Balskus, Emily P.

Chemical transformation of xenobiotics by the human gut microbiota

Koppel, N., Maini Rekdal, V., & Balskus, E. P. (2017) · Science

Gut microbiota and healthPharmacogenetics and Drug Metabolism

Cited by 1,080

Discovery and inhibition of an interspecies gut bacterial pathway for Levodopa metabolism

Maini Rekdal, V., Bess, E. N., Bisanz, J. E., Turnbaugh, P. J., & Balskus, E. P. (2019) · Science

Parkinson's Disease Mechanisms and TreatmentsGut microbiota and health

Cited by 753

Predicting and Manipulating Cardiac Drug Inactivation by the Human Gut Bacterium Eggerthella lenta

Haiser, H. J., Gootenberg, D. B., Chatman, K., Sirasani, G., Balskus, E. P., & Turnbaugh, P. J. (2013) · Science

Pharmacogenetics and Drug MetabolismGut microbiota and health

Cited by 704

Microbial conversion of choline to trimethylamine requires a glycyl radical enzyme

Craciun, S., & Balskus, E. P. (2012) · Proceedings of the National Academy of Sciences

Microbial metabolism and enzyme functionAnaerobic Digestion and Biogas Production

Cited by 701

The Human Gut Bacterial Genotoxin Colibactin Alkylates DNA

Wilson, M. R., Jiang, Y., Villalta, P. W., Stornetta, A., Boudreau, P. D., Carrá, A., Brennan, C. A., Chun, E., Ngo, L., Samson, L. D., et al. (2019) · Science

Synthesis and pharmacology of benzodiazepine derivativesEscherichia coli research studies

Cited by 635

Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction

Chen, S., Henderson, A., Petriello, M. C., Romano, K. A., Gearing, M., Miao, J., Schell, M., Sandoval-Espinola, W. J., Tao, J., Sha, B., et al. (2019) · Cell Metabolism

Endoplasmic Reticulum Stress and DiseaseGut microbiota and health

Cited by 427

Characterization and Detection of a Widely Distributed Gene Cluster That Predicts Anaerobic Choline Utilization by Human Gut Bacteria

Martínez-del Campo, A., Bodea, S., Hamer, H. A., Marks, J. A., Haiser, H. J., Turnbaugh, P. J., & Balskus, E. P. (2015) · mBio

Gut microbiota and healthPolyamine Metabolism and Applications

Cited by 224

Metabolic, Epigenetic, and Transgenerational Effects of Gut Bacterial Choline Consumption

Romano, K. A., Martinez-del Campo, A., Kasahara, K., Chittim, C. L., Vivas, E. I., Amador-Noguez, D., Balskus, E. P., & Rey, F. E. (2017) · Cell Host & Microbe

Gut microbiota and healthEpigenetics and DNA Methylation

Cited by 224

Mechanistic insight into digoxin inactivation by Eggerthella lenta augments our understanding of its pharmacokinetics

Haiser, H. J., Seim, K. L., Balskus, E. P., & Turnbaugh, P. J. (2014) · Gut Microbes

Pharmacogenetics and Drug MetabolismGut microbiota and health

Cited by 197

Characterization of Choline Trimethylamine-Lyase Expands the Chemistry of Glycyl Radical Enzymes

Craciun, S., Marks, J. A., & Balskus, E. P. (2014) · ACS Chemical Biology

Microbial metabolism and enzyme functionMetal-Catalyzed Oxygenation Mechanisms

Cited by 139

Opportunities for merging chemical and biological synthesis

Wallace, S., & Balskus, E. P. (2014) · Current Opinion in Biotechnology

Enzyme Catalysis and ImmobilizationMicrobial Metabolic Engineering and Bioproduction

Cited by 86

Bacterial amylases enable glycogen degradation by the vaginal microbiome

Jenkins, D. J., Woolston, B. M., Hood-Pishchany, M. I., Pelayo, P., Konopaski, A. N., Quinn Peters, M., France, M. T., Ravel, J., Mitchell, C. M., Rakoff-Nahoum, S., et al. (2023) · Nature Microbiology

Reproductive tract infections researchGut microbiota and health

Cited by 63

Targeting the human gut microbiome with small-molecule inhibitors

Woo, A. Y. M., Aguilar Ramos, M. A., Narayan, R., Richards-Corke, K. C., Wang, M. L., Sandoval-Espinola, W. J., & Balskus, E. P. (2023) · Nature Reviews Chemistry

Gut microbiota and healthProbiotics and Fermented Foods

Cited by 42