuson, M. A., & Osipovich, A. B. (2013) · Cell Metabolism · doi:10.1016/j.cmet.2013.06.011 · Cited by 182

Imbalanced Insulin Actions in Obesity and Type 2 Diabetes: Key Mouse Models of Insulin Signaling Pathway

Kubota, T., Kubota, N., & Kadowaki, T. (2017) · Cell Metabolism · doi:10.1016/j.cmet.2017.03.004 · Cited by 174

Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors

Luo, L., Ambrozkiewicz, M. C., Benseler, F., Chen, C., Dumontier, É., Falkner, S., Furlanis, E., Gomez, A. M., Hoshina, N., Huang, W., et al. (2020) · Neuron · doi:10.1016/j.neuron.2020.01.008 · Cited by 176

Impaired Islet Function in Commonly Used Transgenic Mouse Lines due to Human Growth Hormone Minigene Expression

Brouwers, B., de Faudeur, G., Osipovich, A. B., Goyvaerts, L., Lemaire, K., Boesmans, L., Cauwelier, E. J. G., Granvik, M., Pruniau, V. P. E. G., Lommel, L. V., et al. (2014) · Cell Metabolism · doi:10.1016/j.cmet.2014.11.004 · Cited by 149

Prolonged Cre expression driven by the α-myosin heavy chain promoter can be cardiotoxic

Pugach, E. K., Richmond, P. A., Azofeifa, J. G., Dowell, R. D., & Leinwand, L. A. (2015) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2015.06.019 · Cited by 119

Autophagy Ablation in Adipocytes Induces Insulin Resistance and Reveals Roles for Lipid Peroxide and Nrf2 Signaling in Adipose-Liver Crosstalk

Cai, J., Pires, K. M., Ferhat, M., Chaurasia, B., Buffolo, M. A., Smalling, R., Sargsyan, A., Atkinson, D. L., Summers, S. A., Graham, T. E., et al. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.10.040 · Cited by 107

Autophagy in Adipose Tissue Physiology and Pathophysiology

Ferhat, M., Funai, K., & Boudina, S. (2018) · Antioxidants and Redox Signaling · doi:10.1089/ars.2018.7626 · Cited by 106

Considerations and guidelines for mouse metabolic phenotyping in diabetes research

Alquier, T., & Poitout, V. (2017) · Diabetologia · doi:10.1007/s00125-017-4495-9 · Cited by 106

Inactivation of SOCS3 in leptin receptor-expressing cells protects mice from diet-induced insulin resistance but does not prevent obesity

Pedroso, J. A. B., Buonfiglio, D. D. C., Cardinali, L. I., Furigo, I. C., Ramos-Lobo, A. M., Tirapegui, J., Elias, C. F., & Donato, J. (2014) · Molecular Metabolism · doi:10.1016/j.molmet.2014.06.001 · Cited by 106

Behavioral phenotyping of Nestin-Cre mice: Implications for genetic mouse models of psychiatric disorders

Giusti, S. A., Vercelli, C. A., Vogl, A. M., Kolarz, A., Pino, N. S., Deussing, J. M., & Refojo, D. (2014) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2014.04.002 · Cited by 104

Liver Derived FGF21 Maintains Core Body Temperature During Acute Cold Exposure

Ameka, M., Markan, K. R., Morgan, D. A., BonDurant, L. D., Idiga, S. O., Naber, M. C., Zhu, Z., Zingman, L. V., Grobe, J. L., Rahmouni, K., et al. (2019) · Scientific Reports · doi:10.1038/s41598-018-37198-y · Cited by 93

Prolonged Period of Cortical Plasticity upon Redox Dysregulation in Fast-Spiking Interneurons

Morishita, H., Cabungcal, J.-H., Chen, Y., Do, K. Q., & Hensch, T. K. (2015) · Biological Psychiatry · doi:10.1016/j.biopsych.2014.12.026 · Cited by 92

Leptin-Responsive GABAergic Neurons Regulate Fertility through Pathways That Result in Reduced Kisspeptinergic Tone

Martin, C., Navarro, V. M., Simavlı, S. A., Vong, L., Carroll, R. S., Lowell, B. B., & Kaiser, U. B. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.3003-13.2014 · Cited by 90

Deficiency of Autophagy in Dendritic Cells Protects against Experimental Autoimmune Encephalomyelitis

Bhattacharya, A., Parillon, X., Zeng, S., Han, S., & Eissa, N. T. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.575860 · Cited by 87

Estrogen signaling in arcuate Kiss1 neurons suppresses a sex-dependent female circuit promoting dense strong bones

Herber, C. B., Krause, W. C., Wang, L., Bayrer, J. R., Li, A., Schmitz, M. T., Fields, A. J., Ford, B., Zhang, Z., Reid, M., et al. (2019) · Nature Communications · doi:10.1038/s41467-018-08046-4 · Cited by 86

Cre Recombinase

Duyne, G. D. V. (2015) · Microbiology Spectrum · doi:10.1128/microbiolspec.mdna3-0014-2014 · Cited by 84

Phenotypic Characterization of MIP-CreERT1Lphi Mice With Transgene-Driven Islet Expression of Human Growth Hormone

Oropeza, D., Jouvet, N., Budry, L., Campbell, J. E., Bouyakdan, K., Lacombe, J., Perron, G., Bergeron, V., Neuman, J. C., Brar, H. K., et al. (2015) · Diabetes · doi:10.2337/db15-0272 · Cited by 80

Deletion of Monoglyceride Lipase in Astrocytes Attenuates Lipopolysaccharide-induced Neuroinflammation

Grabner, G. F., Eichmann, T. O., Wagner, B., Gao, Y., Farzi, A., Taschler, U., Radner, F. P. W., Schweiger, M., Lass, A., Holzer, P. D., et al. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.683615 · Cited by 76

Metabolic and Behavioural Phenotypes in Nestin-Cre Mice Are Caused by Hypothalamic Expression of Human Growth Hormone

Declercq, J., Brouwers, B., Pruniau, V. P. E. G., Stijnen, P., de Faudeur, G., Tuand, K., Meulemans, S. M. P., Serneels, L., Schraenen, A., Schuit, F. C., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0135502 · Cited by 73

Molecular and Neural Functions of Rai1 , the Causal Gene for Smith-Magenis Syndrome

Huang, W., Guenthner, C. J., Xu, J., Nguyen, T., Schwarz, L. A., Wilkinson, A. W., Gozani, O., Chang, H. Y., Shamloo, M., & Luo, L. (2016) · Neuron · doi:10.1016/j.neuron.2016.09.019 · Cited by 74

Lost in translocation: the functions of the 18-kD translocator protein

Gut, P., Zweckstetter, M., & Banati, R. B. (2015) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2015.04.001 · Cited by 72

Fibroblast growth factor-21 controls dietary protein intake in male mice

Larson, K. R., Chaffin, A. T.-B., Goodson, M. L., Fang, Y., & Ryan, K. K. (2019) · Endocrinology · doi:10.1210/en.2018-01056 · Cited by 68

Neuronal systems and circuits involved in the control of food intake and adaptive thermogenesis

Caron, A., & Richard, D. (2016) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.13263 · Cited by 69

FGF21 resistance is not mediated by downregulation of beta-klotho expression in white adipose tissue

Markan, K. R., Naber, M. C., Small, S. M., Peltekian, L., Kessler, R. L., & Potthoff, M. J. (2017) · Molecular Metabolism · doi:10.1016/j.molmet.2017.03.009 · Cited by 70

New inducible genetic method reveals critical roles of GABA in the control of feeding and metabolism

Meng, F., Han, Y., Srisai, D., Белахов, В. В., Farías, M., Xu, Y., Palmiter, R. D., Baasov, T., & Wu, Q. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1602049113 · Cited by 66

Deletion of Neuronal GLT-1 in Mice Reveals Its Role in Synaptic Glutamate Homeostasis and Mitochondrial Function

McNair, L. F., Andersen, J. V., Aldana, B. I., Hohnholt, M. C., Nissen, J. D., Sun, Y., Fischer, K. D., Sonnewald, U., Nyberg, N. T., Webster, S. C., et al. (2019) · Journal of Neuroscience · doi:10.1523/jneurosci.0894-18.2019 · Cited by 64

Neuropathy target esterase (NTE/PNPLA6) and organophosphorus compound-induced delayed neurotoxicity (OPIDN)

Richardson, R. J., Fink, J. K., Glynn, P., Hufnagel, R. B., Махаева, Г. Ф., & Wijeyesakere, S. J. (2020) · Advances in neurotoxicology · doi:10.1016/bs.ant.2020.01.001 · Cited by 61

Endonucleases: new tools to edit the mouse genome

Wijshake, T., Baker, D. J., & van de Sluis, B. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2014.04.020 · Cited by 61

IL-12 sensing in neurons induces neuroprotective CNS tissue adaptation and attenuates neuroinflammation in mice

Andreadou, M., Ingelfinger, F., Feo, D. D., Cramer, T. L. M., Tuzlak, S., Friebel, E., Schreiner, B., Eede, P., Schneeberger, S., Geesdorf, M., et al. (2023) · Nature Neuroscience · doi:10.1038/s41593-023-01435-z · Cited by 56

Altered Baseline and Nicotine-Mediated Behavioral and Cholinergic Profiles in ChAT-Cre Mouse Lines

Chen, E., Lallai, V., Sherafat, Y., Grimes, N. P., Pushkin, A. N., Fowler, J., & Fowler, C. D. (2018) · Journal of Neuroscience · doi:10.1523/jneurosci.1433-17.2018 · Cited by 54

Learning improves decoding of odor identity with phase-referenced oscillations in the olfactory bulb

Losacco, J. T., Ramírez-Gordillo, D., Gilmer, J. I., & Restrepo, D. (2020) · eLife · doi:10.7554/elife.52583 · Cited by 50

Pancreatic PYY Is Critical in the Control of Insulin Secretion and Glucose Homeostasis in Female Mice

Shi, Y., Loh, K., Bensellam, M., Lee, K., Zhai, L., Lau, J., Cantley, J., Luzuriaga, J., Laybutt, D. R., & Herzog, H. (2015) · Endocrinology · doi:10.1210/en.2015-1168 · Cited by 50

Ablating astrocyte insulin receptors leads to delayed puberty and hypogonadism in mice

Manaserh, I. H., Chikkamenahalli, L. L., Ravi, S., Dube, P. R., Park, J. J., & Hill, J. W. (2019) · PLoS Biology · doi:10.1371/journal.pbio.3000189 · Cited by 50

Central growth hormone action regulates metabolism during pregnancy

Teixeira, P. D. S., Couto, G. C. L., Furigo, I. C., List, E. O., Kopchick, J. J., & Donato, J. (2019) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00229.2019 · Cited by 48

Generation and analysis of an improved Foxg1-IRES-Cre driver mouse line

Kawaguchi, D., Sahara, S., Zembrzycki, A., & O’Leary, D. D. M. (2016) · Developmental Biology · doi:10.1016/j.ydbio.2016.02.011 · Cited by 45

Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1

Rathjen, T., Yan, X., Kononenko, N. L., Ku, M., Song, K., Ferrarese, L., Tarallo, V., Puchkov, D., Kochlamazashvili, G., Brachs, S., et al. (2017) · Nature Neuroscience · doi:10.1038/nn.4590 · Cited by 45

Cre-dependent DNA recombination activates a STING-dependent innate immune response

Pépin, G., Ferrand, J., Höning, K., Jayasekara, W. S. N., Cain, J. E., Behlke, M. A., Gough, D. J., Williams, B. R. G., Hornung, V., & Gantier, M. P. (2016) · Nucleic Acids Research · doi:10.1093/nar/gkw405 · Cited by 48

Somatostatin-IRES-Cre Mice: Between Knockout and Wild-Type?

Viollet, C., Simon, A., Tolle, V., Labarthe, A., Grouselle, D., Loe-Mie, Y., Simonneau, M., Martel, G., & Epelbaum, J. (2017) · Frontiers in Endocrinology · doi:10.3389/fendo.2017.00131 · Cited by 48

ASIC1A in neurons is critical for fear‐related behaviors

Taugher, R. J., Lu, Y., Fan, R., Ghobbeh, A., Kreple, C. J., Faraci, F. M., & Wemmie, J. A. (2017) · Genes Brain & Behavior · doi:10.1111/gbb.12398 · Cited by 43

DNA methylation in AgRP neurons regulates voluntary exercise behavior in mice

MacKay, H., Scott, C. A., Duryea, J., Baker, M. S., Laritsky, E., Elson, A. E. T., Garland, T., Fiorotto, M. L., Chen, R., Li, Y., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-13339-3 · Cited by 44

Central FGF21 production regulates memory but not peripheral metabolism

Zhou, B., Claflin, K. E., Flippo, K. H., Sullivan, A. I., Asghari, A., Tadinada, S. M., Jensen-Cody, S. O., Abel, T. G., & Potthoff, M. J. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.111239 · Cited by 43

Mitochondrial Complex I Function Is Essential for Neural Stem/Progenitor Cells Proliferation and Differentiation

Cabello-Rivera, D., Sarmiento‐Soto, H., López‐Barneo, J., & Muñoz-Cabello, A. M. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00664 · Cited by 42

FoxO3 deficiency in cortical astrocytes leads to impaired lipid metabolism and aggravated amyloid pathology

Du, S., Jin, F., Maneix, L., Gedam, M., Xu, Y., Catic, A., Wang, M. C., & Zheng, H. (2021) · Aging Cell · doi:10.1111/acel.13432 · Cited by 43

Dnmt1, Dnmt3a and Dnmt3b cooperate in photoreceptor and outer plexiform layer development in the mammalian retina

Singh, R. K., Mallela, R. K., Moye, A. R., Dunham, N. R., Hedden, M., Enke, R. A., Fariss, R. N., Sternberg, H., West, M. D., & Nasonkin, I. O. (2016) · Experimental Eye Research · doi:10.1016/j.exer.2016.11.014 · Cited by 43

Neural-specific deletion of mitochondrial p32/C1qbp leads to leukoencephalopathy due to undifferentiated oligodendrocyte and axon degeneration

Yagi, M., Uchiumi, T., Sagata, N., Setoyama, D., Amamoto, R., Matsushima, Y., & Kang, D. (2017) · Scientific Reports · doi:10.1038/s41598-017-15414-5 · Cited by 41

STAT3 Regulates Mouse Neural Progenitor Proliferation and Differentiation by Promoting Mitochondrial Metabolism

Su, Y., Zhang, W., Patro, C. P. K., Zhao, J., Mu, T., Ma, Z., Xu, J., Ban, K. H.-K., Yi, C., & Zhou, Y. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00362 · Cited by 41

Brain JNK and metabolic disease

Nogueiras, R., & Sabio, G. (2020) · Diabetologia · doi:10.1007/s00125-020-05327-w · Cited by 42

Neuronal Loss of the Glutamate Transporter GLT-1 Promotes Excitotoxic Injury in the Hippocampus

Rimmele, T. S., Li, S., Andersen, J. V., Westi, E. W., Rotenberg, A., Wang, J., Aldana, B. I., Selkoe, D. J., Aoki, C. J., Dulla, C. G., et al. (2021) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2021.788262 · Cited by 41

Translational switching of Cry1 protein expression confers reversible control of circadian behavior in arrhythmic Cry-deficient mice

Maywood, E. S., Elliott, T. S., Patton, A. P., Krogager, T. P., Chesham, J. E., Ernst, R. J., Beránek, V., Brancaccio, M., Chin, J. W., & Hastings, M. H. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1811438115 · Cited by 37

Regulation of the gonadotropin‐releasing hormone neuron during stress

McCosh, R. B., O’Byrne, K. T., Karsch, F. J., & Breen, K. M. (2022) · Journal of Neuroendocrinology · doi:10.1111/jne.13098 · Cited by 35

Hemizygous Le-Cre Transgenic Mice Have Severe Eye Abnormalities on Some Genetic Backgrounds in the Absence of LoxP Sites

Dorà, N. J., Collinson, J. M., Hill, R. E., & West, J. D. (2014) · PLoS ONE · doi:10.1371/journal.pone.0109193 · Cited by 34

Adipocyte Gs but not Gi signaling regulates whole-body glucose homeostasis

Caron, A., Reynolds, R. P., Castorena, C. M., Michael, N. J., Lee, C. E., Lee, S., Berdeaux, R., Scherer, P. E., & Elmquist, J. K. (2019) · Molecular Metabolism · doi:10.1016/j.molmet.2019.06.019 · Cited by 34

Deletion of the clock gene Period2 (Per2) in glial cells alters mood-related behavior in mice

Martini, T., Ripperger, J. A., Stalin, J., Kores, A., Stumpe, M., & Albrecht, U. (2021) · Scientific Reports · doi:10.1038/s41598-021-91770-7 · Cited by 32

Glutamate Dehydrogenase Is Important for Ammonia Fixation and Amino Acid Homeostasis in Brain During Hyperammonemia

Voss, C. M., Arildsen, L., Nissen, J. D., Waagepetersen, H. S., Schousboe, A., Maechler, P., Ott, P., Vilstrup, H., & Walls, A. B. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.646291 · Cited by 34

Neuronal deficiency ofARV1causes an autosomal recessive epileptic encephalopathy

Palmer, E. E., Jarrett, K. E., Sachdev, R., Alzahrani, F., Hashem, M. O., Ibrahim, N., Sampaio, H. A., Kandula, T., Macintosh, R., Gupta, R., et al. (2016) · Human Molecular Genetics · doi:10.1093/hmg/ddw157 · Cited by 32

Central growth hormone signaling is not required for the timing of puberty

Bohlen, T. M., Zampieri, T. T., Furigo, I. C., Teixeira, P. D. S., List, E. O., Kopchick, J. J., Donato, J., & Frazão, R. (2019) · Journal of Endocrinology · doi:10.1530/joe-19-0242 · Cited by 31

Androgen Action via the Androgen Receptor in Neurons Within the Brain Positively Regulates Muscle Mass in Male Mice

Davey, R. A., Clarke, M. V., Russell, P. K., Rana, K., Seto, J. T., Roeszler, K. N., How, J. M. Y., Chia, L. Y., North, K. N., & Zajac, J. D. (2017) · Endocrinology · doi:10.1210/en.2017-00470 · Cited by 31

Rodent Models for the Analysis of Tissue Clock Function in Metabolic Rhythms Research

Tsang, A. H. K., Astiz, M., Leinweber, B., & Oster, H. (2017) · Frontiers in Endocrinology · doi:10.3389/fendo.2017.00027 · Cited by 30

The role of ARID1B, a BAF chromatin remodeling complex subunit, in neural development and behavior

Moffat, J. J., Jung, E., Ka, M., Smith, A. L., Jeon, B. T., Santen, G. W. E., & Kim, W.-Y. (2018) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2018.08.021 · Cited by 31

Germline recombination by conditional gene targeting with Parvalbumin-Cre lines

Kobayashi, Y., & Hensch, T. K. (2013) · Frontiers in Neural Circuits · doi:10.3389/fncir.2013.00168 · Cited by 36

Considerations for the use of Cre recombinase for conditional gene deletion in the mouse lens

Lam, P. T., Padula, S. L., Hoang, T. V., Poth, J. E., Liu, L., Liang, C., LeFever, A. S., Wallace, L. M., Ashery‐Padan, R., Riggs, P. K., et al. (2019) · Human Genomics · doi:10.1186/s40246-019-0192-8 · Cited by 30

The evolution of the axonal transport toolkit

Surana, S., Villarroel‐Campos, D., Lazo, O. M., Moretto, E., Tosolini, A. P., Rhymes, E. R., Richter, S., Sleigh, J. N., & Schiavo, G. (2019) · Traffic · doi:10.1111/tra.12710 · Cited by 31

Cell-specific and athero-protective roles for RIPK3 in a murine model of atherosclerosis

Colijn, S., Muthukumar, V., Xie, J., Gao, S., & Griffin, C. T. (2020) · Disease Models & Mechanisms · doi:10.1242/dmm.041962 · Cited by 29

Conditional Knockout of GLT-1 in Neurons Leads to Alterations in Aspartate Homeostasis and Synaptic Mitochondrial Metabolism in Striatum and Hippocampus

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11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) Inhibitors Still Improve Metabolic Phenotype in Male 11β-HSD1 Knockout Mice Suggesting Off-Target Mechanisms

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De Novo ARID1B mutations cause growth delay associated with aberrant Wnt/β–catenin signaling

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Increased GH Secretion and Body Growth in Mice Carrying Ablation of IGF-1 Receptor in GH-releasing Hormone Cells

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Podocyte-specific expression of Cre recombinase promotes glomerular basement membrane thickening

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NMDA receptor in vasopressin 1b neurons is not required for short-term social memory, object memory or aggression

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Inactive Atm abrogates DSB repair in mouse cerebellum more than does Atm loss, without causing a neurological phenotype

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Hypothalamic hormone-sensitive lipase regulates appetite and energy homeostasis

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Androgen and estrogen actions on male physical activity: a story beyond muscle

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A comparison of viral strategies and model systems to target norepinephrine neurons in the locus coeruleus reveals high variability in transgene expression patterns

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Melanocortin-3 receptors expressed in Nkx2.1(+ve) neurons are sufficient for controlling appetitive responses to hypocaloric conditioning

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Behavioral phenotyping and dopamine dynamics in mice with conditional deletion of the glutamate transporter GLT-1 in neurons: resistance to the acute locomotor effects of amphetamine

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Late neuroprogenitors contribute to normal retinal vascular development in a Hif2a-dependent manner

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Cre-Recombinase Dependent Germline Deletion of a Conditional Allele in the Rgs9cre Mouse Line

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Disordered autonomic function during exposure to moderate heat or exercise in a mouse model of Dravet syndrome

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Brain STAT5 modulates long-term metabolic and epigenetic changes induced by pregnancy and lactation in female mice.

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Molecular engineering tools for the development of vaccines against infectious diseases: current status and future directions

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A practical guide to genetic engineering of pancreatic β-cellsin vivo: Getting a grip on RIP and MIP

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Nestin-Cre Mouse Lines: A User Guide for CNS Genetics

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Pitfalls of PCR-Based Strategy for Genotyping Cre-Loxp Mice

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Pancreas-Specific Cre Driver Lines and Considerations for Their Prudent Use

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The Cre/Lox System to Assess the Development of the Mouse Brain.

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Tetracycline response element driven Cre causes ectopic recombinase activity independent of transactivator element

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