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Self-help interventions for symptoms of depression, anxiety and psychological distress in patients with physical illnesses: A systematic review and meta-analysis

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Matcham, F., Rayner, L., Hutton, J., Monk, A., Steel, C., Hotopf, M.·2014·Clinical Psychology Review

Abstract

Psychological distress, depression and anxiety are common in most physical diseases, and self-help interventions, if effective, might be an important approach to improve outcomes as they are inexpensive to provide to large numbers of patients. The primary aim of this review was to assess randomised controlled trials examining the impact of self-help interventions on symptoms of depression, anxiety and psychological distress in patients with physical illness. Systematic searches of electronic databases resulted in twenty-five eligible studies for meta-analysis (n=4211). The results of the primary meta-analyses revealed a significant improvement in depression symptoms, in favour of the intervention group (SMD=-0.13, 95% CI: -0.25, -0.02, p=0.02, I(2)=50%). There were no significant differences in symptoms of anxiety (SMD=-0.10, 95% CI: -0.24, 0.05, p=0.20, I(2)=63%) or psychological distress (SMD=-0.14, 95% CI: -0.40, 0.12, p=0.30, I(2)=72%) between intervention and control conditions. Several subgroup and sensitivity analyses improved effect sizes, suggesting that optimal mental health outcomes may be obtained in patients without neurological conditions, and with interventions based on a therapeutic model (such as cognitive behavioural therapy), and with stress management components. This review demonstrates that with appropriate design and implementation, self-help interventions may potentially improve symptoms of depression in patients with physical conditions.

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  • A number of reviews demonstrate that self-help interventions are effective for depression and anxiety in adults.

    “A number of reviews demonstrate that self-help interventions are effective for depression and anxiety in adults.21,22”

    From Comparative efficacy and acceptability of bibliotherapy for depression and anxiety disorders in children and adolescents: a meta-analysis of randomized clinical trials (2018) · cites this paper as [21]

    The Discussion reports a small significant benefit for depression, but no significant overall benefit for anxiety. The Conclusions say theoretically based self-help materials may modestly improve both outcomes in patients with physical illness. That cautious, population-specific finding does not establish effectiveness for depression and anxiety in adults generally. (LLM, conf=0.88)

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Authors
Matcham, F., Rayner, L., Hutton, J., Monk, A., Steel, C., & Hotopf, M.
Affiliations
  • King's College London (GB)
  • South London and Maudsley NHS Foundation Trust (GB)
Corresponding author
Matcham, F.
Venue
Clinical Psychology Review
Publisher
Elsevier BV
Published
2014-03
Volume
34
Issue
2
Pages
141-157
ISSN
0272-7358 (ISSN-L)
OpenAlex
W1988661281
Cited by
85
References
19
Citations by year
2026: 2 · 2025: 6 · 2024: 7 · 2023: 8 · 2022: 10 · 2021: 5 · 2020: 5 · 2019: 6 · 2018: 9 · 2017: 6 · 2016: 9 · 2015: 7 · 2014: 5
FWCI
1.09
Type
journal article
Language
en
Open access
Locations
  • Clinical Psychology Review (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • CentAUR (University of Reading) (acceptedVersion)
  • Research Portal (King's College London) (submittedVersion)
Funders
  • National Institute for Health Research (NIHR) Mental Health Biomedical Research Centre at South London and Maudsley NHS Foundation Trust
  • King's College London
  • King's Health Partners Academic Health Science Centre
Topics
  • Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
Keywords
self-help intervention, depression, anxiety, psychological distress, physical illness, chronic physical illness, cognitive behavioral therapy, stress management
MeSH terms
Anxiety, Depression, Humans, Psychotherapy, Self Care, Stress, Psychological

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