Cited by 146Suicide and Self-Harm StudiesAutism Spectrum Disorder ResearchHomicide, Infanticide, and Child Abuse

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Suicidality in autistic youth: A systematic review and meta-analysis

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O'Halloran, L., Coey, P., Wilson, C.·2022·Clinical Psychology Review

DOI 10.1016/j.cpr.2022.102144

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Abstract

Suicidality in autistic youth is a major public health issue. This study aimed to determine global prevalence of, and risk/protective factors for suicidality in autistic youth via systematic review and meta-analysis. We systematically searched Embase, PubMed, PsycINFO, Web of Science, and the Cochrane library for studies from inception to November 22nd, 2021. We selected empirical studies reporting on suicide outcomes (i.e., ideation, behaviors, attempts and deaths) in autistic youth (≤25 years). Random effects models were used to estimate the pooled prevalence of suicide outcomes with 95% confidence interval (CI). Heterogeneity was investigated with potential moderators using meta-regression analyses. The final selection included 47 papers, 29 of which were included in meta-analyses and 37 were narratively synthesized (sociodemographic, psychiatric, psychological, other factors, and interventions). The pooled prevalence of suicidal ideation was 25.2% (95% CI 18.2-33.8; i.e., one in four), suicide attempts 8.3% (3.6-18.2), and suicide deaths 0.2% (0.05-0.52). Estimates in self-reports were higher than in parent-reports. Age was a significant but inconsistent moderator on suicide outcomes, but substantial heterogeneity remained. Adverse childhood experiences were strong risk factors for suicidality, while resilience was protective. Participatory suicide risk-assessment, early intervention, and resilience promotion should be primary clinical/research goals.

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Authors: O'Halloran, L., Coey, P., & Wilson, C.
Affiliations: Children's Health Ireland at Crumlin (IE)
Trinity College Dublin (IE)
ORCID: Coey, P.
Wilson, C.
Venue: Clinical Psychology Review
Publisher: Elsevier BV
Published: 2022-04
Volume: 93
Pages: 102144
ISSN: 0272-7358 (ISSN-L)
DOI: 10.1016/j.cpr.2022.102144
OpenAlex: W4221063598
Cited by: 146
References: 140
Citations by year: 2026: 39 · 2025: 42 · 2024: 38 · 2023: 19 · 2022: 8
FWCI: 4.47
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
creativecommons.org/licenses/by/4.0/ (vor)
Locations: Clinical Psychology Review (publishedVersion, cc-by)
PubMed (publishedVersion)
Topics: Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
Social Sciences › Sociology and Political Science › Homicide, Infanticide, and Child Abuse
Keywords: suicidality, autism spectrum disorder, autistic youth, suicidal ideation, suicide attempts, suicide mortality, prevalence, risk factors, protective factors, adverse childhood experiences, resilience, suicide risk assessment, early intervention, self-report versus parent report
MeSH terms: Adolescent, Autistic Disorder, Humans, Suicide, Suicide, Attempted, Prevalence, Suicidal Ideation

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Suicidality in autistic youth: A systematic review and meta-analysis

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