Automatic detection and measurement of nuchal translucency
Open accessAbstract
In this paper we propose a new methodology to support the physician both to identify automatically the nuchal region and to obtain a correct thickness measurement of the nuchal translucency. The thickness of the nuchal translucency is one of the main markers for screening of chromosomal defects such as trisomy 13, 18 and 21. Its measurement is performed during ultrasound scanning in the first trimester of pregnancy. The proposed methodology is mainly based on wavelet and multi resolution analysis. The performance of our method was analysed on 382 random frames, representing mid-sagittal sections, uniformly extracted from real clinical ultrasound videos of 12 patients. According to the ground-truth provided by an expert physician, we obtained a true positive rate equal to 99.95% with respect to the nuchal region detection and about 64% of measurements present an error equal to 1 pixel (which corresponds to 0.1mm), respectively.
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A potential benefit of first trimester AI models was a highly accurate non-invasive method for anomaly screening.
“The potential benefits of these models were the highly accurate non-invasive method for anomaly screening [134]”
From Evolving the Era of 5D Ultrasound? A Systematic Literature Review on the Applications for Artificial Intelligence Ultrasound Imaging in Obstetrics and Gynecology (2023) · cites this paper as [134]
The Abstract (p. 1) describes an automatic first-trimester ultrasound method for measuring nuchal translucency, a marker used to screen for chromosomal defects. The Conclusions (pp. 17–18) call ultrasound noninvasive and report high accuracy for locating the nuchal region, but the paper does not establish that the method itself is highly accurate at detecting fetal anomalies. (LLM, conf=0.88)
Experimental — accuracy not yet measuredWalker et al., Zhang et al., Sciortino et al., and Deng et al. introduced AI models for automated detection and measurement of NT.
“The research groups Walker et al. [132], Zhang et al. [133], Sciortino et al. [134], and Deng et al. [135] addressed the time consuming process of NT measurement by introducing AI models for its automated detection and measurement”
From Evolving the Era of 5D Ultrasound? A Systematic Literature Review on the Applications for Artificial Intelligence Ultrasound Imaging in Obstetrics and Gynecology (2023) · cites this paper as [134]
The Results and discussions section (p. 15) says Sciortino et al.’s methodology detects and measures nuchal translucency automatically. But the Wavelet image processing section (p. 8) describes a wavelet-based image-processing algorithm, not an AI model; that characterization is not supported by our copy. (LLM, conf=0.82)
Experimental — accuracy not yet measuredA limitation of first trimester AI models was missing real-time application for clinical applicability.
“and missing real-time application for clinical applicability [133,134,138].”
From Evolving the Era of 5D Ultrasound? A Systematic Literature Review on the Applications for Artificial Intelligence Ultrasound Imaging in Obstetrics and Gynecology (2023) · cites this paper as [134]
The Abstract (p. 1) and Dataset description (p. 7) describe testing on frames extracted from clinical ultrasound videos, but do not assess real-time operation or identify its absence as a limitation. The Conclusions (pp. 17–18) discuss clinical use without addressing whether the method runs in real time. Searches for real-time application and processing time found no decisive passage. (LLM, conf=0.72)
Experimental — accuracy not yet measured
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- Authors
- Sciortino, G., Tegolo, D., & Valenti, C.
- Affiliations
- University of Palermo (IT)
- Corresponding author
- Valenti, Cesare
- Venue
- Computers in Biology and Medicine
- Publisher
- Elsevier BV
- Published
- 2017-03
- Volume
- 82
- Pages
- 12-20
- ISSN
- 0010-4825 (ISSN-L)
- OpenAlex
- W2576014699
- Cited by
- 55
- References
- 27
- Citations by year
- 2026: 8 · 2025: 7 · 2024: 10 · 2023: 4 · 2022: 8 · 2021: 5 · 2020: 4 · 2019: 6 · 2018: 1 · 2017: 2
- FWCI
- 1.48
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- Locations
- Computers in Biology and Medicine (publishedVersion)
- PubMed (publishedVersion)
- Nova Science Publishers (Nova Science Publishers, Inc.) (submittedVersion, other-oa)
- Topics
- Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Medical Image Segmentation Techniques
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Prenatal Screening and Diagnostics
- Health Sciences › Health Professions › Health Information Management › Artificial Intelligence in Healthcare
- Keywords
- nuchal translucency, thickness measurement, first-trimester ultrasound, prenatal screening, chromosomal abnormalities, Down syndrome, trisomy 18, trisomy 13, wavelet analysis, multiresolution analysis
- MeSH terms
- Machine Learning, Algorithms, Down Syndrome, Humans, Image Interpretation, Computer-Assisted, Pattern Recognition, Automated, Sensitivity and Specificity, Reproducibility of Results, Nuchal Translucency Measurement, Wavelet Analysis
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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