Burden and psychological symptoms among caregivers of patients with solid tumor cancers
Abstract
Purpose To evaluate factors associated with burden reported by caregivers of people undergoing treatment for solid tumor cancers. Methods A secondary analysis of baseline data collected in a cancer symptom management trial was conducted guided by the Organizing Framework for Caregiver Interventions. A total of 349 caregivers completed the Caregiver Reaction Assessment Tool evaluating caregiver burden; Bayliss Comorbidity Tool; and PROMIS-29 version1.0-Anxiety and Depression Short Forms. Multivariable linear models were used to examine the associations of Caregiver Reaction Assessment Tool subscales (caregiver self-esteem, family support, financial, schedule, and health burden) with caregiver sociodemographic characteristics, comorbidities, anxiety, and depression. Results The majority of caregivers were female and spouses/partners who resided with the patient. Being female, Asian, a spouse of the patient, employed, and having a higher level of anxiety and depressive symptoms were significantly associated with lower caregiver self-esteem, and higher perceived schedule and health burden. Caregiver anxiety and depressive symptoms were also significantly associated with lack of family support and higher financial burden. Conclusions Clinicians should consider factors that contribute to higher perceived burden for caregivers when they are engaged in home-based supportive care for patients undergoing cancer treatment.
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Otras publicaciones reportan características similares en términos de sexo, relación con el paciente, ingresos económicos bajos (menores a USD 500) y un alto grado de compromiso del cuidador manifestado por el número de horas al día dedicadas a su atención.
“Otras publicaciones reportan características similares en términos de sexo, relación con el paciente, ingresos económicos bajos (menores a USD 500) (42-44) y un alto grado de compromiso del cuidador por atender a su familiar enfermo, manifestado por el número de horas al día dedicadas a su atención (45, 46).”
From Factores relacionados con sobrecarga del cuidador informal de pacientes con cáncer avanzado (2024) · cites this paper as [43]
Cites
Given, C. W., Given, B. A., Stommel, M., Collins, C. E., King, S., & Franklin, S. (1992) · Research in Nursing & Health · doi:10.1002/nur.4770150406 · Cited by 893 · see citing works
Self-citationCaregiving and the Experience of Subjective and Objective Burden
Montgomery, R. J. V., Gonyea, J. G., & Hooyman, N. R. (1985) · Family Relations · doi:10.2307/583753 · Cited by 733 · see citing works
Caregiving Burden, Stress, and Health Effects Among Family Caregivers of Adult Cancer Patients
Bevans, M., & Sternberg, E. M. (2012) · JAMA · doi:10.1001/jama.2012.29 · Cited by 620 · see citing works
Burden and Depression Among Caregivers of Patients With Cancer at the End of Life
Given, B. A., Wyatt, G. K., Given, C. W., Sherwood, P. R., Gift, A. G., DeVoss, D. N., & Rahbar, M. H. (2004) · Oncology nursing forum · doi:10.1188/04.onf.1105-1117 · Cited by 487 · see citing works
Self-citationPhysical, Psychosocial, Relationship, and Economic Burden of Caring for People With Cancer: A Review
Girgis, A., Lambert, S., Johnson, C., Waller, A., & Currow, D. (2013) · Journal of Oncology Practice · doi:10.1200/jop.2012.000690 · Cited by 462 · see citing works
Family caregiver burden, skills preparedness, and quality of life in non-small cell lung cancer
Grant, M., Sun, V., Fujinami, R., Sidhu, R., Otis-Green, S., Juarez, G., Klein, L., & Ferrell, B. (2013) · Oncology Nursing Forum · doi:10.1188/13.onf.337-346 · Cited by 212 · see citing works
Family and Caregiver Needs over the Course of the Cancer Trajectory
Given, B. A., Given, C. W., & Sherwood, P. R. (2012) · The Journal of Supportive Oncology · doi:10.1016/j.suponc.2011.10.003 · Cited by 194 · see citing works
Self-citationBayliss, E. A., Ellis, J., & Steiner, J. F. (2008) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2008.05.002 · Cited by 169 · see citing works
Quantifying the burden of informal caregiving for patients with cancer in Europe
Goren, A., Gilloteau, I., Lees, M., & DiBonaventura, M. (2014) · Supportive Care in Cancer · doi:10.1007/s00520-014-2122-6 · Cited by 157 · see citing works
Factors Associated With Higher Caregiver Burden Among Family Caregivers of Elderly Cancer Patients
Ge, L., & Mordiffi, S. Z. (2016) · Cancer Nursing · doi:10.1097/ncc.0000000000000445 · Cited by 149 · see citing works
Caregiver symptom burden: The risk of caring for an underserved patient with advanced cancer
Palos, G. R., Mendoza, T. R., Liao, K.-P. E., Anderson, K. O., García-González, A., Hahn, K. M. E., Nazario, A., Ramondetta, L. M., Valero, V., Lynch, G. R., et al. (2010) · Cancer · doi:10.1002/cncr.25695 · Cited by 146 · see citing works
Wyatt, G. K., Sikorskii, A. E., Rahbar, M. H., Victorson, D. E., & You, M. (2012) · Oncology nursing forum · doi:10.1188/12.onf.568-577 · Cited by 120 · see citing works
Self-citationHoutven, C. H. V., Voils, C. I., & Weinberger, M. (2011) · BMC Geriatrics · doi:10.1186/1471-2318-11-77 · Cited by 99 · see citing works
Informal caregiver burden for solid tumour cancer patients: a review and future directions
Thana, K., Lehto, R., Sikorskii, A., & Wyatt, G. (2021) · Psychology & Health · doi:10.1080/08870446.2020.1867136 · Cited by 97 · see citing works
Self-citationDepression Symptoms in Cancer Caregivers
Rivera, H. R. (2009) · Clinical journal of oncology nursing · doi:10.1188/09.cjon.195-202 · Cited by 84 · see citing works
Maguire, R., Hanly, P. A., Hyland, P., & Sharp, L. (2016) · European Journal of Cancer Care · doi:10.1111/ecc.12527 · Cited by 67 · see citing works
The burden of brain tumor: a single-institution study on psychological patterns in caregivers
Finocchiaro, C. Y., Petruzzi, A., Lamperti, E., Botturi, A., Gaviani, P., Silvani, A., Sarno, L., & Salmaggi, A. (2011) · Journal of Neuro-Oncology · doi:10.1007/s11060-011-0726-y · Cited by 65 · see citing works
Stenberg, U., Cvancarova, M., Ekstedt, M., Olsson, M., & Ruland, C. M. (2014) · Social Work in Health Care · doi:10.1080/00981389.2013.873518 · Cited by 60 · see citing works
Wyatt, G. K., Sikorskii, A. E., Tešnjak, I., Frambes, D., Holmstrom, A. J., Luo, Z., Victorson, D. E., & Tamkus, D. M. (2017) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2017.07.037 · Cited by 60 · see citing works
Self-citationHu, X.-L., Peng, X.-C., Su, Y.-L., & Huang, W.-X. (2018) · European Journal of Oncology Nursing · doi:10.1016/j.ejon.2018.11.003 · Cited by 60 · see citing works
Unmet needs of family cancer caregivers predict quality of life in long-term cancer survivorship
Kim, Y., & Carver, C. S. (2019) · Journal of Cancer Survivorship · doi:10.1007/s11764-019-00794-6 · Cited by 60 · see citing works
Jeong, A., & An, J. Y. (2017) · PLoS ONE · doi:10.1371/journal.pone.0189808 · Cited by 56 · see citing works
Moscati, A., Flint, J., & Kendler, K. (2015) · Depression and Anxiety · doi:10.1002/da.22432 · Cited by 51 · see citing works
Leow, M. Q. H., & Chan, S. W. (2016) · Cancer Nursing · doi:10.1097/ncc.0000000000000354 · Cited by 48 · see citing works
Levels of Care Burden and Self-efficacy for Informal Caregiver of Patients With Cancer
Yıldız, E., Karakaş, S. A., Güngörmüş, Z., & Cengiz, M. (2016) · Holistic Nursing Practice · doi:10.1097/hnp.0000000000000185 · Cited by 48 · see citing works
Contextual and Cultural Influences on Caregivers of Hispanic Cancer Survivors
Badger, T. A., Sikorskii, A. E., & Segrin, C. G. (2019) · Seminars in Oncology Nursing · doi:10.1016/j.soncn.2019.06.008 · Cited by 33 · see citing works
Self-citationHome-based mindfulness therapy for lung cancer symptom management: a randomized feasibility trial
Lehto, R. H., Wyatt, G. K., Sikorskii, A. E., Tešnjak, I., & Hankin, V. M. (2015) · Psycho-Oncology · doi:10.1002/pon.3755 · Cited by 27 · see citing works
Self-citationSherwood, P. R., Given, B. A., Given, C. W., Sikorskii, A. E., You, M., & Prince, J. (2011) · Supportive Care in Cancer · doi:10.1007/s00520-011-1295-5 · Cited by 27 · see citing works
Self-citationFrambes, D., Sikorskii, A. E., Tešnjak, I., Wyatt, G. K., Lehto, R. H., & Given, B. A. (2017) · Oncology nursing forum · doi:10.1188/17.onf.596-605 · Cited by 18 · see citing works
Self-citationWyatt, G. K., Lehto, R. H., & Sender, J. S. (2019) · Seminars in Oncology Nursing · doi:10.1016/j.soncn.2019.06.005 · Cited by 17 · see citing works
Self-citationUsing SMART design to improve symptom management among cancer patients: A study protocol
Sikorskii, A. E., Wyatt, G. K., Lehto, R. H., Victorson, D. E., Badger, T. A., & Pace, T. W. W. (2017) · Research in Nursing & Health · doi:10.1002/nur.21836 · Cited by 14 · see citing works
Self-citationFamily carer reactions and their related factors among Taiwanese with hospitalized relatives
Yeh, P., & Chang, Y. (2011) · Journal of Advanced Nursing · doi:10.1111/j.1365-2648.2011.05904.x · Cited by 10 · see citing works
Wyatt, G. K., Sikorskii, A. E., & You, M. (2013) · PubMed · Cited by 5 · see citing works
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Lefebvre, M., & Foulkes, W. D. (2013) · Current Oncology · doi:10.3747/co.21.1579 · Cited by 122 · see citing works
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Fakih, M., & Vincent, M. (2010) · Current Oncology · doi:10.3747/co.v17is1.615 · Cited by 147 · see citing works
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Morgan, S. P., Lengacher, C. A., & Rodriguez, C. S. (2022) · European Journal of Oncology Nursing · doi:10.1016/j.ejon.2022.102152 · Cited by 42 · see citing works
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Alanazi, M. O., Patano, A., Bente, G., Mason, A. J., Goldstein, D., Parsnejad, S., Wyatt, G. K., & Lehto, R. H. (2023) · Current Oncology · doi:10.3390/curroncol30070448 · Cited by 20 · see citing works
Self-citationAllison, K. R., Power, R., Ussher, J. M., Perz, J., the Out with Cancer Study Team, Hawkey, A., Parton, C., Watson, L., Hickey, M., Dowsett, G. W., et al. (2024) · BMC Cancer · doi:10.1186/s12885-023-11732-2 · Cited by 15 · see citing works
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Lehto, R. H., Wyatt, G. K., Sender, J. S., & Miller, S. E. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph182111124 · Cited by 14 · see citing works
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Nishibori, M. (2007) · Current Oncology · doi:10.3747/co.2007.159 · Cited by 12 · see citing works
Grivel, C., Nizet, P., MARTIN, M., Pécout, S., Lepeintre, A., Touchefeu, Y., Prot‐Labarthe, S., Evin, A., & Huon, J. (2023) · PLoS ONE · doi:10.1371/journal.pone.0287335 · Cited by 8 · see citing works
Wahad, A. A. A., Elran‐Barak, R., Furer, M., Kamir, G. A., & Horowitz, N. A. (2024) · Blood Advances · doi:10.1182/bloodadvances.2024012915 · Cited by 8 · see citing works
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Ao, M., Xu, K., Pan, Y., Wang, S., & Fu, G. (2023) · Endocrine Metabolic & Immune Disorders - Drug Targets · doi:10.2174/0118715303238500231101051257 · Cited by 3 · see citing works
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Patano, A., Lehto, R. H., & Wyatt, G. K. (2025) · BMJ Open · doi:10.1136/bmjopen-2025-111717 · Cited by 2 · see citing works
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Thana, K., Miller, M. E., Chintanawat, R., & Reangsing, C. (2023) · Research Square · doi:10.21203/rs.3.rs-3746336/v1 · Cited by 1 · see citing works
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- Authors
- Thana, K., Sikorskii, A., Lehto, R., Given, C., & Wyatt, G.
- Affiliations
- Chiang Mai University (TH)
- Michigan State University (US)
- Corresponding author
- Thana, Kanjana
- Sikorskii, Alla
- Lehto, Rebecca
- Given, Charles
- Wyatt, Gwen
- Venue
- European Journal of Oncology Nursing
- Publisher
- Elsevier BV
- Published
- 2021-06
- Volume
- 52
- Pages
- 101979
- ISSN
- 1462-3889 (ISSN-L)
- OpenAlex
- W3164653997
- Cited by
- 22
- References
- 33
- Citations by year
- 2025: 3 · 2024: 4 · 2023: 6 · 2022: 4 · 2021: 2 · 2013: 1
- FWCI
- 6.25
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- European Journal of Oncology Nursing (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Foundation for the National Institutes of Health
- National Cancer Institute (R01 CA 193706)
- Michigan State University
- Chiang Mai University
- Topics
- Health Sciences › Health Professions › Pharmacy › Nursing care and research
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Social Sciences › Sociology and Political Science › Family Support in Illness
- Keywords
- caregiver burden, caregiver anxiety, caregiver depression, caregiver self-esteem, family support, financial burden, health burden, cancer symptom management, sociodemographic factors, comorbidities
- MeSH terms
- Anxiety, Cross-Sectional Studies, Depression, Female, Humans, Male, Neoplasms, Caregivers
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