Effect of a primary care based brief intervention trial among risky drug users on health-related quality of life
Open accessAbstract
Background Improvement in quality of life (QOL) is a long term goal of drug treatment. Although some brief interventions have been found to reduce illicit drug use, no trial among adult risky (moderate non-dependent) drug users has tested effects on health-related quality of life. Methods A single-blind randomized controlled trial of patients enrolled from February 2011 to November 2012 was conducted in waiting rooms of five federally qualified health centers. 413 adult primary care patients were identified as risky drug users using the WHO-ASSIST and 334 (81% response; 171 intervention, 163 control) consented to participate in the trial. Three-month follow-ups were completed by 261 patients (78%). Intervention patients received the QUIT intervention of brief clinician advice and up to two drug-use health telephone sessions. The control group received usual care and information on cancer screening. Outcomes were three-month changes in the Short Form Health Survey (SF-12) mental health component summary score (MCS) and physical health component summary score (PCS). Results The average treatment effect (ATE) was non-significant for MCS (0.2 points, p-value=0.87) and marginally significant for PCS (1.7 points, p-value=0.08). The average treatment effect on the treated (ATT) was 0.1 (p-value=0.93) for MCS and 1.9 (p-value=0.056) for PCS. The effect on PCS was stronger at higher (above median) baseline number of drug use days: ATE=2.7, p-value=0.04; ATT=3.21, p-value=0.02. Conclusions The trial found a marginally significant effect on improvement in PCS, and significant and stronger effect on the SF-12 physical component among patients with greater frequency of initial drug use.
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In a 2014 U.S. RCT among risky drug users, the trial found a marginally significant effect on improvement in PCS, and a significant and stronger effect on SF-12 physical component among patients with greater frequency of initial risky drug use.
“''The trial found a marginally significant effect on improvement in PCS, and significant and stronger effect on SF-12 physical component among patients with greater frequency of initial [risky] drug use.''”
From The Empirical Foundations of Telemedicine Interventions in Primary Care (2016) · cites this paper as [121]
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- Authors
- Baumeister, S. E., Gelberg, L., Leake, B. D., Yacenda-Murphy, J., Vahidi, M., & Andersen, R. M.
- Affiliations
- Universitätsmedizin Greifswald (DE)
- University of California, Los Angeles (US)
- Corresponding author
- Baumeister, Sebastian E.
- Venue
- Drug and Alcohol Dependence
- Publisher
- Elsevier BV
- Published
- 2014-09
- Volume
- 142
- Pages
- 254-261
- ISSN
- 0376-8716 (ISSN-L)
- PMC
- PMC4127148
- OpenAlex
- W1969954835
- Semantic Scholar
- 3276194fe74863467c66ffb96df9b64da3e4ba97
- Cited by
- 24
- References
- 57
- Citations by year
- 2025: 1 · 2024: 2 · 2023: 7 · 2021: 1 · 2020: 2 · 2019: 1 · 2018: 1 · 2017: 1 · 2016: 4 · 2015: 4
- FWCI
- 2.27
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Drug and Alcohol Dependence (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- Northwestern University
- National Institutes of Health (4p20md000182-15, 5p20md000148-05)
- VA Greater Los Angeles Healthcare System
- National Institute on Drug Abuse (P30DA027828, R01DA022445, DA027828)
- National Center on Minority Health and Health Disparities
- National Institute on Minority Health and Health Disparities (P20-MD000148, P20-MD000182)
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
- Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
- Keywords
- brief intervention, health-related quality of life, primary care, telephone counseling, physical health, mental health, drug use frequency, federally qualified health centers
- MeSH terms
- Adult, Counseling, Female, Health Status, Humans, Male, Middle Aged, Primary Health Care, Quality of Life, Risk-Taking, Single-Blind Method, Treatment Outcome, Remote Consultation, Drug Users
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