The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
Pathways and functions of gut microbiota metabolism impacting host physiology
Open accessAbstract
The bacterial populations in the human intestine impact host physiological functions through their metabolic activity. In addition to performing essential catabolic and biotransformation functions, the gut microbiota produces bioactive small molecules that mediate interactions with the host and contribute to the neurohumoral axes connecting the intestine with other parts of the body. This review discusses recent progress in characterizing the metabolic products of the gut microbiota and their biological functions, focusing on studies that investigate the responsible bacterial pathways and cognate host receptors. Several key areas are highlighted for future development: context-based analysis targeting pathways; integration of analytical approaches; metabolic modeling; and synthetic systems for in vivo manipulation of microbiota functions. Prospectively, these developments could further our mechanistic understanding of host-microbiota interactions.
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Host-gut microbiota metabolic interactions
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Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice
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Phytochemicals as antibiotic alternatives to promote growth and enhance host health
Lillehoj, H., Liu, Y., Calsamiglia, S., Fernandez-Miyakawa, M. E., Chi, F., Cravens, R. L., Oh, S., & Gay, C. G. (2018) · Veterinary Research · doi:10.1186/s13567-018-0562-6 · Cited by 515
Defining the role of Parasutterella, a previously uncharacterized member of the core gut microbiota
Ju, T., Kong, J. Y., Stothard, P., & Willing, B. P. (2019) · The ISME Journal · doi:10.1038/s41396-019-0364-5 · Cited by 494
Gut microbiota and cardiovascular disease: opportunities and challenges
Kazemian, N., Mahmoudi, M., Halperin, F., Wu, J. C., & Pakpour, S. (2020) · Microbiome · doi:10.1186/s40168-020-00821-0 · Cited by 384
Microbiome therapeutics — Advances and challenges
Mimee, M., Citorik, R. J., & Lu, T. K. (2016) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2016.04.032 · Cited by 317
Metadata
- Authors
- Krishnan, S., Alden, N., & Lee, K.
- Venue
- Current Opinion in Biotechnology
- Publisher
- Elsevier BV
- Published
- 2015-12
- Volume
- 36
- Pages
- 137-145
- ISSN
- 0958-1669 (ISSN-L)
- OpenAlex
- W1204711231
- Cited by
- 212
- References
- 14
- FWCI
- 1.06
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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