DNA double-strand break repair pathway choice and cancer

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Items 101–200 of 346

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3. Functional Polymorphisms in DNA Repair Genes Are Associated with Sporadic Colorectal Cancer Susceptibility and Clinical Outcome
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4. Elucidation of the Clustered Nano-Architecture of Radiation-Induced DNA Damage Sites and Surrounding Chromatin in Cancer Cells: A Single Molecule Localization Microscopy Approach
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6. Nuclear poly(A)-binding protein 1 is an ATM target and essential for DNA double-strand break repair
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7. RB Regulates DNA Double Strand Break Repair Pathway Choice by Mediating CtIP Dependent End Resection
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8. Analysis of chromatid-break-repair detects a homologous recombination to non-homologous end-joining switch with increasing load of DNA double-strand breaks
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12. Spontaneous γH2AX foci in human dermal fibroblasts in relation to proliferation activity and aging
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13. Topological Analysis of γH2AX and MRE11 Clusters Detected by Localization Microscopy during X-ray-Induced DNA Double-Strand Break Repair
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15. DNA Double Strand Break and Response Fluorescent Assays: Choices and Interpretation
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21. Measurement of DNA damage in peripheral blood by the γ-H2AX assay as predictor of colorectal cancer risk
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23. A SWI/SNF subunit regulates chromosomal dissociation of structural maintenance complex 5 during DNA repair in plant cells
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24. Chronic arsenic exposure suppresses ATM pathway activation in human keratinocytes
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26. SNM1B/Apollo in the DNA damage response and telomere maintenance
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27. DNA Double Strand Breaks Repair Inhibitors: Relevance as Potential New Anticancer Therapeutics
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28. Mechanism of Action Studies of Lomaiviticin A and the Monomeric Lomaiviticin Aglycon. Selective and Potent Activity Toward DNA Double-Strand Break Repair-Deficient Cell Lines
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29. PC4-mediated Ku complex PARylation facilitates NHEJ-dependent DNA damage repair
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30. Local sequence assembly reveals a high-resolution profile of somatic structural variations in 97 cancer genomes
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32. Beyond interstrand crosslinks repair: contribution of FANCD2 and other Fanconi Anemia proteins to the replication of DNA
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33. Identification and Validation of ERK5 as a DNA Damage Modulating Drug Target in Glioblastoma
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34. Advances of DNA Damage Repair-Related Drugs and Combination With Immunotherapy in Tumor Treatment
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35. Role for RIF1-interacting partner DDX1 in BLM recruitment to DNA double-strand breaks
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36. PD-L1 deficiency sensitizes tumor cells to DNA-PK inhibition and enhances cGAS-STING activation.
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37. FANCJ helicase controls the balance between short- and long-tract gene conversions between sister chromatids
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38. Targeting Base Excision Repair in Cancer: NQO1-Bioactivatable Drugs Improve Tumor Selectivity and Reduce Treatment Toxicity Through Radiosensitization of Human Cancer
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39. Overview of DNA repair pathways, current targets, and clinical trials bench to clinic
    Mark R. Kelley, Melissa L. Fishel · 2016 · Elsevier eBooks
40. DNA Double Strand Break Repair - Related Synthetic Lethality
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41. Quantitative Insights into Age-Associated DNA-Repair Inefficiency in Single Cells
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42. Multicellular Complex Tumor Spheroid Response to DNA Repair Inhibitors in Combination with DNA-damaging Drugs
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43. Small Molecule Inhibitors Targeting Key Proteins in the DNA Damage Response for Cancer Therapy
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44. Single Molecule Localization Microscopy Analyses of DNA-Repair Foci and Clusters Detected Along Particle Damage Tracks
    Michael Hausmann, Charlotte Neitzel, Elizaveta Bobkova, David Nagel, Andreas Hofmann, Tatyana Chramko, Elena Smirnova, Olga Kopečná, Eva Pagáčová, Alla V. Boreyko et al. · 2020 · Frontiers in Physics
45. Systematic evaluation of underlying defects in DNA repair as an approach to case-only assessment of familial prostate cancer
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46. Recent insights into the causes and consequences of chromosome mis-segregation
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47. A Role for RAGE in DNA Double Strand Breaks (DSBs) Detected in Pathological Placentas and Trophoblast Cells
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48. Mechanistic Insights From Single-Molecule Studies of Repair of Double Strand Breaks
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49. Cooperative dynamics of PARP-1 zinc-finger domains in the detection of DNA single-strand breaks
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50. Bioassay-directed analysis-based identification of relevant pyrrolizidine alkaloids
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51. Neuronal Nitric Oxide Synthase-Mediated Genotoxicity of 2-Methoxyestradiol in Hippocampal HT22 Cell Line
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52. Genetic variants in microRNA‐binding sites of DNA repair genes as predictors of recurrence in patients with squamous cell carcinoma of the oropharynx
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53. Essential Roles for Polymerase Theta-Mediated End Joining in Repair of Chromosome Breaks
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54. The conserved Tpk1 regulates non-homologous end joining double-strand break repair by phosphorylation of Nej1, a homolog of the human XLF
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56. Co-targeting c-Met and DNA double-strand breaks (DSBs): Therapeutic strategies in BRCA-mutated gastric carcinomas
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57. Multi-omics data integration analysis identifies the spliceosome as a key regulator of DNA double-strand break repair
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74. BRCA1-CtIP interaction in the repair of DNA double-strand breaks
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