Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization

Cassidy-Stone, Ann, Chipuk, Jerry E., Ingerman, Elena, Song, Cheng, Yoo, Choong, Kuwana, Tomomi, Kurth, Mark J., Shaw, Jared T. +3 more·2008·Developmental Cell

Cited by (1,000)

Items 101–200 of 1,000

  1. Regulation of mitochondrial morphology and function by stearoylation of TFR1
    Deniz Senyilmaz, Sam Virtue, Xiaojun Xu, Chong Yew Tan, Julian Leether Griffin, Aubry K. Miller, Antonio Vidal‐Puig, Aurelio A. Teleman · 2015 · Nature
  2. Mitochondrial dysfunction in the development and progression of neurodegenerative diseases
    Joseph Johnson, Elizabeth Mercado‐Ayón, Yesica Mercado-Ayon, Yi Dong, Sarah M. Halawani, Lucie Vanessa Ngaba, David R. Lynch · 2020 · Archives of Biochemistry and Biophysics
  3. Mitochondrial fission/fusion dynamics and apoptosis
    Clare Sheridan, Séamus J. Martin · 2010 · Mitochondrion
  4. Mitochondrial dynamics in the adult cardiomyocytes: which roles for a highly specialized cell?
    Jérôme Piquereau, Fanny Caffin, Marta Novotová, Christophe Lemaire, Vladimir Veksler, Anne Garnier, Renée Ventura‐Clapier, Frédéric Joubert · 2013 · Frontiers in Physiology
  5. Reactive oxygen species regulate Smac mimetic/TNFα-induced necroptotic signaling and cell death
    B Schenk, Simone Fulda · 2015 · Oncogene
  6. Oligodendrocyte death and myelin loss in the cuprizone model: an updated overview of the intrinsic and extrinsic causes of cuprizone demyelination
    Zirngibl, Martin, Assinck, Peggy, Sizov, Anastasia, Caprariello, Andrew V., Plemel, Jason R. · 2022 · Molecular Neurodegeneration
  7. Bcl-xL increases mitochondrial fission, fusion, and biomass in neurons
    Sarah B. Berman, Ying‐Bei Chen, Bing Qi, J. Michael McCaffery, Edmund B. Rucker, Sandra Goebbels, Klaus‐Armin Nave, Beth A. Arnold, Elizabeth Ann Jonas, Fernando J. Pineda et al. · 2009 · The Journal of Cell Biology
  8. Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo
    Phillip M. Rappold, Mei Cui, Jonathan C. Grima, Rebecca Zhangqiuzi Fan, Karen L. de Mesy Bentley, Linan Chen, Xiaoxi Zhuang, William J. Bowers, Kim Tieu · 2014 · Nature Communications
  9. A Chemical Inhibitor of DRP1 Uncouples Mitochondrial Fission and Apoptosis
    Atsushi Tanaka, Richard J. Youle · 2008 · Molecular Cell
  10. Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistance
    Patrizia Romani, Nunzia Nirchio, Mattia Arboit, Vito Barbieri, Anna Tosi, Federica Michielin, Soichi Shibuya, Thomas Benoist, Danchen Wu, Charles C.T. Hindmarch et al. · 2022 · Nature Cell Biology
  11. Mitochondria in cancer
    Debora Grasso, Luca X. Zampieri, Tânia Capelôa, Justine A. Van de Velde, Pierre Sonveaux · 2020 · Cell Stress
  12. SENP3‐mediated deSUMOylation of dynamin‐related protein 1 promotes cell death following ischaemia
    Chun Guo, Keri L. Hildick, Jia Luo, Laura Dearden, Kevin A. Wilkinson, Jeremy Martin Henley · 2013 · The EMBO Journal
  13. Mitochondrial dynamics and their potential as a therapeutic target
    B. N. Whitley, E.A. Engelhart, Suzanne C. Hoppins · 2019 · Mitochondrion
  14. The rheostat in the membrane: BCL-2 family proteins and apoptosis
    Niels Volkmann, Francesca M. Marassi, Donald D. Newmeyer, Dorit Hanein · 2013 · Cell Death and Differentiation
  15. Hippo/Mst signalling couples metabolic state and immune function of CD8α+ dendritic cells
    Xingrong Du, Jing Wen, Yanyan Wang, Peer W. F. Karmaus, Alireza Khatamian, Haiyan Tan, Yuxin Li, Cliff S. Guy, Thanh-Long M. Nguyen, Yogesh Dhungana et al. · 2018 · Nature
  16. Mitochondrial dynamics as regulators of cancer biology
    Andrew Paul Trotta, Jerry E. Chipuk · 2017 · Cellular and Molecular Life Sciences
  17. Dysfunction in endoplasmic reticulum-mitochondria crosstalk underlies SIGMAR1 loss of function mediated motor neuron degeneration
    Nathalie Bernard‐Marissal, Jean‐Jacques Médard, Hamid Azzedine, Roman Chrast · 2015 · Brain
  18. Mitochondrial abnormalities in Parkinson's disease and Alzheimer's disease: can mitochondria be targeted therapeutically?
    Ruby Macdonald, Katy Barnes, Christopher Hastings, Heather Mortiboys · 2018 · Biochemical Society Transactions
  19. Therapeutic potential of targeting mitochondrial dynamics in cancer
    Tiago Rodrigues, Letícia Silva Ferraz · 2020 · Biochemical Pharmacology
  20. Mitochondrial Shape Governs BAX-Induced Membrane Permeabilization and Apoptosis
    Renault, Thibaud T., Floros, Konstantinos V., Elkholi, Rana, Corrigan, Kelly-Ann, Kushnareva, Yulia, Wieder, Shira Y., Lindtner, Claudia, Serasinghe, Madhavika N., Asciolla, James J., Buettner, Christoph et al. · 2015 · Molecular Cell
  21. Arginine Starvation Impairs Mitochondrial Respiratory Function in ASS1-Deficient Breast Cancer Cells
    Fuming Qiu, Yun-Ru Chen, Xiyong Liu, Cheng-Ying Chu, Li‐Jiuan Shen, Jinghong Xu, Shikha Gaur, Henry Jay Forman, Hang Zhang, Shu Sen Zheng et al. · 2014 · Science Signaling
  22. The Role of Mitochondria in Acute Kidney Injury and Chronic Kidney Disease and Its Therapeutic Potential
    Xiaoqin Zhang, Ewud Agborbesong, Xiaogang Li · 2021 · International Journal of Molecular Sciences
  23. Ceapins are a new class of unfolded protein response inhibitors, selectively targeting the ATF6α branch
    Ciara M Gallagher, Carolina Garri, Erica L. Cain, Kenny K. H. Ang, Christopher G. M. Wilson, Steven Chen, Brian R. Hearn, Priyadarshini Jaishankar, Andrés Aranda-Díaz, Michelle R. Arkin et al. · 2016 · eLife
  24. Mitochondrial Reactive Oxygen Species at the Heart of the Matter
    Opher S. Kornfeld, Sunhee Hwang, Marie‐Hélène Disatnik, Che‐Hong Chen, Nir Qvit, Daria Mochly‐Rosen · 2015 · Circulation Research
  25. A small natural molecule promotes mitochondrial fusion through inhibition of the deubiquitinase USP30
    Wen Yue, Ziheng Chen, Hai‐Yang Liu, Yan Chen, Ming Chen, Du Feng, Chaojun Yan, Hao Wu, Lei Du, Yueying Wang et al. · 2014 · Cell Research
  26. Perturbations in Mitochondrial Dynamics Induced by Human Mutant PINK1 Can Be Rescued by the Mitochondrial Division Inhibitor mdivi-1
    Mei Cui, Xiangna Tang, Whitney V. Christian, Yisang Yoon, Kim Tieu · 2010 · Journal of Biological Chemistry
  27. Mitochondria released by cells undergoing TNF-α-induced necroptosis act as danger signals
    Maeda, A, Fadeel, B · 2014 · Cell Death & Disease
  28. Apoptosis Regulation at the Mitochondrial Outer Membrane
    Laura A. Gillies, Tomomi Kuwana · 2013 · Journal of Cellular Biochemistry
  29. Mitochondrial division/mitophagy inhibitor (Mdivi) Ameliorates Pressure Overload Induced Heart Failure
    Srikanth Givvimani, Charu Munjal, Neetu Tyagi, Utpal Sen, Naira S. Metreveli, Suresh C. Tyagi · 2012 · PLoS ONE
  30. Oligodendroglial glycolytic stress triggers inflammasome activation and neuropathology in Alzheimer’s disease
    Zhang, Xinwen, Wang, Rihua, Hu, Di, Sun, Xiaoyan, Fujioka, Hisashi, Lundberg, Kathleen, Chan, Ernest R., Wang, Quanqiu, Xu, Rong, Flanagan, Margaret E. et al. · 2020 · Science Advances
  31. Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis
    Quinten Remijsen, Vera Goossens, Sasker Grootjans, Chris Van den Haute, Nele Vanlangenakker, Yves Dondelinger, Ria Roelandt, Inge Bruggeman, Amanda Costa Gonçalves, Mathieu J.M. Bertrand et al. · 2014 · Cell Death and Disease
  32. The role of Drp1 in mitophagy and cell death in the heart
    Mingming Tong, Daniela Zablocki, Junichi Sadoshima · 2020 · Journal of Molecular and Cellular Cardiology
  33. Mitochondrial hyperfusion induced by loss of the fission protein Drp1 causes ATM-dependent G2/M arrest and aneuploidy through DNA replication stress
    Wei Qian, Serah Choi, Gregory A. Gibson, Simon C. Watkins, Christopher J. Bakkenist, Bennett Van Houten · 2012 · Journal of Cell Science
  34. Mitochondria in the maintenance of hematopoietic stem cells: new perspectives and opportunities
    Marie–Dominique Filippi, Saghi Ghaffari · 2019 · Blood
  35. SUMOylation of the mitochondrial fission protein Drpl occurs at multiple nonconsensus sites within the B domain and is linked to its activity cycle
    Claudia Figueroa‐Romero, Jorge A. Iñiguez-Lluhı́, Julia Stadler, Chuang‐Rung Chang, Damien Arnoult, Peter J. Keller, Yu H. Hong, Craig D. Blackstone, Eva L. Feldman · 2009 · The FASEB Journal
  36. Mitochondrial Dynamics Protein Drp1 Is Overexpressed in Oncocytic Thyroid Tumors and Regulates Cancer Cell Migration
    André Ferreira-da-Silva, Cristina Valacca, Elisabete Rios, Helena Pópulo, Paula Soares, Manuel A. Sobrinho-Simões, Luca Scorrano, Valdemar Máximo, Silvia Campello · 2015 · PLoS ONE
  37. Altered brain energetics induces mitochondrial fission arrest in Alzheimer’s Disease
    Liang Zhang, Sergey Trushin, Trace A. Christensen, Benjamin V. Bachmeier, Benjamin Gateno, Andreas Schroeder, Jia Yao, Kie Itoh, Hiromi Sesaki, Wayne W. Poon et al. · 2016 · Scientific Reports
  38. Mitochondrial dysfunction in sepsis: mechanisms and therapeutic perspectives
    Dongxue Hu, Harshini Sheeja Prabhakaran, Yuan-Yuan Zhang, Gaoxing Luo, Weifeng He, Yih‐Cherng Liou · 2024 · Critical Care
  39. Acidosis overrides oxygen deprivation to maintain mitochondrial function and cell survival
    Mireille Khacho, Michelle Tarabay, David A. Patten, Pamela Khacho, Jason G. MacLaurin, Jennifer Guadagno, Richard Bergeron, Sean P. Cregan, Mary‐Ellen Harper, David S. Park et al. · 2014 · Nature Communications
  40. Emerging Role for Members of the Bcl-2 Family in Mitochondrial Morphogenesis
    Arnaud Autret, Séamus J. Martin · 2009 · Molecular Cell
  41. Mitochondrial Dynamics in Mitochondrial Diseases
    Juan Miguel Suarez-Rivero, Marina Villanueva Paz, Patricia de la Cruz‐Ojeda, Mario de la Mata, David Cotán, Manuel Oropesa-Ávila, Isabel de Lavera, Mónica Álvarez-Córdoba, Raquel Luzón–Hidalgo, José Antonio Sánchez-Alcázar · 2016 · Diseases
  42. Evolving Concepts of Mitochondrial Dynamics
    Gerald W. Dorn · 2018 · Annual Review of Physiology
  43. Dysregulated Mitochondrial Dynamics and Metabolism in Obesity, Diabetes, and Cancer
    Wenting Dai, Lei Jiang · 2019 · Frontiers in Endocrinology
  44. The mitochondrial fission factor dynamin‐related protein 1 modulates T‐cell receptor signalling at the immune synapse
    Francesc Baixauli, Noa Beatriz Martin-Cofreces, Giulia Morlino, Yolanda R. Carrasco, Carmen Calabia-Linares, Esteban Veiga, Juan Manuel Serrador, Francisco Sánchez‐Madrid · 2011 · The EMBO Journal
  45. The ever-growing complexity of the mitochondrial fission machinery
    Alessandro Pagliuso, Pascale Cossart, Fabrizia Stavru · 2017 · Cellular and Molecular Life Sciences
  46. Inhibition of mitochondrial fragmentation protects against Alzheimer’s disease in rodent model
    Wang, Wenzhang, Yin, Jun, Ma, Xiaopin, Zhao, Fanpeng, Siedlak, Sandra L, Wang, Zhenlian, Torres, Sandy, Fujioka, Hisashi, Xu, Ying, Perry, George et al. · 2017 · Human Molecular Genetics
  47. Mitochondrial Fission in Human Diseases
    Madhavika N. Serasinghe, Jerry E. Chipuk · 2016 · Handbook of experimental pharmacology
  48. Inhibition of ERK-DLP1 signaling and mitochondrial division alleviates mitochondrial dysfunction in Alzheimer's disease cybrid cell
    Xueqi Gan, Shengbin Huang, Long Wu, Yongfu Wang, Gang Hu, Guangyue Li, Hongju Zhang, Haiyang Yu, Russell Howard Swerdlow, John Xi Chen et al. · 2013 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  49. Morphological dynamics of mitochondria — A special emphasis on cardiac muscle cells
    Jennifer Hom, Shey‐Shing Sheu · 2009 · Journal of Molecular and Cellular Cardiology
  50. Inhibition of Drp1/Fis1 interaction slows progression of amyotrophic lateral sclerosis
    Amit U. Joshi, Nay Lui Saw, Hannes S. Vogel, Anna D Cunnigham, Mehrdad Shamloo, Daria Mochly‐Rosen · 2018 · EMBO Molecular Medicine
  51. Emerging role of mitophagy in cardiovascular physiology and pathology
    Pablo Esteban Morales, Carla Arias-Durán, Yáreni Ávalos-Guajardo, Geraldine Aedo, Hugo Verdejo, Valentina Parra, Sergio Lavandero · 2019 · Molecular Aspects of Medicine
  52. Mitochondrial quality control in human health and disease
    Bohao Liu, Chen-Zhen Xu, Yi Liu, Zilong Lu, Ting-Lv Fu, Guorui Li, Yu Deng, Guoqing Luo, Song Z. Ding, Ning Li et al. · 2024 · Military Medical Research
  53. Dynamin–Related Protein 1 Deficiency Improves Mitochondrial Fitness and Protects against Progression of Diabetic Nephropathy
    Bernard A. Ayanga, Shawn S. Badal, Yin Wang, Daniel L. Galvan, Benny Hung‐Junn Chang, Paul T. Schumacker, Farhad R. Danesh · 2016 · Journal of the American Society of Nephrology
  54. Helicobacter pylori vacuolating cytotoxin A (VacA) engages the mitochondrial fission machinery to induce host cell death
    Prashant Jain, Zhao‐Qing Luo, Steven R. Blanke · 2011 · Proceedings of the National Academy of Sciences
  55. Titration of mitochondrial fusion rescues <i>Mff</i> -deficient cardiomyopathy
    Chen, Hsiuchen, Ren, Shuxun, Clish, Clary, Jain, Mohit, Mootha, Vamsi, McCaffery, J. Michael, Chan, David C. · 2015 · Journal of Cell Biology
  56. Mitochondria in cell death
    Melissa J. Parsons, Douglas R. Green · 2010 · Essays in Biochemistry
  57. The role of mitochondria in axon development and regeneration
    George M. Smith, Gianluca Gallo · 2017 · Developmental Neurobiology
  58. Mitochondrial division inhibitor 1 reduces dynamin-related protein 1 and mitochondrial fission activity
    Maria Mańczak, Ramesh J. L. Kandimalla, Xiangling Yin, P. Hemachandra Reddy · 2018 · Human Molecular Genetics
  59. Mitochondrial fission induced by platelet-derived growth factor regulates vascular smooth muscle cell bioenergetics and cell proliferation
    Joshua Kuimeta Salabei, Bradford G. Hill · 2013 · Redox Biology
  60. Redox Regulation of Mitochondrial Fission Protein Drp1 by Protein Disulfide Isomerase Limits Endothelial Senescence
    Young-Mee Kim, Seock‐Won Youn, Sudhahar Varadarajan, Archita Das, Reyhaan Chandhri, Henar Cuervo, Junghun Kweon, Silvia Leanhart, Lianying He, Péter T. Tóth et al. · 2018 · Cell Reports
  61. Cardiolipin and Its Different Properties in Mitophagy and Apoptosis
    Xiao-Xiao Li, Bun Tsoi, Yi-Fang Li, Hiroshi Kurihara, Rong‐Rong He · 2015 · Journal of Histochemistry & Cytochemistry
  62. Dynamics of Dynamin-Related Protein 1 in Alzheimer’s Disease and Other Neurodegenerative Diseases
    Darryll Oliver, P. Hemachandra Reddy · 2019 · Cells
  63. BH3 Domains other than Bim and Bid Can Directly Activate Bax/Bak
    Han Du, Jacob Wolf, Blanca Schafer, Tudor Moldoveanu, Jerry E. Chipuk, Tomomi Kuwana · 2010 · Journal of Biological Chemistry
  64. Apoptosis regulation at the mitochondria membrane level
    Shashank Dadsena, Louise E. King, Ana J. García‐Sáez · 2021 · Biochimica et Biophysica Acta (BBA) - Biomembranes
  65. Increased Drp1 promotes autophagy and ESCC progression by mtDNA stress mediated cGAS-STING pathway
    Yujia Li, Hui Chen, Qi Yang, Lixin Wan, Jing Zhao, Yuanyuan Wu, Jiaxin Wang, Yating Yang, Menglan Niu, Hongliang Liu et al. · 2022 · Journal of Experimental & Clinical Cancer Research
  66. LRRK2 impairs PINK1/Parkin-dependent mitophagy via its kinase activity: pathologic insights into Parkinson’s disease
    Bonello, Fiona, Hassoun, Sidi-Mohamed, Mouton-Liger, François, Shin, Yea Seul, Muscat, Adeline, Tesson, Christelle, Lesage, Suzanne, Beart, Philip M, Brice, Alexis, Krupp, Johannes et al. · 2019 · Human Molecular Genetics
  67. Drp1-Mediated Mitochondrial Abnormalities Link to Synaptic Injury in Diabetes Model
    Shengbin Huang, Yongfu Wang, Xueqi Gan, Fang Du, Changjia Zhong, Long Wu, Gang Hu, Alexander A. Sosunov, Guy M. McKhann, Haiyang Yu et al. · 2014 · Diabetes
  68. Mitochondrial dynamics in pulmonary arterial hypertension
    John Jake Ryan, Asish Dasgupta, Jessica Huston, Kuang‐Hueih Chen, Stephen L. Archer · 2015 · Journal of Molecular Medicine
  69. Depletion of mitochondrial fission factor DRP1 causes increased apoptosis in human colon cancer cells
    Akane Inoue‐Yamauchi, Hideaki Oda · 2012 · Biochemical and Biophysical Research Communications
  70. A Small Molecule Promotes Mitochondrial Fusion in Mammalian Cells
    Danling Wang, Jianing Wang, Ghislain M. C. Bonamy, Shelly Meeusen, Richard G. Brusch, Carolina N. Turk, Pengyu Yang, Peter G. Schultz · 2012 · Angewandte Chemie International Edition
  71. Shaping the role of mitochondria in the pathogenesis of Huntington's disease
    Veronica Costa, Luca Scorrano · 2012 · The EMBO Journal
  72. Mitochondrial dynamics in heart disease
    Gerald W. Dorn · 2012 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  73. Glucose Metabolism Drives Histone Acetylation Landscape Transitions that Dictate Muscle Stem Cell Function
    Yucel, Nora, Wang, Yu Xin, Mai, Thach, Porpiglia, Ermelinda, Lund, Peder J., Markov, Glenn, Garcia, Benjamin A., Bendall, Sean C., Angelo, Michael, Blau, Helen M. · 2019 · Cell Reports
  74. Modelling liver cancer initiation with organoids derived from directly reprogrammed human hepatocytes
    Lulu Sun, Yuqing Wang, Jin Cen, Xiaolong Ma, Lei Cui, Zhixin Qiu, Zhengtao Zhang, Hong Li, Run‐Zhou Yang, Chenhua Wang et al. · 2019 · Nature Cell Biology
  75. Altered Mitochondrial Dynamics and TBI Pathophysiology
    Fischer, Tara D., Hylin, Michael J., Zhao, Jing, Moore, Anthony N., Waxham, M. Neal, Dash, Pramod K. · 2016 · Frontiers in Systems Neuroscience
  76. Mitochondrial Dynamics: Biogenesis, Fission, Fusion, and Mitophagy in the Regulation of Stem Cell Behaviors
    Wenyan Fu, Yang Liu, Hang Yin · 2019 · Stem Cells International
  77. Proliferation and fission of peroxisomes — An update
    Michael Schrader, Joseph L. Costello, Luís F. Godinho, Afsoon S. Azadi, Markus Islinger · 2015 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  78. Mitochondrial Dynamics and Mitochondrial Dysfunction in Diabetes.
    Jun Wada, Atsuko Nakatsuka · 2016 · PubMed
  79. Mechanisms of acetaminophen hepatotoxicity and their translation to the human pathophysiology
    Anup Ramachandran, Hartmut Jaeschke · 2017 · Journal of Clinical and Translational Research
  80. Diabetes regulates mitochondrial biogenesis and fission in mouse neurons
    Edwards, J. L., Quattrini, A., Lentz, S. I., Figueroa-Romero, C., Cerri, F., Backus, C., Hong, Y., Feldman, E. L. · 2010 · Diabetologia
  81. Mitochondrial dynamics and cell death in heart failure
    José Marı́n-Garcı́a, Alexander T. Akhmedov · 2016 · Heart Failure Reviews
  82. Mitochondria: the indispensable players in innate immunity and guardians of the inflammatory response
    Abhishek Mohanty, Rashmi Tiwari-Pandey, Nihar R. Pandey · 2019 · Journal of Cell Communication and Signaling
  83. C-Peptide Activates AMPKα and Prevents ROS-Mediated Mitochondrial Fission and Endothelial Apoptosis in Diabetes
    Mahendra Prasad Bhatt, Young‐Cheol Lim, Young‐Myeong Kim, Kwon‐Soo Ha · 2013 · Diabetes
  84. A reciprocal relationship between reactive oxygen species and mitochondrial dynamics in neurodegeneration
    Clara Hiu-Ling Hung, Sally Shuk‐Yee Cheng, Yuen-Ting Cheung, Suthicha Wuwongse, Natalie Qishan Zhang, Janice Yuen Shan Ho, Simon Ming‐Yuen Lee, Raymond Chuen‐Chung Chang · 2017 · Redox Biology
  85. A Futile Battle? Protein Quality Control and the Stress of Aging
    Ryo Higuchi‐Sanabria, Phillip Andrew Frankino, Joseph West Paul, Sarah U. Tronnes, Andrew G. Dillin · 2018 · Developmental Cell
  86. Peroxisome-derived lipids regulate adipose thermogenesis by mediating cold-induced mitochondrial fission
    Hongsuk Park, Anyuan He, Min Tan, Jordan M. Johnson, John M. Dean, Terri Pietka, Yali Chen, Xiangyu Zhang, Fong‐Fu Hsu, Babak Razani et al. · 2018 · Journal of Clinical Investigation
  87. Caenorhabditis elegans drp-1 and fis-2 Regulate Distinct Cell-Death Execution Pathways Downstream of ced-3 and Independent of ced-9
    David G. Breckenridge, Byung‐Ho Kang, David Kokel, Shohei Mitani, L. Andrew Staehelin, Ding Xue · 2008 · Molecular Cell
  88. Mitochondrial contribution to lipofuscin formation
    Jeannette König, Christiane Ott, Martín Hugo, Tobias Jung, Anne‐Laure Bulteau, Tilman Grune, Annika Höhn · 2017 · Redox Biology
  89. Mitochondrial division inhibitor-1 is neuroprotective in the A53T-α-synuclein rat model of Parkinson’s disease
    Simone Bido, Federico Nicolás Soria, Rebecca Zhangqiuzi Fan, Erwan Bézard, Kim Tieu · 2017 · Scientific Reports
  90. The Role of Mitochondrial Dynamics and Mitophagy in Carcinogenesis, Metastasis and Therapy
    Yigang Wang, Huihui Liu, Yuting Cao, Leilei Zhang, Fang Huang, Cong Yi · 2020 · Frontiers in Cell and Developmental Biology
  91. Mitochondrial fission in Huntington's disease mouse striatum disrupts ER-mitochondria contacts leading to disturbances in Ca2+ efflux and Reactive Oxygen Species (ROS) homeostasis
    Marta Cherubini, Laura López-Molina, Sílvia Ginés · 2020 · Neurobiology of Disease
  92. MitophAging: Mitophagy in Aging and Disease
    Daniela Bakula, Morten Scheibye‐Knudsen · 2020 · Frontiers in Cell and Developmental Biology
  93. Mitochondrial fission and fusion dynamics: the long and short of it
    Sarah B. Berman, Fernando J. Pineda, J. Marie Hardwick · 2008 · Cell Death and Differentiation
  94. The regulation of mitochondrial dynamics
    Suzanne C. Hoppins · 2014 · Current Opinion in Cell Biology
  95. Drp1/Fis1 interaction mediates mitochondrial dysfunction, bioenergetic failure and cognitive decline in Alzheimer's disease
    Amit U. Joshi, Nay Lui Saw, Mehrdad Shamloo, Daria Mochly‐Rosen · 2017 · Oncotarget
  96. Andrographolide alleviates Parkinsonism in MPTP‐PD mice via targeting mitochondrial fission mediated by dynamin‐related protein 1
    Ji Geng, Wen Liu, Jian Gao, Chunhong Jiang, Ting Fan, Yang Sun, Zheng‐Hong Qin, Qiang Xu, Wenjie Guo, Jing Gao · 2019 · British Journal of Pharmacology
  97. Mitochondrial Dysfunction and Therapeutic Perspectives in Cardiovascular Diseases
    Yu Liu, Yuejia Huang, Chong Bing Xu, Peng An, Yongting Luo, Lei Jiao, Junjie Luo, Yongzhi Li · 2022 · International Journal of Molecular Sciences
  98. A Selective Inhibitor of Drp1, Mdivi-1, Increases Retinal Ganglion Cell Survival in Acute Ischemic Mouse Retina
    Sang Woo Park, Keun-young Kim A, James D. Lindsey, Yi Ling Dai, Hwan Heo, Duy H. Nguyen, Mark H. Ellisman, Robert Neal Weinreb, Won‐Kyu Ju · 2011 · Investigative Ophthalmology & Visual Science
  99. GDAP1 mutations differ in their effects on mitochondrial dynamics and apoptosis depending on the mode of inheritance
    Axel Niemann, Konstanze Marion Wagner, Marcel Rüegg, Ueli Suter · 2009 · Neurobiology of Disease
  100. Myocardial Ischemia-Reperfusion Injury: Therapeutics from a Mitochondria-Centric Perspective
    Manli Zhou, Yunfeng Yu, Xiaoxin Luo, Jianzhang Wang, Xiaodong Lan, Pei Liu, Yu Feng, Weixiong Jian · 2021 · Cardiology