Complex representation of taste quality by second-order gustatory neurons in Drosophila
Open accessAbstract
Sweet and bitter compounds excite different sensory cells and drive opposing behaviors. However, it remains unclear how sweet and bitter tastes are represented by the neural circuits linking sensation to behavior. To investigate this question in Drosophila, we devised trans-Tango(activity), a strategy for calcium imaging of second-order gustatory projection neurons based on trans-Tango, a genetic transsynaptic tracing technique. We found spatial overlap between the projection neuron populations activated by sweet and bitter tastants. The spatial representation of bitter tastants in the projection neurons was consistent, while that of sweet tastants was heterogeneous. Furthermore, we discovered that bitter tastants evoke responses in the gustatory receptor neurons and projection neurons upon both stimulus onset and offset and that bitter offset and sweet onset excite overlapping second-order projections. These findings demonstrate an unexpected complexity in the representation of sweet and bitter tastants by second-order neurons of the gustatory circuit.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The neurons reached early from gustatory neurons match second-order projection neurons identified by Snell et al. using trans-Tango.
“For instance, the neurons reached early from gustatory neurons (Fig. 6b) match second-order projection neurons identified by Snell et al.86 using trans-Tango.”
From Neuronal wiring diagram of an adult brain (2024) · cites this paper as [86]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Ultrasensitive fluorescent proteins for imaging neuronal activity
Chen, T.-W., Wardill, T. J., Sun, Y., Pulver, S. R., Renninger, S. L., Baohan, A., Schreiter, E. R., Kerr, R. A., Orger, M. B., Jayaraman, V., et al. (2013) · Nature · doi:10.1038/nature12354 · Cited by 6,474 · see citing works
High-performance calcium sensors for imaging activity in neuronal populations and microcompartments
Dana, H., Sun, Y., Mohar, B., Hulse, B. K., Kerlin, A., Hasseman, J. P., Tsegaye, G., Tsang, A., Wong, A. M., Patel, R. H., et al. (2019) · Nature Methods · doi:10.1038/s41592-019-0435-6 · Cited by 1,198 · see citing works
Refinement of Tools for Targeted Gene Expression in Drosophila
Pfeiffer, B. D., Ngo, T.-T. B., Hibbard, K. L., Murphy, C., Jenett, A., Truman, J. W., & Rubin, G. M. (2010) · Genetics · doi:10.1534/genetics.110.119917 · Cited by 1,153 · see citing works
NoRMCorre: An online algorithm for piecewise rigid motion correction of calcium imaging data
Pnevmatikakis, E. A., & Giovannucci, A. (2017) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2017.07.031 · Cited by 1,038 · see citing works
Molecular Architecture of Smell and Taste in Drosophila
Vosshall, L. B., & Stocker, R. F. (2007) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.30.051606.094306 · Cited by 860 · see citing works
Common sense about taste: from mammals to insects
Yarmolinsky, D. A., Zuker, C. S., & Ryba, N. J. P. (2009) · Cell · doi:10.1016/j.cell.2009.10.001 · Cited by 856 · see citing works
CaImAn an open source tool for scalable calcium imaging data analysis
Giovannucci, A., Friedrich, J., Gunn, P., Kalfon, J., Brown, B. L., Koay, S. A., Taxidis, J., Najafi, F., Gauthier, J., Zhou, P., et al. (2019) · eLife · doi:10.7554/elife.38173 · Cited by 827 · see citing works
A chemosensory gene family encoding candidate gustatory and olfactory receptors in Drosophila.
Scott, K., Brady, R., Cravchik, A., Morozov, P., Rzhetsky, A., Zuker, C., & Axel, R. (2001) · Cell · doi:10.1016/s0092-8674(01)00263-x · Cited by 720 · see citing works
Dissecting a circuit for olfactory behaviour in Caenorhabditis elegans
Chalasani, S. H., Chronis, N., Tsunozaki, M., Gray, J. M., Ramot, D., Goodman, M. B., & Bargmann, C. I. (2007) · Nature · doi:10.1038/nature06292 · Cited by 630 · see citing works
Candidate Taste Receptors in Drosophila
Clyne, P. J., Warr, C. G., & Carlson, J. R. (2000) · Science · doi:10.1126/science.287.5459.1830 · Cited by 616 · see citing works
Taste Representations in the Drosophila Brain
Wang, Z., Singhvi, A., Kong, P., & Scott, K. (2004) · Cell · doi:10.1016/j.cell.2004.06.011 · Cited by 489 · see citing works
Two Gr Genes Underlie Sugar Reception in Drosophila
Dahanukar, A. A., Lei, Y.-T., Kwon, J. Y., & Carlson, J. R. (2007) · Neuron · doi:10.1016/j.neuron.2007.10.024 · Cited by 482 · see citing works
Liman, E. R., Zhang, Y. V., & Montell, C. (2014) · Neuron · doi:10.1016/j.neuron.2014.02.022 · Cited by 473 · see citing works
The Molecular and Cellular Basis of Bitter Taste in Drosophila
Weiss, L. A., Dahanukar, A. A., Kwon, J. Y., Banerjee, D., & Carlson, J. R. (2011) · Neuron · doi:10.1016/j.neuron.2011.01.001 · Cited by 441 · see citing works
Taste Perception and Coding in Drosophila
Thorne, N., Chromey, C., Bray, S. M., & Amrein, H. (2004) · Current Biology · doi:10.1016/j.cub.2004.05.019 · Cited by 421 · see citing works
Using translational enhancers to increase transgene expression in Drosophila
Pfeiffer, B. D., Truman, J. W., & Rubin, G. M. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1204520109 · Cited by 397 · see citing works
Imaging Taste Responses in the Fly Brain Reveals a Functional Map of Taste Category and Behavior
Marella, S., Fischler, W., Kong, P., Asgarian, S., Rueckert, E. H., & Scott, K. (2006) · Neuron · doi:10.1016/j.neuron.2005.11.037 · Cited by 380 · see citing works
Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system
Dunipace, L., Meister, S., McNealy, C., & Amrein, H. (2001) · Current Biology · doi:10.1016/s0960-9822(01)00258-5 · Cited by 360 · see citing works
Functions of the ON and OFF channels of the visual system
Schiller, P. H., Sandell, J. H., & Maunsell, J. H. R. (1986) · Nature · doi:10.1038/322824a0 · Cited by 337 · see citing works
Inagaki, H. K., Ben-Tabou de-Leon, S., Wong, A. M., Jagadish, S., Ishimoto, H., Barnea, G., Kitamoto, T., Axel, R., & Anderson, D. J. (2012) · Cell · doi:10.1016/j.cell.2011.12.022 · Cited by 325 · see citing works
Self-citationThe molecular basis for water taste in Drosophila
Cameron, P. A., Hiroi, M., Ngai, J., & Scott, K. (2010) · Nature · doi:10.1038/nature09011 · Cited by 308 · see citing works
The Coding of Temperature in the Drosophila Brain
Gallio, M., Ofstad, T. A., Macpherson, L. J., Wang, J. W., & Zuker, C. S. (2011) · Cell · doi:10.1016/j.cell.2011.01.028 · Cited by 306 · see citing works
The neural mechanisms of gustation: A distributed processing code
Simon, S. A., de Araujo, I. E., Gutierrez, R., & Nicolelis, M. A. L. (2006) · Nature reviews. Neuroscience · doi:10.1038/nrn2006 · Cited by 305 · see citing works
Transsynaptic mapping of second-order taste neurons in flies by trans-Tango
Talay, M., Richman, E. B., Snell, N. J., Hartmann, G. G., Fisher, J. D., Sorkaç, A., Santoyo, J. F., Chou-Freed, C., Nair, N., Johnson, M., et al. (2017) · Neuron · doi:10.1016/j.neuron.2017.10.011 · Cited by 301 · see citing works
Self-citationA Gr receptor is required for response to the sugar trehalose in taste neurons of Drosophila
Dahanukar, A., Foster, K., van der Goes van Naters, W. M., & Carlson, J. R. (2001) · Nature Neuroscience · doi:10.1038/nn765 · Cited by 286 · see citing works
Reproductive ecology of Drosophila
Markow, T. A., & O’Grady, P. (2008) · Functional Ecology · doi:10.1111/j.1365-2435.2008.01457.x · Cited by 280 · see citing works
A Taste Receptor Required for the Caffeine Response In Vivo
Moon, S. J., Köttgen, M., Jiao, Y., Xu, H., & Montell, C. (2006) · Current Biology · doi:10.1016/j.cub.2006.07.024 · Cited by 272 · see citing works
Processing properties of ON and OFF pathways for Drosophila motion detection
Behnia, R., Clark, D. A., Carter, A. G., Clandinin, T. R., & Desplan, C. (2014) · Nature · doi:10.1038/nature13427 · Cited by 262 · see citing works
Genetic Reagents for Making Split-GAL4 Lines in <i>Drosophila</i>
Dionne, H., Hibbard, K. L., Cavallaro, A., Kao, J.-C., & Rubin, G. M. (2018) · Genetics · doi:10.1534/genetics.118.300682 · Cited by 232 · see citing works
Heimbeck, G., Bugnon, V., Gendre, N., Keller, A., & Stocker, R. F. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.011314898 · Cited by 187 · see citing works
A Taste Circuit that Regulates Ingestion by Integrating Food and Hunger Signals
Yapici, N., Cohn, R., Schusterreiter, C., Ruta, V., & Vosshall, L. B. (2016) · Cell · doi:10.1016/j.cell.2016.02.061 · Cited by 162 · see citing works
A complex peripheral code for salt taste in Drosophila
Jaeger, A. H., Stanley, M., Weiss, Z. F., Musso, P.-Y., Chan, R. C., Zhang, H., Feldman-Kiss, D., & Gordon, M. D. (2018) · eLife · doi:10.7554/elife.37167 · Cited by 157 · see citing works
Iggo, A., & Ogawa, H. (1977) · The Journal of Physiology · doi:10.1113/jphysiol.1977.sp011768 · Cited by 152 · see citing works
Neuronal nonlinearity explains greater visual spatial resolution for darks than lights
Kremkow, J., Jin, J., Komban, S. J., Wang, Y., Lashgari, R., Li, X., Jansen, M., Zaidi, Q., & Alonso, J. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1310442111 · Cited by 143 · see citing works
Pain-relief learning in flies, rats, and man: basic research and applied perspectivesPreprint
Gerber, B., Yarali, A., Diegelmann, S., Wotjak, C. T., Pauli, P., & Fendt, M. (2014) · Learning & Memory · doi:10.1101/lm.032995.113 · Cited by 139 · see citing works
Direct Observation of ON and OFF Pathways in the Drosophila Visual System
Strother, J. A., Nern, A., & Reiser, M. B. (2014) · Current Biology · doi:10.1016/j.cub.2014.03.017 · Cited by 136 · see citing works
Representations of taste modality in the Drosophila brain
Harris, D. T., Kallman, B. R., Mullaney, B. C., & Scott, K. (2015) · Neuron · doi:10.1016/j.neuron.2015.05.026 · Cited by 111 · see citing works
GABAergic Projection Neurons Route Selective Olfactory Inputs to Specific Higher-Order Neurons
Liang, L., Li, Y., Potter, C. J., Yizhar, O., Deisseroth, K. A., Tsien, R. W., & Luo, L. (2013) · Neuron · doi:10.1016/j.neuron.2013.06.014 · Cited by 107 · see citing works
Long-range projection neurons in the taste circuit of Drosophila
Kim, H., Kirkhart, C. R., & Scott, K. (2017) · eLife · doi:10.7554/elife.23386 · Cited by 102 · see citing works
Presynaptic gain control drives sweet and bitter taste integration in Drosophila
Chu, B., Chui, V., Mann, K., & Gordon, M. D. (2014) · Current Biology · doi:10.1016/j.cub.2014.07.020 · Cited by 100 · see citing works
Secondary Taste Neurons that Convey Sweet Taste and Starvation in the Drosophila Brain
Kain, P., & Dahanukar, A. A. (2015) · Neuron · doi:10.1016/j.neuron.2015.01.005 · Cited by 83 · see citing works
Consumption of Bitter Alkaloids in Drosophila melanogaster in Multiple-Choice Test Conditions
Sellier, M.-J., Reeb, P., & Marion‐Poll, F. (2010) · Chemical Senses · doi:10.1093/chemse/bjq133 · Cited by 70 · see citing works
Devineni, A. V., Sun, B. L., Zhukovskaya, A., & Axel, R. (2019) · eLife · doi:10.7554/elife.47677 · Cited by 69 · see citing works
Auditory activity is diverse and widespread throughout the central brain of Drosophila
Pacheco, D. A., Thiberge, S. Y., Pnevmatikakis, E., & Murthy, M. (2021) · Nature Neuroscience · doi:10.1038/s41593-020-00743-y · Cited by 66 · see citing works
Mechanisms of lactic acid gustatory attraction in Drosophila
Stanley, M., Ghosh, B., Weiss, Z. F., Christiaanse, J., & Gordon, M. D. (2021) · Current Biology · doi:10.1016/j.cub.2021.06.005 · Cited by 60 · see citing works
Spatiotemporal Coding of Individual Chemicals by the Gustatory System
Reiter, S., Rodriguez, C. C., Sun, K., & Stopfer, M. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.3802-14.2015 · Cited by 56 · see citing works
Musso, P., Junca, P., Jelen, M., Feldman-Kiss, D., Zhang, H., Chan, R. C. W., & Gordon, M. D. (2019) · eLife · doi:10.7554/elife.45636 · Cited by 48 · see citing works
optoPAD, a closed-loop optogenetics system to study the circuit basis of feeding behaviors
Moreira, J.-M., Itskov, P. M., Goldschmidt, D., Baltazar, C., Steck, K., Tastekin, I., Walker, S. J., & Ribeiro, C. (2019) · eLife · doi:10.7554/elife.43924 · Cited by 44 · see citing works
Kvello, P., Jørgensen, K., & Mustaparta, H. (2010) · Journal of Neurophysiology · doi:10.1152/jn.00985.2009 · Cited by 40 · see citing works
Identification of a Single Pair of Interneurons for Bitter Taste Processing in the Drosophila Brain
Bohra, A. A., Kallman, B. R., Reichert, H., & VijayRaghavan, K. (2018) · Current Biology · doi:10.1016/j.cub.2018.01.084 · Cited by 36 · see citing works
Miyazaki, T., Lin, T.-Y., Ito, K., Lee, C.-H., & Stopfer, M. (2015) · Journal of Neurogenetics · doi:10.3109/01677063.2015.1054993 · Cited by 34 · see citing works
Functional Asymmetries in Cockroach ON and OFF Olfactory Receptor Neurons
Burgstaller, M., & Tichy, H. (2010) · Journal of Neurophysiology · doi:10.1152/jn.00785.2010 · Cited by 33 · see citing works
Devineni, A. V., Deere, J. U., Sun, B. L., & Axel, R. (2021) · Current Biology · doi:10.1016/j.cub.2021.10.020 · Cited by 30 · see citing works
Musso, P., Junca, P., Jelen, M., Feldman-Kiss, D., Zhang, H., Chan, R. C. W., & Gordon, M. D. (2019) · eLife · doi:10.7554/elife.45636.042 · Cited by 4 · see citing works
Author response: Long-range projection neurons in the taste circuit of Drosophila
Kim, H., Kirkhart, C., & Scott, K. (2017) · eLife · doi:10.7554/elife.23386.020 · Cited by 3 · see citing works
Moreira, J.-M., Itskov, P. M., Goldschmidt, D., Baltazar, C., Steck, K., Tastekin, I., Walker, S. J., & Ribeiro, C. (2019) · eLife · doi:10.7554/elife.43924.032 · Cited by 1 · see citing works
Flagged first, then by citations
Research works printed but not linked: 1
- [8]Dunipace L, Meister S, Mcnealy C, and Amrein H (2001). Spatially restricted expression of candidate taste receptors in the. Curr. Biol, 822– 835. 11516643
Cited by
Sorted by citations
Neuronal wiring diagram of an adult brain
Dorkenwald, S., Matsliah, A., Sterling, A. R., Schlegel, P., Yu, S.-C., McKellar, C. E., Lin, A., Costa, M., Eichler, K., Yin, Y., et al. (2024) · Nature · doi:10.1038/s41586-024-07558-y · Cited by 570 · see citing works
“6b) match second-order projection neurons identified by Snell et al. 86 using trans -Tango.”
BackgroundMethodSterne, G. R., Otsuna, H., Dickson, B. J., & Scott, K. (2021) · eLife · doi:10.7554/elife.71679 · Cited by 93 · see citing works
A molecular mechanism for high salt taste in Drosophila
McDowell, S. A. T., Stanley, M., & Gordon, M. D. (2022) · Current Biology · doi:10.1016/j.cub.2022.06.012 · Cited by 65 · see citing works
Mechanisms of lactic acid gustatory attraction in Drosophila
Stanley, M., Ghosh, B., Weiss, Z. F., Christiaanse, J., & Gordon, M. D. (2021) · Current Biology · doi:10.1016/j.cub.2021.06.005 · Cited by 60 · see citing works
Descending networks transform command signals into population motor control
Braun, J., Hurtak, F., Wang-Chen, S., & Ramdya, P. (2024) · Nature · doi:10.1038/s41586-024-07523-9 · Cited by 51 · see citing works
Diverse mechanisms of taste coding in Drosophila
Dweck, H. K. M., & Carlson, J. R. (2023) · Science Advances · doi:10.1126/sciadv.adj7032 · Cited by 35 · see citing works
retro-Tango enables versatile retrograde circuit tracing in Drosophila
Sorkaç, A., Moșneanu, R. A., Crown, A. M., Savaş, D., Okoro, A. M., Memiş, E., Talay, M., & Barnea, G. (2023) · eLife · doi:10.7554/elife.85041 · Cited by 35 · see citing works
Self-citationDevineni, A. V., Deere, J. U., Sun, B. L., & Axel, R. (2021) · Current Biology · doi:10.1016/j.cub.2021.10.020 · Cited by 30 · see citing works
Goldschmidt, D., Tastekin, I., Münch, D., Park, J.-Y., Haberkern, H., Serra, L., Baltazar, C., Jayaraman, V., Rubin, G. M., & Ribeiro, C. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.07.19.549514 · Cited by 27 · see citing works
Selective integration of diverse taste inputs within a single taste modality
Deere, J. U., Sarkissian, A. A., Yang, M., Uttley, H. A., Santana, N. M., Nguyen, L., Ravi, K., & Devineni, A. V. (2023) · eLife · doi:10.7554/elife.84856 · Cited by 21 · see citing works
Transsynaptic labeling and transcriptional control of zebrafish neural circuits
Coomer, C. E., Naumova, D., Talay, M., Zolyomi, B., Snell, N. J., Sorkaç, A., Chanchu, J. M., Cheng, J., Roman, I., Li, J., et al. (2024) · Nature Neuroscience · doi:10.1038/s41593-024-01815-z · Cited by 19 · see citing works
Self-citationConnectomic analysis of taste circuits in Drosophila
Walker, S. R., Peña-Garcia, M., & Devineni, A. V. (2025) · Scientific Reports · doi:10.1038/s41598-025-89088-9 · Cited by 18 · see citing works
Li, J., Dhaliwal, R., Stanley, M., Junca, P., & Gordon, M. D. (2025) · Current Biology · doi:10.1016/j.cub.2025.04.035 · Cited by 14 · see citing works
Ehrlich, A., Xu, A. A., Luminari, S., Kidd, S., Treiber, C. D., Russo, J., & Blau, J. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.05.22.595372 · Cited by 11 · see citing works
Transcription factor codes patterning neuronal groundplans of the cerebrum
Elkahlah, N. A., Lin, Y., Pan, Y., Carter, J. A., Shirangi, T. R., & Clowney, E. J. (2026) · Nature · doi:10.1038/s41586-026-10526-3 · Cited by 9 · see citing works
Cavieres-Lepe, J., Amini, E., Zabel, M., Nässel, D. R., Stanewsky, R., Wegener, C., & Ewer, J. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2308067121 · Cited by 9 · see citing works
Circuit analysis reveals a neural pathway for light avoidance in Drosophila larvae
Sorkaç, A., Savva, Y. A., Savaş, D., Talay, M., & Barnea, G. (2022) · Nature Communications · doi:10.1038/s41467-022-33059-5 · Cited by 9 · see citing works
Self-citationTaste cues elicit prolonged modulation of feeding behavior in Drosophila
Deere, J. U., & Devineni, A. V. (2022) · iScience · doi:10.1016/j.isci.2022.105159 · Cited by 8 · see citing works
Feeding decision-making by a single neuron via disparate neurotransmitters
Savaş, D., Okoro, A. M., Moșneanu, R. A., Crown, A. M., Chang, Z., Siegel, R., Sorkaç, A., Zandawala, M., & Barnea, G. (2026) · Nature Communications · doi:10.1038/s41467-026-69443-8 · Cited by 7 · see citing works
Self-citationTaste triggers a homeostatic temperature control in hungry fliesPreprint
Umezaki, Y., Hidalgo, S., Nguyen, E., Nguyen, T. T. M., Suh, J., Uchino, S. S., Chiu, J. C., & Hamada, F. (2024) · eLife · doi:10.7554/elife.94703 · Cited by 5 · see citing works
Mollá-Albaladejo, R., Jiménez-Caballero, M., & Sánchez‐Alcañiz, J. A. (2024) · eLife · doi:10.7554/elife.100947 · Cited by 4 · see citing works
Evolution of taste processing shifts dietary preference
Bertolini, E., Münch, D., Pascual, J., Sgammeglia, N., Bruzzone, M., Ribeiro, C., & Auer, T. O. (2026) · Nature · doi:10.1038/s41586-025-09766-6 · Cited by 3 · see citing works
Eating regulation: How diet impacts food cognition
Yapici, N. (2023) · Current Biology · doi:10.1016/j.cub.2022.12.060 · Cited by 3 · see citing works
Decoding taste perception: the role of electrophysiology in taste transduction mechanisms
Ryu, H. S. (2024) · Korean Intraoperative Neuromonitoring Society · doi:10.54441/jnn.2024.4.2.117 · Cited by 3 · see citing works
Artificial sweeteners differentially activate sweet and bitter gustatory neurons in Drosophila
Arntsen, C., Grenon, J., Chauvel, I., Fraichard, S., Dupas, S., Cortot, J., Audette, K., Musso, P., & Stanley, M. (2025) · Scientific Reports · doi:10.1038/s41598-025-08467-4 · Cited by 3 · see citing works
Regulation of feeding behaviors by key sugar and bitter gustatory receptors in Helicoverpa armigera
Wang, P., Niu, Y., Chen, Y., Zhang, S., Wu, F., Yang, M., Huang, L., Li, C., Xu, C., & Wang, C. (2025) · Pest Management Science · doi:10.1002/ps.8968 · Cited by 2 · see citing works
Castaneda, A. N., Huda, A., Whitaker, I. B. M., Reilly, J. E., Shelby, G. S., Bai, H., & Ni, L. (2024) · PLoS Genetics · doi:10.1371/journal.pgen.1011190 · Cited by 2 · see citing works
Mollá-Albaladejo, R., Jiménez-Caballero, M., & Sánchez‐Alcañiz, J. A. (2025) · eLife · doi:10.7554/elife.100947.3 · Cited by 1 · see citing works
Reward taste conditioning in Drosophila melanogaster
Yang, S., Bae, Y. J., & Masek, P. (2026) · Journal of Experimental Biology · doi:10.1242/jeb.251090 · Cited by 1 · see citing works
Mollá-Albaladejo, R., Jiménez-Caballero, M., & Sánchez‐Alcañiz, J. A. (2024) · eLife · doi:10.7554/elife.100947.1 · Cited by 1 · see citing works
Taste triggers a homeostatic temperature control in hungry flies
Umezaki, Y., Hidalgo, S., Nguyen, E., Nguyen, T. T. M., Suh, J., Uchino, S. S., Chiu, J. C., & Hamada, F. N. (2024) · eLife · doi:10.7554/elife.94703.3
Taste triggers a homeostatic temperature control in DrosophilaPreprint
Umezaki, Y., Hidalgo, S., Nguyen, E., Nguyen, T. T. M., Suh, J., Uchino, S. S., Chiu, J. C., & Hamada, F. N. (2024) · eLife · doi:10.7554/elife.94703.1
Author response: Taste triggers a homeostatic temperature control in hungry flies
Umezaki, Y., Hidalgo, S., Nguyen, E., Nguyen, T. T. M., Suh, J., Uchino, S. S., Chiu, J. C., & Hamada, F. N. (2024) · eLife · doi:10.7554/elife.94703.2.sa0
Taste triggers a homeostatic temperature control in hungry fliesPreprint
Umezaki, Y., Hidalgo, S., Nguyen, E., Nguyen, T. T. M., Suh, J., Uchino, S. S., Chiu, J. C., & Hamada, F. N. (2024) · eLife · doi:10.7554/elife.94703.2
Mollá-Albaladejo, R., Jiménez-Caballero, M., & Sánchez‐Alcañiz, J. A. (2025) · eLife · doi:10.7554/elife.100947.2
Molecular Diversity of Gustatory Receptors in Insects: From Structure to Ecological Adaptation
Xu, R., Zhang, J., Ge, T., & Song, R. (2026) · Archives of Insect Biochemistry and Physiology · doi:10.1002/arch.70142
Transcriptional control of brain sex differentiation in Diptera
Brovkina, M. V., & Clowney, E. J. (2026) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2026.103199
Fisher, J. D., Crown, A. M., Sorkaç, A., Moșneanu, R. A., Martinez-Machado, S., Snell, N. J., Vishwanath, N., Monje, S. J., Vo, A., Wu, A. H., et al. (2026) · Current Biology · doi:10.1016/j.cub.2026.08.003
Self-citation
- Authors
- Snell, N. J., Fisher, J. D., Hartmann, G. G., Zolyomi, B., Talay, M., & Barnea, G.
- Affiliations
- Brown University (US)
- Corresponding author
- Barnea, Gilad
- Venue
- Current Biology
- Publisher
- Elsevier BV
- Published
- 2022-09
- Volume
- 32
- Issue
- 17
- Pages
- 3758-3772.e4
- ISSN
- 0960-9822 (ISSN-L)
- PMC
- PMC9474709
- OpenAlex
- W4291582620
- Cited by
- 39
- References
- 56
- Citations by year
- 2026: 6 · 2025: 7 · 2024: 15 · 2023: 5 · 2022: 3 · 2021: 3
- FWCI
- 3.33
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- www.elsevier.com/open-access/userlicense/1.0/ (vor, 376 d)
- doi.org/10.15223/policy-017 (stm-asf)
- doi.org/10.15223/policy-037 (stm-asf)
- doi.org/10.15223/policy-012 (stm-asf)
- doi.org/10.15223/policy-029 (stm-asf)
- doi.org/10.15223/policy-004 (stm-asf)
- Locations
- Current Biology (publishedVersion)
- bioRxiv (Cold Spring Harbor Laboratory) (acceptedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Science Foundation (1058262)
- Brown University
- National Institutes of Health
- National Institute of Mental Health (R01MH105368, T32MH020068)
- National Institute on Deafness and Other Communication Disorders (R01DC017146)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurobiology and Insect Physiology Research
- Health Sciences › Nursing › Nutrition and Dietetics › Biochemical Analysis and Sensing Techniques
- Life Sciences › Neuroscience › Sensory Systems › Ion Channels and Receptors
- Keywords
- sweet taste, bitter taste, gustatory receptor neurons, transsynaptic tracing, calcium imaging, Drosophila
- MeSH terms
- Animals, Drosophila, Neurons, Taste, Drosophila Proteins, Taste Perception
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
