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FoxO1 Is Required for Most of the Metabolic and Hormonal Perturbations Produced by Hepatic Insulin Receptor Deletion in Male Mice

Ling, A. V., Gearing, M. E., Semova, I., Shin, D., Clements, R. L., Lai, Z. W., & Biddinger, S. B. (2017) · Endocrinology · doi:10.1210/en.2017-00870 · Cited by 30

Flavin-Containing Monooxygenase 3 Reduces Endoplasmic Reticulum Stress in Lipid-Treated Hepatocytes

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Gut microbiota and cardiovascular disease.

Witkowski, M., Weeks, T. L., & Hazen, S. L. (2020) · Circulation Research · doi:10.1161/circresaha.120.316242 · Cited by 1,051

NAFLD and increased risk of cardiovascular disease: clinical associations, pathophysiological mechanisms and pharmacological implications

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Gut microbiota-derived metabolites in the regulation of host immune responses and immune-related inflammatory diseases

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Role of the gut microbiota in type 2 diabetes and related diseases

Yang, G., Wei, J., Liu, P., Zhang, Q., Tian, Y., Hou, G., Meng, L., Xin, Y., & Jiang, X. (2021) · Metabolism · doi:10.1016/j.metabol.2021.154712 · Cited by 418

The microbial metabolite trimethylamine N-oxide promotes antitumor immunity in triple-negative breast cancer

Wang, H., Rong, X., Zhao, G., Zhou, Y., Xiao, Y., Ma, D., Jin, X., Wu, Y., Yan, Y., Yang, H., et al. (2022) · Cell Metabolism · doi:10.1016/j.cmet.2022.02.010 · Cited by 411

Abstract 14071: Gut Microbial Metabolite Trimethylamine N-oxide Enhances Endoplasmic Reticular Stress and Promotes Endothelial Dysfunction

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PERK specific inhibitor AMG-44 protects against Trimethylamine N-oxide (TMAO)-induced Endoplasmic Reticular Stress and Endothelial Dysfunction

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Trimethylamine N-Oxide: A Dual-function Compound at the Intersection of Gut Microbiota Metabolism and Systemic Disease

Alvi, A. D., Zhao, Y., Iqbal, Z., Abubakar, M., Afzal, M., & Habib, A. (2025) · Journal of Advances in Medical and Pharmaceutical Sciences · doi:10.9734/jamps/2025/v27i11825 · Cited by 1

Trimethylamine N-oxide promotes PERK-mediated endothelial-mesenchymal transition and apoptosis thereby aggravates atherosclerosis

Wang, B., Jun, Q., Bingyang, L., Xi, Y., Jianqing, Z., & Jiangfang, L. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.113209 · Cited by 24

Aorta- and liver-generated TMAO enhances trained immunity for increased inflammation via ER stress/mitochondrial ROS/glycolysis pathways

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