Cited by 139Characterization and Applications of Magnetic NanoparticlesNanoplatforms for cancer theranosticsNanoparticle-Based Drug Delivery

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Next-generation superparamagnetic iron oxide nanoparticles for cancer theranostics

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Li, Kai, Nejadnik, Hossein, Daldrup-Link, Heike E.·2017·Drug Discovery Today

DOI 10.1016/j.drudis.2017.04.008PMC PMC5610947

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Abstract

Superparamagnetic iron oxide (SPIO) nanoparticles have been intensively studied for the development of contrast agents in MRI. First-generation SPIO nanoparticles had diagnostic capabilities only, whereas a new generation of SPIO nanoparticle has multifunctional characteristics for combined therapeutic and diagnostic applications. These theranostic nanoparticles hold great potential for image-guided cancer therapies. In particular, polymer-coated theranostic SPIO nanoparticles have enjoyed increasing attention as a result of good biocompatibility, biodegradability and versatile functionality endowed by polymeric matrices. This review provides an overview of recently developed polymer-coated multifunctional SPIO nanoparticles for cancer theranostics and discusses current challenges and future perspectives.

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Cancer statistics, 2016
Siegel, R. L., Miller, K. D., & Jemal, A. (2016) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.21332 · Cited by 16,003
A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs.
Matsumura, Y., & Maeda, H. (1986) · PubMed · Cited by 6,781
Stimuli-responsive nanocarriers for drug delivery
Mura, S., Nicolas, J., & Couvreur, P. (2013) · Nature Materials · doi:10.1038/nmat3776 · Cited by 6,289
Poly Lactic-co-Glycolic Acid (PLGA) as Biodegradable Controlled Drug Delivery Carrier
Makadia, H. K., & Siegel, S. J. (2011) · Polymers · doi:10.3390/polym3031377 · Cited by 4,816
Noninvasive detection of clinically occult lymph-node metastases in prostate cancer
Harisinghani, M. G., Barentsz, J., Hahn, P. F., Deserno, W. M., Tabatabaei, S., van de Kaa, C. H., de la Rosette, J., & Weissleder, R. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa022749 · Cited by 1,971
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Ulbrich, K., Holá, K., Šubr, V., Bakandritsos, A., Tuček, J., & Zbořil, R. (2016) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00589 · Cited by 1,759
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Le Tourneau, C., Delord, J.-P., Gonçalves, A., Gavoille, C., Dubot, C., Isambert, N., Campone, M., Trédan, O., Massiani, M.-A., Mauborgne, C., et al. (2015) · The Lancet Oncology · doi:10.1016/s1470-2045(15)00188-6 · Cited by 1,137
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Llovet, J. M., & Bruix, J. (2008) · Hepatology · doi:10.1002/hep.22506 · Cited by 1,011
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Li, K., & Liu, B. (2014) · Chemical Society Reviews · doi:10.1039/c4cs00014e · Cited by 1,000
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Authors: Li, K., Nejadnik, H., & Daldrup-Link, H. E.
Affiliations: Stanford Medicine (US)
Corresponding author: Li, Kai
Daldrup-Link, Heike E.
ORCID: Li, Kai
Nejadnik, Hossein
Daldrup-Link, Heike E.
Venue: Drug Discovery Today
Publisher: Elsevier BV
Published: 2017-09
Volume: 22
Issue: 9
Pages: 1421-1429
ISSN: 1359-6446 (ISSN-L)
DOI: 10.1016/j.drudis.2017.04.008
PMC: PMC5610947
OpenAlex: W2608879075
Cited by: 139
References: 62
Citations by year: 2026: 3 · 2025: 8 · 2024: 12 · 2023: 16 · 2022: 21 · 2021: 24 · 2020: 18 · 2019: 17 · 2018: 17 · 2017: 2
FWCI: 1.19
Type: journal article
Language: en
Open access: green
europepmc.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Drug Discovery Today (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: National Cancer Institute (NCI) (R21CA190196)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) (R21AR066302, 2R01AR054458)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (R01 HD081123-01A1)
Agency for Science, Technology and Research (A*STAR, Singapore)
Topics: Physical Sciences › Engineering › Biomedical Engineering › Characterization and Applications of Magnetic Nanoparticles
Physical Sciences › Engineering › Biomedical Engineering › Nanoplatforms for cancer theranostics
Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
Keywords: superparamagnetic iron oxide nanoparticles, theranostics, cancer theranostics, polymer-coated nanoparticles, multifunctional nanoparticles, MRI contrast agents, image-guided cancer therapy, biocompatibility, biodegradability
MeSH terms: Theranostic Nanomedicine, Animals, Ferric Compounds, Humans, Hyperthermia, Induced, Neoplasms, Phototherapy, Genetic Therapy, Metal Nanoparticles, Magnetic Phenomena

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Next-generation superparamagnetic iron oxide nanoparticles for cancer theranostics

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