The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Mapping Gene Expression in Two Xenopus Species: Evolutionary Constraints and Developmental Flexibility
Open accessAbstract
Changes in gene expression are thought to be important for morphological evolution, though little is known about the nature or magnitude of the differences. Here we examine Xenopus laevis and Xenopus tropicalis, two amphibians with very similar development, and ask how their transcriptomes compare. Despite separation for ~30–90 million years there is strong conservation in gene expression in the vast majority of the expressed orthologs. Significant changes occur in the level of gene expression but changes in the timing of expression (heterochrony) were much less common. Differences in level were concentrated in the earliest embryonic stages. Changes in timing were prominently found in pathways that respond to selective features of the environment. We propose that different evolutionary rates across developmental stages may be explained by the stabilization of cell fate determination in the later stages.
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Subramanian, A., Tamayo, P., Mootha, V. K., Mukherjee, S., Ebert, B. L., Gillette, M. A., Paulovich, A., Pomeroy, S. L., Golub, T. R., Lander, E. S., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0506580102 · Cited by 53,625
Mayr, E. (1963) · doi:10.4159/harvard.9780674865327 · Cited by 10,175
King, M.-C., & Wilson, A. C. (1975) · Science · doi:10.1126/science.1090005 · Cited by 2,815
Evolution of primate gene expression
Khaitovich, P., Enard, W., Lachmann, M., & Pääbo, S. (2006) · Nature Reviews Genetics · doi:10.1038/nrg1940 · Cited by 341
Schmidt, M., Gerlach, F., Avivi, A., Laufs, T., Wystub, S., Simpson, J. C., Nevo, E., Saaler-Reinhardt, S., Reuss, S., Hankeln, T., et al. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m310540200 · Cited by 222
Cited by
Genome evolution in the allotetraploid frog Xenopus laevis
Session, A. M., Uno, Y., Kwon, T., Chapman, J. A., Toyoda, A., Takahashi, S., Fukui, A., Hikosaka, A., Suzuki, A., Kondo, M., et al. (2016) · Nature · doi:10.1038/nature19840 · Cited by 949
Panorama of ancient metazoan macromolecular complexes
Wan, C., Borgeson, B., Phanse, S., Tu, F., Drew, K., Clark, G., Xiong, X., Kagan, O., Kwan, J., Bezginov, A., et al. (2015) · Nature · doi:10.1038/nature14877 · Cited by 546
The maternal-to-zygotic transition revisited
Vastenhouw, N. L., Cao, W. X., & Lipshitz, H. D. (2019) · Development · doi:10.1242/dev.161471 · Cited by 445
Lombard‐Banek, C., Moody, S. A., & Nemes, P. (2016) · Angewandte Chemie International Edition · doi:10.1002/anie.201510411 · Cited by 214
Cell-fate determination by ubiquitin-dependent regulation of translation
Werner, A., Iwasaki, S., McGourty, C. A., Medina-Ruiz, S., Teerikorpi, N., Fedrigo, I., Ingolia, N. T., & Rape, M. (2015) · Nature · doi:10.1038/nature14978 · Cited by 184
Metadata
- Authors
- Yanai, I., Peshkin, L., Jorgensen, P., & Kirschner, M. W.
- Venue
- Developmental Cell
- Publisher
- Elsevier BV
- Published
- 2011-04
- Volume
- 20
- Issue
- 4
- Pages
- 483-496
- ISSN
- 1534-5807 (ISSN-L)
- OpenAlex
- W2033588416
- Cited by
- 204
- References
- 5
- FWCI
- 6.58
- Type
- journal article
- Language
- en
- Open access
- bronze
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