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Cited by 134Neuroendocrine regulation and behaviorMemory and Neural MechanismsNeuroscience and Neuropharmacology Research

Organization of neural circuits underlying social behavior: A consideration of the medial amygdala

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Raam, Tara, Hong, Weizhe·2021·Current Opinion in Neurobiology
DOI 10.1016/j.conb.2021.02.008PMC PMC8243811
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Abstract

The medial amygdala (MeA) is critical for the expression of a broad range of social behaviors, and is also connected to many other brain regions that mediate those same behaviors. Here, we summarize recent advances toward elucidating mechanisms that enable the MeA to regulate a diversity of social behaviors, and also consider what role the MeA plays within the broader network of regions that orchestrate social sensorimotor transformations. We outline the molecular, anatomical, and electrophysiological features of the MeA that segregate distinct social behaviors, propose experimental strategies to disambiguate sensory representations from behavioral function in the context of a social interaction, and consider to what extent MeA function may overlap with other regions mediating similar behaviors.

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Cited by

Sorted by citations

Authors
Raam, T., & Hong, W.
Affiliations
University of California, Los Angeles (US)
Corresponding author
Hong, Weizhe
ORCID
Venue
Current Opinion in Neurobiology
Publisher
Elsevier BV
Published
2021-06
Volume
68
Pages
124-136
ISSN
0959-4388 (ISSN-L)
DOI
10.1016/j.conb.2021.02.008
PMC
PMC8243811
OpenAlex
W3159665035
Cited by
134
References
17
Citations by year
2026: 20 · 2025: 33 · 2024: 29 · 2023: 27 · 2022: 20 · 2021: 5
FWCI
3.18
Type
journal article
Language
en
Open access
Licence
Locations
  • Current Opinion in Neurobiology (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
  • eScholarship (California Digital Library) (submittedVersion)
Funders
  • National Institutes of Health (T32-NS048004, RF1-DA048811, R01-NS113124, F32-MH123049)
  • Esther A and Joseph Klingenstein Fund Inc
  • Searle Scholars Program
  • Edward Mallinckrodt Jr Foundation
  • W M Keck Foundation
  • Bert L and N Kuggie Vallee Foundation
  • McKnight Foundation
  • McKnight Endowment Fund for Neuroscience
  • David and Lucile Packard Foundation
Topics
  • Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Keywords
medial amygdala, social behavior, neural circuits, sensory representation, social interaction, electrophysiology, molecular mechanisms, structural connectivity
MeSH terms
Amygdala, Social Behavior, Electrophysiological Phenomena

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