Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization

Cassidy-Stone, Ann, Chipuk, Jerry E., Ingerman, Elena, Song, Cheng, Yoo, Choong, Kuwana, Tomomi, Kurth, Mark J., Shaw, Jared T. +3 more·2008·Developmental Cell

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  5. Mdivi-1 Protects Adult Rat Hippocampal Neural Stem Cells against Palmitate-Induced Oxidative Stress and Apoptosis
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  27. High content organelle trafficking enables disease state profiling as powerful tool for disease modelling
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  28. Mitochondrial dynamics, quality control, and mtDNA in alcohol-associated liver disease and liver cancer
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  29. Mitochondrial medicine: “from bench to bedside” 3PM-guided concept
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  31. Inside an enigma: do mitochondria contribute to cell death in Drosophila?
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    Dandan Liu, Jiande Li, Xiaoming Rong, Jie Li, Ying Peng, Qingyu Shen · 2022 · Molecular Neurobiology
  50. A mitotic NADPH upsurge promotes chromosome segregation and tumour progression in aneuploid cancer cells
    Aoxing Cheng, Xu Tian, Weiyi You, Ting Wang, Dongming Zhang, Huimin Guo, Haiyan Zhang, Xin Pan, Yucai Wang, Liu Liu et al. · 2023 · Nature Metabolism
  51. Mdivi-1, mitochondrial fission inhibitor, impairs developmental competence and mitochondrial function of embryos and cells in pigs
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  52. Macroautophagy inhibition maintains fragmented mitochondria to foster T cell receptor‐dependent apoptosis
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  75. Mitochondrial Dynamism and Cardiac Fate
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  93. Ca2+ signaling and gene transcription in glucose-stimulated insulinoma cells
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