The DOI matches its Crossref record; 51 of the 51 references it cites were found in a registry or an index.
What made sesquiterpene lactones reach cancer clinical trials?
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Citations
Cites
In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2
Vassilev, L. T., Vu, B. T., Graves, B., Carvajal, D., Podlaski, F., Filipovic, Z., Kong, N., Kammlott, U., Lukacs, C., Klein, C., et al. (2004) · Science · doi:10.1126/science.1092472 · Cited by 4,661
Medicinal plants: Traditions of yesterday and drugs of tomorrow
Gurib-Fakim, A. (2006) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2005.07.008 · Cited by 2,391
Natural products in drug discovery
Harvey, A. L. (2008) · Drug Discovery Today · doi:10.1016/j.drudis.2008.07.004 · Cited by 1,832
Drug discovery from medicinal plants
Balunas, M. J., & Kinghorn, A. D. (2005) · Life Sciences · doi:10.1016/j.lfs.2005.09.012 · Cited by 1,810
Guzman, M. L., Rossi, R. M., Karnischky, L., Li, X., Peterson, D. R., Howard, D. S., & Jordan, C. T. (2005) · Blood · doi:10.1182/blood-2004-10-4135 · Cited by 678
Biological activities of sesquiterpene lactones
., E. R., Towers, G. H. N., & Mitchell, J. C. (1976) · Phytochemistry · doi:10.1016/s0031-9422(00)97430-2 · Cited by 595
Biological activities of sesquiterpene lactones
Picman, A. K. (1986) · Biochemical Systematics and Ecology · doi:10.1016/0305-1978(86)90101-8 · Cited by 538
Kwok, B. H. B., Koh, B., Ndubuisi, M. I., Elofsson, M., & Crews, C. M. (2001) · Chemistry & Biology · doi:10.1016/s1074-5521(01)00049-7 · Cited by 515
Tumor inhibitors. 69. Structure-cytotoxicity relations among the sesquiterpene lactones
Kupchan, S. M., Eakin, M. A., & Thomas, A. M. (1971) · Journal of Medicinal Chemistry · doi:10.1021/jm00294a001 · Cited by 486
Cysteine 38 in p65/NF-κB Plays a Crucial Role in DNA Binding Inhibition by Sesquiterpene Lactones
Garcı́a-Piñeres, A. J., Castro, V., Mora, G., Schmidt, T. J., Strunck, E., Pahl, H. L., & Merfort, I. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m101985200 · Cited by 407
Cited by
Jackson, P. A., Widen, J. C., Harki, D. A., & Brummond, K. M. (2017) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.6b00788 · Cited by 588
Therapeutic Potential of Certain Terpenoids as Anticancer Agents: A Scoping Review
Kamran, S., Sinniah, A., Abdulghani, M. A. M., & Alshawsh, M. A. (2022) · Cancers · doi:10.3390/cancers14051100 · Cited by 259
Sesquiterpene Lactones from Artemisia Genus: Biological Activities and Methods of Analysis
Ivanescu, B., Miron, A., & Corciova, A. (2015) · Journal of Analytical Methods in Chemistry · doi:10.1155/2015/247685 · Cited by 201
“Sesquiterpene lactones are a large group of natural compounds, found primarily in plants of Asteraceae family, with over 5000 structures reported to date.”
BackgroundSmall molecules regulating reactive oxygen species homeostasis for cancer therapy
Zhang, J., Duan, D., Song, Z., Liu, T., Hou, Y., & Fang, J. (2021) · Medicinal Research Reviews · doi:10.1002/med.21734 · Cited by 184
Jabbarzadegan, M., Rajayi, H., Mofazzal Jahromi, M. A., Yeganeh, H., Yousefi, M., Muhammad Hassan, Z., & Majidi, J. (2017) · Artificial Cells, Nanomedicine, and Biotechnology · doi:10.1080/21691401.2016.1178131 · Cited by 24
Metadata
- Authors
- Ghantous, A., Gali-Muhtasib, H., Vuorela, H., Saliba, N. A., & Darwiche, N.
- Venue
- Drug Discovery Today
- Publisher
- Elsevier BV
- Published
- 2010-08
- Volume
- 15
- Issue
- 15-16
- Pages
- 668-678
- ISSN
- 1359-6446 (ISSN-L)
- OpenAlex
- W2085827306
- Cited by
- 615
- References
- 51
- FWCI
- 9.75
- Type
- journal article
- Language
- en
- Open access
- closed
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- This page
- CoChat. (2026). Citation check: What made sesquiterpene lactones reach cancer clinical trials? https://app.cochat.ai/papers/10.1016/j.drudis.2010.06.002
- The paper
- Ghantous, A., Gali-Muhtasib, H., Vuorela, H., Saliba, N. A., & Darwiche, N. (2010). What made sesquiterpene lactones reach cancer clinical trials? Drug Discovery Today. https://doi.org/10.1016/j.drudis.2010.06.002
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
