The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
The systemic inflammation-based neutrophil–lymphocyte ratio: Experience in patients with cancer
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Hallmarks of Cancer: The Next Generation
Hanahan, D., & Weinberg, R. A. (2011) · Cell · doi:10.1016/j.cell.2011.02.013 · Cited by 66,590
Early Palliative Care for Patients with Metastatic Non–Small-Cell Lung Cancer
Temel, J. S., Greer, J. A., Muzikansky, A., Gallagher, E. R., Admane, S., Jackson, V. A., Dahlin, C. M., Blinderman, C. D., Jacobsen, J., Pirl, W. F., et al. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa1000678 · Cited by 7,482
Acute-Phase Proteins and Other Systemic Responses to Inflammation
Gabay, C., & Kushner, I. (1999) · New England Journal of Medicine · doi:10.1056/nejm199902113400607 · Cited by 6,734
Zahorec, R. (2001) · Bratislava Medical Journal · doi:10.1007/bf03656390 · Cited by 1,601
Azab, B., Bhatt, V. R., Phookan, J., Murukutla, S., Kohn, N., Terjanian, T., & Widmann, W. D. (2012) · Annals of Surgical Oncology · doi:10.1245/s10434-011-1814-0 · Cited by 565
Teramukai, S., Kitano, T., Kishida, Y., Kawahara, M., Kubota, K., Komuta, K., Minato, K., Mio, T., Fujita, Y., Yonei, T., et al. (2009) · European Journal of Cancer · doi:10.1016/j.ejca.2009.01.023 · Cited by 344
Research works printed but not linked: 65
- Hanahan, 2000, The hallmarks of cancer, Cell, 100, 57, 10.1016/S0092-8674(00)81683-9 · DOI · Paper page
- Roxburgh, 2010, Role of systemic inflammatory response in predicting survival in patients with primary operable cancer, Future Oncology, 6, 149, 10.2217/fon.09.136 · DOI · Paper page
- McMillan, 2012, The systemic inflammation-based Glasgow Prognostic Score: A decade of experience in patients with cancer, Cancer Treatment Reviews
- Walsh, 2005, Neutrophil–lymphocyte ratio as a prognostic factor in colorectal cancer, Journal of Surgical Oncology, 91, 181, 10.1002/jso.20329 · DOI · Paper page
- Schmidt, 2007, Pretreatment levels of peripheral neutrophils and leukocytes as independent predictors of overall survival in patients with american joint committee on cancer stage iv melanoma: results of the EORTC 18951 biochemotherapy trial, Journal of Clinical Oncology, 25, 1562, 10.1200/JCO.2006.09.0274 · DOI · Paper page
- Clarke, 2011, Use of inflammatory markers to guide cancer treatment, Clinical Pharmacology and Therapeutics, 90, 475, 10.1038/clpt.2011.122 · DOI
- Proctor, 2011, A comparison of inflammation-based prognostic scores in patients with cancer. A Glasgow Inflammation Outcome Study, European Journal of Cancer, 47, 2633, 10.1016/j.ejca.2011.03.028 · DOI · Paper page
- Proctor, M.J. Optimization of the systemic inflammation-based Glasgow prognostic score: a Glasgow inflammation outcome study. Cancer, in press.
- Motomura, 2013, Neutrophil–lymphocyte ratio reflects hepatocellular carcinoma recurrence after liver transplantation via inflammatory microenvironment, Journal of Hepatology, 58, 58, 10.1016/j.jhep.2012.08.017 · DOI · Paper page
- Kantola, 2012, Stage-dependent alterations of the serum cytokine pattern in colorectal carcinoma, British Journal of Cancer, 107, 1729, 10.1038/bjc.2012.456 · DOI
- Proctor, 2012, A derived neutrophil to lymphocyte ratio predicts survival in patients with cancer, British Journal of Cancer, 107, 695, 10.1038/bjc.2012.292 · DOI · Paper page
- Ding, 2010, Elevated preoperative neutrophil to lymphocyte ratio predicts risk of recurrence following curative resection for stage IIA colon cancer, International Journal of Colorectal Disease, 25, 1427, 10.1007/s00384-010-1052-0 · DOI · Paper page
- Kwon, 2012, Clinical significance of preoperative neutrophil–lymphocyte versus platelet–lymphocyte ratio in patients with operable colorectal cancer, Biomarkers, 17, 216, 10.3109/1354750X.2012.656705 · DOI · Paper page
- Neal, 2011, Preoperative systemic inflammation and infectious complications after resection of colorectal liver metastases, Archives of Surgery, 146, 471, 10.1001/archsurg.2011.50 · doi:10.1001/archsurg.2011.50
- Leitch, 2007, Comparison of the prognostic value of selected markers of the systemic inflammatory response in patients with colorectal cancer, British Journal of Cancer, 97, 1266, 10.1038/sj.bjc.6604027 · DOI · Paper page
- Mallappa, 2012, Preoperative neutrophil lymphocyte ratio greater than five is a prognostic factor for recurrent colorectal cancer, Colorectal Disease, 323
- Halazun, 2008, Elevated preoperative neutrophil to lymphocyte ratio predicts survival following hepatic resection for colorectal liver metastases, European Journal of Surgical Oncology, 34, 55, 10.1016/j.ejso.2007.02.014 · DOI · Paper page
- Gomez, 2008, Surgical technique and systemic inflammation influences long-term disease-free survival following hepatic resection for colorectal metastasis, Journal of Surgical Oncology, 98, 371, 10.1002/jso.21103 · DOI
- Hung, 2011, Effect of preoperative neutrophil–lymphocyte ratio on the surgical outcomes of stage II colon cancer patients who do not receive adjuvant chemotherapy, International Journal of Colorectal Disease, 26, 1059, 10.1007/s00384-011-1192-x · DOI
- Chiang, 2012, Can neutrophil-to-lymphocyte ratio predict the survival of colorectal cancer patients who have received curative surgery electively?, International Journal of Colorectal Disease, 1
- Ubukata, 2010, Evaluations of interferon-gamma/interleukin-4 ratio and neutrophil/lymphocyte ratio as prognostic indicators in gastric cancer patients, Journal of Surgical Oncology, 102, 742, 10.1002/jso.21725 · DOI
- Aizawa, 2011, Predictive value of baseline neutrophil/lymphocyte ratio for T4 disease in wall-penetrating gastric cancer, World Journal of Surgery, 35, 2717, 10.1007/s00268-011-1269-2 · DOI
- Jung, 2011, Elevated preoperative neutrophil to lymphocyte ratio predicts poor survival following resection in late stage gastric cancer, Journal of Surgical Oncology, 104, 504, 10.1002/jso.21986 · DOI
- Rashid, 2010, A pre-operative elevated neutrophil: lymphocyte ratio does not predict survival from oesophageal cancer resection, World Journal of Surgical Oncology, 8, 1, 10.1186/1477-7819-8-1 · DOI
- Wang, 2012, Comparison of the prognostic value of various preoperative inflammation-based factors in patients with stage III gastric cancer, Tumor Biology, 33, 749, 10.1007/s13277-011-0285-z · DOI
- Mohri, 2010, Prognostic significance of host- and tumor-related factors in patients with gastric cancer, World Journal of Surgery, 34, 285, 10.1007/s00268-009-0302-1 · DOI
- Shimada, 2010, High preoperative neutrophil–lymphocyte ratio predicts poor survival in patients with gastric cancer, Gastric Cancer, 13, 170, 10.1007/s10120-010-0554-3 · DOI · Paper page
- Garcea, 2011, Preoperative neutrophil-to-lymphocyte ratio (NLR) is associated with reduced disease-free survival following curative resection of pancreatic adenocarcinoma, World Journal of Surgery, 35, 868, 10.1007/s00268-011-0984-z · doi:10.1007/s00268-011-0984-z
- Bhatti, 2010, Preoperative hematologic markers as independent predictors of prognosis in resected pancreatic ductal adenocarcinoma: neutrophil–lymphocyte versus platelet–lymphocyte ratio, American Journal of Surgery, 200, 197, 10.1016/j.amjsurg.2009.08.041 · DOI · Paper page
- Smith, 2009, Preoperative platelet–lymphocyte ratio is an independent significant prognostic marker in resected pancreatic ductal adenocarcinoma, American Journal of Surgery, 197, 466, 10.1016/j.amjsurg.2007.12.057 · DOI · Paper page
- Wang, 2012, Comparison of the prognostic values of various inflammation based factors in patients with pancreatic cancer, Tumour Biology, 33, 749, 10.1007/s13277-011-0285-z · DOI
- Gomez, 2008, Impact of systemic inflammation on outcome following resection for intrahepatic cholangiocarcinoma, Journal of Surgical Oncology, 97, 513, 10.1002/jso.21001 · DOI
- Kinoshita, 2012, Comparison of the prognostic value of inflammation-based prognostic scores in patients with hepatocellular carcinoma, British Journal of Cancer, 107, 988, 10.1038/bjc.2012.354 · DOI · Paper page
- Sakai, 2011, A clinical study of the prognostic factors for postoperative early recurrence in patients who underwent complete resection for pulmonary adenocarcinoma, Annals of Thoracic and Cardiovascular Surgery, 17, 539, 10.5761/atcs.oa.11.01660 · DOI
- Sarraf, 2009, Neutrophil/lymphocyte ratio and its association with survival after complete resection in non-small cell lung cancer, Journal of Thoracic and Cardiovascular Surgery, 137, 425, 10.1016/j.jtcvs.2008.05.046 · DOI · Paper page
- Tomita, 2011, Preoperative neutrophil to lymphocyte ratio as a prognostic predictor after curative resection for non-small cell lung cancer, Anticancer Research, 31, 2995
- Tomita, 2012, Elevated preoperative inflammatory markers based on neutrophil-to-lymphocyte ratio and C-reactive protein predict poor survival in resected non-small cell lung cancer, Anticancer Research, 32, 3535
- Hashimoto, 2012, Clinical significance of preoperative peripheral blood neutrophil count in patients with non-metastatic upper urinary tract carcinoma, World Journal of Urology, 10.1016/j.juro.2012.02.714 · doi:10.1016/j.juro.2012.02.714
- Gondo, 2012, Prognostic value of neutrophil-to-lymphocyte ratio and establishment of novel preoperative risk stratification model in bladder cancer patients treated with radical cystectomy, Urology, 79, 1085, 10.1016/j.urology.2011.11.070 · DOI · Paper page
- Ohno, 2012, Pretreatment neutrophil-to-lymphocyte ratio as an independent predictor of recurrence in patients with nonmetastatic renal cell carcinoma, The World Journal of Urology, 10.1016/j.juro.2011.10.026 · DOI
- Ohno, 2012, Followup of neutrophil-to-lymphocyte ratio and recurrence of clear cell renal cell carcinoma, The Journal of Urology, 187, 411, 10.1016/j.juro.2011.10.026 · DOI
- Cho, 2009, Pre-treatment neutrophil to lymphocyte ratio is elevated in epithelial ovarian cancer and predicts survival after treatment, Cancer Immunology, Immunotherapy, 58, 15, 10.1007/s00262-008-0516-3 · DOI · Paper page
- Idowu, 2012, Clinical implication of pretreatment neutrophil to lymphocyte ratio in soft tissue sarcoma, Biomarkers, 17, 539, 10.3109/1354750X.2012.699554 · DOI
- Wang, 2011, A scoring model based on neutrophil to lymphocyte ratio predicts recurrence of HBV-associated hepatocellular carcinoma after liver transplantation, PLoS One, 6, e25295, 10.1371/journal.pone.0025295 · DOI
- Halazun, 2009, Negative impact of neutrophil–lymphocyte ratio on outcome after liver transplantation for hepatocellular carcinoma, Annals of Surgery, 250, 141, 10.1097/SLA.0b013e3181a77e59 · DOI · Paper page
- Bertuzzo, 2011, Analysis of factors affecting recurrence of hepatocellular carcinoma after liver transplantation with a special focus on inflammation markers, Transplantation, 91, 1279, 10.1097/TP.0b013e3182187cf0 · DOI
- Sato, 2012, Correlation between the pretherapeutic neutrophil to lymphocyte ratio and the pathologic response to neoadjuvant chemotherapy in patients with advanced esophageal cancer, World Journal of Surgery, 36, 617, 10.1007/s00268-011-1411-1 · DOI · Paper page
- Miyata, 2011, Prognostic value of an inflammation-based score in patients undergoing pre-operative chemotherapy followed by surgery for esophageal cancer, Experimental Therapeutics and Medicine, 2, 879, 10.3892/etm.2011.308 · DOI
- Sharaiha, 2011, Elevated preoperative neutrophil:lymphocyte ratio as a predictor of postoperative disease recurrence in esophageal cancer, Annals of Surgical Oncology, 18, 3362, 10.1245/s10434-011-1754-8 · DOI · Paper page
- Carruthers, 2012, Systemic inflammatory response is a predictor of outcome in patients undergoing preoperative chemoradiation for locally advanced rectal cancer, Colorectal Disease, 14, e701, 10.1111/j.1463-1318.2012.03147.x · DOI
- Chua, 2012, Inflammatory markers in blood and serum tumor markers predict survival in patients with epithelial appendiceal neoplasms undergoing surgical cytoreduction and intraperitoneal chemotherapy, Annals of Surgery, 256, 342, 10.1097/SLA.0b013e3182602ad2 · doi:10.1097/sla.0b013e3182602ad2
- Kishi, 2009, Blood neutrophil-to-lymphocyte ratio predicts survival in patients with colorectal liver metastases treated with systemic chemotherapy, Annals of Surgical Oncology, 16, 614, 10.1245/s10434-008-0267-6 · DOI · Paper page
- Cedres, 2012, Neutrophil to lymphocyte ratio (NLR) as an indicator of poor prognosis in stage IV non-small cell lung cancer, Clinical and Translational Oncology, 14, 864, 10.1007/s12094-012-0872-5 · DOI · Paper page
- Kao, 2010, High blood neutrophil-to-lymphocyte ratio is an indicator of poor prognosis in malignant mesothelioma patients undergoing systemic therapy, Clinical Cancer Research, 16, 5805, 10.1158/1078-0432.CCR-10-2245 · DOI · Paper page
- Yao, 2012, Pretreatment neutrophil to lymphocyte ratio is associated with response to therapy and prognosis of advanced non-small cell lung cancer patients treated with first-line platinum-based chemotherapy, Cancer Immunology, Immunotherapy
- Lee, 2012, Early neutrophil-to-lymphocyte ratio reduction as a surrogate marker of prognosis in never smokers with advanced lung adenocarcinoma receiving gefitinib or standard chemotherapy as first-line therapy, Journal of Cancer Research and Clinical Oncology, 138, 2009, 10.1007/s00432-012-1281-4 · DOI
- Aliustaoglu, 2010, The effect of peripheral blood values on prognosis of patients with locally advanced gastric cancer before treatment, Medical Oncology, 27, 1060, 10.1007/s12032-009-9335-4 · DOI
- An, 2010, Elevated neutrophil to lymphocyte ratio predicts survival in advanced pancreatic cancer, Biomarkers, 15, 516, 10.3109/1354750X.2010.491557 · DOI
- Keizman, 2012, The association of pre-treatment neutrophil to lymphocyte ratio with response rate, progression free survival and overall survival of patients treated with sunitinib for metastatic renal cell carcinoma, European Journal of Cancer, 48, 202, 10.1016/j.ejca.2011.09.001 · DOI
- Chua, 2011, Neutrophil/lymphocyte ratio predicts chemotherapy outcomes in patients with advanced colorectal cancer, British Journal of Cancer, 104, 1288, 10.1038/bjc.2011.100 · DOI · Paper page
- Kaneko, 2012, Elevated neutrophil to lymphocyte ratio predicts poor prognosis in advanced colorectal cancer patients receiving oxaliplatin-based chemotherapy, Oncology, 82, 261, 10.1159/000337228 · DOI
- McNally, 2013, Inflammatory markers are associated with outcome in patients with unresectable hepatocellular carcinoma undergoing transarterial chemoembolization, Annals of Surgical Oncology, 20, 923, 10.1245/s10434-012-2639-1 · DOI
- Huang, 2011, Blood neutrophil-to-lymphocyte ratio predicts survival in patients with unresectable hepatocellular carcinoma undergoing transarterial chemoembolization, Journal of Vascular and Interventional Radiology, 22, 702, 10.1016/j.jvir.2010.12.041 · DOI
- Jeong, 2012, Comparison of two inflammation-based prognostic scores in patients with unresectable advanced gastric cancer, Oncology, 83, 292, 10.1159/000342376 · DOI
- Wang, 2011, The neutrophil/lymphocyte ratio is an independent prognostic indicator in patients with bone metastasis, Oncology Letters, 2, 735, 10.3892/ol.2011.304 · DOI
Cited by
Templeton, A. J., McNamara, M. G., Šeruga, B., Vera-Badillo, F. E., Aneja, P., Ocaña, A., Leibowitz-Amit, R., Sonpavde, G., Knox, J. J., Tran, B., et al. (2014) · JNCI: Journal of the National Cancer Institute · doi:10.1093/jnci/dju124 · Cited by 2,829
Cancer-related inflammation and treatment effectiveness
Diakos, C. I., Charles, K. A., McMillan, D. C., & Clarke, S. J. (2014) · The Lancet Oncology · doi:10.1016/s1470-2045(14)70263-3 · Cited by 2,193
Self-citationNeutrophil: A Cell with Many Roles in Inflammation or Several Cell Types?
Rosales, C. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.00113 · Cited by 1,334
Valero, C., Lee, M., Hoen, D., Weiss, K., Kelly, D. W., Adusumilli, P. S., Paik, P. K., Plitas, G., Ladanyi, M., Postow, M. A., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-20935-9 · Cited by 441
Maturation of tertiary lymphoid structures and recurrence of stage II and III colorectal cancer
Posch, F., Silina, K., Leibl, S., Mündlein, A., Moch, H., Siebenhüner, A., Samaras, P., Riedl, J., Stotz, M., Szkandera, J., et al. (2018) · OncoImmunology · doi:10.1080/2162402x.2017.1378844 · Cited by 380
Metadata
- Authors
- Guthrie, G. J. K., Charles, K. A., Roxburgh, C. S. D., Horgan, P. G., McMillan, D. C., & Clarke, S. J.
- Venue
- Critical Reviews in Oncology/Hematology
- Publisher
- Elsevier BV
- Published
- 2013-10
- Volume
- 88
- Issue
- 1
- Pages
- 218-230
- ISSN
- 1040-8428 (ISSN-L)
- OpenAlex
- W2085458222
- Cited by
- 1,552
- References
- 6
- FWCI
- 39.21
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: The systemic inflammation-based neutrophil–lymphocyte ratio: Experience in patients with cancer. https://app.cochat.ai/papers/10.1016/j.critrevonc.2013.03.010
- The paper
- Guthrie, G. J. K., Charles, K. A., Roxburgh, C. S. D., Horgan, P. G., McMillan, D. C., & Clarke, S. J. (2013). The systemic inflammation-based neutrophil–lymphocyte ratio: Experience in patients with cancer. Critical Reviews in Oncology/Hematology. https://doi.org/10.1016/j.critrevonc.2013.03.010
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.