Simultaneous single-and multi-contrast super-resolution for brain MRI images based on a convolutional neural network
Abstract
In magnetic resonance imaging (MRI), the acquired images are usually not of high enough resolution due to constraints such as long sampling times and patient comfort. High-resolution MRI images can be obtained by super-resolution techniques, which can be grouped into two categories: single-contrast super-resolution and multi-contrast super-resolution, where the former has no reference information, and the latter applies a high-resolution image of another modality as a reference. In this paper, we propose a deep convolutional neural network model, which performs single- and multi-contrast super-resolution reconstructions simultaneously. Experimental results on synthetic and real brain MRI images show that our convolutional neural network model outperforms state-of-the-art MRI super-resolution methods in terms of visual quality and objective quality criteria such as peak signal-to-noise ratio and structural similarity.
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Deep learning approaches have been introduced for MRI super-resolution.
“Recently deep learning approaches has been introduced, e.g. generating super-resolution single (no reference information) and multi-contrast (applying a high-resolution image of another modality as reference) brain MR images using CNNs [197]; constructing superresolution brain MRI by a CNN stacked by multi-scale fusion units [198]; and super-resolution musculoskeletal MRI ('DeepResolve') [199].”
From An overview of deep learning in medical imaging focusing on MRI (2019) · cites this paper as [197]
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- Authors
- Zeng, K., Zheng, H., Cai, C., Yang, Y., Zhang, K., & Chen, Z.
- Affiliations
- Xiamen University (CN)
- Corresponding author
- Chen, Zhong
- Venue
- Computers in Biology and Medicine
- Publisher
- Elsevier BV
- Published
- 2018-08
- Volume
- 99
- Pages
- 133-141
- ISSN
- 0010-4825 (ISSN-L)
- OpenAlex
- W2808495892
- Cited by
- 161
- References
- 47
- Citations by year
- 2026: 9 · 2025: 23 · 2024: 22 · 2023: 30 · 2022: 28 · 2021: 24 · 2020: 15 · 2019: 8 · 2018: 2
- FWCI
- 6.13
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Computers in Biology and Medicine (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation of China (61601389, 11761141010, 81671674, U1632274, 61601386)
- Topics
- Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Advanced Image Processing Techniques
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced MRI Techniques and Applications
- Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Image and Signal Denoising Methods
- Keywords
- MRI super-resolution, brain MRI, simultaneous reconstruction, convolutional neural networks, image reconstruction, synthetic MRI
- MeSH terms
- Algorithms, Brain, Humans, Magnetic Resonance Imaging, Neural Networks, Computer, Signal-To-Noise Ratio
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