Pentraxins as a key component of innate immunity

Interleukin-10 and the Interleukin-10 Receptor

Moore, K. W., de Waal Malefyt, R., Coffman, R. L., & O'Garra, A. (2001) · Annual Review of Immunology · doi:10.1146/annurev.immunol.19.1.683 · Cited by 6,737 · see citing works

The chemokine system in diverse forms of macrophage activation and polarization

MANTOVANI, A., SICA, A., SOZZANI, S., ALLAVENA, P., VECCHI, A., & LOCATI, M. (2004) · Trends in Immunology · doi:10.1016/j.it.2004.09.015 · Cited by 6,534 · see citing works

C-reactive protein: a critical update

Pepys, M. B., & Hirschfield, G. M. (2003) · Journal of Clinical Investigation · doi:10.1172/jci18921 · Cited by 4,576 · see citing works

C-reactive protein: a critical update

Pepys, M. B., & Hirschfield, G. M. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200318921 · Cited by 3,436 · see citing works

The acute phase response

Baumann, H., & Gauldie, J. (1994) · Immunology Today · doi:10.1016/0167-5699(94)90137-6 · Cited by 2,907 · see citing works

Acute phase proteins with special reference to C-reactive protein and related proteins (pentaxins) and serum amyloid A protein.

Pepys, M., & Baltz, M. (1983) · Advances in Immunology · doi:10.1016/s0065-2776(08)60379-x · Cited by 1,322 · see citing works

Pentraxins at the crossroads between innate immunity, inflammation, matrix deposition, and female fertility.

Garlanda, C., Bottazzi, B., Bastone, A., & Mantovani, A. (2005) · Annual Review of Immunology · doi:10.1146/annurev.immunol.23.021704.115756 · Cited by 885 · see citing works

C-Reactive Protein Binds to Apoptotic Cells, Protects the Cells from Assembly of the Terminal Complement Components, and Sustains an Antiinflammatory Innate Immune Response

Gershov, D., Kim, S., Brot, N., & Elkon, K. B. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.192.9.1353 · Cited by 695 · see citing works

Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune response

Garlanda, C., Hirsch, E., Bozza, S., Salustri, A., De Acetis, M., Nota, R., Maccagno, A., Riva, F., Bottazzi, B., Peri, G., et al. (2002) · Nature · doi:10.1038/nature01195 · Cited by 669 · see citing works

Shaping Gene Expression in Activated and Resting Primary Macrophages by IL-10

Lang, R., Patel, D. H., Morris, J. J., Rutschman, R. L., & Murray, P. J. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.169.5.2253 · Cited by 613 · see citing works

Reprogramming of the Macrophage Transcriptome in Response to Interferon-γ and Mycobacterium tuberculosis

Ehrt, S., Schnappinger, D., Bekiranov, S., Drenkow, J., Shi, S., Gingeras, T., Gaasterland, T., Schoolnik, G. K., & Nathan, C. (2001) · The Journal of Experimental Medicine · doi:10.1084/jem.194.8.1123 · Cited by 460 · see citing works

PTX3 plays a key role in the organization of the cumulus oophorus extracellular matrix and in in vivo fertilization

Salustri, A., Garlanda, C., Hirsch, E., Acetis, M. D., Maccagno, A., Bottazzi, B., Doni, A., Bastone, A., Mantovani, G., Beck‐Peccoz, P., et al. (2004) · Development · doi:10.1242/dev.01056 · Cited by 447 · see citing works

Prognostic Significance of the Long Pentraxin PTX3 in Acute Myocardial Infarction

Latini, R., Maggioni, A. P., Peri, G., Gonzini, L., Lucci, D., Mocarelli, P., Vago, L., Pasqualini, F., Signorini, S. G., Soldateschi, D., et al. (2004) · Circulation · doi:10.1161/01.cir.0000145167.30987.2e · Cited by 431 · see citing works

Interleukin-1-inducible genes in endothelial cells. Cloning of a new gene related to C-reactive protein and serum amyloid P component.

Breviario, F., D’Aniello, E., Golay, J., Peri, G., Bottazzi, B., Bairoch, A., Saccone, S., Marzella, R., Predazzi, V., & Rocchi, M. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)41653-5 · Cited by 416 · see citing works

Knockout of Pentraxin 3, a Downstream Target of Growth Differentiation Factor-9, Causes Female Subfertility

Varani, S., Elvin, J. A., Yan, C., et al. (2002) · Molecular Endocrinology · doi:10.1210/mend.16.6.0859 · Cited by 381 · see citing works

Multimer Formation and Ligand Recognition by the Long Pentraxin PTX3

Bottazzi, B., Vouret‐Craviari, V., Bastone, A., GIOIA, L. D., Matteucci, C., Peri, G., Spreafico, F., Pausa, M., D'Ettorre, C., Gianazza, E., et al. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.52.32817 · Cited by 378 · see citing works

Biochemical and functional characterization of the interaction between pentraxin 3 and C1q

Nauta, A. J., Bottazzi, B., Mantovani, A., Salvatori, G., Kishore, U., Schwaeble, W., Gingras, A. R., Tzima, S., Vivanco, F., Egido, J., et al. (2003) · European Journal of Immunology · doi:10.1002/immu.200310022 · Cited by 348 · see citing works

Circulating levels of the long pentraxin PTX3 correlate with severity of infection in critically ill patients

Müller-Stich, B. P., Peri, G., Doni, A., Torri, V., Landmann, R. M., Bottazzi, B., & Mantovani, A. (2001) · Critical Care Medicine · doi:10.1097/00003246-200107000-00017 · Cited by 327 · see citing works

The long pentraxin PTX3 binds to apoptotic cells and regulates their clearance by antigen-presenting dendritic cells

Rovere, P. Q., Peri, G., Fazzini, F., Bottazzi, B., Doni, A., Bondanza, A., Zimmermann, V. S., Garlanda, C., Fascio, U., Sabbadini, M. G., et al. (2000) · Blood · doi:10.1182/blood.v96.13.4300 · Cited by 326 · see citing works

Cutting Edge: Immune Stimulation by Neisserial Porins Is Toll-Like Receptor 2 and MyD88 Dependent

Massari, P., Henneke, P., Ho, Y., Latz, E., Golenbock, D. T., & Wetzler, L. M. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.168.4.1533 · Cited by 292 · see citing works

Production of the Long Pentraxin PTX3 in Advanced Atherosclerotic Plaques

Rolph, M. S., Zimmer, S., Bottazzi, B., et al. (2002) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000015595.95497.2f · Cited by 284 · see citing works

Complexity and Complementarity of Outer Membrane Protein A Recognition by Cellular and Humoral Innate Immunity Receptors

Jeannin, P., Bottazzi, B., Sironi, M., Doni, A., Rusnati, M., Presta, M., Maina, V., Magistrelli, G., Haeuw, J. F., Hoeffel, G., et al. (2005) · Immunity · doi:10.1016/j.immuni.2005.03.008 · Cited by 276 · see citing works

TSG-14, a tumor necrosis factor- and IL-1-inducible protein, is a novel member of the pentaxin family of acute phase proteins

Lee, G.-Y., Lee, T. H., & Vilček, J. (1993) · The Journal of Immunology · doi:10.4049/jimmunol.150.5.1804 · Cited by 247 · see citing works

IFN-γ-inducible protein 10 and pentraxin 3 plasma levels are tools for monitoring inflammation and disease activity in Mycobacterium tuberculosis infection

Azzurri, A., Sow, O. Y., Amedei, A., et al. (2004) · Microbes and Infection · doi:10.1016/j.micinf.2004.09.004 · Cited by 246 · see citing works

Recognition and clearance of apoptotic cells: a role for complement and pentraxins

Nauta, A. J., Daha, M. R., van Kooten, C., & Roos, A. (2003) · Trends in Immunology · doi:10.1016/s1471-4906(03)00030-9 · Cited by 231 · see citing works

OmpA targets dendritic cells, induces their maturation and delivers antigen into the MHC class I presentation pathway

Jeannin, P., Renno, T., Goetsch, L., et al. (2000) · Nature Immunology · doi:10.1038/82751 · Cited by 214 · see citing works

Cloning of mouse ptx3, a new member of the pentraxin gene family expressed at extrahepatic sites

Introna, M., Alles, V., Castellano, M., et al. (1996) · Blood · doi:10.1182/blood.v87.5.1862.1862 · Cited by 211 · see citing works

Increased mortality and inflammation in tumor necrosis factor-stimulated gene-14 transgenic mice after ischemia and reperfusion injury.

Souza, D. G., Soares, A. C., Pinho, V., Torloni, H., Reis, L., Martins, M. T., & Dias, A. A. (2002) · American Journal of Pathology · doi:10.1016/s0002-9440(10)61122-4 · Cited by 208 · see citing works

Transgenic human C-reactive protein is not proatherogenic in apolipoprotein E-deficient mice

Hirschfield, G. M., Gallimore, J. R., Kahan, M., Hutchinson, W. L., Sabin, C. A., Benson, G. M., Dhillon, A. P., Tennent, G. A., & Pepys, M. B. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0503202102 · Cited by 192 · see citing works

Selective recognition of fibroblast growth factor-2 by the long pentraxin PTX3 inhibits angiogenesis

Rusnati, M., Camozzi, M., Moroni, E., Bottazzi, B., Peri, G., Indraccolo, S., Amadori, A., Mantovani, A., & Presta, M. (2004) · Blood · doi:10.1182/blood-2003-10-3433 · Cited by 186 · see citing works

Expression and production of the long pentraxin PTX3 in rheumatoid arthritis (RA)

Luchetti, M. M., Piccinini, G., Mantovani, A., Peri, G., Matteucci, C., Pomponio, G., Fratini, M., Fraticelli, P., Sambo, P., Loreto, C. D., et al. (2000) · Clinical & Experimental Immunology · doi:10.1046/j.1365-2249.2000.01110.x · Cited by 180 · see citing works

Production of the soluble pattern recognition receptor PTX3 by myeloid, but not plasmacytoid, dendritic cells

Doni, A., Peri, G., Chieppa, M., Allavena, P., Pasqualini, F., Vago, L., Romani, L. R., Garlanda, C., & Mantovani, A. (2003) · European Journal of Immunology · doi:10.1002/eji.200324390 · Cited by 174 · see citing works

PTX3 function as an opsonin for the dectin-1-dependent internalization of zymosan by macrophages

Diniz, S. N., Nomizo, R., Cisalpino, P. S., Teixeira, M. M., Brown, G. D., Mantovani, A., Gordon, S., Reis, L. F. L., & Dias, A. A. M. (2004) · Journal of Leukocyte Biology · doi:10.1189/jlb.0803371 · Cited by 171 · see citing works

Modified atherogenic lipoproteins induce expression of pentraxin-3 by human vascular smooth muscle cells

Klouche, M., Peri, G., Knabbe, C., et al. (2004) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2004.03.020 · Cited by 156 · see citing works

Long Pentraxin PTX3 Upregulates Tissue Factor Expression in Human Endothelial Cells

Napoleone, E., Santo, A. D., Bastone, A., et al. (2002) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000012282.39306.64 · Cited by 152 · see citing works

DNA microarray analysis of gene expression in alveolar epithelial cells in response to TNFα, LPS, and cyclic stretch

dos Santos, C. C., Han, B., Andrade, C., Bai, X., Uhlig, S., Hubmayr, R. D., Tsang, M. E., Lodyga, M., Keshavjee, S. H., Slutsky, A. S., et al. (2004) · Physiological Genomics · doi:10.1152/physiolgenomics.00153.2004 · Cited by 145 · see citing works

Long pentraxins: an emerging group of proteins with diverse functions

Goodman, A. R., Cardozo, T. J., Abagyan, R. A., Altmeyer, A., Wisniewski, H., & Vilček, J. (1996) · Cytokine & Growth Factor Reviews · doi:10.1016/1359-6101(96)00019-6 · Cited by 137 · see citing works

Characterization of the long pentraxin PTX3 as a TNFα-induced secreted protein of adipose cells

Abderrahim-Ferkoune, A., Bézy, O., Chiellini, C., Maffei, M., Grimaldi, P. A., Bonino, F., Moustaïd‐Moussa, N., Pasqualini, F., Mantovani, A., Ailhaud, G. P., et al. (2003) · Journal of Lipid Research · doi:10.1194/jlr.m200382-jlr200 · Cited by 136 · see citing works

Anti- Aspergillus fumigatus Efficacy of Pentraxin 3 Alone and in Combination with Antifungals

Gaziano, R., Bozza, S., Bellocchio, S., Perruccio, K., Montagnoli, C., Pitzurra, L., Salvatori, G., Santis, R. D., Carminati, P., Mantovani, A., et al. (2004) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.48.11.4414-4421.2004 · Cited by 133 · see citing works

Human renal epithelial cells produce the long pentraxin PTX3

Nauta, A. J., de Haij, S., Bottazzi, B., et al. (2005) · Kidney International · doi:10.1111/j.1523-1755.2005.67111.x · Cited by 127 · see citing works

TSG-14 transgenic mice have improved survival to endotoxemia and to CLP-induced sepsis

Dias, A. A. M., Goodman, A. R., dos Santos, J. L., Gomes, R. N., Altmeyer, A., Bozza, P. T., Horta, M. F., Vilček, J., & Reis, L. F. L. (2001) · Journal of Leukocyte Biology · doi:10.1189/jlb.69.6.928 · Cited by 124 · see citing works

Chromatin-Independent Binding of Serum Amyloid P Component to Apoptotic Cells

Familian, A., Zwart, B., Huisman, H. G., Rensink, I., Roem, D., Hordijk, P. L., Aarden, L. A., & Hack, C. E. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.167.2.647 · Cited by 117 · see citing works

The long pentraxin PTX3 up-regulates tissue factor in activated monocytes: another link between inflammation and clotting activation

Napoleone, E., Santo, A. D., Peri, G., et al. (2004) · Journal of Leukocyte Biology · doi:10.1189/jlb.1003528 · Cited by 114 · see citing works

Elevated plasma levels of the long pentraxin, pentraxin 3, in severe dengue virus infections

Mairuhu, A. T. A., Peri, G., Setiati, T. E., Hack, C. E., Koraka, P., Soemantri, A., Osterhaus, A. D. M. E., Brandjes, D. P. M., van der Meer, J. W. M., Mantovani, A., et al. (2005) · Journal of Medical Virology · doi:10.1002/jmv.20397 · Cited by 111 · see citing works

Distinct Transcriptional Programs Activated by Interleukin-10 with or without Lipopolysaccharide in Dendritic Cells: Induction of the B Cell-Activating Chemokine, CXC Chemokine Ligand 13

Perrier, P., Martínez, F. O., Locati, M., Bianchi, G., Nebuloni, M., Vago, G. G., Bazzoni, F., Sozzani, S., Allavena, P., & Mantovani, A. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.172.11.7031 · Cited by 108 · see citing works

The pattern recognition receptor PTX3 is recruited at the synapse between dying and dendritic cells, and edits the cross-presentation of self, viral, and tumor antigens

Baruah, P., Propato, A., Dumitriu, I. E., Rovere, P. Q., Russo, V. E. A., Fontana, R., Accapezzato, D., Peri, G., Mantovani, A., Barnaba, V., et al. (2005) · Blood · doi:10.1182/blood-2005-03-1112 · Cited by 97 · see citing works

Dynamic induction of the long pentraxin PTX3 in the CNS after limbic seizures: evidence for a protective role in seizure-induced neurodegeneration

Ravizza, T., Moneta, D., Bottazzi, B., Peri, G., Garlanda, C., Hirsch, E., Richards, G. J., Mantovani, A., & Vezzani, A. (2001) · Neuroscience · doi:10.1016/s0306-4522(01)00177-4 · Cited by 83 · see citing works

Constitutive expression of Bcl-xL or Bcl-2 prevents peptide antigen-induced T cell deletion but does not influence T cell homeostasis after a viral infection

Petschner, F., Zimmermann, C., Strasser, A., Grillot, D., Núñez, G., & Pircher, H. (1998) · European Journal of Immunology · doi:10.1002/(sici)1521-4141(199802)28:02 · Cited by 77 · see citing works

Inducible expression of the long pentraxin PTX3 in the central nervous system

Polentarutti, N., Bottazzi, B., Santo, E. D., Blasi, E., Agnello, D., Ghezzi, P., Introna, M., Bartfai, T., Richards, G. J., & Mantovani, A. (2000) · Journal of Neuroimmunology · doi:10.1016/s0165-5728(00)00214-9 · Cited by 77 · see citing works

Knockout of Pentraxin 3, a Downstream Target of Growth Differentiation Factor-9, Causes Female Subfertility

Varani, S. (2002) · Molecular Endocrinology · doi:10.1210/me.16.6.1154 · Cited by 69 · see citing works

Differential regulation of TSG-14 expression in murine fibroblasts and peritoneal macrophages

Goodman, A. R., Levy, D. E., Reis, L. F. L., et al. (2000) · Journal of Leukocyte Biology · doi:10.1002/jlb.67.3.387 · Cited by 60 · see citing works

Human herpesvirus 8-derived viral IL-6 induces PTX3 expression in Kaposi's sarcoma cells

Klouche, M., Brockmeyer, N. H., Knabbe, C., & Rose‐John, S. (2002) · AIDS · doi:10.1097/00002030-200205240-00001 · Cited by 38 · see citing works

PTX3 gene expression in Castleman'sdisease

Malaguarnera, L., Pilastro, M. R., Vicari, L. O., et al. (2000) · European Journal Of Haematology · doi:10.1034/j.1600-0609.2000.9l071.x · Cited by 12 · see citing works

Untitled work

Komuro (2001) · doi:10.1002/1529-0131(200112)44:12

Adverse childhood experiences, allostasis, allostatic load and age-related disease

Danese, A., & McEwen, B. S. (2012) · Physiology & Behavior · doi:10.1016/j.physbeh.2011.08.019 · Cited by 2,140 · see citing works

Interferons: Signaling, antiviral and viral evasion

Bonjardim, C. A., Ferreira, P. C. P., & Kroon, E. G. (2009) · Immunology Letters · doi:10.1016/j.imlet.2008.11.002 · Cited by 196 · see citing works

A Combination of Neurofilament Light, Glial Fibrillary Acidic Protein, and Neuronal Pentraxin-2 Discriminates Between Frontotemporal Dementia and Other Dementias

Bolsewig, K., Hok-A-Hin, Y. S., Sepe, F. N., Boonkamp, L., Jacobs, D., Bellomo, G., Paoletti, F. P., Vanmechelen, E., Teunissen, C. E., Parnetti, L., et al. (2022) · Journal of Alzheimer's Disease · doi:10.3233/jad-220318 · Cited by 36 · see citing works

Heterocomplexes of Mannose-binding Lectin and the Pentraxins PTX3 or Serum Amyloid P Component Trigger Cross-activation of the Complement System

Ma, Y. J., Doni, A., Skjoedt, M., Honoré, C., Arendrup, M. C., Mantovani, A., & Garred, P. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.190637 · Cited by 117 · see citing works

The long pentraxin PTX3 in vascular pathology

Mantovani, A., Garlanda, C., Bottazzi, B., Peri, G., Doni, A., de la Torre, Y. M., & Latini, R. (2006) · Vascular Pharmacology · doi:10.1016/j.vph.2006.08.011 · Cited by 141 · see citing works

Biology of Human Pentraxin 3 (PTX3) in Acute and Chronic Kidney Disease

Speeckaert, M. M., Speeckaert, R., Carrero, J. J., Vanholder, R. C., & Delanghe, J. (2013) · Journal of Clinical Immunology · doi:10.1007/s10875-013-9879-0 · Cited by 40 · see citing works

The Long Pentraxin PTX3 as a Key Component of Humoral Innate Immunity and a Candidate Diagnostic for Inflammatory Diseases

Jaillon, S., Bonavita, E., Gentile, S., Rubino, M., Laface, I., Garlanda, C., & Mantovani, A. (2014) · International Archives of Allergy and Immunology · doi:10.1159/000368778 · Cited by 55 · see citing works

Pattern Recognition by Pentraxins

Agrawal, A., Singh, P. P., Bottazzi, B., Garlanda, C., & Mantovani, A. (2009) · Advances in Experimental Medicine and Biology · doi:10.1007/978-1-4419-0901-5_7 · Cited by 153 · see citing works