The relationship between crystalline methamphetamine use and methamphetamine dependence

McKetin, Rebecca; Kelly, Erin; McLaren, Jennifer

doi:10.1016/j.drugalcdep.2006.04.007

Cited by 149Substance Abuse Treatment and OutcomesYouth, Drugs, and ViolenceOpioid Use Disorder Treatment

The relationship between crystalline methamphetamine use and methamphetamine dependence

McKetin, Rebecca, Kelly, Erin, McLaren, Jennifer·2006·Drug and Alcohol Dependence

DOI 10.1016/j.drugalcdep.2006.04.007

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Abstract

Background The aim of the current study was to determine whether crystalline methamphetamine users are more dependent on methamphetamine than people who use other forms of the drug, and if so, whether this could be accounted for by their methamphetamine use history.Method A structured face-to-face interview was used to assess drug use patterns and demographics among a convenience sample of 309 regular methamphetamine users from Sydney, Australia. Dependence on methamphetamine in the past year was measured using the Severity of Dependence Scale. The use of crystalline methamphetamine in the past year was confirmed using a photographic identification sheet.Results Participants who had used crystalline methamphetamine in the past year were significantly more likely to be dependent on methamphetamine than participants who took only other forms of methamphetamine during this time (61% versus 39%). Methamphetamine dependence was also associated with injecting or smoking methamphetamine (67% and 58%, respectively versus 30% for intranasal or oral use), using methamphetamine more than weekly (68% versus 34%), having used the drug for more than 5 years (61% versus 36%), and having used 'base' methamphetamine in the past year (59% versus 39%). Crystalline methamphetamine use remained significantly associated with methamphetamine dependence after adjusting for these patterns of methamphetamine use.Conclusions Methamphetamine users who took crystalline methamphetamine in the past year were more likely to be dependent than methamphetamine users who had not taken the crystalline form of the drug during this time.

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A quarter of people using methamphetamine in McKetin et al's cross-sectional study experienced severe disability in their psychological functioning.
“McKetin et al 17 reported that a quarter of people using MA in their cross-sectional study experienced severe disability in their psychological functioning.”
From Protocol for a systematic review of psychological treatment for methamphetamine use: An analysis of methamphetamine use and mental health symptom outcomes (2017) · cites this paper as [17]

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Clinical and demographic characteristics of people who smoke versus inject crystalline methamphetamine in Australia: Findings from a pharmacotherapy trial
McKetin, R., Quinn, B., Higgs, P., Berk, M., Dean, O. M., Turner, A., Kelly, P. J., Lubman, D. I., Carter, G. L., Baker, A., et al. (2020) · Drug and Alcohol Review · doi:10.1111/dar.13183 · Cited by 15 · see citing works
Self-citation
Methamphetamine use in Melbourne, Australia: baseline characteristics of a prospective methamphetamine-using cohort and correlates of methamphetamine dependence
Quinn, B., Stoove, M. A., Papanastasiou, C., & Dietze, P. (2012) · Journal of Substance Use · doi:10.3109/14659891.2012.675400 · Cited by 29 · see citing works
Crystal methamphetamine smoking among regular ecstasy users in Australia: increases in use and associations with harm
Kinner, S. A., & Degenhardt, L. J. (2008) · Drug and Alcohol Review · doi:10.1080/09595230801919452 · Cited by 34 · see citing works
"--are you gonna wait until it kills you or are you gonna kill it?'' : narratives of individuals dependent on crystal methamphetamine
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Authors: McKetin, R., Kelly, E., & McLaren, J.
Affiliations: UNSW Sydney (AU)
Corresponding author: McKetin, Rebecca
ORCID: McKetin, Rebecca
Kelly, Erin
Venue: Drug and Alcohol Dependence
Publisher: Elsevier BV
Published: 2006-12
Volume: 85
Issue: 3
Pages: 198-204
ISSN: 0376-8716 (ISSN-L)
DOI: 10.1016/j.drugalcdep.2006.04.007
OpenAlex: W2000961004
Cited by: 145
References: 41
Citations by year: 2026: 6 · 2025: 2 · 2024: 6 · 2023: 5 · 2022: 9 · 2021: 13 · 2020: 4 · 2019: 3 · 2018: 7 · 2017: 7 · 2016: 9 · 2015: 10 · 2014: 8 · 2013: 7 · 2012: 14
FWCI: 4.39
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Drug and Alcohol Dependence (publishedVersion)
PubMed (publishedVersion)
Funders: Australian Government
National Drug Law Enforcement Research Fund
Topics: Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Social Sciences › Demography › Youth, Drugs, and Violence
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
Keywords: methamphetamine dependence, route of administration, injection, smoking, duration of drug use, Severity of Dependence Scale
MeSH terms: Adolescent, Adult, Central Nervous System Stimulants, Drug Administration Routes, Female, Humans, Male, Methamphetamine, Middle Aged, Severity of Illness Index, Substance-Related Disorders

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The relationship between crystalline methamphetamine use and methamphetamine dependence

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