DNA double-strand break repair pathway choice and cancer

A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

Jinek, M., Chylinski, K., Fonfara, I., Hauer, M., Doudna, J. A., & Charpentier, E. (2012) · Science · doi:10.1126/science.1225829 · Cited by 17,116

The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway

Lieber, M. R. (2010) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.052308.093131 · Cited by 2,882

Massive genomic rearrangement acquired in a single catastrophic event during cancer development

Stephens, P. J., Greenman, C. D., Fu, B., Yang, F., Bignell, G. R., Mudie, L. J., Pleasance, E. D., Lau, K. W., Beare, D., Stebbings, L. A., et al. (2011) · Cell · doi:10.1016/j.cell.2010.11.055 · Cited by 2,414

DNA damage, aging, and Cancer

Hoeijmakers, J. H. J. (2009) · New England Journal of Medicine · doi:10.1056/nejmra0804615 · Cited by 2,239

A TALE nuclease architecture for efficient genome editing

Miller, J. C., Tan, S., Qiao, G., Barlow, K. A., Wang, J., Xia, D. F., Meng, X., Paschon, D. E., Leung, E., Hinkley, S. J., et al. (2011) · Nature Biotechnology · doi:10.1038/nbt.1755 · Cited by 2,098

53BP1 Inhibits Homologous Recombination in Brca1-Deficient Cells by Blocking Resection of DNA Breaks

Bunting, S. F., Callén, E., Wong, N., Chen, H.-T., Polato, F., Gunn, A., Bothmer, A., Feldhahn, N., Fernandez-Capetillo, O., Cao, L., et al. (2010) · Cell · doi:10.1016/j.cell.2010.03.012 · Cited by 1,671

Highly efficient endogenous human gene correction using designed zinc-finger nucleases

Urnov, F. D., Miller, J. C., Lee, Y.-L., Beausejour, C. M., Rock, J. M., Augustus, S., Jamieson, A. C., Porteus, M. H., Gregory, P. D., & Holmes, M. C. (2005) · Nature · doi:10.1038/nature03556 · Cited by 1,642

Double-Strand Break End Resection and Repair Pathway Choice

Symington, L. S., & Gautier, J. (2011) · Annual Review of Genetics · doi:10.1146/annurev-genet-110410-132435 · Cited by 1,556

Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination

Ma, Y., Pannicke, U., Schwarz, K., & Lieber, M. R. (2002) · Cell · doi:10.1016/s0092-8674(02)00671-2 · Cited by 1,166

DNA interstrand crosslink repair and cancer

Deans, A. J., & West, S. C. (2011) · Nature reviews. Cancer · doi:10.1038/nrc3088 · Cited by 1,063

Drosophila Xrcc2 regulates DNA double-strand repair in somatic cells

Bayer, F. E., Deichsel, S., Mahl, P., & Nagel, A. C. (2020) · DNA repair · doi:10.1016/j.dnarep.2020.102807 · Cited by 7

Inflammation accelerates BCR-ABL1+ B-ALL development through upregulation of AID

Zhang, P., Qin, M., Wang, Y., Chen, X., Miao, Y., Yuan, M., Zhou, W., Li, D., Wang, D., Wang, M., et al. (2022) · Blood Advances · doi:10.1182/bloodadvances.2021005017 · Cited by 7

Association between miRNA-binding site polymorphisms in double-strand break repair genes and risk of recurrence in patients with squamous cell carcinomas of the non-oropharynx

Zhu, L., Sturgis, E. M., Lu, Z., Zhang, H., Wei, P., Wei, Q., & Li, G. (2017) · Carcinogenesis · doi:10.1093/carcin/bgx019 · Cited by 7

Potential Roles of the Retinoblastoma Protein in Regulating Genome Editing

Jiang, Y., & Chu, W. K. (2018) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2018.00081 · Cited by 7

Purification and Biophysical Characterization of the Mre11-Rad50-Nbs1 Complex

Myler, L. R., Soniat, M. M., Zhang, X., Deshpande, R. A., Paull, T. T., & Finkelstein, I. J. (2019) · Methods in molecular biology · doi:10.1007/978-1-4939-9520-2_20 · Cited by 7

Age-related activity of Poly (ADP-Ribose) Polymerase (PARP) in men with localized prostate cancer

Deniz, M., Zengerling, F., Gundelach, T., Moreno‐Villanueva, M., Bürkle, A., Janni, W., Bolenz, C., Kostezka, S., Marienfeld, R. B., Benckendorff, J., et al. (2021) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2021.111494 · Cited by 7

High-Throughput Analysis of DNA Break-Induced Chromosome Rearrangements by Amplicon Sequencing

Brown, A. J., Al-Soodani, A. T., Saul, M., Her, S. C., Carvajal-Garcia, J., Ramsden, D. A., Her, C., & Roberts, S. A. (2018) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/bs.mie.2017.11.028 · Cited by 7

DNA damage and repair in cardiomyopathy: mechanisms and therapeutic opportunities

Zhou, X., Yu, Z., Chen, Z., Evans, S. Μ., & Chen, J. (2025) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00774.2025 · Cited by 6

PARP1 trapping activates cGAS-STING pathway to induce immunogenic cell death in multiple myeloma

Juli, G., Ronchetti, D., Signorelli, S., Squillacioti, S., Polerà, N., Maienza, A., Vocaturo, M., Galvano, A., Taìana, E., Tagliaferri, P., et al. (2026) · Cancer Cell International · doi:10.1186/s12935-025-04152-8 · Cited by 6

Incorporation of 53BP1 into phase-separated bodies in cancer cells during aberrant mitosis

Bleiler, M., Cyr, A., Wright, D. L., & Giardina, C. A. (2023) · Journal of Cell Science · doi:10.1242/jcs.260027 · Cited by 6

Identification and Validation of New DNA-PKcs Inhibitors through High-Throughput Virtual Screening and Experimental Verification

Dai, L., Yu, P., Fan, H., Xia, W., Zhao, Y., Zhang, P., Zhang, J. Z. H., Zhang, H., & Chen, Y. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25147982 · Cited by 6

Metastasis Suppressor NME1 Modulates Choice of Double-Strand Break Repair Pathways in Melanoma Cells by Enhancing Alternative NHEJ while Inhibiting NHEJ and HR

Puts, G. S., Jarrett, S. G., Leonard, M. K., Matsangos, N., Snyder, D. E., Wang, Y., Vincent, R., Portney, B. A., Abbotts, R., McLaughlin, L. J., et al. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21165896 · Cited by 6

Bioinformatics prediction of differential miRNAs in non-small cell lung cancer

Xiao, K., Liu, S., Xiao, Y., Wang, Y., Zhu, Z., Wang, Y., Tong, D., & Jiang, J. (2021) · PLoS ONE · doi:10.1371/journal.pone.0254854 · Cited by 6

Dynamic Genomes - Mechanisms and consequences of genomic diversity impacting plant-fungal interactions

Huang, J. T., Liu, S., & Cook, D. E. (2023) · Physiological and Molecular Plant Pathology · doi:10.1016/j.pmpp.2023.102006 · Cited by 6

Association of expression quantitative trait loci for long noncoding RNAs with lung cancer risk in Asians

Sun, Q., Wang, Y., Fan, J., Li, Z., Zhang, J., Wang, L., Fan, X., Ji, M., Zhu, M., Dai, J., et al. (2019) · Molecular Carcinogenesis · doi:10.1002/mc.23013 · Cited by 6

Treacle is Upregulated in Cancer and Correlates With Poor Prognosis

Oxe, K. C., & Larsen, D. H. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.918544 · Cited by 6

Retinoblastoma family proteins: New players in DNA repair by non-homologous end-joining

Huang, P. H., Cook, R., Zoumpoulidou, G., Luczynski, M. T., & Mittnacht, S. (2015) · Molecular & Cellular Oncology · doi:10.1080/23723556.2015.1053596 · Cited by 6

Abscopal Effect with Liver-Directed Therapy: A Review of the Current Literature and Future Directions

Levine, J. M., Habib, A., Silk, M. T., Sacks, G. D., Winograd, R., Hill, C., Javed, A. A., Wolfgang, C. L., & Hewitt, D. B. (2024) · Livers · doi:10.3390/livers4040042 · Cited by 5

ATM kinase inhibitor KU-55933 contribution in cisplatin mediated HeLa proliferation

Bhatkar, D., Kumar, A., Jahagirdar, D., Purohit, S., & Sharma, N. K. (2016) · International Journal of Pharmacology and Toxicology · doi:10.14419/ijpt.v4i2.6644 · Cited by 5

Genomic Instability and DNA Repair in Cancer

Das, B., Choudhury, B., Kumar, A. A., & Baruah, V. J. (2021) · IntechOpen eBooks · doi:10.5772/intechopen.95736 · Cited by 5

The activation mechanisms of master kinases in the DNA damage response

Xiao, J., Rao, Q., & Xu, Y. (2021) · Genome Instability & Disease · doi:10.1007/s42764-021-00045-y · Cited by 5

A Stochastic Model of DNA Double-Strand Breaks Repair Throughout the Cell Cycle

Mohseni-Salehi, F. S., Zare‐Mirakabad, F., Sadeghi, M., & Ghafouri‐Fard, S. (2020) · Bulletin of Mathematical Biology · doi:10.1007/s11538-019-00692-z · Cited by 6

The 5-WS of targeting DNA-damage repair (DDR) pathways in prostate cancer

Guida, A., Mosillo, C., Mammone, G., Caserta, C., Sirgiovanni, G., Conteduca, V., & Sergio Bracarda, A. (2024) · Cancer Treatment Reviews · doi:10.1016/j.ctrv.2024.102766 · Cited by 4

Role of Ionizing Radiation in Shaping the Complex Multi-Layered Epigenome

Rübe, C. E., Al‐razaq, M. A. A., Meier, C., Hecht, M., & Rübe, C. (2025) · Epigenomes · doi:10.3390/epigenomes9030029 · Cited by 5

DNA Damage and Repair in Pancreatic Cancer—The Latest Findings

Kozłowska, M., Mik, M., Nowicki, M. O., & Śliwińska, A. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms262010106 · Cited by 5

GDBr: genomic signature interpretation tool for DNA double-strand break repair mechanisms

Ryu, H. C., Han, H. H., Kim, C., & Kim, J. (2025) · Nucleic Acids Research · doi:10.1093/nar/gkae1295 · Cited by 4

The Role of Glutamine Synthetase on the Sensitivity to Radiotherapy of Hepatocellular Carcinoma

He, Y. M., Yu, H., Lu, Y., Zhou, C., Tian, Y., Song, T., Wang, D., Fang, Z., Zhang, Z., Wang, H., et al. (2025) · Radiation Research · doi:10.1667/rade-22-00181.1 · Cited by 4

Clostridium difficile as a potent trigger of colorectal carcinogenesis

Nezhadi, J., Lahouty, M., Rezaee, M. A., & Fadaee, M. (2025) · Discover Oncology · doi:10.1007/s12672-025-02742-6 · Cited by 4

Effect of ATM –111 (G>A) Polymorphism on Cancer Risk: A Meta-Analysis

Huang, S., Zhang, Y., & Zeng, T. (2016) · Genetic Testing and Molecular Biomarkers · doi:10.1089/gtmb.2015.0320 · Cited by 4

Polymorphisms in PARP1 predict disease-free survival of triple-negative breast cancer patients treated with anthracycline/taxane based adjuvant chemotherapy

Liao, Y., Liao, Y., Li, J., Xiong, J., & Fan, Y. (2020) · Scientific Reports · doi:10.1038/s41598-020-64473-8 · Cited by 4

A Bioluminescence Resonance Energy Transfer–Based Reporter System: Characterization and Applications

Wimmer, T., Bonthu, D., Moeschl, V., Klekamp, P., Thiel, C., Lytvynchuk, L. M., Ellinwood, N. M., & Stieger, K. (2021) · The CRISPR Journal · doi:10.1089/crispr.2021.0023 · Cited by 4

A Simulated Shift Work Schedule Does Not Increase DNA Double-Strand Break Repair by NHEJ in the Drosophila Rr3 System

Bergerson, L., Fitzmaurice, C., Knudtson, T., McCormick, H., & Yu, A. (2022) · Genes · doi:10.3390/genes13010150 · Cited by 4

Direct ionizing radiation and bystander effect in mouse mesenchymal stem cells

Nogueira‐Pedro, A., Segreto, H. R. C., Held, K. D., Ferreira, A. F. G., Dias, C. C., Hastreiter, A. A., Makiyama, E. N., Paredes‐Gamero, E. J., Borelli, P., & Fock, R. A. (2022) · International Journal of Radiation Biology · doi:10.1080/09553002.2022.2063960 · Cited by 4

The molecular details of a novel phosphorylation‐dependent interaction between MRN and the SOSS complex

El‐Kamand, S., Adams, M. N., Matthews, J. M., Plessis, M. D., Crossett, B., Connolly, A. M., Breen, N., Dudley, A., Richard, D. J., Gamsjaeger, R., et al. (2023) · Protein Science · doi:10.1002/pro.4782 · Cited by 4

Identification of ATM-dependent long non-coding RNAs induced in response to DNA damage

Podralska, M., Sajek, M. P., Bielicka, A., Żurawek, M., Ziółkowska‐Suchanek, I., Iżykowska, K., Kolenda, T., Kazimierska, M., Kasprzyk, M. E., Sura, W., et al. (2024) · DNA repair · doi:10.1016/j.dnarep.2024.103648 · Cited by 4

Screening of Long Noncoding RNAs Induced by Radiation Using Microarray

Wang, Y., Wang, Q., Chen, S., Hu, Y., Yu, C., Liu, R., & Wang, Z. (2020) · Dose-Response · doi:10.1177/1559325820916304 · Cited by 4

Pathway choice for DNA double strand break repair

Xu, D., & HuaYu, Z. H. A. O. (2020) · Scientia Sinica Vitae · doi:10.1360/ssv-2020-0196 · Cited by 4

DNA-dependent protein kinase promotes DNA end processing by MRN and CtIPPreprint

Deshpande, R. A., Myler, L. R., Soniat, M. M., Makharashvili, N., Lee, L., Lees-Miller, S. P., Finkelstein, I. J., & Paull, T. T. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/395731 · Cited by 4

Catalytically inactive Cas9 attenuates DNA end resection: A potential application for region-restricted random mutagenesis

Towa, S., Okada, S., & Ito, T. (2025) · iScience · doi:10.1016/j.isci.2025.112702 · Cited by 3

Continuous nuclear envelope surveillance is required for DNA double strand break repair

Medina‐Suárez, S., & Machín, F. (2025) · Communications Biology · doi:10.1038/s42003-025-08416-x · Cited by 3

Discovery of novel thiosemicarbazone dimers as effective inhibitors of poly(ADP-ribose) polymerase-1 (PARP-1) for use in cancer therapy

Wang, L., Wang, Y., Guo, S., Jiang, B., Guo, C., & Wang, G. (2025) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2025.118312 · Cited by 3

Molecular associations and clinical significance of core NHEJ pathway genes in renal clear cell carcinoma

Singh, J., Arora, M., Kumari, S., Verma, D., Palanichamy, J. K., Qamar, I., Chauhan, S. S., & Chopra, A. (2021) · Gene Reports · doi:10.1016/j.genrep.2021.101167 · Cited by 3

Beyond interacting with Rap1: Dissecting the roles of Rif1

Wei, J., Sun, H., Huang, Z., Yang, L., Wu, J., Zhang, J., Liu, M., Li, M., Luo, J., & Wang, H. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.141560 · Cited by 3

Reduced recruitment of 53BP1 during interstrand crosslink repair is associated with genetically inherited attenuation of mitomycin C sensitivity in a family with Fanconi anemia

Lesport, E., Ferster, A., Biver, A., Roch, B., Vasquez, N., Jabado, N., Vives, F. L., Revy, P., Soulier, J., & de Villartay, J. (2017) · Oncotarget · doi:10.18632/oncotarget.23375 · Cited by 3

CRISPR/Cas9-mediated tryptophan hydroxylase 1 knockout decreases calcium transportation in goat mammary epithelial cells

Zhang, Z., Tian, H., Chen, X., Zhao, H., Du, W., Gao, H., Luo, J., & Zheng, H. (2021) · Biochemical Engineering Journal · doi:10.1016/j.bej.2021.108015 · Cited by 3

How structural variation shapes the cancer epigenome

MacLennan, S., & Marra, M. A. (2025) · Trends in cancer · doi:10.1016/j.trecan.2025.09.001 · Cited by 2

Impeding the NHEJ Pathway for Overcoming Radioresistance in the Context of Precision Radiotherapy of Cancer

Niculae, D. A., Serban, R. M., Niculae, D., & Drăgănescu, D. (2026) · Pharmaceutics · doi:10.3390/pharmaceutics18010131 · Cited by 3

Platinum-based therapeutics as emerging multi-modal radiosensitizers in glioblastoma treatment

Elati, A., Davies, E. W., Mishra, M. V., Winkles, J. A., Woodworth, G. F., & Kim, A. J. (2026) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2026.115811 · Cited by 2

DNA polymerase λ autoinhibition is relieved via Ku interaction during non-homologous end joining

Case, B. C., Scoccia, L., Zhao, Z., & Loparo, J. J. (2026) · Nucleic Acids Research · doi:10.1093/nar/gkag114 · Cited by 3

A functional in vitro cell-free system for studying DNA repair in isolated nuclei

Guardamagna, I., Bassi, E., Savio, M., Perucca, P., Cazzalini, O., Prosperi, E., & Stivala, L. A. (2020) · Journal of Cell Science · doi:10.1242/jcs.240010 · Cited by 2

Enabling factor for cancer hallmark acquisition: Small nucleolar RNA host gene 17

Zhang, N., Sun, Y., Wang, T., Xu, X., & Cao, M. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.974939 · Cited by 2

Identification of a RAD51B enhancer variant for susceptibility and progression to glioma

Huang, L., Xu, W., Yan, D., Shi, X., Zhang, S., Chen, M., & Dai, L. (2023) · Cancer Cell International · doi:10.1186/s12935-023-03100-8 · Cited by 2

A Novel Inhibitor of Poly(ADP-Ribose) Polymerase-1 Inhibits Proliferation of a BRCA-Deficient Breast Cancer Cell Line via the DNA Damage–Activated cGAS–STING Pathway

Jin, Y., Wang, L., Jin, C., Zhang, N., Shimizu, S., Xiao, W., Guo, C., Liu, X., & Si, H. (2024) · Chemical Research in Toxicology · doi:10.1021/acs.chemrestox.3c00343 · Cited by 2

Comprehensive Liquid Biopsy Approaches for the Clinical Management of Lung Cancer Using Multiple Biological Matrices

Strati, A. D., Zavridou, M., Papavassiliou, K. A., & Papavassiliou, A. G. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms262311304 · Cited by 2

Rearrangements and Chromosome Translocations in Cancer

Bohlander, S. K., Kakadia, P. M., & Coysh, A. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.65105-x · Cited by 2

Targeting Enox1 in tumor stroma increases the efficacy of fractionated radiotherapy

Smith, C. A., Mont, S., Traver, G. L., Sekhar, K. R., Crooks, P. A., & Freeman, M. L. (2016) · Oncotarget · doi:10.18632/oncotarget.12845 · Cited by 2

MiRNAs in Cervical Cancer Radio- and Chemotherapy Response

López, J. A., & Granados‐López, A. J. (2017) · InTech eBooks · doi:10.5772/68010 · Cited by 2

Role of DNA Repair in Carcinogenesis and Cancer Therapeutics

Abbotts, R., Golato, T., & Wilson, D. M. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.65170-x · Cited by 3

Сytogenetical bioindication of pesticidal contamination

Cherednichenko, O., Pilyugina, A., & Nuraliev, S. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-90489-6.00010-0 · Cited by 4

Ku70 affects the frequency of chromosome translocation in human lymphocytes after radiation and T-cell acute lymphoblastic leukemia

Cheng, Z., Wang, Y., Guo, L., Li, J., Zhang, W., Zhang, C., Liu, Y., Huang, Y., & Xu, K. (2022) · Radiation Oncology · doi:10.1186/s13014-022-02113-3 · Cited by 3

The remodeling of Z-DNA in the mammalian germ line

Meng, Y., & Szabó, P. E. (2022) · Biochemical Society Transactions · doi:10.1042/bst20221015 · Cited by 2

Association of common BRCA1 variants with predisposition to breast tumors in Pakistan

Siddique, A., Fatima, W., & Shahid, N. (2023) · Annals of Human Genetics · doi:10.1111/ahg.12511 · Cited by 2

Genetic variation and radiation quality impact cancer promoting cellular phenotypes in response to HZE exposure

Sridharan, D., Enerio, S., Wang, C., LaBarge, M. A., Stampfer, M. R., & Pluth, J. M. (2018) · Life Sciences in Space Research · doi:10.1016/j.lssr.2018.10.002 · Cited by 2

Strategy to reduce radiation exposure in postoperative spinal computed tomography scans

Murthy, A., Kornel, E., & Neubardt, S. (2021) · Surgical Neurology International · doi:10.25259/sni_289_2020 · Cited by 2

Stereoselective Synthesis and Anticancer Activity of 2,6-Disubstituted trans-3-Methylidenetetrahydropyran-4-ones

Bartosik, T., Drogosz-Stachowicz, J., Janecka, A. E., Kędzia, J., Pacholczyk‐Sienicka, B., Szymański, J., Gach, K., & Janecki, T. (2022) · Materials · doi:10.3390/ma15093030 · Cited by 1

Single-molecule techniques in studying the molecular mechanisms of DNA synapsis in non-homologous end-joining repair

Jiang, Y., Zhao, C., Zhang, C., Li, W., Liu, D., & Zhao, B. (2024) · Biophysics Reports · doi:10.52601/bpr.2024.240043 · Cited by 1

New feature of hMEIOB and hSPATA22 binding to ssDNA from a single-molecule perspective

Xu, Y., Qu, W., Zhou, E.-C., Sun, Q., Gong, W., Xu, L., Lei, Y., Jia, Z., Shi, H., Zhang, X., et al. (2025) · Acta Biochimica et Biophysica Sinica · doi:10.3724/abbs.2025057 · Cited by 1

Targets and promising adjuvants for improving breast tumor response to radiotherapy

Yang, F., Song, H., Wu, W., & Guo, J. (2025) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2025.108582 · Cited by 1

DNA damage response inhibition is an early event in cadmium-induced breast carcinogenesis

Nail, A. N., Chavez, A. V., Bailey, A. N., Banerjee, M., Scott, J. L., Thomas, S. D., & States, J. C. (2025) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2025.117439 · Cited by 2

Short Inverted Repeats as Mutational Hotspots and Putative Drivers of Genome Instability in Osteosarcoma

Li, M., & Liang, C. (2025) · Genes · doi:10.3390/genes16101202 · Cited by 1

GenBlosum: On Determining Whether Cancer Mutations Are Functional or Random

Leyva, A., & Niazi, M. K. K. (2026) · Genes · doi:10.3390/genes17010055 · Cited by 1

Removal of heat-sensitive clustered damaged DNA sites is independent of double-strand break repair

Abramenkovs, A., & Stenerlöw, B. (2018) · PLoS ONE · doi:10.1371/journal.pone.0209594 · Cited by 1

Association of XRCC2 rs2040639 with the survival of patients with oral squamous cell carcinoma undergoing concurrent chemoradiotherapy

Senghore, T., Wang, W., Chien, H., Chen, Y.-X., Young, C., Huang, S., & Yeh, C. (2020) · Gene · doi:10.1016/j.gene.2020.145283 · Cited by 1

Hypoxic Stress Perturb DNA Repair Mechanisms Leading to Genetic Instability

Venkatesh, G. H. (2021) · Springer eBooks · doi:10.1007/978-981-15-4501-6_51-1 · Cited by 1

Characteristics and possible mechanisms of formation of microinversions distinguishing human and chimpanzee genomes

Potapova, N. A., Kondrashov, A. S., & Mirkin, S. M. (2022) · Scientific Reports · doi:10.1038/s41598-021-04621-w · Cited by 1

Hypoxic Stress Perturb DNA Repair Mechanisms Leading to Genetic Instability

Venkatesh, G. H. (2022) · Springer eBooks · doi:10.1007/978-981-15-9411-3_51 · Cited by 1

The Dependence of Compensation Dose on Systematic and Random Interruption Treatment Time in Radiation Therapy

Abolfath, R., Khalili, M., Senejani, A. G., Kodery, B., & Ivker, R. (2022) · Onco · doi:10.3390/onco2030015 · Cited by 1

Identification and Verification of a Glycolysis-Related lncRNA Prognostic Signature for Hepatocellular Carcinoma

Qiu, F., Yu, G., Li, M., Li, Z., Zhang, Q., Mu, X., Cheng, Y. B., Zhai, P., & Liu, Q. (2024) · Hormone and Metabolic Research · doi:10.1055/a-2314-0988 · Cited by 1

Chromosome instability: From molecular mechanisms to disease

de Cárcer, G., Huertas, P., & Lopez-Contreras, A. J. (2018) · DNA repair · doi:10.1016/j.dnarep.2018.04.006 · Cited by 1

Lack of associations between LIG3 gene polymorphisms and neuroblastoma susceptibility in Chinese children

Cheng, J., Wei, K., Xin, Y., Zhao, P., Zhang, J., Jia, W., & Zheng, B. (2019) · Journal of Cancer · doi:10.7150/jca.33605 · Cited by 1

Enhance PARPi Application beyond BRCA-Mutant Breast Cancer (BC): Facts Are Facts

Raimo, T. D., & Angelini, F. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9082377 · Cited by 1

Competing interactions modulate the activity of Sgs1 during DNA end resectionPreprint

Kasaciunaite, K., Fettes, F., Levikova, M., Daldrop, P., Ćejka, P., & Seidel, R. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/515791 · Cited by 1

Identification and characterization of novel genes involved in DNA double strand break repair process in the yeast Saccharomyces cerevisiae

Omidi, K. (2017) · Carleton University's Institutional Repository (MacOdrum Library, Carleton University) · doi:10.22215/etd/2017-11862 · Cited by 1

Analysis and characterization of chemo- and radiation therapy sensitizing strategies in tumours with focus on effects of phenothiazines on DNA damage response signalling

Zielinska-Chomej, K. (2015) · Figshare

Ubiquitination — An Evolving Role in DNA Repair

Boutou, E., Louka, M. A., Pappa, V., Stürzbecher, H.-W., Knippschild, U., Vlachodimitropoulos, D. G., & Vorgias, C. E. (2015) · InTech eBooks · doi:10.5772/61582

Analysis of the Genetic Requirements for Rad51-Mediated 3’ Polymerization during DNA Repair by Homologous Recombination

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