Cited by 463SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesCOVID-19 epidemiological studies

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Clinical, molecular, and epidemiological characterization of the SARS-CoV-2 virus and the Coronavirus Disease 2019 (COVID-19), a comprehensive literature review

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Ortiz-Prado, Esteban, Simbaña-Rivera, Katherine, Gómez- Barreno, Lenin, Rubio-Neira, Mario, Guaman, Linda P., Kyriakidis, Nikolaos C, Muslin, Claire, Jaramillo, Ana María Gómez, Barba-Ostria, Carlos, Cevallos-Robalino, Doménica, Sanches-SanMiguel, Hugo, Unigarro, Luis, Zalakeviciute, Rasa, Gadian, Naomi, López-Cortés, Andrés·2020·Diagnostic Microbiology and Infectious Disease

DOI 10.1016/j.diagmicrobio.2020.115094PMC PMC7260568

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Abstract

Coronaviruses are an extensive family of viruses that can cause disease in both animals and humans. The current classification of coronaviruses recognizes 39 species in 27 subgenera that belong to the family Coronaviridae. From those, at least 7 coronaviruses are known to cause respiratory infections in humans. Four of these viruses can cause common cold-like symptoms. Those that infect animals can evolve and become infectious to humans. Three recent examples of these viral jumps include SARS CoV, MERS-CoV and SARS CoV-2 virus. They are responsible for causing severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS) and the most recently discovered coronavirus disease during 2019 (COVID-19). COVID-19, a respiratory disease caused by the SARS-CoV-2 virus, was declared a pandemic by the World Health Organization (WHO) on 11 March 2020. The rapid spread of the disease has taken the scientific and medical community by surprise. Latest figures from 20 May 2020 show more than 5 million people had been infected with the virus, causing more than 330,000 deaths in over 210 countries worldwide. The large amount of information received daily relating to COVID-19 is so abundant and dynamic that medical staff, health authorities, academics and the media are not able to keep up with this new pandemic. In order to offer a clear insight of the extensive literature available, we have conducted a comprehensive literature review of the SARS CoV-2 Virus and the Coronavirus Diseases 2019 (COVID-19).

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Authors: Ortiz-Prado, E., Simbaña-Rivera, K., Gómez- Barreno, L., Rubio-Neira, M., Guaman, L. P., Kyriakidis, N. C., Muslin, C., Jaramillo, A. M. G., Barba-Ostria, C., Cevallos-Robalino, D., Sanches-SanMiguel, H., Unigarro, L., Zalakeviciute, R., Gadian, N., & López-Cortés, A.
Affiliations: Pediatric Hospital "Baca Ortiz" (EC)
Universidad de Las Américas (EC)
Hospital General del Sur de Quito, IESS (EC)
SOLCA Núcleo de Quito (EC)
University of Southampton (GB)
ORCID: Kyriakidis, Nikolaos C
Muslin, Claire
Cevallos-Robalino, Doménica
Unigarro, Luis
Venue: Diagnostic Microbiology and Infectious Disease
Publisher: Elsevier BV
Published: 2020-09
Volume: 98
Issue: 1
Pages: 115094
ISSN: 0732-8893 (ISSN-L)
DOI: 10.1016/j.diagmicrobio.2020.115094
PMC: PMC7260568
OpenAlex: W3017016822
Cited by: 458
References: 275
Citations by year: 2026: 7 · 2025: 19 · 2024: 36 · 2023: 72 · 2022: 108 · 2021: 151 · 2020: 65
FWCI: 4.68
Type: journal article
Language: en
Open access: green
doi.org
Licence: cc-by
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Diagnostic Microbiology and Infectious Disease (publishedVersion)
Preprints.org (acceptedVersion, cc-by)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
Physical Sciences › Mathematics › Modeling and Simulation › COVID-19 epidemiological studies
Keywords: SARS-CoV-2, COVID-19 pandemic, coronavirus, Coronaviridae, SARS, MERS, zoonotic transmission, respiratory infections, pandemic, clinical characterization, molecular characterization
MeSH terms: Betacoronavirus, COVID-19, SARS-CoV-2, Humans, Pneumonia, Viral, Virus Replication, HIV Infections, Genome, Viral, Coronavirus Infections, Pandemics

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Clinical, molecular, and epidemiological characterization of the SARS-CoV-2 virus and the Coronavirus Disease 2019 (COVID-19), a comprehensive literature review

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