Psychiatric disorders and attempted suicide among adolescents with substance use disorders
Abstract
Objective To determine the effects of psychiatric disorders on attempted suicide among adolescents with substance use disorders (SUD). Methods Age of onset for psychiatric disorders, age of first suicide attempt, and the relationship of psychiatric disorder with attempted suicide were investigated in a sample of 503 adolescents with DSM-IV defined SUD (age range: 12.2-19.0 years). Results Males who attempted suicide had a significantly earlier onset of alcohol use disorders (AUD) and significantly more mood, AUD, and disruptive behavior disorder symptoms compared to non-attempting males. Females who attempted suicide had a significantly earlier onset and higher counts of mood disorders and SUD symptoms compared to non-attempting females. Hazard analysis revealed that mood disorders represent the highest psychiatric risk for attempted suicide in both the genders. Attention deficit-hyperactivity disorder (ADHD) increased the risk for attempted suicide among males. The interaction of mood disorder and AUD increased the risk for attempted suicide among females. Conclusions Clinicians should closely monitor SUD adolescents for suicide risk and be aware of gender differences for suicidal behavior based on course and severity of psychiatric disorder in this population.
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ADHD has been found to increase suicide risk in SUD adolescents.
“ADHD has been found to increase suicide risk in SUD adolescents [210].”
From European consensus statement on diagnosis and treatment of adult ADHD: The European Network Adult ADHD (2010) · cites this paper as [210]
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- Authors
- Kelly, T. M., Cornelius, J. R., & Clark, D. B.
- Affiliations
- University of Pittsburgh (US)
- Corresponding author
- Kelly, Thomas M
- Venue
- Drug and Alcohol Dependence
- Publisher
- Elsevier BV
- Published
- 2004-01
- Volume
- 73
- Issue
- 1
- Pages
- 87-97
- ISSN
- 0376-8716 (ISSN-L)
- OpenAlex
- W2095120000
- Cited by
- 123
- References
- 46
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 1 · 2023: 1 · 2022: 6 · 2021: 3 · 2020: 8 · 2019: 3 · 2018: 6 · 2017: 1 · 2016: 2 · 2015: 4 · 2014: 8 · 2013: 5 · 2012: 8
- FWCI
- 7.32
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Drug and Alcohol Dependence (publishedVersion)
- PubMed (publishedVersion)
- Funders
- U.S. Public Health Service (K08-00280)
- National Institute on Alcohol Abuse and Alcoholism (R01-AA13370, P50-AA 08746, R01AA013370, K02AA00296, P50AA008746, K02AA000291, K02-AA00291)
- National Institute on Drug Abuse (R01 DA 14635, P50-DA 05605, R01DA014635, P50DA005605)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Sociology and Political Science › Homicide, Infanticide, and Child Abuse
- Keywords
- suicide attempts, adolescents, substance use disorders, alcoholism, mood disorders, attention deficit hyperactivity disorder, disruptive behavior disorders, age of onset, gender differences, suicide risk, psychiatric comorbidity
- MeSH terms
- Adolescent, Alcoholism, Female, Humans, Male, Pennsylvania, Sex Factors, Suicide, Attempted, Comorbidity, Proportional Hazards Models, Risk Assessment, Attention Deficit and Disruptive Behavior Disorders, Mood Disorders, Substance-Related Disorders
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