Quality of life in subgroups of individuals with whiplash associated disorders
Abstract
BACKGROUND: The term whiplash associated disorders (WAD) includes a wide range of complaints, with neck pain as predominating symptom. Living with long term pain influences quality of life. In previous studies of other chronic pain patients, subgrouping has been made according to thermal pain thresholds measured in quantitative sensory testing (QST). AIMS: The aims of the present study are threefold, (1) to evaluate thermal pain thresholds and health related quality of life in WAD patients compared to healthy pain-free individuals, (2) to explore whether subgrouping of the WAD patients is possible according to thermal pain thresholds over trapezius, and if so (3) to explore differences between the subgroups. METHODS: Twenty-six patients with WAD and 18 healthy pain-free controls took part in the study. Thermal pain thresholds were measured in two sites (over the thenar and the trapezius muscle) using quantitative sensory testing (QST). Health related quality of life (HRQoL) was assessed using the SF-36. The visual analogue scale was used to rate pain intensity and unpleasantness related to the experimental situation. RESULTS: WAD patients are more sensitive to thermal pain, and scored lower on the SF-36 in all scales when compared with healthy pain-free individuals. After analyzing clusters (K-means algorithm) two subgroups of WAD emerge, pain insensitive and pain sensitive. The pain insensitive group differed significantly from the pain sensitive group in the Role Emotional subscale of SF-36 (p=0.025). CONCLUSIONS: Thermal pain hyperalgesia, especially for cold, seems to be a determinant for subgrouping WAD patients. These results support that such a classification of a heterogenous group could be of importance in tailoring treatment and early interventions.
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The overall poor quality of life of the patients in this study, according to the SF-36, was consistent with previously published pain studies but distinctively lower than the Swedish population norm.
“The overall poor quality of life of the patients in this study, according to the SF-36, was consistent with previously published pain studies [67–69] but distinctively lower than the Swedish population norm [38].”
From Chronic pain and sex-differences; women accept and move, while men feel blue (2017) · cites this paper as [69]
Cites
The validation of visual analogue scales as ratio scale measures for chronic and experimental pain
Price, D. D., McGrath, P. A., Rafii, A., & Buckingham, B. (1983) · Pain · doi:10.1016/0304-3959(83)90126-4 · Cited by 3,921 · see citing works
A critical review of visual analogue scales in the measurement of clinical phenomena
Wewers, M. E., & Lowe, N. K. (1990) · Research in Nursing & Health · doi:10.1002/nur.4770130405 · Cited by 2,580 · cited 2× · see citing works
“For ratings of experienced pain intensity and pain unpleasantness in the experimental setting, a visual analogue scale was used (Huskisson, 1983; Wewer and Lowe, 1990).”
MethodSullivan, M., Karlsson, J., & Ware, J. E. (1995) · Social Science & Medicine · doi:10.1016/0277-9536(95)00125-q · Cited by 1,315 · see citing works
The reliability of a linear analogue for evaluating pain
REVILL, S. I., ROBINSON, J. O., Rosen, M. A., & Hogg, M. (1976) · Anaesthesia · doi:10.1111/j.1365-2044.1976.tb11971.x · Cited by 1,257 · see citing works
Visual analogue scales: measurement of subjective phenomena.
Gift, A. G. (1989) · PubMed · Cited by 1,138 · see citing works
Method for quantitative estimation of thermal thresholds in patients.
Fruhstorfer, H., Lindblom, U., & Schmidt, W. C. (1976) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.39.11.1071 · Cited by 785 · see citing works
Pain Measurement and Assessment
Melzack, R. (1983) · Medical Entomology and Zoology · Cited by 575 · see citing works
Pain measurement and assessment
Pearce, S. A. (1984) · Pain · doi:10.1016/0304-3959(84)90089-7 · Cited by 360 · see citing works
The use of pain scales in assessing the efficacy of analgesics in post-operative dental pain
Seymour, R. A. (1982) · European Journal of Clinical Pharmacology · doi:10.1007/bf00605995 · Cited by 258 · see citing works
Characterization of Acute Whiplash-Associated Disorders
Sterling, M. M., Jull, G. A., Vicenzino, B., & Kenardy, J. A. (2004) · Spine · doi:10.1097/01.brs.0000105535.12598.ae · Cited by 192 · see citing works
Hurtig, I., Raak, R., Kendall, S., Gerdle, B., & Wahren, L. (2001) · The Clinical Journal of Pain · doi:10.1097/00002508-200112000-00005 · Cited by 177 · see citing works
Reduced cold pressor pain tolerance in non‐recovered whiplash patients: a 1‐year prospective study
Kasch, H., Qerama, E., Bach, F. W., & Jensen, T. S. (2004) · European Journal of Pain · doi:10.1016/j.ejpain.2004.11.011 · Cited by 164 · see citing works
Söderlund, A., Olerud, C., & Lindberg, P. (2000) · Clinical Rehabilitation · doi:10.1191/0269215500cr348oa · Cited by 136 · see citing works
Psychiatry of whiplash neck injury
Mayou, R., & Bryant, B. (2002) · The British Journal of Psychiatry · doi:10.1192/bjp.180.5.441 · Cited by 108 · see citing works
Extracervical Symptoms After Whiplash Trauma
Magnússon, T. (1994) · Cephalalgia · doi:10.1046/j.1468-2982.1994.014003223.x · Cited by 74 · see citing works
Buitenhuis, J., Spanjer, J., & Fidler, V. (2003) · Spine · doi:10.1097/01.brs.0000058720.56061.2a · Cited by 72 · see citing works
Whiplash and post-traumatic stress disorder
Jaspers, J. (1998) · Disability and Rehabilitation · doi:10.3109/09638289809166101 · Cited by 65 · see citing works
Whiplash-associated disorders – predicting disability from a process-oriented perspective of coping
Söderlund, A., & Lindberg, P. (2003) · Clinical Rehabilitation · doi:10.1191/0269215503cr566oa · Cited by 64 · see citing works
Söderlund, A., & Denison, E. (2005) · European Journal of Pain · doi:10.1016/j.ejpain.2005.01.015 · Cited by 60 · see citing works
A Cross-Cultural Comparison Between Canada and Germany of Symptom Expectation for Whiplash Injury
Ferrari, R., & Lang, C. J. G. (2005) · Journal of Spinal Disorders & Techniques · doi:10.1097/01.bsd.0000138214.70260.91 · Cited by 51 · see citing works
Mayou, R., & Radanov, B. P. (1996) · Journal of Psychosomatic Research · doi:10.1016/0022-3999(95)00586-2 · Cited by 49 · see citing works
Thermal Thresholds and Catastrophizing in Individuals with Chronic Pain after Whiplash Injury
Raak, R. I., & Wallin, M. (2006) · Biological Research For Nursing · doi:10.1177/1099800406291078 · Cited by 30 · see citing works
Self-citationFactors Influencing Neck Pain Intensity in Whiplash-Associated Disorders
Holm, L. W., Carroll, L., Cassidy, J. D., & Ahlbom, A. (2006) · Spine · doi:10.1097/01.brs.0000199901.52053.87 · Cited by 25 · see citing works
Sprain of the neck: Quality of life and psychological functioning. A 4-year retrospective study
Versteegen, G. J., Dijkstra, P. U., Jaspers, J. P. C., Meijler, W. J., ten Duis, H. J., & Klip, E. C. (2003) · Quality of Life Research · doi:10.1023/a:1023276531487 · Cited by 23 · see citing works
Raak, R. I., Wikblad, K. F., Raak, A., Carlsson, M., & Wahren, L. K. (2002) · Rehabilitation Nursing · doi:10.1002/j.2048-7940.2002.tb01999.x · Cited by 18 · see citing works
Neurogenic flare responses in chronic rheumatic pain syndromes.
Helme, R. D., Littlejohn, G., & Weinstein, C. (1987) · PubMed · Cited by 16 · see citing works
Stress coping strategies in thermal pain sensitive and insensitive healthy subjects
Raak, R. I., & Wahren, L. K. (2001) · International Journal of Nursing Practice · doi:10.1046/j.1440-172x.2001.00258.x · Cited by 15 · see citing works
Chronic Pain and Whiplash Associated Disorders: Rehabilitation and Secondary Prevention
Turk, D. C. (2003) · Pain Research and Management · doi:10.1155/2003/437163 · Cited by 12 · see citing works
Physiotherapy management, coping and outcome prediction in whiplash associated disorders (WAD).
Söderlund, A. (2001) · KTH Publication Database DiVA (KTH Royal Institute of Technology) · Cited by 7 · see citing works
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Louw, A., Diener, I., Butler, D. S., & Puentedura, E. J. (2011) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2011.07.198 · Cited by 686 · see citing works
Chronic pain and sex-differences; women accept and move, while men feel blue
Rovner, G. S., Sunnerhagen, K. S., Björkdahl, A., Gerdle, B., Börsbo, B., Johansson, F., & Gillanders, D. (2017) · PLOS ONE · doi:10.1371/journal.pone.0175737 · Cited by 179 · see citing works
Sullivan, M. J. L., Davidson, N., Garfinkel, B., Siriapaipant, N., & Scott, W. (2009) · Psychological Injury and Law · doi:10.1007/s12207-009-9055-2 · Cited by 116 · see citing works
Juul, T., Langberg, H., Enoch, F., & Søgaard, K. (2013) · BMC Musculoskeletal Disorders · doi:10.1186/1471-2474-14-339 · Cited by 104 · see citing works
Meeus, M. (2015) · Pain Physician · doi:10.36076/ppj.2015/18/e389 · Cited by 88 · see citing works
Sterling, M. M., Pedler, A. R., Chan, C. L., Puglisi, M., Vuvan, V., & Vicenzino, B. (2009) · Manual Therapy · doi:10.1016/j.math.2009.09.004 · Cited by 86 · see citing works
Stone, A. M., Vicenzino, B., Lim, E. C. W., & Sterling, M. M. (2012) · Manual Therapy · doi:10.1016/j.math.2012.07.009 · Cited by 81 · see citing works
Cederberg, J. T., Cernvall, M., Dahl, J., von Essen, L., & Ljungman, G. (2016) · International Journal of Behavioral Medicine · doi:10.1007/s12529-015-9494-y · Cited by 79 · see citing works
Alahmari, K. A., Reddy, R. S., Samuel, P. S., Ahmad, I., Kakaraparthi, V. N., & Mahtab, M. (2017) · Brazilian Journal of Physical Therapy · doi:10.1016/j.bjpt.2017.05.003 · Cited by 71 · see citing works
Wallin, M., Liedberg, G., Börsbo, B., & Gerdle, B. U. C. (2011) · Clinical Journal of Pain · doi:10.1097/ajp.0b013e318226c3fd · Cited by 57 · see citing works
Self-citationSigns of ongoing inflammation in female patients with chronic widespread pain
Gerdle, B. U. C., Ghafouri, B., Ghafouri, N., Bäckryd, E., & Gordh, T. (2017) · Medicine · doi:10.1097/md.0000000000006130 · Cited by 53 · see citing works
Hendriks, E., Voogt, L., Lenoir, D., Coppieters, I., & Ickmans, K. (2020) · Pain medicine (Malden, Mass.) · doi:10.1093/pm/pnaa276 · Cited by 43 · see citing works
Jónsdóttir, Þ., Aspelund, T., Jónsdóttir, H., & Gunnarsdóttir, S. (2013) · Pain Management Nursing · doi:10.1016/j.pmn.2013.07.005 · Cited by 35 · see citing works
Jónsdóttir, Þ., Jónsdóttir, H., Líndal, E., Óskarsson, G. K., & Gunnarsdóttir, S. (2014) · Health Expectations · doi:10.1111/hex.12245 · Cited by 26 · see citing works
Health, Social, and Economic Consequences of Neck Injuries
Jennum, P., Kjellberg, J., Ibsen, R., & Bendix, T. (2012) · Spine · doi:10.1097/brs.0b013e3182819203 · Cited by 25 · see citing works
Convergent and Discriminant Validity of the Serbian Version of the Central Sensitization Inventory
Knežević, A., Neblett, R., Čolović, P., Jeremić-Knežević, M., Ignjatović, V. B., Klasnja, A., Pantelinac, S., & Pjević, M. (2020) · Pain Practice · doi:10.1111/papr.12900 · Cited by 24 · see citing works
Beltrán-Alacreu, H., López‐de‐Uralde‐Villanueva, I., Calvo‐Lobo, C., Touche, R. L., Cano‐de‐la‐Cuerda, R., Gil‐Martínez, A., Ayuso, D. F., & Fernández‐Carnero, J. (2018) · Patient Preference and Adherence · doi:10.2147/ppa.s162702 · Cited by 26 · see citing works
Roman, M., Highland, J., Retherford, D. M., Pan, A. Y., Panepinto, J. A., & Brandow, A. M. (2020) · Pediatric Blood & Cancer · doi:10.1002/pbc.28698 · Cited by 20 · see citing works
Börsbo, B., Liedberg, Wallin, & Gerdle, B. U. C. (2012) · Journal of Pain Research · doi:10.2147/jpr.s37062 · Cited by 19 · see citing works
Rydstad, M., Schult, M., & Löfgren, M. (2010) · Disability and Rehabilitation · doi:10.3109/09638281003734425 · Cited by 18 · see citing works
Jónsdóttir, Þ., Gunnarsdóttir, S., Óskarsson, G. K., & Jónsdóttir, H. (2016) · Pain Management Nursing · doi:10.1016/j.pmn.2016.07.001 · Cited by 17 · see citing works
Neck Pain: Much More Than a Psychosocial Condition
Sterling, M. M. (2009) · Journal of Orthopaedic and Sports Physical Therapy · doi:10.2519/jospt.2009.0113 · Cited by 17 · see citing works
Carlesso, L. C., Walton, D. M., & MacDermid, J. C. (2011) · Disability and Rehabilitation · doi:10.3109/09638288.2011.632467 · Cited by 16 · see citing works
Lenoir, D., Willaert, W., Ickmans, K., Bernaers, L., Nijs, J., Malfliet, A., Danneels, L. A., Leysen, L., Pauw, R. D., Cagnie, B. J., et al. (2021) · Clinical Journal of Pain · doi:10.1097/ajp.0000000000001013 · Cited by 9 · see citing works
Stensson, N., Ghafouri, B., Ghafouri, N., & Gerdle, B. U. C. (2016) · Molecular Pain · doi:10.1177/1744806916662886 · Cited by 9 · see citing works
Peilot, B., Andréll, P., Mannerkorpi, K., & Mannheimer, C. (2010) · Disability and Rehabilitation · doi:10.3109/09638281003734383 · Cited by 8 · see citing works
Pina, D., Puente-López, E., Hernández, J. A. R., Ruíz-Cabello, A. L., Aguerrevere, L. E., & Magalhães, T. (2021) · Frontiers in Psychology · doi:10.3389/fpsyg.2021.716513 · Cited by 6 · see citing works
Hendriks, E. P., Coppieters, I., Voogt, L. P., Cools, W., & Ickmans, K. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13020482 · Cited by 5 · see citing works
Discriminative validity of sensory evaluation in a whiplash-associated disorder II population
Rushton, A. B., Wright, C. C., Kontakiotis, N., Mystrakis, A., Frydas, D., & Heneghan, N. R. (2014) · International Journal of Therapy and Rehabilitation · doi:10.12968/ijtr.2014.21.10.460 · Cited by 5 · see citing works
Deutsche transkulturelle Übersetzung des Injustice Experience Questionnaire
Niederstrasser, N. G., Steiger, B., Welsch, K., Hartmann, S., Nilges, P., Ljutow, A., & Ettlin, D. A. (2018) · Der Schmerz · doi:10.1007/s00482-018-0329-z · Cited by 5 · see citing works
Gerdle, B. U. C., Wåhlén, K., Gordh, T., & Ghafouri, B. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10163652 · Cited by 3 · see citing works
Development and evaluation of a novel intervention for rehabilitation following whiplash injury
Wiangkham, T. (2017) · University of Birmingham Institutional Research Archive (University of Birmingham) · Cited by 3 · see citing works
Perceived injustice in patients with chronic pain
Wolter, T., & Kleinmann, B. (2025) · BioPsychoSocial Medicine · doi:10.1186/s13030-025-00328-w · Cited by 1 · see citing works
Edeni, K. (2013) · University of Birmingham Institutional Research Archive (University of Birmingham)
Traumatic brain injuries and whiplash injuries : epidemiology and long-term consequences
Styrke, J. (2012) · KTH Publication Database DiVA (KTH Royal Institute of Technology)
Louw, A. (2018) · Elsevier eBooks · doi:10.1016/b978-0-323-39370-6.00071-8
Manske, R. C. (2011) · Elsevier eBooks · doi:10.1016/b978-0-323-05590-1.00016-4
- Authors
- Wallin, M. K. M., & Raak, R. I.
- Affiliations
- Linköping University (SE)
- Corresponding author
- Wallin, Mia K.M.
- Venue
- European Journal of Pain
- Publisher
- Wiley
- Published
- 2008-10
- Volume
- 12
- Issue
- 7
- Pages
- 842-849
- ISSN
- 1090-3801 (ISSN-L)
- 1532-2149
- OpenAlex
- W1967518537
- Cited by
- 37
- References
- 29
- Citations by year
- 2025: 1 · 2024: 1 · 2021: 3 · 2020: 3 · 2018: 3 · 2017: 4 · 2016: 2 · 2015: 2 · 2014: 2 · 2013: 3 · 2012: 4
- FWCI
- 2.10
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- European Journal of Pain (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
- Health Sciences › Medicine › Physiology › Pain Mechanisms and Treatments
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Automotive and Human Injury Biomechanics
- Keywords
- whiplash-associated disorders, health-related quality of life, thermal pain threshold, thermal hyperalgesia, neck pain, trapezius, thenar muscles, patient subgrouping, chronic pain, SF-36, pain intensity
- MeSH terms
- Adult, Cold Temperature, Female, Hot Temperature, Humans, Hyperalgesia, Male, Middle Aged, Neck Muscles, Pain Measurement, Quality of Life, Whiplash Injuries, Pain Threshold, Neck Pain
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