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Cited by 196Cancer Treatment and PharmacologyCancer survivorship and careCancer-related cognitive impairment studies

Effects of exercise on cancer patients suffering chemotherapy-induced peripheral neuropathy undergoing treatment: a systematic review

Duregon, Federica, Vendramin, Barbara, Bullo, Valentina, Gobbo, Stefano, Cugusi, Lucia, Di Blasio, Andrea, Neunhaeuserer, Daniel, Zaccaria, Marco +2 more·2018·Critical Reviews in Oncology/Hematology
DOI 10.1016/j.critrevonc.2017.11.002
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Abstract

Background Chemotherapy-induced peripheral neuropathy (CIPN) is the most common neurological and clinically relevant side effect of many commonly used chemotherapeutic agents. Moreover, little effort has been done to investigate the potentially beneficial effects of specific exercises to counteract the CIPN symptoms.Objective This document aims to summarize and analyze systematically the current body of evidence about the effects of specific exercise protocols on CIPN symptoms, balance control, physical function and quality of life in patients with CIPN.Literature survey Specific terms were identified for the literature research in MEDLINE, Scopus, Bandolier, PEDro, and Web of Science.Methodology Five manuscripts were considered eligible for this review. Quality appraisal distinguished two studies as high quality investigations while three with low quality. Results were summarized in the following domains: "CIPN symptoms", "Static balance control", "Dynamic balance control", "Quality of life and Physical function".Synthesis Significant improvements were detected on postural control. Additionally, patients' quality of life and independence were found ameliorated after exercise sessions. Combined exercise protocols including endurance, strength and sensorimotor training showed larger improvements.Conclusions This systematic review comes from a highly selected but small source of data. Nevertheless, specific exercise for cancer patients undergoing chemotherapy with CIPN symptoms should be recommended since these interventions appeared as feasible and have been demonstrated as useful tools to counteract some of the limitations due to chemotherapy.

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  • In non-cancer populations, there is strong evidence that moderate to vigorous intensity aerobic training is associated with better overall sleep quality.

    “In non-cancer populations, there is strong evidence that moderate to vigorous intensity aerobic training is associated with better overall sleep quality in the general population(54) and there was some evidence showing benefit for specific characteristics of sleep, such as total sleep time, sleep onset latency, and sleep efficiency.”

    From Exercise Guidelines for Cancer Survivors: Consensus Statement from International Multidisciplinary Roundtable (2019) · cites this paper as [54]

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Authors
Duregon, F., Vendramin, B., Bullo, V., Gobbo, S., Cugusi, L., Di Blasio, A., Neunhaeuserer, D., Zaccaria, M., Bergamin, M., & Ermolao, A.
Affiliations
  • University of Padua (IT)
  • University of Cagliari (IT)
Corresponding author
Bergamin, Marco
ORCID
Venue
Critical Reviews in Oncology/Hematology
Publisher
Elsevier BV
Published
2018-01
Volume
121
Pages
90-100
ISSN
1040-8428 (ISSN-L)
DOI
10.1016/j.critrevonc.2017.11.002
OpenAlex
W2767335406
Cited by
196
References
44
Citations by year
2026: 5 · 2025: 16 · 2024: 19 · 2023: 17 · 2022: 25 · 2021: 44 · 2020: 34 · 2019: 28 · 2018: 8
FWCI
2.01
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Critical Reviews in Oncology/Hematology (publishedVersion)
  • PubMed (publishedVersion)
  • UNICA IRIS Institutional Research Information System (University of Cagliari) (submittedVersion)
  • UnissResearch (Università degli Studi di Sassari) (submittedVersion)
  • Padua Research Archive (University of Padova) (submittedVersion)
Topics
  • Health Sciences › Medicine › Oncology › Cancer Treatment and Pharmacology
  • Health Sciences › Medicine › Oncology › Cancer survivorship and care
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cancer-related cognitive impairment studies
Keywords
chemotherapy-induced peripheral neuropathy, exercise therapy, cancer patients, balance control, postural control, quality of life, physical function, sensorimotor training, resistance training, endurance training, chemotherapy side effects
MeSH terms
Antineoplastic Agents, Humans, Neoplasms, Peripheral Nervous System Diseases, Quality of Life, Exercise, Drug-Related Side Effects and Adverse Reactions

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