WAVELET ANALYSIS AND NEURAL NETWORK CLASSIFIERS TO DETECT MID-SAGITTAL SECTIONS FOR NUCHAL TRANSLUCENCY MEASUREMENT
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We propose a methodology to support the physician in the automatic identification of mid-sagittal sections of the fetus in ultrasound videos acquired during the first trimester of pregnancy. A good mid-sagittal section is a key requirement to make the correct measurement of nuchal translucency which is one of the main marker for screening of chromosomal defects such as trisomy 13, 18 and 21. NT measurement is beyond the scope of this article. The proposed methodology is mainly based on wavelet analysis and neural network classifiers to detect the jawbone and on radial symmetry analysis to detect the choroid plexus. Those steps allow to identify the frames which represent correct mid-sagittal sections to be processed. The performance of the proposed methodology was analyzed on 3000 random frames uniformly extracted from 10 real clinical ultrasound videos. With respect to a ground-truth provided by an expert physician, we obtained a true positive, a true negative and a balanced accuracy equal to 87.26%, 94.98% and 91.12% respectively.
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Three studies focused on detection of the midsagittal plane of the fetus, with one study focusing on 2D ultrasound and two studies on 3D ultrasound.
“Three studies focused on the detection of the midsagittal plane of the fetus, with one study focusing on 2D ultrasound 19 and two studies on 3D ultrasound.20,21”
From Artificial intelligence in obstetric ultrasound: A scoping review. (2023) · cites this paper as [19]
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Snijders, R., Noble, P., Sebire, N., Souka, A., & Nicolaides, K. (1998) · The Lancet · doi:10.1016/s0140-6736(97)11280-6 · Cited by 1,572 · cited 1× · see citing works
“In the faraway years the FMF proposed a new methodology based on a combination of the measurement of the nuchal translucency and the maternal age to reduce the risk of trisomy 21 (Snijders et al., 1998).”
MethodImage processing with neural networks—a review
Egmont-Petersen, M., de Ridder, D., & Heinz Handels, A. (2002) · Pattern Recognition · doi:10.1016/s0031-3203(01)00178-9 · Cited by 1,185 · see citing works
Fast radial symmetry for detecting points of interest
Loy, G., & Zelinsky, A. (2003) · IEEE Transactions on Pattern Analysis and Machine Intelligence · doi:10.1109/tpami.2003.1217601 · Cited by 601 · see citing works
Context-free attentional operators: The generalized symmetry transform
Reisfeld, D., Wolfson, H. J., & Yeshurun, Y. (1995) · International Journal of Computer Vision · doi:10.1007/bf01418978 · Cited by 416 · see citing works
Wald, N., Rodeck, C. H., Hackshaw, A. K., Walters, J. C., Chitty, L. S., & Mackinson, A. (2003) · Journal of Medical Screening · doi:10.1258/096914103321824133 · Cited by 331 · see citing works
Hyett, J. A., Moscoso, G. J., Papapanagiotou, G., Perdu, M., & Nicolaides, K. H. (1996) · Ultrasound in Obstetrics and Gynecology · doi:10.1046/j.1469-0705.1996.07040245.x · Cited by 208 · see citing works
González-Audícana, M., Otazu, X., Fors, O., & Seco, A. (2005) · International Journal of Remote Sensing · doi:10.1080/01431160512331314056 · Cited by 189 · see citing works
First‐trimester screening for fetal aneuploidy: biochemistry and nuchal translucency
Orlandi, F., Damiani, G. B., Hallaban, T. W., Krantz, D., & Macri, J. N. (1997) · Ultrasound in Obstetrics and Gynecology · doi:10.1046/j.1469-0705.1997.10060381.x · Cited by 112 · see citing works
Noninvasive prenatal testing for aneuploidy–ready for prime time?
Chitty, L. S., Hill, M. K., White, H., Wright, D. E., & Stephen Morris, A. (2012) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2012.02.021 · Cited by 77 · see citing works
Semi‐automated system for measurement of nuchal translucency thickness
Moratalla, J., Pintoffl, K., Minekawa, R., Lachmann, R., Wright, D., & Nicolaides, K. H. (2010) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.7737 · Cited by 64 · see citing works
Automatic fetal head measurements from sonographic images
Chalana, V., Winter, T. C., Cyr, D. R., Haynor, D. R., & Kim, Y. (1996) · Academic Radiology · doi:10.1016/s1076-6332(96)80187-5 · Cited by 56 · see citing works
Ballarò, B., Florena, A. M., Franco, V., Tegolo, D., Tripodo, C., & Valenti, C. F. (2008) · Medical Image Analysis · doi:10.1016/j.media.2008.04.001 · Cited by 38 · see citing works
Self-citationLocal operators to detect regions of interest
Gesù, V. D., Valenti, C. F., & Strinati, L. (1997) · Pattern Recognition Letters · doi:10.1016/s0167-8655(97)00084-6 · Cited by 37 · see citing works
Self-citationLee, Y.-B., Kim, M., & Kim, M. (2007) · Medical & Biological Engineering & Computing · doi:10.1007/s11517-007-0225-7 · Cited by 37 · see citing works
Lai, K. W., Min, T. Y., Arooj, A., & Supriyanto, E. (2010) · doi:10.5555/1865351.1865353 · Cited by 35 · see citing works
A hierarchical model for automatic nuchal translucency detection from ultrasound images
Deng, Y., Wang, Y., Chen, P., & Yu, J. (2012) · Computers in Biology and Medicine · doi:10.1016/j.compbiomed.2012.04.002 · Cited by 31 · see citing works
Bernardino, F., Cardoso, R., Montenegro, N. A. M. D. M., Bernardes, J., & de Sá, J. M. (1998) · Ultrasound in Medicine & Biology · doi:10.1016/s0301-5629(97)00235-4 · Cited by 31 · see citing works
Increased nuchal translucency and congenital heart disease
Mogra, R., Alabbad, N., & Hyett, J. A. (2012) · Early Human Development · doi:10.1016/j.earlhumdev.2012.02.009 · Cited by 26 · see citing works
Automated detection of fetal nuchal translucency based on hierarchical structural model
Deng, Y., Wang, Y., & Chen, P. (2010) · Proceedings - IEEE Symposium on Computer-Based Medical Systems · doi:10.1109/cbms.2010.6042618 · Cited by 25 · see citing works
Cho, H. Y., Kwon, J., Kim, Y. H., Lee, K. H., Kim, J., Kim, S. Y., & Park, Y. W. (2011) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.8996 · Cited by 21 · see citing works
A non-parametric segmentation methodology for oral videocapillaroscopic images
Bellavia, F., Cacioppo, A., Lupaşcu, C. A., Messina, P., Scardina, G. A., Tegolo, D., & Valenti, C. F. (2014) · Computer Methods and Programs in Biomedicine · doi:10.1016/j.cmpb.2014.02.009 · Cited by 20 · see citing works
Self-citationA Semi-automated Method for the Measurement of the Fetal Nuchal Translucency in Ultrasound Images
Catanzariti, E., Fusco, G., Isgrò, F., Masecchia, S., Prevete, R., & Santoro, M. (2009) · Lecture notes in computer science · doi:10.1007/978-3-642-04146-4_66 · Cited by 18 · see citing works
Nuchal translucency as a predictor of adverse pregnancy outcome
Piazze, J., Anceschi, M. M., Cerekja, A., Torre, R. L., Pala, A., Papa, A., & Cosmi, E. (2007) · International Journal of Gynecology & Obstetrics · doi:10.1016/j.ijgo.2007.02.010 · Cited by 17 · see citing works
Anzalone, A., Fusco, G., Isgrò, F., Orlandi, E., Prevete, R., Sciortino, G., Tegolo, D., & Valenti, C. F. (2013) · Proceedings - IEEE Symposium on Computer-Based Medical Systems · doi:10.1109/cbms.2013.6627795 · Cited by 17 · see citing works
Self-citationSymmetry as an Intrinsically Dynamic Feature
Gesù, V. D., Tabacchi, M. E., & Zavidovique, B. (2010) · Symmetry · doi:10.3390/sym2020554 · Cited by 7 · see citing works
Greene, N., & Platt, L. D. (2004) · Prenatal Diagnosis · doi:10.1002/pd.812 · Cited by 4 · see citing works
Setting up a Nuchal Translucency Clinic
Onyeacholem, I., Kleiner, B. C., Hull, A., Chibuk, J., Romine, L. E., Anton, T., & Pretorius, D. H. (2015) · Ultrasound Quarterly · doi:10.1097/ruq.0000000000000161 · Cited by 3 · see citing works
Delmonte, R., & Antonio, G. (1984) · Cited by 2 · see citing works
Flagged first, then by citations
2 of the 30 references couldn’t be matched to a known paper.
Research works printed but not linked: 1
- Jain R, Kasturi R, Schunck B (1995). Machine Vision. New York: McGraw-Hill.
Cited by
Sorted by citations
Castagnoli, L., Cancila, V., Cordoba-Romero, S. L., Faraci, S., Talarico, G., Belmonte, B., Iorio, M. V., Milani, M., Volpari, T., Chiodoni, C., et al. (2019) · Oncogene · doi:10.1038/s41388-019-0700-2 · Cited by 184 · see citing works
Artificial intelligence in obstetric ultrasound: A scoping review.
Horgan, R., Nehme, L., & Abuhamad, A. (2023) · Prenatal Diagnosis · doi:10.1002/pd.6411 · Cited by 72 · see citing works
“18 Three studies focused on the detection of the mid ‐ sagittal plane of the fetus, with one study focusing on 2D ultrasound 19 and two studies on 3D ultrasound.”
BackgroundArtificial Intelligence in Prenatal Ultrasound Diagnosis
He, F., Wang, Y., Xiu, Y., Zhang, Y., & Chen, L. (2021) · Frontiers in Medicine · doi:10.3389/fmed.2021.729978 · Cited by 62 · see citing works
Automatic detection and measurement of nuchal translucency
Sciortino, G., Tegolo, D., & Valenti, C. (2017) · Computers in Biology and Medicine · doi:10.1016/j.compbiomed.2017.01.008 · Cited by 55 · see citing works
Self-citationGao, Y., Yu, X., Wu, C., Zhou, W., Lei, X., & Zhuang, Y. (2019) · Journal of Healthcare Engineering · doi:10.1155/2019/2745183 · Cited by 19 · see citing works
Sriraam, N., Chinta, B., Seshadri, S., & Suresh, S. (2025) · Artificial Intelligence Review · doi:10.1007/s10462-025-11160-7 · Cited by 18 · see citing works
Sciortino, G., Tegolo, D., & Valenti, C. F. (2017) · International Conference on Information, Communication and Automation Technologies (ICAT) · doi:10.1109/icat.2017.8171631 · Cited by 6 · see citing works
Self-citationChen, C., Wang, C.-A., Cyue, J.-H., Chen, C.-P., Sun, F.-J., Chen, Y., Wang, L., Chang, C.-W., Tsai, B.-Y., & Chen, K. (2025) · Taiwanese Journal of Obstetrics and Gynecology · doi:10.1016/j.tjog.2025.08.001 · Cited by 4 · see citing works
Sciortino, G., Tegolo, D., & Valenti, C. F. (2017) · Lecture notes in computer science · doi:10.1007/978-3-319-59226-8_25 · Cited by 3 · see citing works
Self-citationIntegrative review of intelligent nuchal translucency for genetic disorder
Pawar, S. S., & Nikose, M. (2025) · Computational Biology and Chemistry · doi:10.1016/j.compbiolchem.2025.108597 · Cited by 2 · see citing works
A genetic approach to the maximum common subgraph problem
Valenti, C. F. (2019) · International Conference on Computer Systems and Technologies (CompSysTech) · doi:10.1145/3345252.3345272 · Cited by 1 · see citing works
Self-citationA Wavelet approach to extract main features from indirect immunofluorescence images
Palermo, R. D., Cascio, D., Raso, G., & Tegolo, D. (2019) · International Conference on Computer Systems and Technologies (CompSysTech) · doi:10.1145/3345252.3345264 · Cited by 1 · see citing works
Self-citationKreft, M. (2017) · Image Analysis & Stereology · doi:10.5566/ias.1731 · Cited by 1 · see citing works
Stellenwert der KI im pränatalen sonographischen Screening
Ritgen, J. (2022) · Die Gynäkologie · doi:10.1007/s00129-022-04995-6
Sriraam, N., Chinta, B., Suresh, S., & Sudharshan, S. (2024) · SSRN Electronic Journal · doi:10.2139/ssrn.4812061
FUSEP: A Multi-Center Benchmark for Diverse Tasks in Fetal Ultrasound Screening Early Pregnancy
Pu, B., Yang, J., Wang, L., Tan, Y., He, G., Dong, X., Lin, Q., Guo, J., Yang, L., Liu, Z., et al. (2026) · ACM SIGKDD Conference on Knowledge Discovery and Data Mining (KDD) · doi:10.1145/3770855.3817453
- Authors
- Sciortino, G., Orlandi, E., Valenti, C., & Tegolo, D.
- Affiliations
- University of Palermo (IT)
- Venue
- Image Analysis & Stereology
- Published
- 2016-04-14
- Volume
- 35
- Issue
- 2
- Pages
- 105
- ISSN
- 1580-3139 (ISSN-L)
- 1854-5165
- OpenAlex
- W2335957243
- Cited by
- 16
- References
- 30
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 1 · 2023: 1 · 2022: 1 · 2021: 1 · 2019: 4 · 2017: 4
- FWCI
- 1.81
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- Image Analysis & Stereology (publishedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Nova Science Publishers (Nova Science Publishers, Inc.) (submittedVersion, other-oa)
- Topics
- Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Medical Image Segmentation Techniques
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Prenatal Screening and Diagnostics
- Health Sciences › Dentistry › Oral Surgery › Dental Radiography and Imaging
- Keywords
- nuchal translucency, prenatal ultrasound, first trimester, wavelet analysis, neural network classifier, trisomy screening, chromosomal abnormalities
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