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Cited by 1,105

The DOI matches its Crossref record; 52 of the 52 references it cites were found in a registry or an index.

State of the art etch-and-rinse adhesives

Open access
Pashley, David H., Tay, Franklin R., Breschi, Lorenzo, Tjäderhane, Leo, Carvalho, Ricardo M., Carrilho, Marcela, Tezvergil-Mutluay, Arzu·2011·Dental Materials
DOI 10.1016/j.dental.2010.10.016
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Abstract

Etch-and-rinse adhesive systems are the oldest of the multi-generation evolution of resin bonding systems. In the 3-step version, they involve acid-etching, priming and application of a separate adhesive. Each step can accomplish multiple goals. This review explores the therapeutic opportunities of each separate step. Acid-etching, using 32-37% phosphoric acid (pH 0.1-0.4) not only simultaneously etches enamel and dentin, but the low pH kills many residual bacteria. Some etchants include anti-microbial compounds such as benzalkonium chloride that also inhibits matrix metalloproteinases (MMPs) in dentin. Primers are usually water and HEMA-rich solutions that ensure complete expansion of the collagen fibril meshwork and wet the collagen with hydrophilic monomers. However, water alone can re-expand dried dentin and can also serve as a vehicle for protease inhibitors or protein cross-linking agents that may increase the durability of resin-dentin bonds. In the future, ethanol or other water-free solvents may serve as dehydrating primers that may also contain antibacterial quaternary ammonium methacrylates to inhibit dentin MMPs and increase the durability of resin-dentin bonds. The complete evaporation of solvents is nearly impossible. Manufacturers may need to optimize solvent concentrations. Solvent-free adhesives can seal resin-dentin interfaces with hydrophobic resins that may also contain fluoride and antimicrobial compounds. Etch-and-rinse adhesives produce higher resin-dentin bonds that are more durable than most 1 and 2-step adhesives. Incorporation of protease inhibitors in etchants and/or cross-linking agents in primers may increase the durability of resin-dentin bonds. The therapeutic potential of etch-and-rinse adhesives has yet to be fully exploited.

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Metadata

Authors
Pashley, D. H., Tay, F. R., Breschi, L., Tjäderhane, L., Carvalho, R. M., Carrilho, M., & Tezvergil-Mutluay, A.
Venue
Dental Materials
Publisher
Elsevier BV
Published
2011-01
Volume
27
Issue
1
Pages
1-16
ISSN
0109-5641 (ISSN-L)
DOI
10.1016/j.dental.2010.10.016
OpenAlex
W2172076806
Cited by
1,105
References
52
FWCI
52.79
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: State of the art etch-and-rinse adhesives. https://app.cochat.ai/papers/10.1016/j.dental.2010.10.016
The paper
Pashley, D. H., Tay, F. R., Breschi, L., Tjäderhane, L., Carvalho, R. M., Carrilho, M., & Tezvergil-Mutluay, A. (2011). State of the art etch-and-rinse adhesives. Dental Materials. https://doi.org/10.1016/j.dental.2010.10.016

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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