DNA replication as a target of the DNA damage checkpoint

Ordered assembly of Sld3, GINS and Cdc45 is distinctly regulated by DDK and CDK for activation of replication origins

Yabuuchi, H., Yamada, Y., Uchida, T., Sunathvanichkul, T., Nakagawa, T., & Masukata, H. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7601347 · Cited by 100

Activation of Silent Replication Origins at Autonomously Replicating Sequence Elements near the HML Locus in Budding Yeast

Vujcic, M., Miller, C. A., & Kowalski, D. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.9.6098 · Cited by 99

Cell cycle progression in the presence of irreparable DNA damage is controlled by a Mec1‐ and Rad53‐dependent checkpoint in budding yeast

Neecke, H., Lucchini, G., & Pia Longhese, M. (1999) · The EMBO Journal · doi:10.1093/emboj/18.16.4485 · Cited by 94

GENOME-WIDE RESPONSES TO DNA-DAMAGING AGENTS

Fry, R. C., Begley, T. J., & Samson, L. D. (2005) · Annual Review of Microbiology · doi:10.1146/annurev.micro.59.031805.133658 · Cited by 94

Cell Cycle Regulation of DNA Replication Initiator Factor Dbf4p

Cheng, L., Collyer, T., & Hardy, C. F. J. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.6.4270 · Cited by 92

The Cdc23 (Mcm10) protein is required for the phosphorylation of minichromosome maintenance complex by the Dfp1-Hsk1 kinase

Lee, J.-K., Seo, Y., & Hurwitz, J. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0237384100 · Cited by 90

Cell cycle regulation of Dfp1, an activator of the Hsk1 protein kinase

Brown, G. W., & Kelly, T. J. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.15.8443 · Cited by 87

The Cdc7/Dbf4 protein kinase: target of the S phase checkpoint?

Jares, P., Donaldson, A. D., & Blow, J. J. (2000) · EMBO Reports · doi:10.1093/embo-reports/kvd076 · Cited by 86

Esc4p, a new target of Mec1p (ATR), promotes resumption of DNA synthesis after DNA damage

Rouse, J. W. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600129 · Cited by 86

Replication foci dynamics: replication patterns are modulated by S‐phase checkpoint kinases in fission yeast

Meister, P., Taddei, A., Ponti, A., Baldacci, G., & Gasser, S. M. (2007) · The EMBO Journal · doi:10.1038/sj.emboj.7601538 · Cited by 86

Assembly of a Double Hexameric Helicase

Schuck, S., & Stenlund, A. (2005) · Molecular Cell · doi:10.1016/j.molcel.2005.09.020 · Cited by 84

Temporal separation of replication and recombination requires the intra-S checkpoint

Meister, P., Taddei, A., Vernis, L., Poidevin, M., Gasser, S. M., & Baldacci, G. (2005) · The Journal of Cell Biology · doi:10.1083/jcb.200410006 · Cited by 84

Unwind and slow down: checkpoint activation by helicase and polymerase uncoupling: Figure 1.

Cortez, D. (2005) · Genes & Development · doi:10.1101/gad.1316905 · Cited by 84

Characterization of a novel ATR-dependent, Chk1-independent, intra-S-phase checkpoint that suppresses initiation of replication inXenopus

Luciani, M. G., Oehlmann, M., & Blow, J. J. (2004) · Journal of Cell Science · doi:10.1242/jcs.01400 · Cited by 83

DNA replication is required for the checkpoint response to damaged DNA in Xenopus egg extracts

Stokes, M. P., Hatten, R. A. V., Lindsay, H. D., & Michael, W. M. (2002) · The Journal of Cell Biology · doi:10.1083/jcb.200204127 · Cited by 82

Schizosaccharomyces pombe Hsk1p Is a Potential Cds1p Target Required for Genome Integrity

Snaith, H. A., Brown, G. W., & Forsburg, S. L. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.21.7922-7932.2000 · Cited by 79

The role of CDK in the initiation step of DNA replication in eukaryotes

Tanaka, S., Tak, Y., & Araki, H. (2007) · Cell Division · doi:10.1186/1747-1028-2-16 · Cited by 77

Characterization of the Yeast Cdc7p/Dbf4p Complex Purified from Insect Cells

Kihara, M., Nakai, W., Asano, S., Suzuki, A., Kitada, K., Kawasaki, Y., Johnston, L. H., & Sugino, A. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m003491200 · Cited by 75

Control of ribonucleotide reductase localization through an anchoring mechanism involving Wtm1Preprint

Lee, Y. D., & Elledge, S. J. (2006) · Genes & Development · doi:10.1101/gad.1380506 · Cited by 74

DNA replication checkpoint promotes G 1 -S transcription by inactivating the MBF repressor Nrm1

de Bruin, R. A. M., Kalashnikova, T. I., Aslanian, A., Wohlschlegel, J. A., Chahwan, C., Yates, J. R., Russell, P. R., & Wittenberg, C. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0801106105 · Cited by 74

Cdt1 degradation to prevent DNA re-replication: conserved and non-conserved pathways

Kim, Y., & Kipreos, E. T. (2007) · Cell Division · doi:10.1186/1747-1028-2-18 · Cited by 74

Replication origin plasticity, Taylor-made: inhibition vs recruitment of origins under conditions of replication stress

Gilbert, D. M. (2007) · Chromosoma · doi:10.1007/s00412-007-0105-9 · Cited by 72

SpSld3 Is Required for Loading and Maintenance of SpCdc45 on Chromatin in DNA Replication in Fission Yeast

Nakajima, R., & Masukata, H. (2002) · Molecular Biology of the Cell · doi:10.1091/mbc.02-01-0006 · Cited by 68

Replication origins in the eucaryotic chromosome

Laskey, R. A., & Harland, R. M. (1981) · Cell · doi:10.1016/0092-8674(81)90316-0 · Cited by 66

The Schizosaccharomyces pombe Replication Inhibitor Spd1 Regulates Ribonucleotide Reductase Activity and dNTPs by Binding to the Large Cdc22 Subunit

Håkansson, P., Dahl, L., Chilkova, O., Domkin, V., & Thelander, L. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m511716200 · Cited by 65

A mutation in EXO1 defines separable roles in DNA mismatch repair and post-replication repair

Tran, P. T., Fey, J. P., Erdeniz, N., Gellon, L., Boiteux, S., & Liskay, R. M. (2007) · DNA repair · doi:10.1016/j.dnarep.2007.05.004 · Cited by 60

The comparative effects of short-term DNA inhibition on replicon synthesis in mammalian cells

Ockey, C. H., & Saffhill, R. (1976) · Experimental Cell Research · doi:10.1016/0014-4827(76)90272-x · Cited by 57

The DNA Replication Checkpoint Directly Regulates MBF-Dependent G1/S Transcription

Dutta, C., Patel, P. K., Rosebrock, A. P., Oliva, A., Leatherwood, J., & Rhind, N. (2008) · Molecular and Cellular Biology · doi:10.1128/mcb.00596-08 · Cited by 53

RAD53 Regulates DBF4 Independently of Checkpoint Function in Saccharomyces cerevisiae

Dohrmann, P. R., Oshiro, G., Tecklenburg, M., & Sclafani, R. A. (1999) · Genetics · doi:10.1093/genetics/151.3.965 · Cited by 50

The DNA Damage Checkpoint in Embryonic Cell Cycles Is Dependent on the DNA-to-Cytoplasmic Ratio

Conn, C. W., Lewellyn, A. L., & Maller, J. L. (2004) · Developmental Cell · doi:10.1016/j.devcel.2004.07.003 · Cited by 49

DNA replication timing is deterministic at the level of chromosomal domains but stochastic at the level of replicons in Xenopus egg extracts

Labit, H., Perewoska, I., Germe, T. R., Hyrien, O., & Marheineke, K. (2008) · Nucleic Acids Research · doi:10.1093/nar/gkn533 · Cited by 49

Chromosome replication in early development of Xenopus laevis

Laskey, R. A. (1985) · Development · doi:10.1242/dev.89.supplement.285 · Cited by 44

In Xenopus Egg Extracts, DNA Replication Initiates Preferentially at or near Asymmetric AT Sequences

Stanojčić, S., Lemaı̂tre, J.-M., Brodolin, K. L., Danis, E. P., & Méchali, M. (2008) · Molecular and Cellular Biology · doi:10.1128/mcb.00181-08 · Cited by 39

Metazoan Origin Selection

Harvey, K. J., & Newport, J. W. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m307661200 · Cited by 39

DNA Replication Forks Pause at Silent Origins near the HML Locus in Budding Yeast

Wang, Y., Vujcic, M., & Kowalski, D. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.15.4938-4948.2001 · Cited by 39

Fission Yeast Mcm10p Contains Primase Activity

Fien, K., & Hurwitz, J. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m512997200 · Cited by 35

Phosphorylation of replication protein A by S-phase checkpoint kinases

Liu, J., Kuo, S., & Melendy, T. (2006) · DNA repair · doi:10.1016/j.dnarep.2005.11.007 · Cited by 27

On the Slowing of S Phase in Response to DNA Damage in Fission Yeast

Kumar, S., & Huberman, J. A. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m407819200 · Cited by 25

G1/S CDK is inhibited to restrain mitotic onset when DNA replication is blocked in fission yeast

Zarzov, P., Decottignies, A., Baldacci, G., & Nurse, P. (2002) · The EMBO Journal · doi:10.1093/emboj/cdf346 · Cited by 25

Essential role of Chk1 in S phase progression through regulation of RNR2 expression

Naruyama, H., Shimada, M., Niida, H., Zineldeen, D. H., Hashimoto, Y., Kohri, K., & Nakanishi, M. (2008) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2008.06.112 · Cited by 23

Control of cell cycle transcription during G1 and S phases

Bertoli, C., Skotheim, J. M., & de Bruin, R. A. M. (2013) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3629 · Cited by 1,567

Co-occurring genomic alterations in non-small-cell lung cancer biology and therapy

Skoulidis, F., & Heymach, J. V. (2019) · Nature Reviews Cancer · doi:10.1038/s41568-019-0179-8 · Cited by 1,019

Maintaining genome stability at the replication fork

Branzei, D., & Foiani, M. (2010) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2852 · Cited by 786

Eukaryotic DNA replication origins: many choices for appropriate answers

Méchali, M. (2010) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2976 · Cited by 441

An overview of Cdk1-controlled targets and processes

Enserink, J. M., & Kolodner, R. D. (2010) · Cell Division · doi:10.1186/1747-1028-5-11 · Cited by 409

Checkpoint and Coordinated Cellular Responses to DNA Damage

Yang, X. H., & Zou, L. (2006) · Springer eBooks · doi:10.1007/b136684 · Cited by 20

The checkpoint response to replication stress

Branzei, D., & Foiani, M. (2009) · DNA repair · doi:10.1016/j.dnarep.2009.04.014 · Cited by 214

DNA replication checkpoint

Boddy, M. N., & Russell, P. R. (2001) · Current Biology · doi:10.1016/s0960-9822(01)00572-3 · Cited by 121

Replication Checkpoint: Tuning and Coordination of Replication Forks in S Phase

Hustedt, N., Gasser, S. M., & Shimada, K. (2013) · Genes · doi:10.3390/genes4030388 · Cited by 62

A DNA replication fork-centric view of the budding yeast DNA damage response

McClure, A. W., Canal, B., & Diffley, J. F. X. (2022) · DNA repair · doi:10.1016/j.dnarep.2022.103393 · Cited by 24