Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization
Cassidy-Stone, Ann, Chipuk, Jerry E., Ingerman, Elena, Song, Cheng, Yoo, Choong, Kuwana, Tomomi, Kurth, Mark J., Shaw, Jared T. +3 more·2008·Developmental Cell
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- Bax-PGAM5L-Drp1 complex is required for intrinsic apoptosis executionXu Wenjuan, Linlin Jing, Quanshi Wang, Chung‐Chih Lin, Xiaoting Chen, Jianxin Diao, Yuanliang Liu, Xuegang Sun · 2015 · Oncotarget
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- Increased mitochondrial fission and neuronal dysfunction in Huntington's disease: implications for molecular inhibitors of excessive mitochondrial fissionP. Hemachandra Reddy · 2014 · Drug Discovery Today
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- Necroptosis induced by RIPK3 requires MLKL but not Drp1Moujalled, D M, Cook, W D, Murphy, J M, Vaux, D L · 2014 · Cell Death & Disease
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