Self-help interventions for symptoms of depression, anxiety and psychological distress in patients with physical illnesses: A systematic review and meta-analysis
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Psychological distress, depression and anxiety are common in most physical diseases, and self-help interventions, if effective, might be an important approach to improve outcomes as they are inexpensive to provide to large numbers of patients. The primary aim of this review was to assess randomised controlled trials examining the impact of self-help interventions on symptoms of depression, anxiety and psychological distress in patients with physical illness. Systematic searches of electronic databases resulted in twenty-five eligible studies for meta-analysis (n=4211). The results of the primary meta-analyses revealed a significant improvement in depression symptoms, in favour of the intervention group (SMD=-0.13, 95% CI: -0.25, -0.02, p=0.02, I(2)=50%). There were no significant differences in symptoms of anxiety (SMD=-0.10, 95% CI: -0.24, 0.05, p=0.20, I(2)=63%) or psychological distress (SMD=-0.14, 95% CI: -0.40, 0.12, p=0.30, I(2)=72%) between intervention and control conditions. Several subgroup and sensitivity analyses improved effect sizes, suggesting that optimal mental health outcomes may be obtained in patients without neurological conditions, and with interventions based on a therapeutic model (such as cognitive behavioural therapy), and with stress management components. This review demonstrates that with appropriate design and implementation, self-help interventions may potentially improve symptoms of depression in patients with physical conditions.
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A number of reviews demonstrate that self-help interventions are effective for depression and anxiety in adults.
“A number of reviews demonstrate that self-help interventions are effective for depression and anxiety in adults.21,22”
From Comparative efficacy and acceptability of bibliotherapy for depression and anxiety disorders in children and adolescents: a meta-analysis of randomized clinical trials (2018) · cites this paper as [21]
The Discussion reports a small significant benefit for depression, but no significant overall benefit for anxiety. The Conclusions say theoretically based self-help materials may modestly improve both outcomes in patients with physical illness. That cautious, population-specific finding does not establish effectiveness for depression and anxiety in adults generally. (LLM, conf=0.88)
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“These computer-assisted programs are intended to limit the amount of contact time with a mental health professional [21-23].”
- Authors
- Matcham, F., Rayner, L., Hutton, J., Monk, A., Steel, C., & Hotopf, M.
- Affiliations
- King's College London (GB)
- South London and Maudsley NHS Foundation Trust (GB)
- Corresponding author
- Matcham, F.
- Venue
- Clinical Psychology Review
- Publisher
- Elsevier BV
- Published
- 2014-03
- Volume
- 34
- Issue
- 2
- Pages
- 141-157
- ISSN
- 0272-7358 (ISSN-L)
- OpenAlex
- W1988661281
- Cited by
- 85
- References
- 19
- Citations by year
- 2026: 2 · 2025: 6 · 2024: 7 · 2023: 8 · 2022: 10 · 2021: 5 · 2020: 5 · 2019: 6 · 2018: 9 · 2017: 6 · 2016: 9 · 2015: 7 · 2014: 5
- FWCI
- 1.09
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Clinical Psychology Review (publishedVersion, cc-by)
- PubMed (publishedVersion)
- CentAUR (University of Reading) (acceptedVersion)
- Research Portal (King's College London) (submittedVersion)
- Funders
- National Institute for Health Research (NIHR) Mental Health Biomedical Research Centre at South London and Maudsley NHS Foundation Trust
- King's College London
- King's Health Partners Academic Health Science Centre
- Topics
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Keywords
- self-help intervention, depression, anxiety, psychological distress, physical illness, chronic physical illness, cognitive behavioral therapy, stress management
- MeSH terms
- Anxiety, Depression, Humans, Psychotherapy, Self Care, Stress, Psychological
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