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Divergent matrix-remodeling strategies distinguish developmental from neoplastic mammary epithelial cell invasion programs.
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The cytoplasmic tail of MT1-MMP plays an important role in endocytosis of MT1-MMP and the localization of MT1-MMP on specific microdomains in the plasma membrane.
“The cytoplasmic tail of MT1-MMP plays an important role in endocytosis of MT1-MMP and the localization of MT1-MMP on the specific microdomains in the plasma membrane (19, 23–25).”
From Identification of amino acid residues in the MT-loop of MT1-MMP critical for its ability to cleave low-density lipoprotein receptor (2022) · cites this paper as [25]
The Results and Discussion passages address MT1-MMP’s role in collagen remodeling and mammary invasion, not the function of its cytoplasmic tail. Searches for “cytoplasmic tail,” “endocytosis,” and “microdomains” found no passage in our copy connecting the tail to endocytosis or localization at plasma-membrane microdomains; page numbers were unavailable. (LLM, conf=0.76)
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Calvo, F., Ege, N., Grande-Garcia, A., Hooper, S., Jenkins, R. P., Chaudhry, S. I., Harrington, K., Williamson, P., Moeendarbary, E., Charras, G., et al. (2013) · Nature Cell Biology · doi:10.1038/ncb2756 · Cited by 1,478
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Research works printed but not linked: 50
- Ager, 2015, Blockade of MMP14 activity in murine breast carcinomas: implications for macrophages, vessels, and radiotherapy, J. Natl. Cancer Inst., 107, 10.1093/jnci/djv017 · DOI
- Cheung, 2013, Collective invasion in breast cancer requires a conserved basal epithelial program, Cell, 155, 1639, 10.1016/j.cell.2013.11.029 · DOI
- Correia, 2013, The hemopexin domain of MMP3 is responsible for mammary epithelial invasion and morphogenesis through extracellular interaction with HSP90β, Genes Dev., 27, 805, 10.1101/gad.211383.112 · DOI
- Corsa, 2016, The action of discoidin domain Receptor 2 in basal tumor cells and stromal cancer-associated fibroblasts is critical for breast cancer metastasis, Cell Rep., 15, 2510, 10.1016/j.celrep.2016.05.033 · DOI
- Devy, 2009, Selective inhibition of matrix metalloproteinase-14 blocks tumor growth, invasion, and angiogenesis, Cancer Res., 69, 1517, 10.1158/0008-5472.CAN-08-3255 · DOI
- Edgar, 2002, Gene Expression Omnibus: NCBI gene expression and hybridization array data repository, Nucleic Acids Res., 30, 207, 10.1093/nar/30.1.207 · DOI · Paper page
- Feinberg, 2016, Functional roles of MMP14 and MMP15 in early postnatal mammary gland development, Development, 143, 3956, 10.1242/dev.136259 · DOI
- Fingleton, 2008, MMPs as therapeutic targets–still a viable option?, Semin Cell Dev. Biol., 19, 61, 10.1016/j.semcdb.2007.06.006 · DOI
- Fischer, 2015, Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance, Nature, 527, 472, 10.1038/nature15748 · DOI · Paper page
- Gutiérrez-Fernández, 2015, Loss of MT1-MMP causes cell senescence and nuclear defects which can be reversed by retinoic acid, EMBO J., 34, 1875, 10.15252/embj.201490594 · DOI · Paper page
- Halaoui, 2017, Progressive polarity loss and luminal collapse disrupt tissue organization in carcinoma, Genes Dev., 31, 1573, 10.1101/gad.300566.117 · DOI
- Harper, 2016, Mechanism of early dissemination and metastasis in Her2+ mammary cancer, Nature, 540, 552, 10.1038/nature20609 · DOI
- Hosseini, 2016, Early dissemination seeds metastasis in breast cancer, Nature, 540, 552, 10.1038/nature20785 · DOI
- Hwang, 2017, In situ imaging of tissue remodeling with collagen hybridizing peptides, ACS Nano, 11, 9825, 10.1021/acsnano.7b03150 · DOI
- Inman, 2015, Mammary gland development: cell fate specification, stem cells and the microenvironment, Development, 142, 1028, 10.1242/dev.087643 · DOI
- Irizarry, 2003, Exploration, normalization, and summaries of high density oligonucleotide array probe level data, Biostatistics, 4, 249, 10.1093/biostatistics/4.2.249 · DOI · Paper page
- Kai, 2016, Force matters: biomechanical regulation of cell invasion and migration in disease, Trends Cell Biol., 26, 486, 10.1016/j.tcb.2016.03.007 · DOI
- Khokha, 2011, Mammary gland reprogramming: metalloproteinases couple form with function, Cold Spring Harb. Perspect. Biol., 3, 10.1101/cshperspect.a004333 · DOI
- Koledova, 2016, SPRY1 regulates mammary epithelial morphogenesis by modulating EGFR-dependent stromal paracrine signaling and ECM remodeling, Proc. Natl. Acad. Sci. USA, 113, E5731, 10.1073/pnas.1611532113 · DOI
- Lambert, 2017, Emerging biological principles of metastasis, Cell, 168, 670, 10.1016/j.cell.2016.11.037 · DOI
- Li, 2012, Targeting collagen strands by photo-triggered triple-helix hybridization, Proc. Natl. Acad. Sci. USA, 109, 14767, 10.1073/pnas.1209721109 · DOI
- Liu, 1995, A targeted mutation at the known collagenase cleavage site in mouse type I collagen impairs tissue remodeling, J. Cell Biol., 130, 227, 10.1083/jcb.130.1.227 · DOI
- Liu, 2015, Confinement and low adhesion induce fast amoeboid migration of slow mesenchymal cells, Cell, 160, 659, 10.1016/j.cell.2015.01.007 · DOI
- Lodillinsky, 2016, p63/MT1-MMP axis is required for in situ to invasive transition in basal-like breast cancer, Oncogene, 35, 344, 10.1038/onc.2015.87 · DOI
- Loganathan, 2016, Extracellular matrix motion and early morphogenesis, Development, 143, 2056, 10.1242/dev.127886 · DOI
- Lu, 2008, Genetic mosaic analysis reveals FGF receptor 2 function in terminal end buds during mammary gland branching morphogenesis, Dev. Biol., 321, 77, 10.1016/j.ydbio.2008.06.005 · DOI
- Mori, 2013, Transmembrane/`cytoplasmic, rather than catalytic, domains of Mmp14 signal to MAPK activation and mammary branching morphogenesis via binding to integrin beta1, Development, 140, 343, 10.1242/dev.084236 · DOI · Paper page
- Nelson, 2006, Tissue geometry determines sites of mammary branching morphogenesis in organotypic cultures, Science, 314, 298, 10.1126/science.1131000 · DOI
- Nguyen-Ngoc, 2012, ECM microenvironment regulates collective migration and local dissemination in normal and malignant mammary epithelium, Proc. Natl. Acad. Sci. USA, 109, E2595, 10.1073/pnas.1212834109 · DOI
- Ni, 2016, Snail1-dependent p53 repression regulates expansion and activity of tumour-initiating cells in breast cancer, Nat. Cell Biol., 18, 1221, 10.1038/ncb3425 · DOI
- Paul, 2017, Cancer cell motility: lessons from migration in confined spaces, Nat. Rev. Cancer, 17, 131, 10.1038/nrc.2016.123 · DOI
- Peng, 2016, Myeloid-derived suppressor cells endow stem-like qualities to breast cancer cells through IL6/STAT3 and NO/NOTCH cross-talk signaling, Cancer Res., 76, 3156, 10.1158/0008-5472.CAN-15-2528 · DOI
- Piotrowski-Daspit, 2017, Dynamics of tissue-induced alignment of fibrous extracellular matrix, Biophys. J., 113, 702, 10.1016/j.bpj.2017.06.046 · DOI
- Rebustini, 2009, MT2-MMP-dependent release of collagen IV NC1 domains regulates submandibular gland branching morphogenesis, Dev. Cell, 17, 482, 10.1016/j.devcel.2009.07.016 · DOI
- Robinson, 2007, Cooperation of signalling pathways in embryonic mammary gland development, Nat. Rev. Genet., 8, 963, 10.1038/nrg2227 · DOI
- Rossé, 2014, Control of MT1-MMP transport by atypical PKC during breast-cancer progression, Proc. Natl. Acad. Sci. USA, 111, E1872, 10.1073/pnas.1400749111 · DOI
- Rowe, 2009, Navigating ECM barriers at the invasive front: the cancer cell-stroma interface, Annu. Rev. Cell Dev. Biol., 25, 567, 10.1146/annurev.cellbio.24.110707.175315 · DOI
- Sabeh, 2009, Protease-dependent versus -independent cancer cell invasion programs: three-dimensional amoeboid movement revisited, J. Cell Biol., 185, 11, 10.1083/jcb.200807195 · DOI
- Sharon, 2013, Isolation of normal and cancer-associated fibroblasts from fresh tissues by fluorescence activated cell sorting (FACS), J. Vis. Exp, e4425
- Shimizu-Hirota, 2012, MT1-MMP regulates the PI3Kδ.Mi-2/NuRD-dependent control of macrophage immune function, Genes Dev., 26, 395, 10.1101/gad.178749.111 · DOI
- Simian, 2001, The interplay of matrix metalloproteinases, morphogens and growth factors is necessary for branching of mammary epithelial cells, Development, 128, 3117, 10.1242/dev.128.16.3117 · DOI
- Tang, 2013, MT1-MMP-dependent control of skeletal stem cell commitment via a beta1-integrin/YAP/TAZ signaling axis, Dev. Cell, 25, 402, 10.1016/j.devcel.2013.04.011 · DOI
- Trimboli, 2009, Pten in stromal fibroblasts suppresses mammary epithelial tumours, Nature, 461, 1084, 10.1038/nature08486 · DOI
- Wagner, 2001, Spatial and temporal expression of the Cre gene under the control of the MMTV-LTR in different lines of transgenic mice, Transgenic Res., 10, 545, 10.1023/A:1013063514007 · DOI
- Wang, 2017, Patterned cell and matrix dynamics in branching morphogenesis, J. Cell Biol., 216, 559, 10.1083/jcb.201610048 · DOI
- Wculek, 2015, Neutrophils support lung colonization of metastasis-initiating breast cancer cells, Nature, 528, 413, 10.1038/nature16140 · DOI
- Welm, 2008, Lentiviral transduction of mammary stem cells for analysis of gene function during development and cancer, Cell Stem Cell, 2, 90, 10.1016/j.stem.2007.10.002 · DOI
- Williams, 1983, Mammary ductal elongation: differentiation of myoepithelium and basal lamina during branching morphogenesis, Dev. Biol., 97, 274, 10.1016/0012-1606(83)90086-6 · DOI
- Ye, 2015, Distinct EMT programs control normal mammary stem cells and tumour-initiating cells, Nature, 525, 256, 10.1038/nature14897 · DOI
- Zheng, 2002, Ligand-dependent genetic recombination in fibroblasts: a potentially powerful technique for investigating gene function in fibrosis, Am. J. Pathol., 160, 1609, 10.1016/S0002-9440(10)61108-X · DOI
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Zhu, L., Tang, Y., Li, X.-Y., Keller, E. T., Yang, J., Cho, J.-S., Feinberg, T. Y., & Weiss, S. J. (2020) · Science Translational Medicine · doi:10.1126/scitranslmed.aaw6143 · Cited by 178
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Gonzalez-Molina, J., Gramolelli, S., Liao, Z., Carlson, J. W., Ojala, P. M., & Lehti, K. (2019) · Cells · doi:10.3390/cells8090991 · Cited by 89
Alabi, A., Xia, X.-D., Gu, H.-M., Wang, F., Deng, S.-J., Yang, N., Adijiang, A., Douglas, D. N., Kneteman, N. M., Xue, Y., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-22167-3 · Cited by 63
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Metadata
- Authors
- Feinberg, T. Y., Zheng, H., Liu, R., Wicha, M. S., Yu, S. M., & Weiss, S. J.
- Venue
- Developmental Cell
- Publisher
- Elsevier BV
- Published
- 2018-10
- Volume
- 47
- Issue
- 2
- Pages
- 145-160.e6
- ISSN
- 1534-5807
- PMC
- PMC6317358
- Cited by
- 78
- References
- 1
- Language
- en
- Licence
- Funders
- NIH (RO1AR060484)
- NIDDK
- University of Utah
- University of Michigan
- NCI (CA071699)
- DOD (W81XWH-12-1-0555)
- Breast Cancer Research Foundation
- University of Michigan Rogel Cancer Center Support (P30 CA046592)
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