Cited by 58Diabetes Management and ResearchDiabetes and associated disordersDiabetes Management and Education

Long-term and recent trends in survival and life expectancy for people with type 1 diabetes in Finland

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Arffman, Martti, Hakkarainen, Pirjo, Keskimäki, Ilmo, Oksanen, Tuula, Sund, Reijo·2023·Diabetes Research and Clinical Practice

Abstract

AIMS: Type 1 diabetes has been associated with a significant reduction in life expectancy. Major advances in treatment of type 1 diabetes have been associated with improved survival. However, life expectancy for type 1 diabetes under contemporary care is not known. METHODS: Health care registers were used to obtain data on all people with type 1 diabetes in Finland in 1964-2017 and their mortality in 1972-2017. Survival analyses were used to study long-term trends in survival and abridged period life table methods to calculate life expectancy estimates. Causes of death were examined to consider development. RESULTS: Study data included 42,936 persons with type 1 diabetes and 6,771 deaths. Kaplan-Meier curves showed improved survival during the study period. In 2017, the remaining life expectancy at the age of 20 for a person diagnosed for type 1 diabetes was estimated to be 51.64 (95% CI: 51.51, 51.78) years which was 9.88 (9.74, 10.01) years lower than for the general Finnish population. CONCLUSIONS: We found improved survival among persons with type 1 diabetes during the last decades. However, their life expectancy remained significantly below that of the general Finnish population. Our results call for further innovations and improvements in diabetes care.

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  • Improvements in the average life expectancy of people with type 1 diabetes mellitus have contributed to the growing number of older people living with this disease.

    “Improvements in the average life expectancy of people with T1DM have also contributed to the growing number of older people living with this disease.”

    From The epidemiology of type 1 diabetes mellitus in older adults (2025) · cites this paper as [5]

    The Discussion reports improved survival among people with type 1 diabetes in Finland from 1972 to 2017, and the Results report a marked increase in average age at death. The paper does not establish that the number of older people living with type 1 diabetes has grown or measure how much improved life expectancy contributed to such growth. (LLM, conf=0.84)

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  • In Finland, mortality in 2017 ranged from 25.5 per 1,000 persons with type 1 diabetes mellitus aged 60-64 years to 76.4 per 1,000 persons aged 75-79 years.

    “In Finland, mortality in 2017 ranged from 25.5 per 1,000 persons with T1DM aged 60–64 years to 76.4 per 1,000 persons aged 75–79 years5.”

    From The epidemiology of type 1 diabetes mellitus in older adults (2025) · cites this paper as [5]

    The Results section reports survival and life expectancy for people with type 1 diabetes in Finland, but not the claimed 2017 mortality rates for ages 60–64 and 75–79. Searches for 25.5, 76.4, and those age groups found no matching rates in our copy. No page numbers were available for these passages. (LLM, conf=0.74)

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  1. Green A, Hede SM, Patterson CC, Wild SH, Imperatore G, Roglic GT, et al. Type 1 diabetes in 2017: global estimates of incident and prevalent cases in children and adults. Diabetologia 2017;2021:2741-50. https://doi.org/10.1007/s00125-021- 05571-8. · DOI
  2. Morgan E, Cardwell C, Black CJ, McCance DR, Patterson CC. Excess mortality in Type 1 diabetes diagnosed in childhood and adolescence: a systematic review of population-based cohorts. Acta Diabetol 2015:801-7. https://doi.org/10.1007/ s00592-014-0702-z. · DOI
  3. Lin X, Xu Y, Pan X, Xu J, Ding Y, Sun X, et al. Global, regional, and national burden and trend of diabetes in 195 countries and territories: an analysis from 1990 to 2025. Sci Rep 2020;1:14790-9. https://doi.org/10.1038/s41598-020-71908-9. · DOI
  4. Gomez-Lopera N, Pineda-Trujillo N, Diaz-Valencia PA. Correlating the global increase in type 1 diabetes incidence across age groups with national economic prosperity: A systematic review. World J Diabetes 2019;12:560-80. https://doi. org/10.4239/wjd.v10.i12.560. · DOI
  5. Patterson CC, Harjutsalo V, Rosenbauer J, Neu A, Cinek O, Skrivarhaug T, et al. Trends and cyclical variation in the incidence of childhood type 1 diabetes in 26 European centres in the 25 year period 1989-2013: a multicentre prospective registration study. Diabetologia 2019;3:408-17. https://doi.org/10.1007/s00125- 018-4763-3. · DOI
  6. Parviainen A, But A, Siljander H, Knip M, Finnish Pediatric Diabetes Register. Decreased Incidence of Type 1 Diabetes in Young Finnish Children. Diabetes Care 2020;12:2953-8. https://doi.org/10.2337/dc20-0604. · DOI
  7. Lawrence JM, Divers J, Isom S, Saydah S, Imperatore G, Pihoker C, et al. Trends in Prevalence of Type 1 and Type 2 Diabetes in Children and Adolescents in the US, 2001-2017. JAMA 2021;8:717-27. https://doi.org/10.1001/jama.2021.11165. · DOI
  8. Huo L, Harding JL, Peeters A, Shaw JE, Magliano DJ. Life expectancy of type 1 diabetic patients during 1997-2010: a national Australian registry-based cohort study. Diabetologia 2016;6:1177-85. https://doi.org/10.1007/s00125-015-3857- 4. · DOI · Paper page
  9. Petrie D, Lung TW, Rawshani A, Palmer AJ, Svensson AM, Eliasson B, et al. Recent trends in life expectancy for people with type 1 diabetes in Sweden. Diabetologia 2016;6:1167-76. https://doi.org/10.1007/s00125-016-3914-7. · DOI
  10. Ou HT, Yang CY, Wang JD, Hwang JS, Wu JS. Life Expectancy and Lifetime Health Care Expenditures for Type 1 Diabetes: A Nationwide Longitudinal Cohort of Incident Cases Followed for 14 Years. Value Health 2016;8:976-84. https://doi. org/10.1016/j.jval.2016.05.017. · DOI
  11. Miller RG, Secrest AM, Sharma RK, Songer TJ, Orchard TJ. Improvements in the Life Expectancy of Type 1 Diabetes. Diab J Am Diab Assoc 2012;11:2987-92. https://doi.org/10.2337/db11-1625. · DOI · Paper page
  12. Gagnum V, Stene LC, Sandvik L, Fagerland MW, Njølstad PR, Joner G, et al. All- cause mortality in a nationwide cohort of childhood-onset diabetes in Norway 1973-2013. Diabetologia 2015;8:1779-86. https://doi.org/10.1007/s00125-015- 3623-7. · DOI
  13. Podar T, Solntsev A, Reunanen A, Urbonaite B, Zalinkevicius R, Karvonen M, et al. Mortality in patients with childhood-onset type 1 diabetes in Finland, Estonia, and Lithuania: follow-up of nationwide cohorts. Diabetes Care 2000;3:290-4. https:// doi.org/10.2337/diacare.23.3.290. · DOI
  14. Forssas E, Sund R, Manderbacka K, Arffman M, Ilanne-Parikka P, Keskimaki I. Increased cancer mortality in diabetic people treated with insulin: a register-based follow-up study. BMC Health Serv Res 2013::267. https://doi.org/10.1186/1472- 6963-13-267. · DOI
  15. Harjutsalo V, Barlovic DP, Gordin D, Forsblom C, King G, Groop P. Presence and Determinants of Cardiovascular Disease and Mortality in Individuals With Type 1 Diabetes of Long Duration: The FinnDiane 50 Years of Diabetes Study. Diabetes Care 2021;8:1885-93. https://doi.org/10.2337/dc20-2816. · DOI
  16. Galloway JA. Insulin Treatment for the Early 80s: Facts and Questions About Old and New Insulins and Their Usage. Diabetes Care 1980;5:615-22. https://doi.org/ 10.2337/diacare.3.5.615. · DOI
  17. Kesavadev J, Saboo B, Krishna MB, Krishnan G. Evolution of Insulin Delivery Devices: From Syringes, Pens, and Pumps to DIY Artificial Pancreas. Diabetes Ther 2020;6:1251-69. https://doi.org/10.1007/s13300-020-00831-z. · DOI · Paper page
  18. Nathan DM, Genuth S, Lachin J, Cleary P, Crofford O, Davis M, et al. The Effect of Intensive Treatment of Diabetes on the Development and Progression of Long-Term Complications in Insulin-Dependent Diabetes Mellitus. N Engl J Med 1993;14: 977-86. https://doi.org/10.1056/NEJM199309303291401. · DOI · Paper page
  19. Zimmerman C, Albanese-O'Neill A, Haller MJ. Advances in Type 1 Diabetes Technology Over the Last Decade. Eur Endocrinol 2019;2:70-6. https://doi.org/ 10.17925/EE.2019.15.2.70. · DOI
  20. Harjutsalo V, Forsblom C, Groop P. Time trends in mortality in patients with type 1 diabetes: nationwide population based cohort study. BMJ 2011;343:d5364. https://doi.org/10.1136/bmj.d5364. · DOI

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Authors
Arffman, M., Hakkarainen, P., Keskimäki, I., Oksanen, T., & Sund, R.
Affiliations
  • Finnish Institute for Health and Welfare (FI)
  • University of Eastern Finland (FI)
Corresponding author
Arffman, Martti
Venue
Diabetes Research and Clinical Practice
Publisher
Elsevier BV
Published
2023-04
Volume
198
Pages
110580
ISSN
0168-8227 (ISSN-L)
OpenAlex
W4321350548
Cited by
58
References
4
Citations by year
2026: 17 · 2025: 24 · 2024: 14 · 2023: 3
FWCI
12.13
Type
journal article
Language
en
Open access
Locations
  • Diabetes Research and Clinical Practice (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • Tampere University Institutional Repository (Tampere University) (submittedVersion, cc-by)
  • STM:n Hallinnonalan avoin julkaisuarkisto (Julkari) (submittedVersion)
Funders
  • Strategic Research Council (336328)
  • Academy of Finland
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Diabetes and associated disorders
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
Keywords
type 1 diabetes, life expectancy, survival trends, mortality, remaining life expectancy, causes of death, diabetes management, Finland
MeSH terms
Diabetes Mellitus, Type 1, Finland, Humans, Life Expectancy, Survival Analysis

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