The DOI matches its Crossref record; 135 of the 140 references it cites were found in a registry or an index, and 3 are not checked yet.
Suicidality in autistic youth: A systematic review and meta-analysis
Open accessAbstract
Suicidality in autistic youth is a major public health issue. This study aimed to determine global prevalence of, and risk/protective factors for suicidality in autistic youth via systematic review and meta-analysis. We systematically searched Embase, PubMed, PsycINFO, Web of Science, and the Cochrane library for studies from inception to November 22nd, 2021. We selected empirical studies reporting on suicide outcomes (i.e., ideation, behaviors, attempts and deaths) in autistic youth (≤25 years). Random effects models were used to estimate the pooled prevalence of suicide outcomes with 95% confidence interval (CI). Heterogeneity was investigated with potential moderators using meta-regression analyses. The final selection included 47 papers, 29 of which were included in meta-analyses and 37 were narratively synthesized (sociodemographic, psychiatric, psychological, other factors, and interventions). The pooled prevalence of suicidal ideation was 25.2% (95% CI 18.2-33.8; i.e., one in four), suicide attempts 8.3% (3.6-18.2), and suicide deaths 0.2% (0.05-0.52). Estimates in self-reports were higher than in parent-reports. Age was a significant but inconsistent moderator on suicide outcomes, but substantial heterogeneity remained. Adverse childhood experiences were strong risk factors for suicidality, while resilience was protective. Participatory suicide risk-assessment, early intervention, and resilience promotion should be primary clinical/research goals.
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“O’Halloran et al. (2022) found an 8.3% prevalence (95% CI: 3.6–18.2%) of suicidal behavior in autistic youth.”
From Risk and Protective Factors of Self-harm and Suicidality in Adolescents: An Umbrella Review with Meta-Analysis (2024) · cites this paper as O’Halloran et al. (2022)
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“O’halloran et al. (2022)‘s review of 22 studies found a pooled 25.2% (95% CI 18.2–33.8) prevalence of suicidal ideation in autistic youth.”
From Risk and Protective Factors of Self-harm and Suicidality in Adolescents: An Umbrella Review with Meta-Analysis (2024) · cites this paper as O’halloran et al. (2022)
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1 retracted
Christensen, D. L., Braun, K. V. N., Baio, J., Bilder, D., Charles, J., Constantino, J. N., Daniels, J., Durkin, M. S., Fitzgerald, R. T., Kurzius-Spencer, M., et al. (2018) · MMWR. Surveillance Summaries · doi:10.15585/mmwr.ss6513a1 · Cited by 587
RetractedBias in meta-analysis detected by a simple, graphical test
Egger, M., Smith, G. D., Schneider, M., & Minder, C. (1997) · BMJ · doi:10.1136/bmj.315.7109.629 · Cited by 56,722
Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & the PRISMA Group* (2009) · Annals of Internal Medicine · doi:10.7326/0003-4819-151-4-200908180-00135 · Cited by 37,554
(2014) · Medical Entomology and Zoology · Cited by 17,633
Stang, A. (2010) · European Journal of Epidemiology · doi:10.1007/s10654-010-9491-z · Cited by 17,396
Borenstein, M., Hedges, L. V., Higgins, J. P. T., & Rothstein, H. R. (2009) · doi:10.1002/9780470743386 · Cited by 14,225
The weirdest people in the world?
Henrich, J., Heine, S. J., & Norenzayan, A. (2010) · Behavioral and Brain Sciences · doi:10.1017/s0140525x0999152x · Cited by 12,641
A basic introduction to fixed-effect and random-effects models for meta-analysis
Borenstein, M., Hedges, L. V., Higgins, J. P. T., & Rothstein, H. R. (2010) · Research Synthesis Methods · doi:10.1002/jrsm.12 · Cited by 6,793
The interpersonal theory of suicide.
Van Orden, K. A., Witte, T. K., Cukrowicz, K. C., Braithwaite, S. R., Selby, E. A., & Joiner, T. E. (2010) · Psychological Review · doi:10.1037/a0018697 · Cited by 5,292
Simonoff, E., Pickles, A., Charman, T., Chandler, S., Loucas, T., & Baird, G. (2008) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/chi.0b013e318179964f · Cited by 3,399
Cited by
Sorted by citations
Autism Spectrum Disorder: A Review
Hirota, T., & King, B. H. (2023) · JAMA · doi:10.1001/jama.2022.23661 · Cited by 957
Newell, V., Phillips, L., Jones, C., Townsend, E., Richards, C., & Cassidy, S. (2023) · Molecular Autism · doi:10.1186/s13229-023-00544-7 · Cited by 143
Updated Systematic Review of Suicide in Autism: 2018–2024
Brown, C. M., Newell, V., Sahin, E., & Hedley, D. (2024) · Current Developmental Disorders Reports · doi:10.1007/s40474-024-00308-9 · Cited by 130
Richardson, R., Connell, T., Foster, M., Blamires, J., Keshoor, S., Moir, C., & Zeng, I. S. (2024) · Journal of Youth and Adolescence · doi:10.1007/s10964-024-01969-w · Cited by 105
Mental health challenges faced by autistic people
Lai, M. (2023) · Nature Human Behaviour · doi:10.1038/s41562-023-01718-2 · Cited by 88
Metadata
- Authors
- O'Halloran, L., Coey, P., & Wilson, C.
- Affiliations
- Children's Health Ireland at Crumlin (IE)
- Trinity College Dublin (IE)
- ORCID
- Venue
- Clinical Psychology Review
- Publisher
- Elsevier BV
- Published
- 2022-04
- Volume
- 93
- Pages
- 102144
- ISSN
- 0272-7358 (ISSN-L)
- OpenAlex
- W4221063598
- Cited by
- 146
- References
- 140
- Citations by year
- 2026: 39 · 2025: 42 · 2024: 38 · 2023: 19 · 2022: 8
- FWCI
- 4.47
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Clinical Psychology Review (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Social Sciences › Sociology and Political Science › Homicide, Infanticide, and Child Abuse
- Keywords
- suicidality, autism spectrum disorder, autistic youth, suicidal ideation, suicide attempts, suicide mortality, prevalence, risk factors, protective factors, adverse childhood experiences, resilience, suicide risk assessment, early intervention, self-report versus parent report
- MeSH terms
- Adolescent, Autistic Disorder, Humans, Suicide, Suicide, Attempted, Prevalence, Suicidal Ideation
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