Nicotine: from molecular mechanisms to behaviour

A psychomotor stimulant theory of addiction.

Wise, R. A., & Bozarth, M. A. (1987) · Psychological Review · doi:10.1037/0033-295x.94.4.469 · Cited by 2,747

The psychology and neurobiology of addiction: an incentive–sensitization view

Robinson, T. E., & Berridge, K. C. (2000) · Addiction · doi:10.1046/j.1360-0443.95.8s2.19.x · Cited by 1,507

Addiction and the brain: The neurobiology of compulsion and its persistence

Hyman, S. E., & Malenka, R. C. (2001) · Nature reviews. Neuroscience · doi:10.1038/35094560 · Cited by 1,337

Putting a spin on the dorsal-ventral divide of the striatum

Voorn, P., Vanderschuren, L. J. M. J., Groenewegen, H. J., Robbins, T. W., & Pennartz, C. M. A. (2004) · Trends in Neurosciences · doi:10.1016/j.tins.2004.06.006 · Cited by 1,188

Nucleus accumbens shell and core dopamine: differential role in behavior and addiction

Di Chiara, G. (2002) · Behavioural Brain Research · doi:10.1016/s0166-4328(02)00286-3 · Cited by 996

The mesolimbic dopaminergic system is implicated in the reinforcing effects of nicotine

Corrigall, W. A., Franklin, K. B. J., Coen, K. M., & Clarke, P. B. S. (1992) · Psychopharmacology · doi:10.1007/bf02245149 · Cited by 829

Self-administered nicotine activates the mesolimbic dopamine system through the ventral tegmental area

Corrigall, W. A., Coen, K. M., & Adamson, K. L. (1994) · Brain Research · doi:10.1016/0006-8993(94)90401-4 · Cited by 740

Long-term potentiation of excitatory inputs to brain reward areas by nicotine

Mansvelder, H. D., & McGehee, D. S. (2000) · Neuron · doi:10.1016/s0896-6273(00)00042-8 · Cited by 720

Neurotransmitter regulation of dopamine neurons in the ventral tegmental area

Kalivas, P. W. (1993) · Brain Research Reviews · doi:10.1016/0165-0173(93)90008-n · Cited by 710

Synaptic mechanisms underlie nicotine-induced excitability of brain reward areas

Mansvelder, H. D., Keath, J. R., & McGehee, D. S. (2002) · Neuron · doi:10.1016/s0896-6273(02)00625-6 · Cited by 701

Nicotine and methamphetamine share discriminative stimulus effects

Gatch, M. B., Flores, E., & Forster, M. J. (2007) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2007.08.020 · Cited by 35

Positive allosteric modulation of α4β2 nicotinic acetylcholine receptors as a new approach to smoking reduction: evidence from a rat model of nicotine self-administration

Liu, X. (2013) · Psychopharmacology · doi:10.1007/s00213-013-3145-2 · Cited by 35

A biopsychosocial approach to examining tobacco‐related health disparities among racially classified social groups

Fernander, A., Shavers, V. L., & Hammons, G. (2007) · Addiction · doi:10.1111/j.1360-0443.2007.01954.x · Cited by 33

Cellular events in nicotine addiction

Penton, R. E., & Lester, R. A. J. (2009) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2009.01.001 · Cited by 33

Differential involvement of the endocannabinoid system in short- and long-term expression of incentive learning supported by nicotine in rats

Forget, B., Barthélémy, S., Saurini, F., Hamon, M., & Thiébot, M.-H. (2006) · Psychopharmacology · doi:10.1007/s00213-006-0525-x · Cited by 32

Inhibitory avoidance memory deficit induced by scopolamine: Interaction of cholinergic and glutamatergic systems in the ventral tegmental area

Mahmoodi, G., Ahmadi, S., Pourmotabbed, A., Oryan, S., & Zarrindast, M. (2010) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2010.04.004 · Cited by 32

Effects of Mecamylamine on Alcohol Consumption and Preference in Male C57BL/6J Mice

Farook, J. M., Lewis, B., Gaddis, J. G., Littleton, J. M., & Barron, S. (2009) · Pharmacology · doi:10.1159/000219488 · Cited by 32

The possible contribution of neuronal nicotinic acetylcholine receptors in depression

Bertrand, D. (2005) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2005.7.3/dbertrand · Cited by 30

Emerging concepts: novel integration of in vivo approaches to localize the function of nicotinic receptors

Maskos, U. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.04224.x · Cited by 31

Hypocretin mechanisms in nicotine addiction: evidence and speculation

Corrigall, W. A. (2009) · Psychopharmacology · doi:10.1007/s00213-009-1588-2 · Cited by 29

N-Methyl-d-aspartate receptors in the ventral tegmental area are involved in retrieval of inhibitory avoidance memory by nicotine

Ahmadi, S., Zarrindast, M., Nouri, M., Haeri-Rohani, A., & Rezayof, A. (2007) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2007.07.001 · Cited by 29

The epigenetic effect of nicotine on dopamine D1 receptor expression in rat prefrontal cortex

Gözen, O., Balkan, B., Yildirim, E., Koylu, E. O., & Pöğün, Ş. (2013) · Synapse · doi:10.1002/syn.21659 · Cited by 32

Effects of blockade of α4β2 and α7 nicotinic acetylcholine receptors on cue-induced reinstatement of nicotine-seeking behaviour in rats

Liu, X. (2013) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145713000874 · Cited by 31

Mecamylamine, dihydro-β-erythroidine, and dextromethorphan block conditioned responding evoked by the conditional stimulus effects of nicotine

Struthers, A. M., Wilkinson, J. L., Dwoskin, L. P., Crooks, P. A., & Bevins, R. A. (2009) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2009.09.012 · Cited by 28

Selective CRF2 receptor agonists ameliorate the anxiety- and depression-like state developed during chronic nicotine treatment and consequent acute withdrawal in mice

Bagosi, Z., Palotai, M., Simon, B., Bokor, P., Búzás, A., Balangó, B., Pintér, D., Jászberényi, M., Csabafi, K., & Szabó, G. (2016) · Brain Research · doi:10.1016/j.brainres.2016.09.044 · Cited by 28

Inhibition of alpha7 nicotinic receptors in the ventral hippocampus selectively attenuates reinstatement of morphine‐conditioned place preference and associated changes in AMPA receptor binding

Wright, V. L., Georgiou, P., Bailey, A., Heal, D. J., Bailey, C. P., & Wonnacott, S. (2018) · Addiction Biology · doi:10.1111/adb.12624 · Cited by 26

Lobeline, a nicotinic partial agonist attenuates alcohol consumption and preference in male C57BL/6J mice

Farook, J. M., Lewis, B., Gaddis, J. G., Littleton, J. M., & Barron, S. (2009) · Physiology & Behavior · doi:10.1016/j.physbeh.2009.02.031 · Cited by 27

Smoke Extracts and Nicotine, but not Tobacco Extracts, Potentiate Firing and Burst Activity of Ventral Tegmental Area Dopaminergic Neurons in Mice

Marti, F., Arib, O., Morel, C., Dufresne, V., Maskos, U., Corringer, P., de Beaurepaire, R., & Fauré, P. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2011.112 · Cited by 36

Orthosteric and Allosteric Ligands of Nicotinic Acetylcholine Receptors for Smoking Cessation

Mohamed, T. S., Jayakar, S. S., & Hamouda, A. K. (2015) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2015.00071 · Cited by 27

Review Paper: Role of Nitric Oxide on Dopamine Release and Morphine-Dependency

Motahari, A. A., Sahraei, H., & Meftahi, G. H. (2016) · Basic and Clinical Neuroscience Journal · doi:10.15412/j.bcn.03070401 · Cited by 27

Partial Recovery of Striatal Nicotinic Receptors in 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-Lesioned Monkeys with Chronic Oral Nicotine

Bordia, T., Parameswaran, N., Fan, H., Langston, J., McIntosh, J. M., & Quik, M. (2006) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.106.106997 · Cited by 31

The Impact of Electronic Nicotine Delivery System (ENDS) Flavors on Nicotinic Acetylcholine Receptors and Nicotine Addiction-Related Behaviors

Cooper, S. Y., & Henderson, B. J. (2020) · Molecules · doi:10.3390/molecules25184223 · Cited by 29

Genetic Influences on Smoking

Koudsi, N. A., & Tyndale, R. F. (2005) · Therapeutic Drug Monitoring · doi:10.1097/01.ftd.0000179842.63515.c6 · Cited by 25

Ghrelin and Nicotine Stimulate Equally the Dopamine Release in the Rat Amygdala

Palotai, M., Bagosi, Z., Jászberényi, M., Csabafi, K., Dochnal, R., Manczinger, M., Telegdy, G., & Szabó, G. (2013) · Neurochemical Research · doi:10.1007/s11064-013-1105-1 · Cited by 26

Nicotine Exposure during the Third Trimester Equivalent of Human Gestation: Time Course of Effects on the Central Cholinergic System of Rats

Nunes‐Freitas, A. L., Ribeiro‐Carvalho, A., Lima, C. S., Dutra-Tavares, A. C., Manhães, A. C., Lisboa, P. C., OLIVEIRA, E. B. D., de Moura, E. G., Filgueiras, C. C., & Abreu‐Villaça, Y. (2011) · Toxicological Sciences · doi:10.1093/toxsci/kfr147 · Cited by 26

Nicotine Modulates Mitochondrial Dynamics in Hippocampal Neurons

Godoy, J. A., Valdivieso, Á. G., & Inestrosa, N. C. (2018) · Molecular Neurobiology · doi:10.1007/s12035-018-1034-8 · Cited by 25

Significant modulation of mitochondrial electron transport system by nicotine in various rat brain regions

Wang, J., Kim, J.-M., Donovan, D. M., Becker, K. G., & Li, M. D. (2009) · Mitochondrion · doi:10.1016/j.mito.2009.01.008 · Cited by 25

Smoking reduces language lateralization: A dichotic listening study with control participants and schizophrenia patients

Hahn, C., Neuhaus, A. H., Pöğün, Ş., Dettling, M., Kotz, S. A., Hahn, E. W., Brüne, M., & Güntürkün, O. (2011) · Brain and Cognition · doi:10.1016/j.bandc.2011.03.015 · Cited by 25

Effects of nicotine self-administration on incentive salience in male Sprague Dawley rats

Overby, P. F., Daniels, C. W., Franco, A. P. D., Goenaga, J. G., Powell, G. L., Gipson, C. D., & Sanabria, F. (2018) · Psychopharmacology · doi:10.1007/s00213-018-4829-4 · Cited by 25

Sex differences in nicotine levels following repeated intravenous injection in rats are attenuated by gonadectomy

Harrod, S. B., Booze, R. M., & Mactutus, C. F. (2006) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2006.12.004 · Cited by 25

Altered thalamo-cortical resting state functional connectivity in smokers

Wang, C., Bai, J., Wang, C., von Deneen, K. M., Yuan, K., & Cheng, J. (2017) · Neuroscience Letters · doi:10.1016/j.neulet.2017.05.038 · Cited by 24

Differential effects of alkaloids on memory in rodents

Callahan, P., Terry, A., Peitsch, M., Hoeng, J., & Koshibu, K. (2021) · Scientific Reports · doi:10.1038/s41598-021-89245-w · Cited by 21

NMDA‐mediated modulation of dopamine release is modified in rat prefrontal cortex and nucleus accumbens after chronic nicotine treatment

Grilli, M., Pittaluga, A., Merlo‐Pich, E., & Marchi, M. (2008) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2008.05792.x · Cited by 24

Tobacco addiction: A biochemical model of nicotine dependence

Ortells, M. O., & Barrantes, G. E. (2009) · Medical Hypotheses · doi:10.1016/j.mehy.2009.11.004 · Cited by 26

FTIR microspectroscopic analysis of the effects of certain drugs on oxidative stress and brain protein structure

Carmona, P., Rodríguez‐Casado, A., Alvarez, I., de Miguel, E., & Tolédano, A. (2008) · Biopolymers · doi:10.1002/bip.20944 · Cited by 23

Fatty acid amide hydrolase (FAAH) inactivation confers enhanced sensitivity to nicotine‐induced dopamine release in the mouse nucleus accumbens

Pavón, F. J., Serrano, A., Sidhpura, N., Polis, I. Y., Stouffer, D. G., de Fonseca, F. R., Cravatt, B. F., Martin‐Fardon, R., & Parsons, L. H. (2017) · Addiction Biology · doi:10.1111/adb.12531 · Cited by 25

Strain‐ and region‐specific gene expression profiles in mouse brain in response to chronic nicotine treatment

Wang, J., Gutala, R. V., Hwang, Y. Y., Kim, J. ‐., Konu, Ö., Ma, J. Z., & Li, M. D. (2007) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2007.00328.x · Cited by 25

Nicotine and Ethanol Activate Protein Kinase A Synergistically via Gi βγ Subunits in Nucleus Accumbens/Ventral Tegmental Cocultures: The Role of Dopamine D1/D2 and Adenosine A2A Receptors

Inoue, Y., Yao, L., Hopf, F. W., Fan, P., Jiang, Z., Bonci, A., & Diamond, I. (2007) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.107.120675 · Cited by 23

Nicotinic Ligands Modulate Ethanol-Induced Dopamine Function in Mice

Sajja, R. K., Dwivedi, C., & Rahman, S. (2010) · Pharmacology · doi:10.1159/000317063 · Cited by 22

Region‐specific effects of N , N ′‐dodecane‐1,12‐diyl‐bis‐3‐picolinium dibromide on nicotine‐induced increase in extracellular dopamine in vivo

Rahman, S., Zhang, Z., Papke, R. L., Crooks, P. A., Dwoskin, L. P., & Bardo, M. T. (2007) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0707612 · Cited by 22

L-type calcium channel ligands block nicotine-induced signaling to CREB by inhibiting nicotinic receptors.

Wheeler, D. G., Barrett, C. F., & Tsien, R. (2006) · Neuropharmacology · doi:10.1016/j.neuropharm.2006.02.010 · Cited by 25

Alpha7 Nicotinic Acetylcholine Receptor Expression and Activity During Neuronal Differentiation of PC12 Pheochromocytoma Cells

Nery, A. A., Resende, R. R., Martins, A. H. B., Trujillo, C. A., Eterović, V. A., & Ulrich, H. (2010) · Journal of Molecular Neuroscience · doi:10.1007/s12031-010-9369-2 · Cited by 22

Nicotine exposure beginning in adolescence enhances the acquisition of methamphetamine self-administration, but not methamphetamine-primed reinstatement in male rats

Pipkin, J. A., Kaplan, G. J., Plant, C. P., Eaton, S. E., Gil, S. M., Zavala, A. R., & Crawford, C. A. (2014) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2014.06.029 · Cited by 21

α7 nicotinic acetylcholine receptor in memory processing

Pastor, V. E., & Medina, J. H. (2023) · European Journal of Neuroscience · doi:10.1111/ejn.15913 · Cited by 24

Ethanol blocks nicotine-induced seizures in mice: comparison with midazolam and baclofen.

Korkosz, A., Zatorski, P., Taracha, E., Płażnik, A., Kostowski, W., & Bieńkowski, P. (2006) · Alcohol · doi:10.1016/j.alcohol.2006.12.001 · Cited by 22

Bidirectional role of dopamine in learning and memory-active forgetting

Díaz, F. C., Caffino, L., & Fumagalli, F. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.10.011 · Cited by 24

Development of an anti-cotinine vaccine to potentiate nicotine-based smoking cessation strategies

Oliver, J. L., Pashmi, G., Barnett, P., Mettens, P., Biemans, R., Monteyne, P., Palmantier, R., Gallagher, T. C., Ramaya, S., & Wonnacott, S. (2007) · Vaccine · doi:10.1016/j.vaccine.2007.08.019 · Cited by 19

Specific inhibitory effect of amyloid-β on presynaptic muscarinic receptor subtypes modulating neurotransmitter release in the rat nucleus accumbens

Grilli, M., Lagomarsino, F., Zappettini, S., Preda, S., Mura, E., Govoni, S. M., & Marchi, M. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2010.01.058 · Cited by 20

Actions of Anesthetics on Excitatory Transmitter-Gated Channels

Akk, G., Mennerick, S. J., & Steinbach, J. H. (2008) · Springer eBooks · doi:10.1007/978-3-540-74806-9_3 · Cited by 19

Ascorbic acid antagonizes nicotine-induced place preference and behavioral sensitization in mice

Sahraei, H., Aliabadi, A. A., Zarrindast, M., Ghoshooni, H., Nasiri, A. R., Barzegari, A. A., Yari, M., Zardooz, H., Hosseinmardi, L., Faraji, N., et al. (2007) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2006.12.019 · Cited by 19

Prefrontal Gamma-Aminobutyric Acid Type A Receptor Insertion Controls Cue-Induced Relapse to Nicotine Seeking

Lubbers, B. R., van Mourik, Y., Schetters, D., Smit, A. B., Vries, T. J. D., & Spijker, S. (2014) · Biological Psychiatry · doi:10.1016/j.biopsych.2014.02.001 · Cited by 18

Inhibitory influence of mecamylamine on ethanol withdrawal-induced symptoms in C57BL/6J mice

Bhutada, P., Mundhada, Y. R., Bansod, K. U., Umathe, S. N., Kahale, V. P., Dixit, P. V., & Mundhada, D. R. (2010) · Behavioural Pharmacology · doi:10.1097/fbp.0b013e328337be54 · Cited by 16

Inhibitory influence of mecamylamine on the development and the expression of ethanol-induced locomotor sensitization in mice

Bhutada, P., Mundhada, Y. R., Bansod, K. U., Dixit, P. V., Umathe, S. N., & Mundhada, D. R. (2010) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2010.05.015 · Cited by 16

The sensitizing effect of acute nicotine on amphetamine-stimulated behavior and dopamine efflux requires activation of β2 subunit-containing nicotinic acetylcholine receptors and glutamate N-methyl-d-aspartate receptors

Kim, M. N., Jutkiewicz, E. M., Zhang, M., & Gnegy, M. E. (2010) · Neuropharmacology · doi:10.1016/j.neuropharm.2010.10.003 · Cited by 15

Functional 7-containing nicotinic acetylcholine receptors localize to cell bodies and proximal dendrites in the rat substantia nigra pars reticulata

Poisik, O. V., Shen, J., Jones, S., & Yakel, J. L. (2008) · The Journal of Physiology · doi:10.1113/jphysiol.2007.149963 · Cited by 17

Effects of nicotine on bone during orthodontic tooth movement in male rats

Bakathir, M. A., Linjawi, A. I., Omar, S. S., Aboqura, A. B., & Hassan, A. H. (2016) · Saudi Medical Journal · doi:10.15537/smj.2016.10.15159 · Cited by 16

Effects of ethanol on nicotine-induced conditioned place preference in C57BL/6J mice.

Korkosz, A., Zatorski, P., Taracha, E., Płażnik, A., Kostowski, W., & Bieńkowski, P. (2006) · Progress in Neuro-psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2006.04.024 · Cited by 17

Repeated treatment with nicotine induces phosphorylation of NMDA receptor NR2B subunit in the brain regions involved in behavioral sensitization

Nakajima, A., Kinugasa, Y., Torii, J., Hishinuma, T., Tomioka, Y., Yamada, K., & Yamakuni, T. (2012) · Neuroscience Letters · doi:10.1016/j.neulet.2012.07.022 · Cited by 14

Functional benefit of smoking cessation in severe COPD patients undergoing bronchial valve implantation

Pezzuto, A., D’Ascanio, M., Grieco, A., & Rícci, A. (2019) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2019.07.032 · Cited by 14

Nicotine Addiction: Past and Present

Office on Smoking (2010) · Cited by 14

Cholinergic Component of Autism Spectrum Disorder

Mukaetova‐Ladinska, E. B., Westwood, J., & Perry, E. K. (2010) · Springer eBooks · doi:10.1007/978-1-4419-1272-5_9 · Cited by 13

Reevaluating the nicotine delivery kinetics hypothesis

Dar, R., & Frenk, H. (2007) · Psychopharmacology · doi:10.1007/s00213-007-0768-1 · Cited by 13

Smoking modulates language lateralization in a sex-specific way

Hahn, C., Pöğün, Ş., & Güntürkün, O. (2010) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2010.10.014 · Cited by 12

Bis-azaaromatic quaternary ammonium salts as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release: An investigation of binding conformation.

Zheng, G.-R., Zhang, Z.-F., Pivavarchyk, M., Deaciuc, A., Dwoskin, L., & Crooks, P. (2007) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2007.10.052 · Cited by 13

Contrasting effects of the α7 nicotinic receptor antagonist methyllycaconitine in different rat models of heroin reinstatement

Palandri, J., Smith, S. L., Heal, D. J., Wonnacott, S., & Bailey, C. P. (2021) · Journal of Psychopharmacology · doi:10.1177/0269881121991570 · Cited by 11

Targeting Reward-Relevant Nicotinic Receptors in the Discovery of Novel Pharmacotherapeutic Agents to Treat Tobacco Dependence

Dwoskin, L. P., Pivavarchyk, M., Joyce, B. M., Neugebauer, N. M., Zheng, G., Zhang, Z., Bardo, M. T., & Crooks, P. A. (2008) · Nebraska Symposium on Motivation/The Nebraska symposium on motivation · doi:10.1007/978-0-387-78748-0_4 · Cited by 12

Nicotine's enhancing effects on responding maintained by conditioned reinforcers are reduced by pretreatment with mecamylamine, but not hexamethonium, in rats.

Jones, J. S., Raiff, B. R., & Dallery, J. (2010) · Experimental and Clinical Psychopharmacology · doi:10.1037/a0020601 · Cited by 10

Nicotine improves probabilistic reward learning in wildtype but not alpha7 nAChR null mutants, yet alpha7 nAChR agonists do not improve probabilistic learning

Milienne-Petiot, M., Higa, K. K., Grim, A., Deben, D. S., Groenink, L., Twamley, E. W., Geyer, M. A., & Young, J. W. (2018) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2018.08.005 · Cited by 9

Targeting the α4β2- and α7-Subtypes of Nicotinic Acetylcholine Receptors for Smoking Cessation Medication Development.

Nair, L. R., & Liu, X. (2019) · PubMed · Cited by 10

Untangling interactions of a zinc(ii) complex containing a coumarin—porphyrin unit with alkaloids in water solutions: a photophysical study

Santos, C. I. M., Oliveira, E., Santos, H. M., Menezes, J. C. J. M. D. S., Faustino, M. A. F., Cavaleiro, J. A. S., Capelo, J. L., Neves, M. G. P. M. S., & Lodeiro, C. (2015) · Photochemical & Photobiological Sciences · doi:10.1039/c4pp00359d · Cited by 9

Acute MDMA and Nicotine Co-administration: Behavioral Effects and Oxidative Stress Processes in Mice

Budzyńska, B., Wnorowski, A., Kaszubska, K., Biała, G., Kruk-Słomka, M., Kurzepa, J., & Boguszewska‐Czubara, A. (2018) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2018.00149 · Cited by 8

Prenatal Stress as a Factor of the Development of Addictive States

Stratilov, V. A., Tyulkova, E. I., & Vetrovoy, O. V. (2020) · Journal of Evolutionary Biochemistry and Physiology · doi:10.1134/s0022093020060010 · Cited by 9

Acetylsalicylic acid reduces cigarette smoke withdrawal-induced anxiety in rats via modulating the expression of NFĸB, GLT-1, and xCT

Hammad, A. M., Alzaghari, L. F., Alfaraj, M., Al-Qerem, W. A., Talib, W. H., Alasmari, F. F., Amawi, H. A., & Hall, F. S. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.1047236 · Cited by 9

Gates and filters: unveiling the physiological roles of nicotinic acetylcholine receptors in dopaminergic transmission

Wonnacott, S. (2008) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0707583 · Cited by 10

Performance of motor associated behavioural tests following chronic nicotine administration

Ijomone, O. M., Olaibi, O. K., Biose, I. J., Mba, C., Umoren, K. E., & Nwoha, P. U. (2014) · Annals of Neurosciences · doi:10.5214/ans.0972.7531.210203 · Cited by 9

Developmental Nicotine Exposure Alters Synaptic Input to Hypoglossal Motoneurons and Is Associated with Altered Function of Upper Airway Muscles

Wollman, L., Clarke, J., DeLucia, C. M., Levine, R. B., & Fregosi, R. F. (2019) · eNeuro · doi:10.1523/eneuro.0299-19.2019 · Cited by 9

Pharmacological effects of nicotine salts on dopamine release in the nucleus accumbens

Li, X., Lu, L., He, Y., Zhang, H., Zhang, Y., Sheng, H., Chen, M., Ru, J., & Gao, Y. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1279512 · Cited by 13

Characterization of AN317, a novel selective agonist of α6β2-containing nicotinic acetylcholine receptors

Sandager‐Nielsen, K., Ahring, P. K., Klein, J. L., van Hout, M., Thaneshwaran, S., dos Santos, A. B., Jacobsen, T. A., Amrutkar, D. V., Peters, D., Jensen, A. A., et al. (2019) · Biochemical Pharmacology · doi:10.1016/j.bcp.2019.113786 · Cited by 8

The novel nicotinic receptor antagonist N,N′-dodecane-1,12-diyl-bis-3-picolinium dibromide decreases nicotine-induced dopamine metabolism in rat nucleus accumbens

Rahman, S., Neugebauer‎, N. M., Zhang, Z., Crooks, P. A., Dwoskin, L. P., & Bardo, M. T. (2008) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2008.10.037 · Cited by 8

Immunohistochemical increase in cyclooxygenase-2 without apoptosis in different brain areas of subchronic nicotine- and d-amphetamine-treated rats

Tolédano, A., Álvarez, M., Caballero, I., Carmona, P., & de Miguel, E. (2008) · Journal of Neural Transmission · doi:10.1007/s00702-008-0040-9 · Cited by 8

Cocaine and Nicotine Research Illustrates a Range of Hypocretin Mechanisms in Addiction

Baimel, C., Borgland, S. L., & Corrigall, W. A. (2012) · Vitamins and hormones · doi:10.1016/b978-0-12-394623-2.00016-0 · Cited by 8

Neuronal Receptors for Nicotine: Functional Diversity and Developmental Changes

Mansvelder, H. D., & Role, L. W. (2006) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780195183139.003.0021 · Cited by 8

Characterization of AN6001, a positive allosteric modulator of α6β2-containing nicotinic acetylcholine receptors

van Hout, M., Klein, J. L., Ahring, P. K., Brown, D. T., Thaneshwaran, S., dos Santos, A. B., Jensen, A. A., Kohlmeier, K. A., Christophersen, P., & Dyhring, T. (2019) · Biochemical Pharmacology · doi:10.1016/j.bcp.2019.113788 · Cited by 7

The Prenatal Hypoxic Pathology Associated with Maternal Stress Predisposes to Dysregulated Expression of the chrna7 Gene and the Subsequent Development of Nicotine Addiction in Adult Offspring

Stratilov, V. A., Vetrovoy, O. V., Potapova, S., & Tyulkova, E. I. (2024) · Neuroendocrinology · doi:10.1159/000536214 · Cited by 6

Inhibition of acetylcholinesterase activity in brain and behavioral analysis in adult rats after chronic administration of fenproporex

Rezin, G., Scaini, G., Ferreira, G., Cardoso, M. R., Gonçalves, C. L., Constantino, L., Deroza, P. F. P., Ghedim, F. V., Valvassori, S., Resende, W. R., et al. (2012) · Metabolic brain disease · doi:10.1007/s11011-012-9331-9 · Cited by 7

Nicotine-induced behavioral sensitization in an adult rat model of attention deficit/hyperactivity disorder (ADHD)

Watterson, E., Spitzer, A., Watterson, L. R., Brackney, R. J., Zavala, A. R., Olive, M., & Sanabria, F. (2016) · Behavioural Brain Research · doi:10.1016/j.bbr.2016.06.050 · Cited by 4

The role of the SLC6A3 3’ UTR VNTR in nicotine effects on cognitive, affective, and motor function

Schröder, R., Reuter, M., Faßbender, K., Plieger, T., Poulsen, J., Lui, S. S. Y., Chan, R. C. K., & Ettinger, U. (2021) · Psychopharmacology · doi:10.1007/s00213-021-06028-x · Cited by 6

Emerging therapeutic targets for the treatment of nicotine addiction

Kenny, P. J. (2009) · Expert Review of Clinical Pharmacology · doi:10.1586/ecp.09.6 · Cited by 6

Acute Administration of Desformylflustrabromine Relieves Chemically Induced Pain in CD-1 Mice

Weggel, L. A., & Pandya, A. A. (2019) · Molecules · doi:10.3390/molecules24050944 · Cited by 5

Assessment of brain connectome alterations in male chronic smokers using structural and generalized q-sampling MRI

Weng, J., Chuang, Y.-C., Zheng, L.-B., Lee, M., & Ho, M. (2022) · Brain Imaging and Behavior · doi:10.1007/s11682-022-00647-4 · Cited by 5

Chronic Nicotine Alters Nicotinic Receptor-induced Presynaptic Ca2+ Responses in Isolated Nerve Terminals

Dougherty, J. J., Wu, J., Mehta, T. K., Brown, B. R., & Nichols, R. A. (2007) · Neurochemical Research · doi:10.1007/s11064-007-9557-9 · Cited by 5

Sensitization and tolerance with episodic (weekly) nicotine on motor activity in rats

MacPhail, R. C., Farmer, J. D., & Jarema, K. A. (2006) · Neurotoxicology and Teratology · doi:10.1016/j.ntt.2006.11.012 · Cited by 5

Nicotine affects protein complex rearrangement in Caenorhabditis elegans cells

Sobkowiak, R., Zieleziński, A., Karlowski, W. M., & Lesicki, A. (2017) · Drug and Chemical Toxicology · doi:10.1080/01480545.2016.1264411 · Cited by 5

Ghrelin Amplifies the Nicotine-Induced Release of Dopamine in the Bed Nucleus of Stria Terminalis (BNST)

Ayman, J., Palotai, M., Dochnal, R., & Bagosi, Z. (2023) · Biomedicines · doi:10.3390/biomedicines11092456 · Cited by 4

Possible involvement of neuronal nicotinic acetylcholine receptors in compensatory brain mechanisms at early stages of Parkinson's disease

Kryukova, E. V., Shelukhina, I. V., Kolacheva, A. A., Alieva, A. K., Shadrina, M. I., Slominsky, P. A., Kasheverov, I. E., Utkin, Y. N., Ugrumov, M. V., & Tsetlin, V. I. (2017) · Biomeditsinskaya Khimiya · doi:10.18097/pbmc20176303241 · Cited by 4

Relationships between nicotine craving, orexin-leptin levels and temperament character traits among non-treatment seeking health professionals

Aşçıbaşı, K., Deveci, A., Özyurt, B. C., Oran, A., & Taneli, F. (2018) · Psychiatry and Clinical Psychopharmacology · doi:10.1080/24750573.2018.1458433 · Cited by 4

Striatal NOS1 has dimorphic expression and activity under stress and nicotine sensitization

Díaz, D., Murias, A. R., Ávila-Zarza, C. A., Muñoz-Castañeda, R., Aijón, J., Alonso, J. R., & Weruaga, E. (2015) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2015.07.014 · Cited by 4

Pudendal motoneurons of the rat located in separated spinal nuclei possess nicotinic acetylcholine receptors having distinct pharmacological profiles

Ogier, R., Tribollet, E., Bertrand, D., & Raggenbass, M. (2008) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2008.06403.x · Cited by 4

Current Status of Immunologic Approaches to Treating Tobacco Dependence: Vaccines and Nicotine-Specific Antibodies

LeSage, M. G., Keyler, D. E., & Pentel, P. R. (2008) · Springer eBooks · doi:10.1007/978-0-387-76678-2_27 · Cited by 4

The role of nitric oxide in nicotine reward: A place preference study in rats

Barzegari-Sorkheh, A. A., Oryan, S., & Sahraei, H. (2012) · African Journal of Pharmacy and Pharmacology · doi:10.5897/ajpp12.572 · Cited by 3

Neuronal Systems Underlying Behaviors Related to Nicotine Addiction: Neural Circuits and Molecular Genetics

Picciotto, M. R., & Corrigall, W. A. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-09-03338.2002 · Cited by 265

The Neuronal Pathways Mediating the Behavioral and Addictive Properties of Nicotine

Balfour, D. J. K. (2009) · Handbook of Experimental Pharmacology · doi:10.1007/978-3-540-69248-5_8 · Cited by 99

The Neurobiological Bases for the Pharmacotherapy of Nicotine Addiction

Matteo, V. D., Pierucci, M., Giovanni, G. D., Benigno, A., & Esposito, E. (2007) · Current Pharmaceutical Design · doi:10.2174/138161207780618920 · Cited by 60

Behavioural pharmacology of nicotine: multiple mechanisms

Stolerman, I. P. (1991) · British Journal of Addiction · doi:10.1111/j.1360-0443.1991.tb01803.x · Cited by 36

Nicotine Addiction: From Molecules to Behavior

Picciotto, M. R. (1998) · The Neuroscientist · doi:10.1177/107385849800400610 · Cited by 1